ZA974334B - Fluorinated Vitamin D3 analogs. - Google Patents

Fluorinated Vitamin D3 analogs.

Info

Publication number: ZA974334B
Authority: ZA; South Africa
Prior art keywords: analogs; fluorinated vitamin; fluorinated; vitamin
Prior art date: 1996-05-23

Application number

ZA9704334A

Other languages

English (en)

Inventor

Bernard Michael Hennessy

Milan Radoje Uskokovic

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-23

Filing date

1997-05-19

Publication date

1997-11-24

1997-05-19 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1997-11-24 Publication of ZA974334B publication Critical patent/ZA974334B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Hematology (AREA)
Oncology (AREA)
Diabetes (AREA)
Obesity (AREA)
Nutrition Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA9704334A 1996-05-23 1997-05-19 Fluorinated Vitamin D3 analogs. ZA974334B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US1818796P	1996-05-23	1996-05-23

Publications (1)

Publication Number	Publication Date
ZA974334B true ZA974334B (en)	1997-11-24

Family

ID=21786696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9704334A ZA974334B (en)	1996-05-23	1997-05-19	Fluorinated Vitamin D3 analogs.

Country Status (30)

Country	Link
US (1)	US5888994A (xx)
EP (1)	EP0808831B1 (xx)
JP (1)	JP2858571B2 (xx)
KR (1)	KR100237523B1 (xx)
CN (1)	CN1081184C (xx)
AR (1)	AR007240A1 (xx)
AT (1)	ATE195514T1 (xx)
AU (1)	AU720098B2 (xx)
BR (1)	BR9703373A (xx)
CA (1)	CA2204478C (xx)
CO (1)	CO4840512A1 (xx)
CZ (1)	CZ157997A3 (xx)
DE (1)	DE69702812T2 (xx)
DK (1)	DK0808831T3 (xx)
ES (1)	ES2150719T3 (xx)
GR (1)	GR3034832T3 (xx)
HR (1)	HRP970274A2 (xx)
HU (1)	HUP9700927A3 (xx)
IL (1)	IL120842A0 (xx)
MA (1)	MA24345A1 (xx)
NO (1)	NO971934L (xx)
NZ (1)	NZ314838A (xx)
PL (1)	PL320131A1 (xx)
PT (1)	PT808831E (xx)
SG (1)	SG50831A1 (xx)
TR (1)	TR199700418A2 (xx)
TW (1)	TW374762B (xx)
UY (1)	UY24563A1 (xx)
YU (1)	YU19997A (xx)
ZA (1)	ZA974334B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO971934L (no) *	1996-05-23	1997-11-24	Hoffmann La Roche	Flourinerte vitamin D3 -analoger
CA2289209C (en) *	1997-05-16	2006-07-25	Women & Infants Hospital	Cyclic ether vitamin d3 compounds, 1.alpha. (oh) 3-epi-vitamin d3 compounds and uses thereof
US6017908A (en) *	1997-05-16	2000-01-25	Women And Infants Hospital	3-EPI vitamin D2 compounds and uses thereof
AU1022999A (en) *	1997-09-08	1999-03-29	F. Hoffmann-La Roche Ag	1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
AU3390400A (en) *	1999-03-05	2000-09-21	Johns Hopkins University, The	Regulating skin appearance and composition with a fluorinated vitamin d3 analog compound
US7148211B2 (en) *	2002-09-18	2006-12-12	Genzyme Corporation	Formulation for lipophilic agents
US20080293647A1 (en)	2004-11-12	2008-11-27	Luciano Adorini	Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer
DK1993559T3 (en)	2006-02-03	2016-10-03	Opko Renal Llc	Treatment of vitamin D deficiency and MALFUNCTION with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3
SI2679228T1 (en)	2006-06-21	2018-06-29	Opko Ireland Global Holdings, Ltd.	THERAPY WITH THE USE OF VITAMIN D ADDITIONAL FIBER AND HORMON RESISTANCE OF VITAMIN D
DK2148684T3 (da)	2007-04-25	2013-04-22	Cytochroma Inc	Fremgangsmåde til behandling af vitamin D-insufficiens og -deficiens
SI2148661T1 (sl)	2007-04-25	2013-04-30	Cytochroma Inc.	Nadzorovano oralno sproĹˇÄŤanje sestavkov, ki vsebujejo spojino vitamina D in voskasti naosilec
RS60087B1 (sr)	2010-03-29	2020-05-29	Opko Ireland Global Holdings Ltd	Postupci i kompozicije za snižavanje nivoa paratireoidnog hormona
WO2012065050A1 (en)	2010-11-12	2012-05-18	Wisconsin Alumni Research Foundation	22-haloacetoxy-homopregnacalciferol analogs and their uses
KR101847947B1 (ko)	2013-03-15	2018-05-28	옵코 아이피 홀딩스 Ⅱ 인코포레이티드	안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en)	2014-08-07	2019-03-05	Opko Ireland Global Holdings, Ltd.	Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
US11173168B2 (en)	2016-03-28	2021-11-16	Eirgen Pharma Ltd.	Methods of treating vitamin D insufficiency in chronic kidney disease

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5039671A (en) *	1984-12-19	1991-08-13	Hoffmann-La Roche Inc.	Trifluorinated-1α,25S-dihydroxy vitamin D3 compounds
US5145846A (en) *	1988-01-20	1992-09-08	Hoffmann-La Roche Inc.	Vitamin D3 analogs
US4804502A (en) *	1988-01-20	1989-02-14	Hoffmann-La Roche Inc.	Vitamin D compounds
GB9007236D0 (en) *	1990-03-30	1990-05-30	Leo Pharm Prod Ltd	Chemical compounds
GB9017890D0 (en) *	1990-08-15	1990-09-26	Leo Pharm Prod Ltd	Chemical compounds i
US5206230A (en) *	1991-06-05	1993-04-27	Daikin Industries, Ltd.	Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
US5210237A (en) *	1991-08-27	1993-05-11	Daikin Industries, Ltd.	Vitamin d3 analogues
US5200536A (en) *	1992-02-10	1993-04-06	Daikin Industries Ltd.	Fluorine-containing vitamin D3 analogues
GB9206648D0 (en) *	1992-03-26	1992-05-06	Leo Pharm Prod Ltd	Chemical compounds
ES2091515T3 (es) *	1992-05-20	1996-11-01	Hoffmann La Roche	Analogos fluorados de la vitamina d3.
CA2096105A1 (en) *	1992-10-07	1994-04-08	Enrico Giuseppe Baggiolini (Deceased)	Vitamin d3 fluorinated analogs
TW267161B (xx) *	1992-11-20	1996-01-01	Hoffmann La Roche
US5428029A (en) *	1993-11-24	1995-06-27	Hoffmann-La Roche Inc.	Vitamin D3 fluorinated analogs
US5384314B1 (en) *	1994-03-11	1997-08-05	Hoffmann La Roche	1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
NO971934L (no) *	1996-05-23	1997-11-24	Hoffmann La Roche	Flourinerte vitamin D3 -analoger

1997
- 1997-04-25 NO NO971934A patent/NO971934L/no unknown
- 1997-04-28 TW TW086105570A patent/TW374762B/zh active
- 1997-05-05 CA CA002204478A patent/CA2204478C/en not_active Expired - Fee Related
- 1997-05-12 SG SG1997001491A patent/SG50831A1/en unknown
- 1997-05-14 PT PT97107848T patent/PT808831E/pt unknown
- 1997-05-14 DE DE69702812T patent/DE69702812T2/de not_active Expired - Fee Related
- 1997-05-14 ES ES97107848T patent/ES2150719T3/es not_active Expired - Lifetime
- 1997-05-14 EP EP97107848A patent/EP0808831B1/en not_active Expired - Lifetime
- 1997-05-14 DK DK97107848T patent/DK0808831T3/da active
- 1997-05-14 AT AT97107848T patent/ATE195514T1/de not_active IP Right Cessation
- 1997-05-16 NZ NZ314838A patent/NZ314838A/en unknown
- 1997-05-16 IL IL12084297A patent/IL120842A0/xx unknown
- 1997-05-16 US US08/857,883 patent/US5888994A/en not_active Expired - Fee Related
- 1997-05-19 ZA ZA9704334A patent/ZA974334B/xx unknown
- 1997-05-20 HR HR60/018,187A patent/HRP970274A2/xx not_active Application Discontinuation
- 1997-05-20 YU YU19997A patent/YU19997A/sh unknown
- 1997-05-20 JP JP9129238A patent/JP2858571B2/ja not_active Expired - Fee Related
- 1997-05-21 HU HU9700927A patent/HUP9700927A3/hu unknown
- 1997-05-21 AR ARP970102157A patent/AR007240A1/es active IP Right Grant
- 1997-05-21 CO CO97027698A patent/CO4840512A1/es unknown
- 1997-05-21 MA MA24629A patent/MA24345A1/fr unknown
- 1997-05-22 KR KR1019970019921A patent/KR100237523B1/ko not_active IP Right Cessation
- 1997-05-22 CZ CZ971579A patent/CZ157997A3/cs unknown
- 1997-05-22 PL PL97320131A patent/PL320131A1/xx unknown
- 1997-05-22 AU AU23572/97A patent/AU720098B2/en not_active Ceased
- 1997-05-22 UY UY24563A patent/UY24563A1/es not_active Application Discontinuation
- 1997-05-23 TR TR97/00418A patent/TR199700418A2/xx unknown
- 1997-05-23 BR BR9703373A patent/BR9703373A/pt not_active Application Discontinuation
- 1997-05-23 CN CN97111050A patent/CN1081184C/zh not_active Expired - Fee Related
2000
- 2000-11-13 GR GR20000402519T patent/GR3034832T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
TW374762B (en)	1999-11-21
AR007240A1 (es)	1999-10-27
PL320131A1 (en)	1997-11-24
JP2858571B2 (ja)	1999-02-17
AU2357297A (en)	1997-11-27
HU9700927D0 (en)	1997-07-28
IL120842A0 (en)	1997-09-30
SG50831A1 (en)	1998-07-20
MA24345A1 (fr)	1998-07-01
ES2150719T3 (es)	2000-12-01
DE69702812T2 (de)	2001-01-25
NO971934L (no)	1997-11-24
KR970074763A (ko)	1997-12-10
UY24563A1 (es)	2000-12-29
US5888994A (en)	1999-03-30
JPH1045712A (ja)	1998-02-17
DE69702812D1 (de)	2000-09-21
YU19997A (sh)	1999-07-28
HUP9700927A3 (en)	1999-07-28
NO971934D0 (no)	1997-04-25
CO4840512A1 (es)	1999-09-27
EP0808831B1 (en)	2000-08-16
CN1081184C (zh)	2002-03-20
BR9703373A (pt)	1998-09-15
EP0808831A3 (en)	1999-02-03
TR199700418A3 (tr)	1997-12-21
KR100237523B1 (ko)	2000-01-15
CZ157997A3 (en)	1997-12-17
CA2204478A1 (en)	1997-11-23
HRP970274A2 (en)	1998-04-30
PT808831E (pt)	2000-12-29
AU720098B2 (en)	2000-05-25
ATE195514T1 (de)	2000-09-15
GR3034832T3 (en)	2001-02-28
NZ314838A (en)	1998-01-26
CN1169425A (zh)	1998-01-07
MX9703776A (es)	1998-06-30
TR199700418A2 (xx)	1997-12-21
HUP9700927A2 (hu)	1998-01-28
EP0808831A2 (en)	1997-11-26
CA2204478C (en)	2006-11-21
DK0808831T3 (da)	2001-01-02

Publication	Publication Date	Title
ZA974336B (en)	1997-11-24	Vitamin D3 analogs.
ZA974334B (en)	1997-11-24	Fluorinated Vitamin D3 analogs.
HK1019873A1 (en)	2000-03-03	Illudin analogs useful as antitumor agents.
ZA200110487B (en)	2003-03-20	Vitamin D3 Analogs.
ZA9711567B (en)	1998-06-24	Compounds.
ZA97944B (en)	1997-08-05	N: 1 Transcoder.
ZA975861B (en)	1998-01-30	Bromotiacumicin compounds.
SG70010A1 (en)	2000-01-25	Fluorinated vitamin d3 analogs
ZA974052B (en)	1998-01-14	New benzothiazolinones.
ZA974332B (en)	1997-11-24	Fluorinated vitamin D3 analogs.
ZA974056B (en)	1998-01-14	New thiazolopyridines.
ZA969923B (en)	1998-05-26	Antioxidant.
ZA979404B (en)	1998-06-01	Aspirinate compounds.
GB9601685D0 (en)	1996-03-27	Fluorinated compounds
SG24096A1 (en)	1996-02-10	Fluorinated vitamin D3 derivative
ZA933357B (en)	1993-11-22	Vitamin D3 fluorinated analogs
ZA9610663B (en)	1997-10-21	Wetsuit.
ZA978284B (en)	1998-03-24	Staircases.
GR2001944Y (en)	1997-09-17	Kinesthisiometer -goniometer feet.
ZA978645B (en)	1998-03-26	Lighting equipment.
ZA986155B (en)	2000-01-10	(+)-norcisapride.
SI1023263T1 (en)	2002-12-31	Novel vitamin d analogues