ZA915905B - Cyclopentane derivatives,process for their production and their pharmaceutical use - Google Patents
Cyclopentane derivatives,process for their production and their pharmaceutical useInfo
- Publication number
- ZA915905B ZA915905B ZA915905A ZA915905A ZA915905B ZA 915905 B ZA915905 B ZA 915905B ZA 915905 A ZA915905 A ZA 915905A ZA 915905 A ZA915905 A ZA 915905A ZA 915905 B ZA915905 B ZA 915905B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceutical use
- production
- cyclopentane derivatives
- formula
- cyclopentane
- Prior art date
Links
- 125000001511 cyclopentyl group Chemical class [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 title abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to cyclopentane derivatives of formula (I) and their salts with physiologically tolerables bases and the $g(a), $g(b) or $g(g)-cyclodextrin clathrates and the liposome-encapsulated compounds of formula (I), a process for producing them and their pharmaceutical use.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4024347A DE4024347A1 (en) | 1990-07-27 | 1990-07-27 | CYCLOPENTANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL USE |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA915905B true ZA915905B (en) | 1992-04-29 |
Family
ID=6411402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA915905A ZA915905B (en) | 1990-07-27 | 1991-07-26 | Cyclopentane derivatives,process for their production and their pharmaceutical use |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0541594B1 (en) |
JP (1) | JPH06502390A (en) |
AT (1) | ATE122036T1 (en) |
AU (1) | AU8221291A (en) |
CA (1) | CA2088161A1 (en) |
DE (3) | DE4024347A1 (en) |
DK (1) | DK0541594T3 (en) |
ES (1) | ES2074721T3 (en) |
IE (1) | IE67507B1 (en) |
IL (1) | IL98970A0 (en) |
PT (1) | PT98464B (en) |
WO (1) | WO1992002495A1 (en) |
ZA (1) | ZA915905B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4036140A1 (en) * | 1990-11-09 | 1992-05-14 | Schering Ag | 9-HALOGEN-11SS-HYDROXY-PROSTAGLANDIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS |
AU687906B2 (en) * | 1993-12-15 | 1998-03-05 | Alcon Laboratories, Inc. | Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension |
NZ503738A (en) * | 1997-09-09 | 2001-05-25 | Procter & Gamble | Aromatic C16-20-substituted tetrahydro prostaglandin F analogues useful as FP agonists |
NZ503736A (en) * | 1997-09-09 | 2002-06-28 | Procter & Gamble | Aromatic C16-C20-substituted tetrahydro prostaglandins useful as FP agonists |
US5977173A (en) * | 1997-09-09 | 1999-11-02 | Wos; John August | Aromatic C16 -C20 -substituted tetrahydro prostaglandins useful as FP agonists |
US6242493B1 (en) | 1998-03-13 | 2001-06-05 | Merck Frosst Canada & Co. | Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment |
WO1999047497A2 (en) * | 1998-03-13 | 1999-09-23 | Merck Frosst Canada & Co. | Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment |
DE60015508T2 (en) | 1999-03-05 | 2005-04-21 | Univ Durham | C-16 UNAUDITED FP-SELECTIVE PROSTAGLANDIN ANALOGUE |
US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
US7323591B2 (en) * | 2006-01-10 | 2008-01-29 | Allergan, Inc. | Substituted cyclopentanes or cyclopentanones as therapeutic agents |
US8592413B2 (en) | 2008-05-15 | 2013-11-26 | Allergan, Inc. | Therapeutic substituted cyclopentanes |
CN102336754B (en) * | 2010-07-15 | 2017-04-12 | 浙江奥翔药业股份有限公司 | Method for synthesizing entecavir and intermediate compound thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1431561A (en) * | 1973-01-31 | 1976-04-07 | Ici Ltd | Cyclopentane derivatives |
IT1053781B (en) * | 1974-09-25 | 1981-10-10 | Erba C S P A Ora Farmitalia | OMEGA NOR CICLOALCIL 13.14 DEIDRO PROSTAGLANDINE |
FR2349328A1 (en) * | 1976-04-30 | 1977-11-25 | Roussel Uclaf | (11)-Deoxy-prostaglandin analogues - for use as hypotensives, smooth-muscle contractants and luteolytic agents |
DE3126924A1 (en) * | 1981-07-03 | 1983-01-20 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 9-FLUOR PROSTAGLAND DERIVATIVES, METHOD FOR THE PRODUCTION AND USE AS A MEDICINAL PRODUCT |
DE3325175A1 (en) * | 1983-07-08 | 1985-01-17 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11-HALOGEN PROSTANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS |
DE3510978A1 (en) * | 1985-03-22 | 1986-09-25 | Schering AG, Berlin und Bergkamen, 1000 Berlin | NEW 9-HALOGEN PROSTAGLANDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS |
ES2054860T5 (en) * | 1987-07-17 | 2003-11-01 | Schering Ag | DERIVATIVES OF 9-HALOGEN- (Z) -PROSTAGLANDINAS, PROCEDURE FOR ITS PREPARATION AND ITS USE AS MEDICATIONS. |
DE3923797A1 (en) * | 1989-07-14 | 1991-01-24 | Schering Ag | 9-FLUOR-PROSTAGLANDIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL USE |
-
1990
- 1990-07-27 DE DE4024347A patent/DE4024347A1/en not_active Withdrawn
-
1991
- 1991-07-22 DK DK91912997.3T patent/DK0541594T3/en active
- 1991-07-22 EP EP91912997A patent/EP0541594B1/en not_active Expired - Lifetime
- 1991-07-22 JP JP3512332A patent/JPH06502390A/en active Pending
- 1991-07-22 CA CA002088161A patent/CA2088161A1/en not_active Abandoned
- 1991-07-22 DE DEDE9100609T patent/DE4191848D2/en not_active Expired - Fee Related
- 1991-07-22 ES ES91912997T patent/ES2074721T3/en not_active Expired - Lifetime
- 1991-07-22 AU AU82212/91A patent/AU8221291A/en not_active Abandoned
- 1991-07-22 AT AT91912997T patent/ATE122036T1/en not_active IP Right Cessation
- 1991-07-22 WO PCT/DE1991/000604 patent/WO1992002495A1/en active IP Right Grant
- 1991-07-22 DE DE59105400T patent/DE59105400D1/en not_active Expired - Lifetime
- 1991-07-26 PT PT98464A patent/PT98464B/en not_active IP Right Cessation
- 1991-07-26 IL IL98970A patent/IL98970A0/en unknown
- 1991-07-26 ZA ZA915905A patent/ZA915905B/en unknown
- 1991-07-29 IE IE265491A patent/IE67507B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0541594B1 (en) | 1995-05-03 |
DE4024347A1 (en) | 1992-01-30 |
JPH06502390A (en) | 1994-03-17 |
DE4191848D2 (en) | 1993-10-07 |
IE67507B1 (en) | 1996-04-03 |
CA2088161A1 (en) | 1992-01-28 |
PT98464B (en) | 1997-10-31 |
ATE122036T1 (en) | 1995-05-15 |
IE912654A1 (en) | 1992-01-29 |
WO1992002495A1 (en) | 1992-02-20 |
AU8221291A (en) | 1992-03-02 |
EP0541594A1 (en) | 1993-05-19 |
IL98970A0 (en) | 1992-07-15 |
DK0541594T3 (en) | 1995-10-02 |
PT98464A (en) | 1992-05-29 |
DE59105400D1 (en) | 1995-06-08 |
ES2074721T3 (en) | 1995-09-16 |
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