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Roth et al. - Google Patents

Correction of autoimmune IL2RA mutations in primary human T cells using non-viral genome targeting

Roth et al.

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Document ID
5974733350794418192
Author
Roth T
Yu R
Shifrut E
Hiatt J
Li H

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The full promise of cell-based immunotherapies depends on technology to engineer and correct targeted genome sequences in primary human immune cells. CRISPR-Cas9 genome editing components can be electroporated into primary cells for gene knock-out. To …
Continue reading at www.researchgate.net (PDF) (other versions)

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