"Multiple System Atrophy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
| Descriptor ID |
D019578
|
| MeSH Number(s) |
C10.177.575.550 C10.228.140.079.612 C10.228.662.550 C10.574.625
|
| Concept/Terms |
Multiple System Atrophy- Multiple System Atrophy
- Atrophy, Multiple System
- Multiple System Atrophies
- Multisystem Atrophy
- Atrophies, Multisystem
- Atrophy, Multisystem
- Multisystem Atrophies
- Multisystemic Atrophy
- Atrophies, Multisystemic
- Atrophy, Multisystemic
- Multisystemic Atrophies
- Multiple System Atrophy Syndrome
|
Below are MeSH descriptors whose meaning is more general than "Multiple System Atrophy".
Below are MeSH descriptors whose meaning is more specific than "Multiple System Atrophy".
This graph shows the total number of publications written about "Multiple System Atrophy" by people in this website by year, and whether "Multiple System Atrophy" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 3 | 0 | 3 |
| 1999 | 2 | 1 | 3 |
| 2002 | 1 | 2 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 3 | 1 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 3 | 1 | 4 |
| 2008 | 1 | 0 | 1 |
| 2009 | 4 | 0 | 4 |
| 2010 | 4 | 1 | 5 |
| 2011 | 4 | 2 | 6 |
| 2012 | 2 | 1 | 3 |
| 2013 | 4 | 2 | 6 |
| 2014 | 4 | 0 | 4 |
| 2015 | 7 | 0 | 7 |
| 2016 | 7 | 2 | 9 |
| 2017 | 7 | 0 | 7 |
| 2018 | 5 | 2 | 7 |
| 2019 | 8 | 0 | 8 |
| 2020 | 4 | 1 | 5 |
| 2021 | 4 | 0 | 4 |
| 2022 | 9 | 1 | 10 |
| 2023 | 9 | 1 | 10 |
| 2024 | 4 | 2 | 6 |
Below are the most recent publications written about "Multiple System Atrophy" by people in Profiles.
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Cryo-EM structure of a novel α-synuclein filament subtype from multiple system atrophy. FEBS Lett. 2025 Jan; 599(1):33-40.
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Orexin and Sleep Disturbances in Alpha-Synucleinopathies: a Systematic Review. Curr Neurol Neurosci Rep. 2024 Sep; 24(9):389-412.
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Genome sequence analyses identify novel risk loci for multiple system atrophy. Neuron. 2024 Jul 03; 112(13):2142-2156.e5.
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Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies. JAMA. 2024 04 16; 331(15):1298-1306.
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Frequency and outcomes of gastrostomy insertion in a longitudinal cohort study of atypical parkinsonism. Eur J Neurol. 2024 Jun; 31(6):e16258.
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CSF1R-mediated myeloid cell depletion shifts the ratio of motor cortical excitatory to inhibitory neurons in a multiple system atrophy model. Exp Neurol. 2024 Apr; 374:114706.
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Feasibility and considerations of epsin2 as a candidate target for multiple system atrophy treatment. Expert Opin Ther Targets. 2023 Jul-Dec; 27(11):1031-1034.
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Differential involvement of amyloidogenic evolvability in oligodendropathies; Multiple Sclerosis and Multiple System Atrophy. Prion. 2023 12; 17(1):29-34.
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Striatal and thalamic automatic segmentation, morphology, and clinical correlates in Parkinsonism: Parkinson's disease, multiple system atrophy and progressive supranuclear palsy. Psychiatry Res Neuroimaging. 2023 10; 335:111719.
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Pharmacological inhibition of FABP7 by MF 6 counteracts cerebellum dysfunction in an experimental multiple system atrophy mouse model. Acta Pharmacol Sin. 2024 Jan; 45(1):66-75.