"Activin Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity.
| Descriptor ID |
D029404
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.062 D12.776.543.750.750.400.820.500
|
| Concept/Terms |
Activin Receptors- Activin Receptors
- Receptor, Activin
- Activin Receptor-Like Kinases
- Activin Receptor like Kinases
- Kinases, Activin Receptor-like
- Receptor-like Kinases, Activin
- Activin Receptor
- Activin Receptor-like Kinase
- Activin Receptor like Kinase
- Kinase, Activin Receptor-like
- Receptor-like Kinase, Activin
|
Below are MeSH descriptors whose meaning is more general than "Activin Receptors".
Below are MeSH descriptors whose meaning is more specific than "Activin Receptors".
This graph shows the total number of publications written about "Activin Receptors" by people in this website by year, and whether "Activin Receptors" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
Below are the most recent publications written about "Activin Receptors" by people in Profiles.
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Cardiac function modulates endocardial cell dynamics to shape the cardiac outflow tract. Development. 2020 06 17; 147(12).
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Activin Type II Receptor Blockade for Treatment of Muscle Depletion in Chronic Obstructive Pulmonary Disease. A Randomized Trial. Am J Respir Crit Care Med. 2019 02 01; 199(3):313-320.
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Circulating microRNAs as Potential Biomarkers of Endothelial Dysfunction in Obese Children. Chest. 2016 Mar; 149(3):786-800.
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Regulatory role of BMP-9 in steroidogenesis by rat ovarian granulosa cells. J Steroid Biochem Mol Biol. 2015 Mar; 147:85-91.
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Acute modulation of synaptic plasticity of pyramidal neurons by activin in adult hippocampus. Front Neural Circuits. 2014; 8:56.
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Activation of vascular bone morphogenetic protein signaling in diabetes mellitus. Circ Res. 2011 Feb 18; 108(4):446-57.
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Activin-A and myostatin response and steroid regulation in human myometrium: disruption of their signalling in uterine fibroid. J Clin Endocrinol Metab. 2011 Mar; 96(3):755-65.
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FoxL2 Is required for activin induction of the mouse and human follicle-stimulating hormone beta-subunit genes. Mol Endocrinol. 2010 May; 24(5):1037-51.
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Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells. Stem Cells. 2009 Nov; 27(11):2655-66.
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Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate. Dev Biol. 2009 Nov 01; 335(1):120-31.