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DK357585D0 - Fremgangsmaade til fremstilling af 2'-deoxyadenosinforbindelser - Google Patents

Fremgangsmaade til fremstilling af 2'-deoxyadenosinforbindelser

Info

Publication number
DK357585D0
DK357585D0 DK357585A DK357585A DK357585D0 DK 357585 D0 DK357585 D0 DK 357585D0 DK 357585 A DK357585 A DK 357585A DK 357585 A DK357585 A DK 357585A DK 357585 D0 DK357585 D0 DK 357585D0
Authority
DK
Denmark
Prior art keywords
deoxyadenos
preparing
compounds
procedure
deoxyadenosine
Prior art date
Application number
DK357585A
Other languages
English (en)
Other versions
DK165453C (da
DK165453B (da
DK357585A (da
Inventor
Roland Kenith Robins
Ganapathi Ramakrishna Revankar
Original Assignee
Univ Brigham Young
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Brigham Young filed Critical Univ Brigham Young
Publication of DK357585D0 publication Critical patent/DK357585D0/da
Publication of DK357585A publication Critical patent/DK357585A/da
Publication of DK165453B publication Critical patent/DK165453B/da
Application granted granted Critical
Publication of DK165453C publication Critical patent/DK165453C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK357585A 1984-08-06 1985-08-06 Fremgangsmaade til fremstilling af 2'-desoxyadenosinforbindelser DK165453C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63819284A 1984-08-06 1984-08-06
US63819284 1984-08-06

Publications (4)

Publication Number Publication Date
DK357585D0 true DK357585D0 (da) 1985-08-06
DK357585A DK357585A (da) 1986-02-07
DK165453B DK165453B (da) 1992-11-30
DK165453C DK165453C (da) 1993-04-13

Family

ID=24559020

Family Applications (1)

Application Number Title Priority Date Filing Date
DK357585A DK165453C (da) 1984-08-06 1985-08-06 Fremgangsmaade til fremstilling af 2'-desoxyadenosinforbindelser

Country Status (9)

Country Link
EP (1) EP0173059B1 (da)
JP (2) JPS61106594A (da)
AT (1) ATE48278T1 (da)
AU (1) AU572673B2 (da)
CA (1) CA1269659A (da)
DE (1) DE3574472D1 (da)
DK (1) DK165453C (da)
ES (1) ES8606383A1 (da)
ZA (1) ZA855696B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0217199A (ja) * 1988-07-05 1990-01-22 Japan Tobacco Inc ２’−デオキシ−β−アデノシンの製造方法
JPH02160799A (ja) * 1988-12-13 1990-06-20 Yuki Gosei Kogyo Co Ltd ２′−デオキシ−β−アデノシンの製造法
US5208327A (en) * 1991-12-18 1993-05-04 Ortho Pharmaceutical Corporation Intermediates useful in a synthesis of 2-chloro-2'-deoxyadenosine
EP1556400B1 (en) * 2002-09-25 2013-05-01 Brigham Young University Method for the preparation of 2-halo-2 -deoxyadenosine compounds from 2 -deoxyguanosine
SI3332789T1 (sl) 2004-12-22 2022-08-31 Merck Serono Sa, Centre Industriel Režim zdravljenja s kladaribinom za zdravljenje multiple skleroze
CA2649810A1 (en) 2006-05-24 2007-11-29 Laboratoires Serono S.A. Cladribine regimen for treating multiple sclerosis
PL1932918T3 (pl) 2006-12-15 2010-03-31 Explora Laboratories Sa Sposób otrzymywania kladrybiny
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
MX2011006890A (es) 2008-12-23 2011-07-20 Pharmasset Inc Analogos de nucleosidos.
PT2376088T (pt) 2008-12-23 2017-05-02 Gilead Pharmasset Llc Fosforamidatos de nucleósidos de 2-amino-purina 6-osubstituída
TW201031675A (en) 2008-12-23 2010-09-01 Pharmasset Inc Synthesis of purine nucleosides
US8232387B2 (en) 2009-08-18 2012-07-31 Scinopharm Taiwan, Ltd. Process for the preparation of cladribine
EP2343074A1 (en) 2009-12-23 2011-07-13 Merck Serono S.A. Use of purine analogues for treating airway diseases
WO2011113476A2 (en) 2010-03-16 2011-09-22 Cilag Ag Method for producing 2'-deoxyadenosine compounds
CL2011000716A1 (es) 2010-03-31 2012-04-20 Gilead Pharmasset Llc Formas cristalinas 1 6 de (s)-isopropil-2-(((s)-(((2r.3r.4r.5r)-5-(2,4-dioxo-3,4-dihidropirimidin-1(2h)-il)-4-fluoro-3-hidroxi-4-metil tetrahidrofuran-2-il)metoxi)(fenoxi)fosforil)amino)propanoato; composicion y combinacion farmaceutica; y su uso para tratar una infeccion por el virus de la hepatitis c.
GB201401465D0 (en) 2014-01-29 2014-03-12 Roach Arthur H Use of cladribine for treating autoimmune inflammatory disease
EP2993177A1 (en) 2014-09-05 2016-03-09 Technische Universität Berlin A chemo-enzymatic preparation method for purine nucleosides and their deaza- and aza- analogues
GB2564717A (en) 2017-07-21 2019-01-23 Chord Therapeutics S A R L Use of cladribine for treating autoimmune neuromuscular disease
MX2020005266A (es) 2017-11-24 2020-09-18 Merck Patent Gmbh Regimen de cladribina para usarse en el tratamiento de formas progresivas de esclerosis multiple.
IL301246A (en) 2020-09-10 2023-05-01 Merck Patent Gmbh Cladribine treatment regimen
GB2601786A (en) 2020-12-10 2022-06-15 Chord Therapeutics S A R L Use of cladribine for treating immune brain disease
AU2022231384A1 (en) 2021-03-03 2023-09-14 Ares Trading S.A. Improved treatment methods using dmds for the treatment of autoimmune diseases, and biomarker for predicting and/or optimising said treatment methods
DE102023123718A1 (de) 2023-09-04 2025-03-06 CHIRACON Pharma GmbH Verfahren zur Herstellung von Nukleosiden

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3225029A (en) * 1962-03-08 1965-12-21 Yamaoka Naotaka Process for the preparation of nucleosides and products obtained thereby
US3225009A (en) * 1962-05-21 1965-12-21 Scott Paper Co Ethylene dicarboxylic esters of 1,2 alkane carbonates, polymers, and copolymers thereof
DE1795357A1 (de) * 1968-09-18 1972-01-05 Schering Ag 2-Thio-pyrimidin-nucleoside
CA1264738A (en) * 1984-12-04 1990-01-23 Eli Lilly And Company Treatment of tumors in mammals

Also Published As

Publication number Publication date
JPS61106594A (ja) 1986-05-24
AU572673B2 (en) 1988-05-12
ES8606383A1 (es) 1986-04-01
CA1269659A (en) 1990-05-29
DK165453C (da) 1993-04-13
ATE48278T1 (de) 1989-12-15
JPH02359B2 (da) 1990-01-08
EP0173059A3 (en) 1987-04-29
EP0173059B1 (en) 1989-11-29
DK165453B (da) 1992-11-30
DK357585A (da) 1986-02-07
EP0173059A2 (en) 1986-03-05
ZA855696B (en) 1986-04-30
DE3574472D1 (de) 1990-01-04
ES545888A0 (es) 1986-04-01
AU4513885A (en) 1986-02-13
JPH0256497A (ja) 1990-02-26

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