"Replication Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.
| Descriptor ID |
D051818
|
| MeSH Number(s) |
D08.811.277.040.013.500.438 D08.811.277.040.025.024.438 D12.776.157.025.750.438 D12.776.260.702
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Replication Protein C".
Below are MeSH descriptors whose meaning is more specific than "Replication Protein C".
This graph shows the total number of publications written about "Replication Protein C" by people in this website by year, and whether "Replication Protein C" was a major or minor topic of these publications.
Below are the most recent publications written about "Replication Protein C" by people in Profiles.
-
Expanding the genetic and phenotypic landscape of replication factor C complex-related disorders: RFC4 deficiency is linked to a multisystemic disorder. Am J Hum Genet. 2024 Sep 05; 111(9):1970-1993.
-
PCNA activates the MutLγ endonuclease to promote meiotic crossing over. Nature. 2020 10; 586(7830):623-627.
-
Bioinformatics-Based Identification of Expanded Repeats: A Non-reference Intronic Pentamer Expansion in RFC1 Causes CANVAS. Am J Hum Genet. 2019 07 03; 105(1):151-165.
-
Tandem affinity purification of exosome and replication factor C complexes from the non-human infectious kinetoplastid parasite Crithidia fasciculata. Mol Biochem Parasitol. 2017 10; 217:19-22.
-
Break-induced telomere synthesis underlies alternative telomere maintenance. Nature. 2016 11 03; 539(7627):54-58.
-
Effect of chronic kidney disease on the expression of thiamin and folic acid transporters. Nephrol Dial Transplant. 2011 Jul; 26(7):2137-44.
-
Recognition of the ring-opened state of proliferating cell nuclear antigen by replication factor C promotes eukaryotic clamp-loading. J Am Chem Soc. 2010 Jun 02; 132(21):7372-8.
-
PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase delta. Mol Cell. 2009 Nov 25; 36(4):704-13.
-
The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase. Nucleic Acids Res. 2007; 35(5):1624-37.
-
Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response. Mol Biol Cell. 2005 Nov; 16(11):5269-82.