ZW17890A1 - Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives - Google Patents

Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives

Info

Publication number: ZW17890A1
Authority: ZW; Zimbabwe
Prior art keywords: 6alkyl; aryl; compounds; dihydroimidazo; thiazole derivatives
Prior art date: 1989-11-24

Application number

ZW178/90A

Other languages

English (en)

Inventor

Herman Margaretha Raeym Alfons

Frans Corneel Roevens Leopold

Joannes Carolus Van Laer Willy

Pierre Frans Van Wauwe Jean

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-24

Filing date

1990-11-23

Publication date

1992-07-08

1990-11-23 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1992-07-08 Publication of ZW17890A1 publication Critical patent/ZW17890A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)

ZW178/90A 1989-11-24 1990-11-23 Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives ZW17890A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US44084289A	1989-11-24	1989-11-24

Publications (1)

Publication Number	Publication Date
ZW17890A1 true ZW17890A1 (en)	1992-07-08

Family

ID=23750399

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZW178/90A ZW17890A1 (en)	1989-11-24	1990-11-23	Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives

Country Status (25)

Country	Link
EP (1)	EP0430334B1 (sh)
JP (1)	JPH03170487A (sh)
KR (1)	KR910009714A (sh)
CN (1)	CN1032754C (sh)
AT (1)	ATE127795T1 (sh)
AU (1)	AU630766B2 (sh)
BG (1)	BG60587B1 (sh)
CA (1)	CA2028756A1 (sh)
CZ (1)	CZ281422B6 (sh)
DE (1)	DE69022370T2 (sh)
FI (1)	FI93459C (sh)
HU (1)	HU206361B (sh)
IE (1)	IE67656B1 (sh)
IL (1)	IL96435A (sh)
MY (1)	MY131024A (sh)
NO (1)	NO300065B1 (sh)
NZ (1)	NZ236026A (sh)
PL (1)	PL165413B1 (sh)
PT (1)	PT95978B (sh)
RO (1)	RO108869B1 (sh)
RU (1)	RU2051153C1 (sh)
YU (1)	YU47955B (sh)
ZA (1)	ZA909445B (sh)
ZM (1)	ZM5390A1 (sh)
ZW (1)	ZW17890A1 (sh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0524055A1 (fr) *	1991-07-19	1993-01-20	Synthelabo	Dérivés d'imidazo[2,1-b]benzothiazole-3-acétamide, leur préparation et leur application en thérapeutique
US6165253A (en) *	1994-05-23	2000-12-26	New Jersey Institute Of Technology	Apparatus for removal of volatile organic compounds from gaseous mixtures
EP1797880A3 (en) *	1999-01-29	2010-04-28	Board Of Trustees Of The University Of Illinois	P53 inhibitors and their use for the treatment of cancer, hyperthermia, hypoxia, a burn, trauma to the central nervous system, a seizure, acute inflammation, tissue ageing, preservation of organs for transplant and preparation of a host for bone marrow transplant
ATE380548T1 (de)	1999-01-29	2007-12-15	Univ Illinois	Verwendung von p53 inhibitoren zur behandlung von nebenerscheinungen bei der krebstherapie
RU2584609C2 (ru)	2004-09-28	2016-05-20	Кварк Фармасьютикалс, Инк.	Олигорибонуклеотиды и способы их применения для лечения острой почечной недостаточности
US7825099B2 (en)	2006-01-20	2010-11-02	Quark Pharmaceuticals, Inc.	Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
US7910566B2 (en)	2006-03-09	2011-03-22	Quark Pharmaceuticals Inc.	Prevention and treatment of acute renal failure and other kidney diseases by inhibition of p53 by siRNA
WO2009001359A2 (en)	2007-06-27	2008-12-31	Quark Pharmaceuticals, Inc.	Compositions and methods for inhibiting expression of pro-apoptotic genes
CN104557979A (zh) *	2013-10-23	2015-04-29	丹阳恒安化学科技研究所有限公司	盐酸左旋咪唑的制备方法
RU2763739C1 (ru) *	2021-06-28	2021-12-30	Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ)	(Z)-9-ароил-8-гидрокси-6-(2-гидроксифенил)-2-(((Z)-2-оксоиндолин-3-илиден)гидразоно)-1-тиа-3,6-диазаспиро[4.4]нон-8-ен-4,7-дионы, обладающие противомикробной активностью
US20250042920A1 (en) *	2021-11-29	2025-02-06	Ocean University Of China	Imidazothiazole derivative, preparation method therefor, and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU409983B2 (en) *	1965-07-19	1970-12-31	Imperial Chemical Industries Of Australia New Zealand Limited	Process for the manufacture of thia zolidines and thiazolidines produced thereby
GB1444743A (en) *	1973-09-20	1976-08-04	Pfizer Ltd	7-substituted imidazo-1,1-b-thiazolium and 9-substituted thiazolo-3,2-a-benzimidazolium derivatives having hypogly caemic and/or growth promotant properties
US4340738A (en) *	1979-06-21	1982-07-20	Janssen Pharmaceutica, N.V.	2,3-Dihydro-imidazo[2,1-b]benzothiazoles

1990
- 1990-10-29 CA CA002028756A patent/CA2028756A1/en not_active Abandoned
- 1990-11-09 NZ NZ236026A patent/NZ236026A/xx unknown
- 1990-11-15 AT AT90203031T patent/ATE127795T1/de active
- 1990-11-15 EP EP90203031A patent/EP0430334B1/en not_active Expired - Lifetime
- 1990-11-15 DE DE69022370T patent/DE69022370T2/de not_active Expired - Fee Related
- 1990-11-17 JP JP2310193A patent/JPH03170487A/ja active Pending
- 1990-11-20 YU YU220890A patent/YU47955B/sh unknown
- 1990-11-21 MY MYPI90002052A patent/MY131024A/en unknown
- 1990-11-21 AU AU66809/90A patent/AU630766B2/en not_active Ceased
- 1990-11-22 IL IL9643590A patent/IL96435A/en not_active IP Right Cessation
- 1990-11-22 BG BG93298A patent/BG60587B1/bg unknown
- 1990-11-22 CZ CS905803A patent/CZ281422B6/cs unknown
- 1990-11-23 FI FI905788A patent/FI93459C/fi not_active IP Right Cessation
- 1990-11-23 HU HU907633A patent/HU206361B/hu not_active IP Right Cessation
- 1990-11-23 PL PL90287907A patent/PL165413B1/pl unknown
- 1990-11-23 ZW ZW178/90A patent/ZW17890A1/xx unknown
- 1990-11-23 NO NO905086A patent/NO300065B1/no unknown
- 1990-11-23 ZA ZA909445A patent/ZA909445B/xx unknown
- 1990-11-23 RU SU904831684A patent/RU2051153C1/ru active
- 1990-11-23 RO RO146390A patent/RO108869B1/ro unknown
- 1990-11-23 ZM ZM53/90A patent/ZM5390A1/xx unknown
- 1990-11-23 IE IE424190A patent/IE67656B1/en not_active IP Right Cessation
- 1990-11-23 KR KR1019900019029A patent/KR910009714A/ko not_active Application Discontinuation
- 1990-11-23 PT PT95978A patent/PT95978B/pt not_active IP Right Cessation
- 1990-11-24 CN CN90109407A patent/CN1032754C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUT59414A (en)	1992-05-28
RO108869B1 (ro)	1994-09-30
AU6680990A (en)	1991-05-30
BG93298A (bg)	1993-12-24
YU220890A (sh)	1992-12-21
CN1032754C (zh)	1996-09-11
DE69022370D1 (de)	1995-10-19
PL287907A1 (en)	1992-04-21
FI93459C (fi)	1995-04-10
DE69022370T2 (de)	1996-03-14
NZ236026A (en)	1992-03-26
ATE127795T1 (de)	1995-09-15
ZM5390A1 (en)	1992-06-30
HU206361B (en)	1992-10-28
NO300065B1 (no)	1997-04-01
YU47955B (sh)	1996-07-24
AU630766B2 (en)	1992-11-05
IL96435A (en)	1995-03-15
KR910009714A (ko)	1991-06-28
IL96435A0 (en)	1991-08-16
FI905788A (fi)	1991-05-25
MY131024A (en)	2007-07-31
CN1052117A (zh)	1991-06-12
FI905788A0 (fi)	1990-11-23
HU907633D0 (en)	1991-06-28
IE67656B1 (en)	1996-04-17
PT95978A (pt)	1991-09-13
EP0430334B1 (en)	1995-09-13
ZA909445B (en)	1992-07-29
EP0430334A1 (en)	1991-06-05
PT95978B (pt)	1998-01-30
PL165413B1 (pl)	1994-12-30
RU2051153C1 (ru)	1995-12-27
NO905086L (no)	1991-05-27
CZ580390A3 (en)	1996-06-12
CZ281422B6 (cs)	1996-09-11
JPH03170487A (ja)	1991-07-24
IE904241A1 (en)	1991-06-05
BG60587B1 (bg)	1995-09-29
NO905086D0 (no)	1990-11-23
CA2028756A1 (en)	1991-05-25
FI93459B (fi)	1994-12-30

Publication	Publication Date	Title
AU3821089A (en)	1990-01-25	2-phenyl-purin-6-one derivatives for use as bronchodilators and vasodilators
AU630766B2 (en)	1992-11-05	Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b) thiazole derivatives
HU9202047D0 (en)	1992-09-28	Method for producing n-phenyl-thiourea derivatives and pharmaceutical prepartives containing these compounds as active agents
PT90034A (pt)	1989-11-10	Processo para a preparacao de tetra-hidroimidazo-{1,4}benzodiazepina-2-onas
ZA903663B (en)	1992-01-29	Antirhinoviral(thio)morpholinyl and piperazinyl alkylphenol ethers
AU5494290A (en)	1990-11-15	Antirhinoviral pyridazinamines
PT91613A (pt)	1990-03-30	Process for the preparation of antihypertensive 3-piperidinyl-indazole derivatives
DE3362523D1 (en)	1986-04-17	Optically active imidazolylpropanol compounds, and their production and use