[go: up one dir, main page]

ZA855696B - Method for the production of 2'-deoxyadenosine compounds - Google Patents

Method for the production of 2'-deoxyadenosine compounds

Info

Publication number
ZA855696B
ZA855696B ZA855696A ZA855696A ZA855696B ZA 855696 B ZA855696 B ZA 855696B ZA 855696 A ZA855696 A ZA 855696A ZA 855696 A ZA855696 A ZA 855696A ZA 855696 B ZA855696 B ZA 855696B
Authority
ZA
South Africa
Prior art keywords
deoxyadenosine
production
compounds
deoxyadenosine compounds
dichloropurine
Prior art date
Application number
ZA855696A
Other languages
English (en)
Inventor
Roland Kenith Robins
Ganapathi Ramakrishna Revankar
Original Assignee
Univ Brigham Young
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Brigham Young filed Critical Univ Brigham Young
Publication of ZA855696B publication Critical patent/ZA855696B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA855696A 1984-08-06 1985-07-29 Method for the production of 2'-deoxyadenosine compounds ZA855696B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63819284A 1984-08-06 1984-08-06

Publications (1)

Publication Number Publication Date
ZA855696B true ZA855696B (en) 1986-04-30

Family

ID=24559020

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA855696A ZA855696B (en) 1984-08-06 1985-07-29 Method for the production of 2'-deoxyadenosine compounds

Country Status (9)

Country Link
EP (1) EP0173059B1 (es)
JP (2) JPS61106594A (es)
AT (1) ATE48278T1 (es)
AU (1) AU572673B2 (es)
CA (1) CA1269659A (es)
DE (1) DE3574472D1 (es)
DK (1) DK165453C (es)
ES (1) ES8606383A1 (es)
ZA (1) ZA855696B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0217199A (ja) * 1988-07-05 1990-01-22 Japan Tobacco Inc 2’−デオキシ−β−アデノシンの製造方法
JPH02160799A (ja) * 1988-12-13 1990-06-20 Yuki Gosei Kogyo Co Ltd 2′−デオキシ−β−アデノシンの製造法
US5208327A (en) * 1991-12-18 1993-05-04 Ortho Pharmaceutical Corporation Intermediates useful in a synthesis of 2-chloro-2'-deoxyadenosine
EP1556400B1 (en) * 2002-09-25 2013-05-01 Brigham Young University Method for the preparation of 2-halo-2 -deoxyadenosine compounds from 2 -deoxyguanosine
SI3332789T1 (sl) 2004-12-22 2022-08-31 Merck Serono Sa, Centre Industriel Režim zdravljenja s kladaribinom za zdravljenje multiple skleroze
CA2649810A1 (en) 2006-05-24 2007-11-29 Laboratoires Serono S.A. Cladribine regimen for treating multiple sclerosis
PL1932918T3 (pl) 2006-12-15 2010-03-31 Explora Laboratories Sa Sposób otrzymywania kladrybiny
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
MX2011006890A (es) 2008-12-23 2011-07-20 Pharmasset Inc Analogos de nucleosidos.
PT2376088T (pt) 2008-12-23 2017-05-02 Gilead Pharmasset Llc Fosforamidatos de nucleósidos de 2-amino-purina 6-osubstituída
TW201031675A (en) 2008-12-23 2010-09-01 Pharmasset Inc Synthesis of purine nucleosides
US8232387B2 (en) 2009-08-18 2012-07-31 Scinopharm Taiwan, Ltd. Process for the preparation of cladribine
EP2343074A1 (en) 2009-12-23 2011-07-13 Merck Serono S.A. Use of purine analogues for treating airway diseases
WO2011113476A2 (en) 2010-03-16 2011-09-22 Cilag Ag Method for producing 2'-deoxyadenosine compounds
CL2011000716A1 (es) 2010-03-31 2012-04-20 Gilead Pharmasset Llc Formas cristalinas 1 6 de (s)-isopropil-2-(((s)-(((2r.3r.4r.5r)-5-(2,4-dioxo-3,4-dihidropirimidin-1(2h)-il)-4-fluoro-3-hidroxi-4-metil tetrahidrofuran-2-il)metoxi)(fenoxi)fosforil)amino)propanoato; composicion y combinacion farmaceutica; y su uso para tratar una infeccion por el virus de la hepatitis c.
GB201401465D0 (en) 2014-01-29 2014-03-12 Roach Arthur H Use of cladribine for treating autoimmune inflammatory disease
EP2993177A1 (en) 2014-09-05 2016-03-09 Technische Universität Berlin A chemo-enzymatic preparation method for purine nucleosides and their deaza- and aza- analogues
GB2564717A (en) 2017-07-21 2019-01-23 Chord Therapeutics S A R L Use of cladribine for treating autoimmune neuromuscular disease
MX2020005266A (es) 2017-11-24 2020-09-18 Merck Patent Gmbh Regimen de cladribina para usarse en el tratamiento de formas progresivas de esclerosis multiple.
IL301246A (en) 2020-09-10 2023-05-01 Merck Patent Gmbh Cladribine treatment regimen
GB2601786A (en) 2020-12-10 2022-06-15 Chord Therapeutics S A R L Use of cladribine for treating immune brain disease
AU2022231384A1 (en) 2021-03-03 2023-09-14 Ares Trading S.A. Improved treatment methods using dmds for the treatment of autoimmune diseases, and biomarker for predicting and/or optimising said treatment methods
DE102023123718A1 (de) 2023-09-04 2025-03-06 CHIRACON Pharma GmbH Verfahren zur Herstellung von Nukleosiden

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3225029A (en) * 1962-03-08 1965-12-21 Yamaoka Naotaka Process for the preparation of nucleosides and products obtained thereby
US3225009A (en) * 1962-05-21 1965-12-21 Scott Paper Co Ethylene dicarboxylic esters of 1,2 alkane carbonates, polymers, and copolymers thereof
DE1795357A1 (de) * 1968-09-18 1972-01-05 Schering Ag 2-Thio-pyrimidin-nucleoside
CA1264738A (en) * 1984-12-04 1990-01-23 Eli Lilly And Company Treatment of tumors in mammals

Also Published As

Publication number Publication date
DK357585D0 (da) 1985-08-06
JPS61106594A (ja) 1986-05-24
AU572673B2 (en) 1988-05-12
ES8606383A1 (es) 1986-04-01
CA1269659A (en) 1990-05-29
DK165453C (da) 1993-04-13
ATE48278T1 (de) 1989-12-15
JPH02359B2 (es) 1990-01-08
EP0173059A3 (en) 1987-04-29
EP0173059B1 (en) 1989-11-29
DK165453B (da) 1992-11-30
DK357585A (da) 1986-02-07
EP0173059A2 (en) 1986-03-05
DE3574472D1 (de) 1990-01-04
ES545888A0 (es) 1986-04-01
AU4513885A (en) 1986-02-13
JPH0256497A (ja) 1990-02-26

Similar Documents

Publication Publication Date Title
ZA855696B (en) Method for the production of 2'-deoxyadenosine compounds
HUT37149A (en) Process for producing quinoline- and naphtiridine-carboxylic acid derivatives
HUT47303A (en) Process for producing epipodophyllotoxin-glycoside-4'-phosphate derivatives
HUT45530A (en) Process for producing 3-pyrrolidinyl-thio-1-azobicyclo (3-2-0)hept-2-en-2-carboxylic acid derivatives
UA7088A1 (uk) Спосіб одержання солі 2-(2-гідроксіетоксі)етіламіна та 3,6-діхлор-2-метоксібензойної кислоти
YU44521B (en) Process for producing bis-(2-ethylamino-4-diethyl-amino-s-triazine-6-yl)-tetrasulphide
EP0282989A3 (en) Process for producing 5'-inosinic acid
DE3369637D1 (en) Neutral topical sodium fluoride gel
HUT46021A (en) Process for producing ceph-3-eme-4-carboxylic acid derivatives
HUT45727A (en) Process for production of vinilchlorid by thermic splitting of 1,2-dichlor-ethan
FR2510092B1 (fr) Procede de production d'un fluorure de graphite
YU31285A (en) Process for producing salts of oxazaphosphorine derivatives
DE3564177D1 (en) Process for producing gluten having high solubility
HUT46023A (en) Process for producing purin-9-yl-alkoxy-methyl-phosphonic acid derivatives
HUT38912A (en) Process for producing quinolon- and naphtiridon-carboxylic acid derivatives
HUT41375A (en) Process for producing cristalline glutaminic acid, first of all as monosodium salt, and process for producing salts and organic concentrate produced during the process
EP0164075A3 (en) 7-oxabicycloheptane substituted thio prostaglandin analogs
HUT40083A (en) Process for producing quinolon-carboxylic acid derivatives
EP0215949A4 (en) PRODUCTION PROCESS 16-SUBSTITUTED PROSTAGLANDINE-E.
HU906329D0 (en) Process for producing pyridyl-cyclopropane-carboxylic acid derivatives
PH17551A (en) Method of producing pure monosodium glutamate
YU182185A (en) Process for producing derivatives of bromdichlorimidazole
HUT37747A (en) Process for producing sulfamoyl-guanidine derivatives
HUT37436A (en) Process for producing new cepheme-carboxylic acid derivatives
FR2562066B1 (fr) Procede de production d'isobutylene