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ZA906539B - Method and device for administering dexmedetomidine transdermally - Google Patents

Method and device for administering dexmedetomidine transdermally

Info

Publication number
ZA906539B
ZA906539B ZA906539A ZA906539A ZA906539B ZA 906539 B ZA906539 B ZA 906539B ZA 906539 A ZA906539 A ZA 906539A ZA 906539 A ZA906539 A ZA 906539A ZA 906539 B ZA906539 B ZA 906539B
Authority
ZA
South Africa
Prior art keywords
administering
dexmedetomidine
adhesive layer
therapeutic system
transdermally
Prior art date
Application number
ZA906539A
Other languages
English (en)
Inventor
Kenneth J Colley
J Colley Kenneth
Donald R Wilson
R Wilson Donald
Gary W Cleary
W Cleary Gary
Risto Lammintausta
Lammintausta Risto
Harry Jalonen
Jalonen Harry
Original Assignee
Cygnus Research Corp
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cygnus Research Corp, Orion Corp filed Critical Cygnus Research Corp
Publication of ZA906539B publication Critical patent/ZA906539B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA906539A 1989-08-18 1990-08-17 Method and device for administering dexmedetomidine transdermally ZA906539B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/395,717 US5124157A (en) 1989-08-18 1989-08-18 Method and device for administering dexmedetomidine transdermally

Publications (1)

Publication Number Publication Date
ZA906539B true ZA906539B (en) 1991-06-26

Family

ID=23564195

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA906539A ZA906539B (en) 1989-08-18 1990-08-17 Method and device for administering dexmedetomidine transdermally

Country Status (25)

Country Link
US (1) US5124157A (zh)
EP (1) EP0413487B1 (zh)
JP (1) JP3043064B2 (zh)
CN (1) CN1035922C (zh)
AT (1) ATE122899T1 (zh)
AU (1) AU639015B2 (zh)
BG (1) BG95935A (zh)
CA (1) CA2064687C (zh)
DD (1) DD297066A5 (zh)
DE (1) DE69019628T2 (zh)
DK (1) DK0413487T3 (zh)
ES (1) ES2072397T3 (zh)
FI (1) FI100857B (zh)
HU (1) HUT64223A (zh)
IE (1) IE67127B1 (zh)
LT (1) LT3753B (zh)
LV (1) LV10685B (zh)
NO (1) NO300408B1 (zh)
NZ (1) NZ234749A (zh)
PL (1) PL165023B1 (zh)
PT (1) PT95002B (zh)
RU (1) RU2098083C1 (zh)
UA (1) UA26988C2 (zh)
WO (1) WO1991002505A1 (zh)
ZA (1) ZA906539B (zh)

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GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
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US6716867B1 (en) 1998-04-01 2004-04-06 Orion Corporation Use of dexmedetomidine for ICU sedation
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US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
DE10234673B4 (de) * 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US8246980B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
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IL152574A (en) 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
US7662404B2 (en) 2002-10-31 2010-02-16 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides
US8133505B2 (en) 2002-10-31 2012-03-13 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
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DE10261696A1 (de) * 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
DE102006054733A1 (de) * 2006-11-21 2008-05-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
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BRPI1010567A2 (pt) * 2009-05-15 2016-03-15 Recro Pharma Inc composições sublinguais de dexmedetomidina e métodos de uso e aparelho que os emprega
CA2786598A1 (en) * 2010-01-08 2011-07-14 Recro Pharma, Inc. Topical transdermal dexmedetomidine compositions and methods of use thereof
US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
JP6268100B2 (ja) 2011-12-11 2018-01-24 レクロ・ファーマ，インコーポレーテッド 鼻腔内デクスメデトミジン組成物およびその使用方法
US8242158B1 (en) 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
WO2013173317A1 (en) * 2012-05-14 2013-11-21 Prospire, Llc TREATMENT OF OBSTRUCTIVE SLEEP APNEA WITH α2-ADRENERGIC RECEPTOR AGONISTS
CA2924188C (en) * 2013-10-07 2018-12-18 Teikoku Pharma Usa, Inc. Methods and compositions for managing pain comprising dexmedetomidine transdermal compositions
BR112016006848A2 (pt) * 2013-10-07 2017-08-01 Teikoku Pharma Usa Inc métodos e composições para distribuição transdérmica de uma quantidade não sedativa de dexmedetomidina
FI3054934T3 (fi) * 2013-10-07 2024-07-19 Teikoku Pharma Usa Inc Menetelmät ja koostumukset vieroitusoireyhtymien hoitoon käyttäen ei-sedatiivisia transdermaalisia deksmedetomidiinikoostumuksia
CA2924231C (en) * 2013-10-07 2018-04-03 Teikoku Pharma Usa, Inc. Dexmedetomidine transdermal delivery devices and methods for using the same
TWI709417B (zh) * 2013-10-07 2020-11-11 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
TW201609200A (zh) * 2013-12-18 2016-03-16 丸石製藥股份有限公司 含水型貼劑
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TWI764951B (zh) * 2016-10-31 2022-05-21 美商帝國製藥美國股份有限公司 用於處理疼痛之右美托咪啶經皮遞送裝置
CN110114069B (zh) * 2016-12-26 2022-03-04 久光制药株式会社 微针装置
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Also Published As

Publication number Publication date
DK0413487T3 (da) 1995-07-17
DE69019628T2 (de) 1995-09-28
PL286525A1 (en) 1991-05-20
DD297066A5 (de) 1992-01-02
JPH05503916A (ja) 1993-06-24
IE902993A1 (en) 1991-02-27
CA2064687A1 (en) 1991-02-19
AU6183490A (en) 1991-04-03
NO300408B1 (no) 1997-05-26
US5124157A (en) 1992-06-23
HUT64223A (en) 1993-12-28
WO1991002505A1 (en) 1991-03-07
LV10685B (en) 1995-12-20
LTIP1773A (en) 1995-07-25
DE69019628D1 (de) 1995-06-29
FI100857B (fi) 1998-03-13
RU2098083C1 (ru) 1997-12-10
PL165023B1 (pl) 1994-11-30
PT95002A (pt) 1992-02-28
EP0413487B1 (en) 1995-05-24
ES2072397T3 (es) 1995-07-16
CA2064687C (en) 1998-04-21
HU9200517D0 (en) 1992-05-28
AU639015B2 (en) 1993-07-15
PT95002B (pt) 1997-10-31
CN1035922C (zh) 1997-09-24
NO920521D0 (no) 1992-02-10
ATE122899T1 (de) 1995-06-15
NO920521L (no) 1992-02-10
LT3753B (en) 1996-03-25
FI920576A0 (fi) 1992-02-11
IE67127B1 (en) 1996-03-06
JP3043064B2 (ja) 2000-05-22
NZ234749A (en) 1992-03-26
EP0413487A1 (en) 1991-02-20
UA26988C2 (uk) 2000-02-28
BG95935A (bg) 1993-12-24
CN1049450A (zh) 1991-02-27
LV10685A (lv) 1995-06-20

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