Class II Phosphatidylinositol 3-Kinases
"Class II Phosphatidylinositol 3-Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of phosphatidylinositol 3-kinases that have specificity for 1-phosphatidylinositol and 1-phosphatidylinositol 4-phosphate. Members of this subclass consist of a single subunit structure and are regulated by RECEPTOR TYROSINE KINASES; CYTOKINE RECEPTORS; and INTEGRINS.
| Descriptor ID |
D058541
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| MeSH Number(s) |
D08.811.913.696.620.500.100.200 D08.811.913.696.620.500.200.200 D12.776.476.168
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| Concept/Terms |
Class II Phosphatidylinositol 3-Kinases- Class II Phosphatidylinositol 3-Kinases
- Class II Phosphatidylinositol 3 Kinases
- Phosphatidylinositol 3-Kinase, Class II
- Phosphatidylinositol 3 Kinase, Class II
Phosphoinositide-3-Kinase, Class II, gamma Polypeptide- Phosphoinositide-3-Kinase, Class II, gamma Polypeptide
- PtdIns-3-Kinase C2 gamma
- PtdIns 3 Kinase C2 gamma
- Phosphoinositide-3-Kinase, Class 2, gamma Polypeptide
- Phosphatidylinositol-4-Phosphate 3-Kinase C2 Domain-Containing gamma Polypeptide
- Phosphatidylinositol 4 Phosphate 3 Kinase C2 Domain Containing gamma Polypeptide
- Phosphoinositide 3-Kinase-C2-gamma
- Phosphoinositide 3 Kinase C2 gamma
Phosphoinositide-3-Kinase, Class II, alpha Polypeptide- Phosphoinositide-3-Kinase, Class II, alpha Polypeptide
- PtdIns-3-Kinase C2 alpha
- PtdIns 3 Kinase C2 alpha
- Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide
- Phosphatidylinositol-4-Phosphate 3-Kinase C2 Domain-Containing alpha Polypeptide
- Phosphatidylinositol 4 Phosphate 3 Kinase C2 Domain Containing alpha Polypeptide
- Phosphoinositide 3-Kinase C2alpha
- Phosphoinositide 3 Kinase C2alpha
Phosphoinositide-3-Kinase, Class II, beta Polypeptide- Phosphoinositide-3-Kinase, Class II, beta Polypeptide
- PtdIns-3-Kinase C2 beta
- PtdIns 3 Kinase C2 beta
- Phosphoinositide-3-Kinase, Class 2, beta Polypeptide
- Phosphatidylinositol-4-Phosphate 3-Kinase C2 Domain-Containing beta Polypeptide
- Phosphatidylinositol 4 Phosphate 3 Kinase C2 Domain Containing beta Polypeptide
- Phosphoinositide 3-Kinase-C2-beta
- Phosphoinositide 3 Kinase C2 beta
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Below are MeSH descriptors whose meaning is more general than "Class II Phosphatidylinositol 3-Kinases".
Below are MeSH descriptors whose meaning is more specific than "Class II Phosphatidylinositol 3-Kinases".
This graph shows the total number of publications written about "Class II Phosphatidylinositol 3-Kinases" by people in this website by year, and whether "Class II Phosphatidylinositol 3-Kinases" was a major or minor topic of these publications.
Below are the most recent publications written about "Class II Phosphatidylinositol 3-Kinases" by people in Profiles.
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A postsynaptic PI3K-cII dependent signaling controller for presynaptic homeostatic plasticity. Elife. 2018 01 05; 7.
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Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity. Cell Rep. 2015 Dec 01; 13(9):1881-94.
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Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase. Biochem J. 2014 Nov 01; 463(3):413-27.
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Phosphoinositide regulation of integrin trafficking required for muscle attachment and maintenance. PLoS Genet. 2011 Feb 10; 7(2):e1001295.
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Baculovirus production of fully-active phosphoinositide 3-kinase alpha as a p85alpha-p110alpha fusion for X-ray crystallographic analysis with ATP competitive enzyme inhibitors. Protein Expr Purif. 2010 Oct; 73(2):167-76.
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The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells. Mol Biol Cell. 2009 Sep; 20(17):3783-91.