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Lewy Body Disease

"Lewy Body Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)


expand / collapse Publications
This graph shows the total number of publications written about "Lewy Body Disease" by people in this website by year, and whether "Lewy Body Disease" was a major or minor topic of these publications.
Below are the most recent publications written about "Lewy Body Disease" by people in Profiles.
  1. Hospice Use Among Medicare Beneficiaries With Parkinson Disease and Dementia With Lewy Bodies. JAMA Netw Open. 2025 Mar 03; 8(3):e250014.
    View in: PubMed
  2. Distinct subcellular localization of tau and alpha-synuclein in lewy body disease. Acta Neuropathol Commun. 2025 Jan 21; 13(1):14.
    View in: PubMed
  3. Concordance and test-retest consistency of sleep biomarker-based neurodegenerative disorder profiling. Sci Rep. 2024 12 28; 14(1):31234.
    View in: PubMed
  4. Cognitive decline profiles associated with lewy pathology in the context of Alzheimer's disease neuropathologic change. Alzheimers Res Ther. 2024 Dec 20; 16(1):270.
    View in: PubMed
  5. Orexin and Sleep Disturbances in Alpha-Synucleinopathies: a Systematic Review. Curr Neurol Neurosci Rep. 2024 Sep; 24(9):389-412.
    View in: PubMed
  6. Association of CSF α-Synuclein Seeding Amplification Assay Results With Clinical Features of Possible and Probable Dementia With Lewy Bodies. Neurology. 2024 Aug 13; 103(3):e209656.
    View in: PubMed
  7. Cerebral Glucose Metabolism Is a Valuable Predictor of Survival in Patients with Lewy Body Diseases. Ann Neurol. 2024 Sep; 96(3):539-550.
    View in: PubMed
  8. Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies. JAMA. 2024 04 16; 331(15):1298-1306.
    View in: PubMed
  9. α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway. Cell Death Dis. 2024 04 13; 15(4):264.
    View in: PubMed
  10. Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort. Alzheimers Dement. 2024 05; 20(5):3334-3341.
    View in: PubMed