"NF-kappa B p50 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p105 precursor protein and is capable of forming dimeric complexes with itself or with TRANSCRIPTION FACTOR RELA. It regulates expression of GENES involved in immune and inflammatory responses.
| Descriptor ID |
D052002
|
| MeSH Number(s) |
D12.776.260.600.124 D12.776.660.600.124 D12.776.930.600.124
|
| Concept/Terms |
NF-kappa B p50 Subunit- NF-kappa B p50 Subunit
- NF kappa B p50 Subunit
- NFKB1 Transcription Factor
- Transcription Factor, NFKB1
- NF-kappa B p50
- NF kappa B p50
- p50, NF-kappa B
- NF-kappaB 50-kDa
- NF kappaB 50 kDa
|
Below are MeSH descriptors whose meaning is more general than "NF-kappa B p50 Subunit".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B p50 Subunit".
This graph shows the total number of publications written about "NF-kappa B p50 Subunit" by people in this website by year, and whether "NF-kappa B p50 Subunit" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 3 | 3 |
| 2005 | 4 | 4 | 8 |
| 2006 | 2 | 6 | 8 |
| 2007 | 4 | 4 | 8 |
| 2008 | 4 | 5 | 9 |
| 2009 | 4 | 2 | 6 |
| 2010 | 2 | 0 | 2 |
| 2011 | 2 | 2 | 4 |
| 2012 | 3 | 1 | 4 |
| 2013 | 2 | 3 | 5 |
| 2014 | 3 | 1 | 4 |
| 2015 | 2 | 3 | 5 |
| 2016 | 2 | 1 | 3 |
| 2017 | 0 | 3 | 3 |
| 2018 | 2 | 2 | 4 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 1 | 2 |
| 2023 | 1 | 0 | 1 |
Below are the most recent publications written about "NF-kappa B p50 Subunit" by people in Profiles.
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The multifunctional role of intrinsic disorder in NF-κB signaling. Biochem Soc Trans. 2023 12 20; 51(6):2085-2092.
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Detrimental NFKB1 missense variants affecting the Rel-homology domain of p105/p50. Front Immunol. 2022; 13:965326.
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An intrinsically disordered transcription activation domain increases the DNA binding affinity and reduces the specificity of NFκB p50/RelA. J Biol Chem. 2022 09; 298(9):102349.
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Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells. Front Immunol. 2021; 12:678036.
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Growth and differentiation factor 15 and NF-κB expression in benign prostatic biopsies and risk of subsequent prostate cancer detection. Cancer Med. 2021 05; 10(9):3013-3025.
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Multiplexed Functional Assessment of Genetic Variants in CARD11. Am J Hum Genet. 2020 12 03; 107(6):1029-1043.
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A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control. J Hepatol. 2020 05; 72(5):960-975.
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Exclusivity and Compensation in NFκB Dimer Distributions and IκB Inhibition. Biochemistry. 2019 05 28; 58(21):2555-2563.
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NF-κB-Associated Pain-Related Neuropeptide Expression in Patients with Degenerative Disc Disease. Int J Mol Sci. 2019 Feb 03; 20(3).
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Advances and highlights in primary immunodeficiencies in 2017. J Allergy Clin Immunol. 2018 10; 142(4):1041-1051.