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ZA895840B - N-2,3-butadienyl tri-and tetraaminoalkane derivatives - Google Patents

N-2,3-butadienyl tri-and tetraaminoalkane derivatives

Info

Publication number
ZA895840B
ZA895840B ZA895840A ZA895840A ZA895840B ZA 895840 B ZA895840 B ZA 895840B ZA 895840 A ZA895840 A ZA 895840A ZA 895840 A ZA895840 A ZA 895840A ZA 895840 B ZA895840 B ZA 895840B
Authority
ZA
South Africa
Prior art keywords
butadienyl
tri
tetraaminoalkane
derivatives
polyamines
Prior art date
Application number
ZA895840A
Other languages
English (en)
Inventor
Philippe Bey
Bey Philippe
David Martin Stemerick
Martin Stemerick David
Michael Louis Edwards
Louis Edwards Michael
Alan Joseph Bitonti
Joseph Bitonti Alan
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA895840B publication Critical patent/ZA895840B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/21Monoamines
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02Amines; Quaternary ammonium compounds
    • A01N33/04Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Environmental Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA895840A 1988-08-04 1989-07-31 N-2,3-butadienyl tri-and tetraaminoalkane derivatives ZA895840B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/228,620 US4935449A (en) 1988-08-04 1988-08-04 N-2,3-butadienyl tri- and tetraaminoalkane derivatives

Publications (1)

Publication Number Publication Date
ZA895840B true ZA895840B (en) 1990-04-25

Family

ID=22857945

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA895840A ZA895840B (en) 1988-08-04 1989-07-31 N-2,3-butadienyl tri-and tetraaminoalkane derivatives

Country Status (19)

Country Link
US (1) US4935449A (zh)
EP (1) EP0353752B1 (zh)
JP (1) JP2722255B2 (zh)
KR (1) KR0144155B1 (zh)
CN (1) CN1039800A (zh)
AT (1) ATE99669T1 (zh)
AU (1) AU617502B2 (zh)
CA (1) CA1321603C (zh)
DE (1) DE68912020T2 (zh)
DK (1) DK381189A (zh)
ES (1) ES2061826T3 (zh)
FI (1) FI893681A (zh)
HU (1) HU207833B (zh)
IL (1) IL91184A0 (zh)
NO (1) NO172043C (zh)
NZ (1) NZ230155A (zh)
PH (1) PH27214A (zh)
PT (1) PT91365A (zh)
ZA (1) ZA895840B (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9111794D0 (en) * 1991-05-31 1991-07-24 Robins David J Antifungal compounds
CN1121707A (zh) * 1993-12-27 1996-05-01 西巴-盖尔基股份公司 用作抗癌剂和抗原生动物剂的不饱和氨基化合物
US5677350A (en) * 1995-06-07 1997-10-14 Wisconsin Alumni Research Foundation Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
EP1698629A3 (en) 1999-04-30 2006-11-29 Cellgate, Inc. Polyamines and their use in therapy
US6482943B1 (en) 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
WO2002038105A2 (en) * 2000-11-08 2002-05-16 Slil Biomedical Corporation Novel polyamine analog-amino acid conjugates useful as anticancer agents
WO2000066175A2 (en) * 1999-04-30 2000-11-09 Slil Biomedical Corporation Conjugates as therapies for cancer and prostate diseases
US7045550B2 (en) * 2001-08-07 2006-05-16 Wisconsin Alumni Research Foundation Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
US7211602B2 (en) * 2001-11-16 2007-05-01 Als Therapy Development Foundation, Inc. Treatment of neurodegenerative disorders through the modulation of the polyamine pathway
AU2002364539A1 (en) 2001-12-07 2003-06-23 Cellgate, Inc. Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
EP1478618A1 (en) * 2002-02-07 2004-11-24 Wisconsin Alumni Research Foundation Polyamine compounds and compositions for use in conjunction with cancer therapy
EP3971178A1 (en) 2012-03-07 2022-03-23 The McLean Hospital Corporation Aminoquinoline derivatives and uses thereof
CN102924390B (zh) * 2012-09-07 2014-12-31 苏州康润医药有限公司 1,5-二氮杂环辛烷-1-甲酸叔丁酯的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3462686D1 (de) * 1983-12-06 1987-04-23 Merrell Dow Pharma N-2,3-butadienyl-1,4-butanediamine derivatives
US4551550A (en) * 1983-12-06 1985-11-05 Merrell Dow Pharmaceuticals Inc. N-2,3-Butadienyl-1,4-butanediamine derivatives
AU602186B2 (en) * 1987-02-03 1990-10-04 Merrell Dow Pharmaceuticals Inc. Novel polyamine derivatives
US5120764A (en) * 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase

Also Published As

Publication number Publication date
NO172043C (no) 1993-06-02
AU617502B2 (en) 1991-11-28
EP0353752B1 (en) 1994-01-05
US4935449A (en) 1990-06-19
IL91184A0 (en) 1990-03-19
DE68912020D1 (de) 1994-02-17
PH27214A (en) 1993-05-04
CA1321603C (en) 1993-08-24
DK381189D0 (da) 1989-08-03
FI893681A0 (fi) 1989-08-03
NO893135D0 (no) 1989-08-03
DK381189A (da) 1990-02-05
KR900003105A (ko) 1990-03-23
NZ230155A (en) 1991-08-27
ATE99669T1 (de) 1994-01-15
HU207833B (en) 1993-06-28
HUT58037A (en) 1992-01-28
KR0144155B1 (ko) 1998-07-15
DE68912020T2 (de) 1994-04-28
EP0353752A1 (en) 1990-02-07
PT91365A (pt) 1990-03-08
JPH0283357A (ja) 1990-03-23
NO172043B (no) 1993-02-22
NO893135L (no) 1990-02-05
ES2061826T3 (es) 1994-12-16
CN1039800A (zh) 1990-02-21
AU3927189A (en) 1990-02-08
FI893681A (fi) 1990-02-05
JP2722255B2 (ja) 1998-03-04

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