Sucrase-Isomaltase Complex
"Sucrase-Isomaltase Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme complex found in the brush border membranes of the small intestine. It is believed to be an enzyme complex with different catalytic sites. Its absence is manifested by an inherited disease called sucrase-isomaltase deficiency.
| Descriptor ID |
D013394
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| MeSH Number(s) |
D05.500.562.875 D08.811.277.450.329.738.700 D08.811.277.450.770.800 D08.811.600.850
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| Concept/Terms |
Sucrase-Isomaltase Complex- Sucrase-Isomaltase Complex
- Complex, Sucrase-Isomaltase
- Sucrase Isomaltase Complex
- Complex, Sucrase Isomaltase
- Isomaltase Complex, Sucrase
|
Below are MeSH descriptors whose meaning is more general than "Sucrase-Isomaltase Complex".
Below are MeSH descriptors whose meaning is more specific than "Sucrase-Isomaltase Complex".
This graph shows the total number of publications written about "Sucrase-Isomaltase Complex" by people in this website by year, and whether "Sucrase-Isomaltase Complex" was a major or minor topic of these publications.
Below are the most recent publications written about "Sucrase-Isomaltase Complex" by people in Profiles.
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Genetic and acquired sucrase-isomaltase deficiency: A clinical review. J Pediatr Gastroenterol Nutr. 2024 Apr; 78(4):774-782.
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Hypomorphic SI genetic variants are associated with childhood chronic loose stools. PLoS One. 2020; 15(5):e0231891.
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MiR-26a and miR-26b downregulate the expression of sucrase-isomaltase enzyme: A new chapter in diabetes treatment. Biochem Biophys Res Commun. 2019 10 29; 519(1):192-197.
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Increased Prevalence of Rare Sucrase-isomaltase Pathogenic Variants in Irritable Bowel Syndrome Patients. Clin Gastroenterol Hepatol. 2018 10; 16(10):1673-1676.
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Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome. Gut. 2018 02; 67(2):263-270.
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Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo. Am J Physiol Gastrointest Liver Physiol. 2006 May; 290(5):G1016-24.
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A novel colonic repressor element regulates intestinal gene expression by interacting with Cux/CDP. Mol Cell Biol. 2002 Aug; 22(15):5467-78.
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Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A. J Clin Invest. 1996 Aug 01; 98(3):641-9.