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ZA925351B - Beta-vinyl-and 8-ethinyl-quinolonecarboxylic acids - Google Patents

Beta-vinyl-and 8-ethinyl-quinolonecarboxylic acids

Info

Publication number
ZA925351B
ZA925351B ZA925351A ZA925351A ZA925351B ZA 925351 B ZA925351 B ZA 925351B ZA 925351 A ZA925351 A ZA 925351A ZA 925351 A ZA925351 A ZA 925351A ZA 925351 B ZA925351 B ZA 925351B
Authority
ZA
South Africa
Prior art keywords
vinyl
ethinyl
beta
quinolonecarboxylic acids
quinolonecarboxylic
Prior art date
Application number
ZA925351A
Inventor
Uwe Petersen
Petersen Uwe
Thomas Himmler
Himmler Thomas
Thomas Schenke
Schenke Thomas
Andreas Krebs
Krebs Andreas
Klaus Grohe
Grohe Klaus
Klaus-Dieter Bremm
Bremm Klaus-Dieter
Karl Georg Metzger
Georg Metzger Karl
Rainer Endermann
Endermann Rainer
Hans Joachim Zeiler
Joachim Zeiler Hans
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA925351B publication Critical patent/ZA925351B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Paints Or Removers (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

The invention relates to novel 8-vinyl- and 8-ethynyl- quinolonecarboxylic acids, a process for their preparation and antibacterial agents and feed additives containing them.
ZA925351A 1991-07-19 1992-07-17 Beta-vinyl-and 8-ethinyl-quinolonecarboxylic acids ZA925351B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4123918A DE4123918A1 (en) 1991-07-19 1991-07-19 8-VINYL AND 8-ETHINYL-CHINOLON CARBONIC ACIDS

Publications (1)

Publication Number Publication Date
ZA925351B true ZA925351B (en) 1993-04-28

Family

ID=6436512

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925351A ZA925351B (en) 1991-07-19 1992-07-17 Beta-vinyl-and 8-ethinyl-quinolonecarboxylic acids

Country Status (22)

Country Link
EP (1) EP0523512B1 (en)
JP (1) JP3174405B2 (en)
KR (1) KR100240608B1 (en)
AT (1) ATE147733T1 (en)
AU (1) AU658901B2 (en)
CA (1) CA2073993A1 (en)
CZ (1) CZ282037B6 (en)
DE (2) DE4123918A1 (en)
DK (1) DK0523512T3 (en)
ES (1) ES2097835T3 (en)
FI (1) FI103043B (en)
GR (1) GR3022305T3 (en)
HU (1) HU219910B (en)
IE (1) IE80557B1 (en)
IL (1) IL102520A (en)
MX (1) MX9204110A (en)
NO (1) NO302886B1 (en)
PL (1) PL171910B1 (en)
RU (1) RU2077533C1 (en)
SK (1) SK219192A3 (en)
TW (1) TW201309B (en)
ZA (1) ZA925351B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4121214A1 (en) * 1991-06-27 1993-01-14 Bayer Ag 7-AZAISOINDOLINYL CHINOLONE AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES
DE4230804A1 (en) * 1992-09-15 1994-03-17 Bayer Ag 7-isoindolinyl quinolone and naphthyridone derivatives
DE4303657A1 (en) * 1993-02-09 1994-08-11 Bayer Ag New quinolone and naphthyridonecarboxylic acid derivatives
KR950018003A (en) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 Novel quinolone derivatives and methods for their preparation
DE4418510A1 (en) * 1994-05-27 1995-11-30 Bayer Ag 1,9-bridged thiazolol [3,4-a] quinoline derivatives
DE4425659A1 (en) * 1994-07-20 1996-01-25 Bayer Ag New N1-diverse 6-fluoro-8-difluoromethoxy substituted quinolonecarboxylic acids
DE4427530A1 (en) * 1994-08-04 1996-02-08 Bayer Ag New 7-tri:cyclic amino-quinolone or naphthyridone derivs
ATE269320T1 (en) 1996-04-19 2004-07-15 Wakunaga Pharma Co Ltd NEW PYRIDONE CARBOXYLIC ACID DERIVATIVES OR SALTS OF THESE DERIVATIVES AND ANTIBACTERIAL AGENTS CONTAINING THEM AS THE ACTIVE INGREDIENTS
AU1040597A (en) * 1996-12-04 1998-06-29 Daiichi Pharmaceutical Co., Ltd. Substituted aminomethylpyrrolidine derivatives
EP1015445B1 (en) 1997-09-15 2009-02-25 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
KR101077755B1 (en) 2003-09-10 2011-10-27 교린 세이야꾸 가부시키 가이샤 7-(4-substituted 3-cyclopropylaminomethyl-1 pyrrolidinyl)quinolonecarboxylic acid derivative
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
US7842818B2 (en) 2005-09-28 2010-11-30 Daiichi Sankyo Company, Limited Process for preparation of tetrasubstituted 5-azaspiro[2.4]- heptane derivatives and optically active intermediates thereof
BRPI0709220A2 (en) 2006-03-28 2011-07-12 Procter & Gamble coupling process for preparation of quinolone intermediates
BRPI0709772B8 (en) 2006-03-28 2021-05-25 The Protecter & Gamble Company malate salts and polymorphs of (3s,5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
US8222407B2 (en) 2007-05-24 2012-07-17 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
KR20210006401A (en) * 2018-05-09 2021-01-18 바이엘 애니멀 헬스 게엠베하 Novel quinoline derivatives
RU2757741C1 (en) * 2021-03-01 2021-10-21 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) Ciprofloxacin derivative with antibacterial activity against antibiotic-resistant strains of microorganisms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4123536A (en) * 1977-12-14 1978-10-31 Warner-Lambert Company Dialkyl ({[3-(alkoxycarbonyl)-1,4-dihydro-4-oxo-8-quinolinyl]amino}methylene)propanedioates
DE3705621C2 (en) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclic substituted quinolonecarboxylic acid derivatives
JPS62215572A (en) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd Quinolone carboxylic acid derivative
US5047538A (en) * 1990-04-12 1991-09-10 Warner-Lambert Company Quinolinecarboxylic acid antibacterial agents

Also Published As

Publication number Publication date
DK0523512T3 (en) 1997-06-30
SK279221B6 (en) 1998-08-05
EP0523512A1 (en) 1993-01-20
CZ282037B6 (en) 1997-04-16
TW201309B (en) 1993-03-01
AU1966392A (en) 1993-01-21
PL295331A1 (en) 1993-07-12
ES2097835T3 (en) 1997-04-16
FI923268A (en) 1993-01-20
IL102520A (en) 1997-07-13
DE59207880D1 (en) 1997-02-27
HU9202349D0 (en) 1992-10-28
SK219192A3 (en) 1998-08-05
AU658901B2 (en) 1995-05-04
EP0523512B1 (en) 1997-01-15
KR930002320A (en) 1993-02-22
HU219910B (en) 2001-09-28
CZ219192A3 (en) 1993-02-17
IE922348A1 (en) 1993-01-27
JP3174405B2 (en) 2001-06-11
GR3022305T3 (en) 1997-04-30
NO922639D0 (en) 1992-07-03
FI923268A0 (en) 1992-07-16
CA2073993A1 (en) 1993-01-20
PL171910B1 (en) 1997-06-30
KR100240608B1 (en) 2000-03-02
JPH05262738A (en) 1993-10-12
HUT61741A (en) 1993-03-01
FI103043B1 (en) 1999-04-15
RU2077533C1 (en) 1997-04-20
NO922639L (en) 1993-01-20
MX9204110A (en) 1993-08-01
DE4123918A1 (en) 1993-01-21
NO302886B1 (en) 1998-05-04
ATE147733T1 (en) 1997-02-15
FI103043B (en) 1999-04-15
IE80557B1 (en) 1998-09-23
IL102520A0 (en) 1993-01-14

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