ZA836680B - Naphthalenylthiazole derivatives - Google Patents
Naphthalenylthiazole derivativesInfo
- Publication number
- ZA836680B ZA836680B ZA836680A ZA836680A ZA836680B ZA 836680 B ZA836680 B ZA 836680B ZA 836680 A ZA836680 A ZA 836680A ZA 836680 A ZA836680 A ZA 836680A ZA 836680 B ZA836680 B ZA 836680B
- Authority
- ZA
- South Africa
- Prior art keywords
- sup
- derivatives
- naphthalenylthiazole
- halo
- lower alkyl
- Prior art date
Links
- CSNMPROUXVMUBU-UHFFFAOYSA-N 2-naphthalen-1-yl-1,3-thiazole Chemical class C1=CSC(C=2C3=CC=CC=C3C=CC=2)=N1 CSNMPROUXVMUBU-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- 206010012655 Diabetic complications Diseases 0.000 abstract 1
- 239000003288 aldose reductase inhibitor Substances 0.000 abstract 1
- 229940090865 aldose reductase inhibitors used in diabetes Drugs 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000004953 trihalomethyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/420,776 US4446150A (en) | 1982-09-21 | 1982-09-21 | Naphthalenylthiazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA836680B true ZA836680B (en) | 1985-04-24 |
Family
ID=23667801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA836680A ZA836680B (en) | 1982-09-21 | 1983-09-08 | Naphthalenylthiazole derivatives |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4446150A (xx) |
| EP (1) | EP0104078B1 (xx) |
| JP (1) | JPS5976075A (xx) |
| AT (1) | ATE35542T1 (xx) |
| AU (1) | AU1895383A (xx) |
| CA (1) | CA1211116A (xx) |
| DE (1) | DE3377279D1 (xx) |
| DK (1) | DK429283A (xx) |
| ES (2) | ES525726A0 (xx) |
| GR (1) | GR79051B (xx) |
| SU (1) | SU1205767A3 (xx) |
| ZA (1) | ZA836680B (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4492706A (en) * | 1983-08-01 | 1985-01-08 | American Home Products Corporation | Method of lowering lipid levels |
| CA1307537C (en) * | 1987-12-23 | 1992-09-15 | Jay E. Wrobel | N-naphthoylglycines as aldose reductase inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2474426A (en) * | 1941-12-10 | 1949-06-28 | Ilford Ltd | Cyanine dyestuffs and dyestuff intermediates |
| US2441558A (en) * | 1945-10-16 | 1948-05-18 | Eastman Kodak Co | Process for preparing nu-arylthiazolinium quaternary salts |
| US3436397A (en) * | 1966-05-23 | 1969-04-01 | American Home Prod | Dibenzocyclohepten-5-ylidene thiazolidinones |
| US3436398A (en) * | 1966-05-23 | 1969-04-01 | American Home Prod | Benzhydrylidene thiazolidinones |
| US3539585A (en) * | 1968-10-03 | 1970-11-10 | American Home Prod | 4-hydroxy-2-thiazoline-5-alkanoic acids |
| US4260609A (en) * | 1977-06-01 | 1981-04-07 | Merck & Co., Inc. | Di- and tri- substituted thiazoles |
| AU544067B2 (en) * | 1981-03-02 | 1985-05-16 | Wyeth-Ayerst Canada Inc. | Thioamides and amides. treatment of diabetes |
-
1982
- 1982-09-21 US US06/420,776 patent/US4446150A/en not_active Expired - Lifetime
-
1983
- 1983-09-08 ZA ZA836680A patent/ZA836680B/xx unknown
- 1983-09-08 AU AU18953/83A patent/AU1895383A/en not_active Abandoned
- 1983-09-12 GR GR72429A patent/GR79051B/el unknown
- 1983-09-19 ES ES525726A patent/ES525726A0/es active Granted
- 1983-09-20 AT AT83305503T patent/ATE35542T1/de not_active IP Right Cessation
- 1983-09-20 SU SU833645598A patent/SU1205767A3/ru active
- 1983-09-20 CA CA000437061A patent/CA1211116A/en not_active Expired
- 1983-09-20 DK DK429283A patent/DK429283A/da not_active Application Discontinuation
- 1983-09-20 EP EP83305503A patent/EP0104078B1/en not_active Expired
- 1983-09-20 DE DE8383305503T patent/DE3377279D1/de not_active Expired
- 1983-09-21 JP JP58176094A patent/JPS5976075A/ja active Granted
-
1985
- 1985-03-29 ES ES541712A patent/ES541712A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| SU1205767A3 (ru) | 1986-01-15 |
| ES8506662A1 (es) | 1985-08-16 |
| ATE35542T1 (de) | 1988-07-15 |
| DK429283A (da) | 1984-03-22 |
| DE3377279D1 (de) | 1988-08-11 |
| EP0104078A3 (en) | 1985-09-25 |
| EP0104078B1 (en) | 1988-07-06 |
| ES525726A0 (es) | 1985-08-16 |
| GR79051B (xx) | 1984-10-02 |
| AU1895383A (en) | 1984-03-29 |
| US4446150A (en) | 1984-05-01 |
| JPH0479344B2 (xx) | 1992-12-15 |
| ES8602711A1 (es) | 1985-12-01 |
| JPS5976075A (ja) | 1984-04-28 |
| CA1211116A (en) | 1986-09-09 |
| EP0104078A2 (en) | 1984-03-28 |
| DK429283D0 (da) | 1983-09-20 |
| ES541712A0 (es) | 1985-12-01 |
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