"Glucokinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of enzymes that catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate. They are found in invertebrates and microorganisms, and are highly specific for glucose. (Enzyme Nomenclature, 1992) EC 2.7.1.2.
| Descriptor ID |
D005941
|
| MeSH Number(s) |
D08.811.913.696.620.250
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Glucokinase".
Below are MeSH descriptors whose meaning is more specific than "Glucokinase".
This graph shows the total number of publications written about "Glucokinase" by people in this website by year, and whether "Glucokinase" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 1 | 3 |
| 2001 | 1 | 1 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 2 | 4 | 6 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Glucokinase" by people in Profiles.
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Impact of the hepatoselective glucokinase activator TTP399 on ketoacidosis during insulin withdrawal in people with type 1 diabetes. Diabetes Obes Metab. 2022 08; 24(8):1439-1447.
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Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain. Diabetes. 2019 03; 68(3):654-664.
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Identification of the matricellular protein Fibulin-5 as a target molecule of glucokinase-mediated calcineurin/NFAT signaling in pancreatic islets. Sci Rep. 2017 05 24; 7(1):2364.
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Characterization of a novel glucokinase activator in rat and mouse models. PLoS One. 2014; 9(2):e88431.
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β-Cell proliferation after a partial pancreatectomy is independent of IRS-2 in mice. Endocrinology. 2014 May; 155(5):1643-52.
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Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells. Diabetes. 2013 Oct; 62(10):3448-58.
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iPSC-derived β cells model diabetes due to glucokinase deficiency. J Clin Invest. 2013 07; 123(7):3146-53.
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AMPK is involved in the regulation of incretin receptors expression in pancreatic islets under a low glucose concentration. PLoS One. 2013; 8(5):e64633.
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Effects of biotin supplementation in the diet on insulin secretion, islet gene expression, glucose homeostasis and beta-cell proportion. J Nutr Biochem. 2013 Jan; 24(1):169-77.
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Effect of guar gum on glucose and lipid metabolism in white sea bream Diplodus sargus. Fish Physiol Biochem. 2013 Apr; 39(2):159-69.