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Tessier et al., 2000 - Google Patents

Cloning and characterization of mammalian UDP-glucose glycoprotein: glucosyltransferase and the development of a specific substrate for this enzyme

Tessier et al., 2000

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Document ID
626988617167984420
Author
Tessier D
Dignard D
Zapun A
Radominska-Pandya A
Parodi A
Bergeron J
Thomas D
Publication year
Publication venue
Glycobiology

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The endoplasmic reticulum enzyme UDP-glucose glycoprotein: glucosyltransferase (UGGT) has the unique property of recognizing incompletely folded glycoproteins and, if they carry an N-linked Man9GlcNAc2 oligosaccharide, of catalyzing the addition of a glucose residue …
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
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    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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