Ketoglutarate Dehydrogenase Complex
"Ketoglutarate Dehydrogenase Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
No definition found.
Descriptor ID |
D007655
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MeSH Number(s) |
D05.500.562.468 D08.811.600.465 D08.811.682.657.350.750
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Concept/Terms |
Ketoglutarate Dehydrogenase Complex- Ketoglutarate Dehydrogenase Complex
- Complex, Ketoglutarate Dehydrogenase
- Dehydrogenase Complex, Ketoglutarate
- 2-Oxoglutarate Dehydrogenase
- 2 Oxoglutarate Dehydrogenase
- Dehydrogenase, 2-Oxoglutarate
- 2-Oxoglutarate Dehydrogenase Complex
- 2 Oxoglutarate Dehydrogenase Complex
- Complex, 2-Oxoglutarate Dehydrogenase
- Dehydrogenase Complex, 2-Oxoglutarate
- Oxoglutarate Dehydrogenase
- Dehydrogenase, Oxoglutarate
- alpha-Ketoglutarate Dehydrogenase Complex
- Complex, alpha-Ketoglutarate Dehydrogenase
- Dehydrogenase Complex, alpha-Ketoglutarate
- alpha Ketoglutarate Dehydrogenase Complex
- 2-Keto-4-Hydroxyglutarate Dehydrogenase
- 2 Keto 4 Hydroxyglutarate Dehydrogenase
- Dehydrogenase, 2-Keto-4-Hydroxyglutarate
- alpha-Ketoglutarate Dehydrogenase
- Dehydrogenase, alpha-Ketoglutarate
- alpha Ketoglutarate Dehydrogenase
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Below are MeSH descriptors whose meaning is more general than "Ketoglutarate Dehydrogenase Complex".
Below are MeSH descriptors whose meaning is more specific than "Ketoglutarate Dehydrogenase Complex".
This graph shows the total number of publications written about "Ketoglutarate Dehydrogenase Complex" by people in this website by year, and whether "Ketoglutarate Dehydrogenase Complex" was a major or minor topic of these publications.
View timeline visualization
Year | Major Topic | Minor Topic | Total |
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1996 | 2 | 1 | 3 |
1999 | 1 | 0 | 1 |
2003 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2016 | 2 | 0 | 2 |
2018 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Ketoglutarate Dehydrogenase Complex" by people in Profiles.
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Bi-allelic variants in OGDHL cause a neurodevelopmental spectrum disease featuring epilepsy, hearing loss, visual impairment, and ataxia. Am J Hum Genet. 2021 12 02; 108(12):2368-2384.
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Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex. ACS Chem Biol. 2020 08 21; 15(8):2041-2047.
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Metabolic interactions between dynamic bacterial subpopulations. Elife. 2018 05 29; 7.
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Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. Neuron. 2017 Jan 04; 93(1):115-131.
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Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart. Proc Natl Acad Sci U S A. 2016 09 13; 113(37):10436-41.
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Reactive oxygen species production in cardiac mitochondria after complex I inhibition: Modulation by substrate-dependent regulation of the NADH/NAD(+) ratio. Free Radic Biol Med. 2016 07; 96:22-33.
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Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina. J Biol Chem. 2016 Feb 26; 291(9):4698-710.
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OGDHL is a modifier of AKT-dependent signaling and NF-κB function. PLoS One. 2012; 7(11):e48770.
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A 'random steady-state' model for the pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase enzyme complexes. Phys Biol. 2010 Mar 12; 7:16016.
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Differential requirements of calcium for oxoglutarate dehydrogenase and mitochondrial nitric-oxide synthase under hypoxia: impact on the regulation of mitochondrial oxygen consumption. Comp Biochem Physiol A Mol Integr Physiol. 2005 Oct; 142(2):111-7.