"CD48 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 40-45 KDa GPI-linked protein in the SLAM family that consists of two IMMUNOGLOBULIN C2-SET DOMAINS. It is expressed on the surface of a variety of cells with immune functions, including THYMOCYTES; mature B-LYMPHOCYTES and T-LYMPHOCYTES; NATURAL KILLER CELLS; DENDRITIC CELLS; MAST CELLS; and EOSINOPHILS. It binds to CD2 and 2B4 (CD244) receptors to activate and modulate the immunologic response.
| Descriptor ID |
D000071178
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| MeSH Number(s) |
D12.776.395.550.448.180 D12.776.395.550.736.250 D12.776.543.484.500.180 D12.776.543.550.418.180 D12.776.543.550.746.250 D12.776.543.750.705.970.250
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| Concept/Terms |
CD48 Antigen- CD48 Antigen
- Antigen, CD48
- Signaling Lymphocytic Activation Molecule 2
- Blast1 Antigen
- B-Lymphocyte Activation Marker BLAST-1
- B Lymphocyte Activation Marker BLAST 1
- Leukocyte Antigen MEM-102
- Leukocyte Antigen MEM 102
- MEM-102, Leukocyte Antigen
- Signal-Transducing Glycoprotein-60
- Glycoprotein-60, Signal-Transducing
- Signal Transducing Glycoprotein 60
- P41 Antigen
- Antigen, P41
- SLAM Family Member 2
- SLAMF2 Protein
- BCM1 Surface Antigen
- Surface Antigen, BCM1
- Signaling Lymphocytic Activation Molecule Family Member 2
- MRC OX-45 Antigen
- Antigen, MRC OX-45
- MRC OX 45 Antigen
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Below are MeSH descriptors whose meaning is more general than "CD48 Antigen".
Below are MeSH descriptors whose meaning is more specific than "CD48 Antigen".
This graph shows the total number of publications written about "CD48 Antigen" by people in this website by year, and whether "CD48 Antigen" was a major or minor topic of these publications.
Below are the most recent publications written about "CD48 Antigen" by people in Profiles.
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Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48. Cell Rep. 2024 Mar 26; 43(3):113800.
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Detection of human herpesvirus-6 in adult central nervous system tumors: predominance of early and late viral antigens in glial tumors. J Neurooncol. 2009 Oct; 95(1):49-60.
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Mutational analysis of the human 2B4 (CD244)/CD48 interaction: Lys68 and Glu70 in the V domain of 2B4 are critical for CD48 binding and functional activation of NK cells. J Immunol. 2005 Jul 15; 175(2):1005-13.
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Glycosylphosphatidylinositol-anchored receptor-mediated bacterial endocytosis. FEMS Microbiol Lett. 2001 Apr 13; 197(2):131-8.
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Involvement of cellular caveolae in bacterial entry into mast cells. Science. 2000 Aug 04; 289(5480):785-8.
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2B4-mediated activation of human natural killer cells. Mol Immunol. 2000 Jun; 37(9):493-501.
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Bacteria-host cell interaction mediated by cellular cholesterol/glycolipid-enriched microdomains. Biosci Rep. 1999 Oct; 19(5):421-32.
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In vivo functions mediated by the p41 isoform of the MHC class II-associated invariant chain. J Immunol. 1997 Jan 01; 158(1):187-99.
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Physical and genetic linkage of the genes encoding Ly-9 and CD48 on mouse and human chromosomes 1. Immunogenetics. 1995; 42(1):59-62.
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The NH2-terminal domain of rat CD2 binds rat CD48 with a low affinity and binding does not require glycosylation of CD2. Eur J Immunol. 1993 Jun; 23(6):1373-7.