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ZA988508B - Novel stereoselective processes for the preparation of gabapentin and anologues thereof - Google Patents

Novel stereoselective processes for the preparation of gabapentin and anologues thereof

Info

Publication number
ZA988508B
ZA988508B ZA988508A ZA988508A ZA988508B ZA 988508 B ZA988508 B ZA 988508B ZA 988508 A ZA988508 A ZA 988508A ZA 988508 A ZA988508 A ZA 988508A ZA 988508 B ZA988508 B ZA 988508B
Authority
ZA
South Africa
Prior art keywords
gabapentin
preparation
anologues
stereoselective processes
novel stereoselective
Prior art date
Application number
ZA988508A
Other languages
English (en)
Inventor
Justin Stephen Bryans
Andrew Ian Morrell
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA988508B publication Critical patent/ZA988508B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA988508A 1997-09-18 1998-09-17 Novel stereoselective processes for the preparation of gabapentin and anologues thereof ZA988508B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5920497P 1997-09-18 1997-09-18

Publications (1)

Publication Number Publication Date
ZA988508B true ZA988508B (en) 1999-03-30

Family

ID=22021467

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA988508A ZA988508B (en) 1997-09-18 1998-09-17 Novel stereoselective processes for the preparation of gabapentin and anologues thereof

Country Status (20)

Country Link
US (1) US6465689B1 (xx)
EP (1) EP1015415B1 (xx)
JP (1) JP3878809B2 (xx)
KR (1) KR100563894B1 (xx)
AT (1) ATE239695T1 (xx)
AU (1) AU752444B2 (xx)
BR (1) BR9812351A (xx)
CA (1) CA2295993C (xx)
DE (1) DE69814420T2 (xx)
DK (1) DK1015415T3 (xx)
ES (1) ES2197493T3 (xx)
HU (1) HUP0004582A3 (xx)
IL (2) IL133782A0 (xx)
IS (1) IS2198B (xx)
NO (1) NO326227B1 (xx)
NZ (1) NZ502786A (xx)
PL (1) PL192180B1 (xx)
PT (1) PT1015415E (xx)
WO (1) WO1999014184A1 (xx)
ZA (1) ZA988508B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10203122A1 (de) 2002-01-25 2003-07-31 Gruenenthal Gmbh Verfahren zur Herstellung von substituierten Acrylsäureestern bzw. deren Einsatz zur Herstellung von substituierten gamma-Aminosäuren
US7439387B2 (en) 2003-04-21 2008-10-21 Matrix Laboratories Ltd. Process for the preparation of Gabapentin form-II
US20050187295A1 (en) * 2004-02-19 2005-08-25 Surendra Kalyan Processes for the preparation of gabapentin
EP1763503A1 (en) 2004-03-17 2007-03-21 Hikal Limited 4-t-butylgabapentin and its synthesis
US7632864B2 (en) 2004-03-17 2009-12-15 Hikal Ltd. Gabapentin analogues and process thereof
US7442834B2 (en) 2006-06-12 2008-10-28 Zhejiang Chiral Medicine Chemicals Co., Ltd. Process suitable for industrial scale production of gabapentin
WO2013190357A1 (en) * 2012-06-18 2013-12-27 Hikal Limited A process for the preparation of gabapentin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3928182A1 (de) * 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von gabapentin
NZ326669A (en) 1996-02-07 2001-05-25 Warner Lambert Co Thiopyran or pyran derivatives useful as pharmaceutical agents
SK282848B6 (sk) 1996-03-14 2002-12-03 Warner-Lambert Company Premostené cyklické aminokyseliny, farmaceutická kompozícia obsahujúca tieto aminokyseliny

Also Published As

Publication number Publication date
IS2198B (is) 2007-02-15
PL339296A1 (en) 2000-12-04
IL133782A (en) 2006-12-31
BR9812351A (pt) 2000-09-19
IL133782A0 (en) 2001-04-30
ATE239695T1 (de) 2003-05-15
DE69814420T2 (de) 2003-11-27
CA2295993A1 (en) 1999-03-25
JP2001516738A (ja) 2001-10-02
AU752444B2 (en) 2002-09-19
KR100563894B1 (ko) 2006-03-24
ES2197493T3 (es) 2004-01-01
PT1015415E (pt) 2003-09-30
HUP0004582A3 (en) 2002-01-28
NO20001404D0 (no) 2000-03-17
DK1015415T3 (da) 2003-07-21
DE69814420D1 (de) 2003-06-12
KR20010024079A (ko) 2001-03-26
PL192180B1 (pl) 2006-09-29
NZ502786A (en) 2002-05-31
EP1015415A1 (en) 2000-07-05
HUP0004582A2 (hu) 2001-05-28
US6465689B1 (en) 2002-10-15
NO326227B1 (no) 2008-10-20
WO1999014184A1 (en) 1999-03-25
CA2295993C (en) 2004-05-04
NO20001404L (no) 2000-03-17
JP3878809B2 (ja) 2007-02-07
EP1015415B1 (en) 2003-05-07
IS5355A (is) 2000-05-22
AU8779198A (en) 1999-04-05

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