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ZA915905B - Cyclopentane derivatives,process for their production and their pharmaceutical use - Google Patents

Cyclopentane derivatives,process for their production and their pharmaceutical use

Info

Publication number
ZA915905B
ZA915905B ZA915905A ZA915905A ZA915905B ZA 915905 B ZA915905 B ZA 915905B ZA 915905 A ZA915905 A ZA 915905A ZA 915905 A ZA915905 A ZA 915905A ZA 915905 B ZA915905 B ZA 915905B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical use
production
cyclopentane derivatives
formula
cyclopentane
Prior art date
Application number
ZA915905A
Inventor
Ulrich Klar
Klar Ulrich
Hartmut Rehwinkel
Rehwinkel Hartmut
Helmut Vorbruggen
Vorbruggen Helmut
Karl-Heinz Thierauch
Thierauch Karl-Heinz
Peter Verhallen
Verhallen Peter
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA915905B publication Critical patent/ZA915905B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to cyclopentane derivatives of formula (I) and their salts with physiologically tolerables bases and the $g(a), $g(b) or $g(g)-cyclodextrin clathrates and the liposome-encapsulated compounds of formula (I), a process for producing them and their pharmaceutical use.
ZA915905A 1990-07-27 1991-07-26 Cyclopentane derivatives,process for their production and their pharmaceutical use ZA915905B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4024347A DE4024347A1 (en) 1990-07-27 1990-07-27 CYCLOPENTANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL USE

Publications (1)

Publication Number Publication Date
ZA915905B true ZA915905B (en) 1992-04-29

Family

ID=6411402

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA915905A ZA915905B (en) 1990-07-27 1991-07-26 Cyclopentane derivatives,process for their production and their pharmaceutical use

Country Status (13)

Country Link
EP (1) EP0541594B1 (en)
JP (1) JPH06502390A (en)
AT (1) ATE122036T1 (en)
AU (1) AU8221291A (en)
CA (1) CA2088161A1 (en)
DE (3) DE4024347A1 (en)
DK (1) DK0541594T3 (en)
ES (1) ES2074721T3 (en)
IE (1) IE67507B1 (en)
IL (1) IL98970A0 (en)
PT (1) PT98464B (en)
WO (1) WO1992002495A1 (en)
ZA (1) ZA915905B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4036140A1 (en) * 1990-11-09 1992-05-14 Schering Ag 9-HALOGEN-11SS-HYDROXY-PROSTAGLANDIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
AU687906B2 (en) * 1993-12-15 1998-03-05 Alcon Laboratories, Inc. Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
NZ503738A (en) * 1997-09-09 2001-05-25 Procter & Gamble Aromatic C16-20-substituted tetrahydro prostaglandin F analogues useful as FP agonists
NZ503736A (en) * 1997-09-09 2002-06-28 Procter & Gamble Aromatic C16-C20-substituted tetrahydro prostaglandins useful as FP agonists
US5977173A (en) * 1997-09-09 1999-11-02 Wos; John August Aromatic C16 -C20 -substituted tetrahydro prostaglandins useful as FP agonists
US6242493B1 (en) 1998-03-13 2001-06-05 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
WO1999047497A2 (en) * 1998-03-13 1999-09-23 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
DE60015508T2 (en) 1999-03-05 2005-04-21 Univ Durham C-16 UNAUDITED FP-SELECTIVE PROSTAGLANDIN ANALOGUE
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US7323591B2 (en) * 2006-01-10 2008-01-29 Allergan, Inc. Substituted cyclopentanes or cyclopentanones as therapeutic agents
US8592413B2 (en) 2008-05-15 2013-11-26 Allergan, Inc. Therapeutic substituted cyclopentanes
CN102336754B (en) * 2010-07-15 2017-04-12 浙江奥翔药业股份有限公司 Method for synthesizing entecavir and intermediate compound thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1431561A (en) * 1973-01-31 1976-04-07 Ici Ltd Cyclopentane derivatives
IT1053781B (en) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia OMEGA NOR CICLOALCIL 13.14 DEIDRO PROSTAGLANDINE
FR2349328A1 (en) * 1976-04-30 1977-11-25 Roussel Uclaf (11)-Deoxy-prostaglandin analogues - for use as hypotensives, smooth-muscle contractants and luteolytic agents
DE3126924A1 (en) * 1981-07-03 1983-01-20 Schering Ag, 1000 Berlin Und 4619 Bergkamen 9-FLUOR PROSTAGLAND DERIVATIVES, METHOD FOR THE PRODUCTION AND USE AS A MEDICINAL PRODUCT
DE3325175A1 (en) * 1983-07-08 1985-01-17 Schering AG, 1000 Berlin und 4709 Bergkamen 11-HALOGEN PROSTANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
DE3510978A1 (en) * 1985-03-22 1986-09-25 Schering AG, Berlin und Bergkamen, 1000 Berlin NEW 9-HALOGEN PROSTAGLANDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
ES2054860T5 (en) * 1987-07-17 2003-11-01 Schering Ag DERIVATIVES OF 9-HALOGEN- (Z) -PROSTAGLANDINAS, PROCEDURE FOR ITS PREPARATION AND ITS USE AS MEDICATIONS.
DE3923797A1 (en) * 1989-07-14 1991-01-24 Schering Ag 9-FLUOR-PROSTAGLANDIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL USE

Also Published As

Publication number Publication date
EP0541594B1 (en) 1995-05-03
DE4024347A1 (en) 1992-01-30
JPH06502390A (en) 1994-03-17
DE4191848D2 (en) 1993-10-07
IE67507B1 (en) 1996-04-03
CA2088161A1 (en) 1992-01-28
PT98464B (en) 1997-10-31
ATE122036T1 (en) 1995-05-15
IE912654A1 (en) 1992-01-29
WO1992002495A1 (en) 1992-02-20
AU8221291A (en) 1992-03-02
EP0541594A1 (en) 1993-05-19
IL98970A0 (en) 1992-07-15
DK0541594T3 (en) 1995-10-02
PT98464A (en) 1992-05-29
DE59105400D1 (en) 1995-06-08
ES2074721T3 (en) 1995-09-16

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