ZA906302B - Novel 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives,pharmaceutical compositions containing them and process for preparing same - Google Patents

Novel 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives,pharmaceutical compositions containing them and process for preparing same

Info

Publication number: ZA906302B
Authority: ZA; South Africa
Prior art keywords: group; alkyl; halogen atoms; oxa; oxo
Prior art date: 1989-08-10

Application number

ZA906302A

Other languages

English (en)

Inventor

Edit Toth

Toth Edit

Jozsef Toerley

Toerley Jozsef

Laszlo Szporny

Szporny Laszlo

Bela Kiss

Kiss Bela

Egon Karpati

Karpati Egon

Eva Palosi

Palosi Eva

Dora Groo

Groo Dora

Istvan Laszlovszky

Laszlovszky Istvan

Zsolt Szombathelyi

Szombathelyi Zsolt

Adam Sarkadi

Sarkadi Adam

Aniko Gere

Gere Aniko

Katalin Csomor

Csomor Katalin

Mihaly Bodo

Bodo Mihaly

Judit Laszy

Laszy Judit

Zsolt Szentimay

Szentimay Zsolt

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-10

Filing date

1990-08-09

Publication date

1991-06-26

1990-08-09 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1991-06-26 Publication of ZA906302B publication Critical patent/ZA906302B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Cardiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Hydrogenated Pyridines (AREA)

ZA906302A 1989-08-10 1990-08-09 Novel 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives,pharmaceutical compositions containing them and process for preparing same ZA906302B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU894095A HU204530B (en)	1989-08-10	1989-08-10	Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
SG96294A SG96294G (en)	1989-08-10	1994-07-16	1-oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number	Publication Date
ZA906302B true ZA906302B (en)	1991-06-26

Family

ID=26317733

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA906302A ZA906302B (en)	1989-08-10	1990-08-09	Novel 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives,pharmaceutical compositions containing them and process for preparing same

Country Status (23)

Country	Link
US (1)	US5118687A (hu)
EP (1)	EP0414421B1 (hu)
JP (1)	JPH0749431B2 (hu)
KR (1)	KR940006635B1 (hu)
AT (1)	ATE103920T1 (hu)
AU (1)	AU622039B2 (hu)
BG (1)	BG60436B2 (hu)
DD (1)	DD299429A5 (hu)
DE (1)	DE69007904T2 (hu)
DK (1)	DK0414421T3 (hu)
ES (1)	ES2052180T3 (hu)
FI (1)	FI93455C (hu)
HK (1)	HK145994A (hu)
HR (1)	HRP920778A2 (hu)
HU (2)	HU204530B (hu)
IE (1)	IE64911B1 (hu)
IL (1)	IL95320A (hu)
NO (1)	NO177962C (hu)
NZ (1)	NZ234848A (hu)
PL (3)	PL163593B1 (hu)
SG (1)	SG96294G (hu)
SI (1)	SI9011538A (hu)
ZA (1)	ZA906302B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU150489A (sh) *	1989-08-10	1992-12-21	W.L. Gore & Co. Gmbh.	Uređaj za ispitivanje odevnih predmeta na nepromočivost
WO2001028602A1 (en) *	1999-10-15	2001-04-26	Genetics Institute, Inc.	Formulations of hyaluronic acid for delivery of osteogenic proteins
KR20020091462A (ko) *	2001-05-30	2002-12-06	삼성광주전자 주식회사	원료 굳음 방지기능을 갖는 자동판매기 및 그 제어방법
GB201416346D0 (en) *	2014-09-16	2014-10-29	Shire Internat Gmbh	Spirocyclic derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR96352E (fr) *	1967-12-29	1972-06-16	Science Union & Cie	Nouveaux dérives du spiro (4,5) decane et leur procédé de préparation.
BE790675A (fr) *	1971-10-29	1973-04-27	Science Union & Cie	Nouveaux derives de l'oxa-1 diaza-3,8 spiro (4,5) decane
EP0189370A3 (de) *	1985-01-16	1988-01-27	Sandoz Ag	Spiro-dioxolane, -dithiolane und -oxothiolane
KR940003491B1 (ko) *	1989-08-10	1994-04-23	리히터 게데온 베기에스제티 기아르 알.티	4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
HU204529B (en) *	1989-08-10	1992-01-28	Richter Gedeon Vegyeszet	Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them

1989
- 1989-08-10 HU HU894095A patent/HU204530B/hu not_active IP Right Cessation
1990
- 1990-08-09 JP JP2209358A patent/JPH0749431B2/ja not_active Expired - Lifetime
- 1990-08-09 AT AT90308784T patent/ATE103920T1/de not_active IP Right Cessation
- 1990-08-09 DK DK90308784.9T patent/DK0414421T3/da active
- 1990-08-09 SI SI9011538A patent/SI9011538A/sl unknown
- 1990-08-09 KR KR1019900012256A patent/KR940006635B1/ko not_active IP Right Cessation
- 1990-08-09 DD DD90343361A patent/DD299429A5/de not_active IP Right Cessation
- 1990-08-09 EP EP90308784A patent/EP0414421B1/en not_active Expired - Lifetime
- 1990-08-09 ZA ZA906302A patent/ZA906302B/xx unknown
- 1990-08-09 NZ NZ234848A patent/NZ234848A/en unknown
- 1990-08-09 IL IL9532090A patent/IL95320A/en not_active IP Right Cessation
- 1990-08-09 DE DE69007904T patent/DE69007904T2/de not_active Expired - Fee Related
- 1990-08-09 IE IE288490A patent/IE64911B1/en not_active IP Right Cessation
- 1990-08-09 NO NO903512A patent/NO177962C/no unknown
- 1990-08-09 ES ES90308784T patent/ES2052180T3/es not_active Expired - Lifetime
- 1990-08-09 AU AU60807/90A patent/AU622039B2/en not_active Ceased
- 1990-08-10 PL PL90291702A patent/PL163593B1/pl unknown
- 1990-08-10 PL PL90286440A patent/PL163370B1/pl unknown
- 1990-08-10 PL PL90291701A patent/PL163431B1/pl unknown
- 1990-08-10 FI FI903972A patent/FI93455C/fi not_active IP Right Cessation
- 1990-08-10 US US07/566,275 patent/US5118687A/en not_active Expired - Fee Related
1992
- 1992-10-01 HR HRP-1538/90A patent/HRP920778A2/hr not_active Application Discontinuation
1993
- 1993-12-02 BG BG098261A patent/BG60436B2/bg unknown
1994
- 1994-07-16 SG SG96294A patent/SG96294G/en unknown
- 1994-10-12 HU HU94P/P00036P patent/HU210072A9/hu unknown
- 1994-12-22 HK HK145994A patent/HK145994A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU210072A9 (en)	1995-02-28
JPH0377884A (ja)	1991-04-03
IE64911B1 (en)	1995-09-20
NO177962B (no)	1995-09-18
HK145994A (en)	1994-12-30
NO903512D0 (no)	1990-08-09
IE902884A1 (en)	1991-02-27
HUT55786A (en)	1991-06-28
SI9011538A (sl)	1998-08-31
PL291702A1 (en)	1992-05-04
ATE103920T1 (de)	1994-04-15
IL95320A0 (en)	1991-06-30
NO903512L (no)	1991-02-11
DK0414421T3 (da)	1994-05-16
ES2052180T3 (es)	1994-07-01
AU622039B2 (en)	1992-03-26
HU204530B (en)	1992-01-28
NO177962C (no)	1995-12-27
DD299429A5 (de)	1992-04-16
PL163593B1 (en)	1994-04-29
FI903972A0 (fi)	1990-08-10
JPH0749431B2 (ja)	1995-05-31
DE69007904T2 (de)	1994-07-21
BG60436B2 (bg)	1995-03-31
PL163370B1 (pl)	1994-03-31
PL163431B1 (pl)	1994-03-31
KR940006635B1 (ko)	1994-07-23
DE69007904D1 (de)	1994-05-11
EP0414421A3 (en)	1991-07-24
AU6080790A (en)	1991-02-14
US5118687A (en)	1992-06-02
IL95320A (en)	1994-01-25
NZ234848A (en)	1992-03-26
EP0414421A2 (en)	1991-02-27
PL291701A1 (en)	1992-05-04
EP0414421B1 (en)	1994-04-06
FI93455C (fi)	1995-04-10
SG96294G (en)	1994-10-28
PL286440A1 (en)	1992-01-27
HRP920778A2 (en)	1998-02-28
FI93455B (fi)	1994-12-30
KR910004632A (ko)	1991-03-29

Publication	Publication Date	Title
AU623545B2 (en)	1992-05-14	Novel 2-oxo-1-oxa-8-azaspiro(4,5)decane derivatives, pharmaceutical compositions containing them and process for preparing the same
ATE63746T1 (de)	1991-06-15	Thiophenderivat und verfahren zur herstellung.
AU622039B2 (en)	1992-03-26	Novel 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives, pharmaceutical compositions containing them and process for preparing the same
AU624261B2 (en)	1992-06-04	Novel 4,4-disubstituted piperidine derivatives, pharmaceutical compositions containing them and process for preparing the same
HUT58269A (en)	1992-02-28	Process for producing aralkyl-amine derivatives and pharmaceutical compositions containing them as active components
AU621239B2 (en)	1992-03-05	Novel 2-oxo-1-oxa-8-azaspiro(4,5)decane derivatives, pharmaceutical compositions containing them and process for preparing the same
HUT57221A (en)	1991-11-28	Process for producing pyrrolo(2,1-b)thiazol derivatives and pahrmaceutical compositions contiaining them as active components