ZA794764B - Alpha-aryl-alpha,alpha bis((disubstituted amino)alkyl)acetamides and related compounds - Google Patents

Alpha-aryl-alpha,alpha bis((disubstituted amino)alkyl)acetamides and related compounds

Info

Publication number: ZA794764B
Authority: ZA; South Africa
Prior art keywords: alpha; acetamides; aryl; alkyl; bis
Prior art date: 1978-09-08

Application number

ZA00794764A

Other languages

English (en)

Inventor

P Yonan

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-09-08

Filing date

1979-09-07

Publication date

1981-04-29

1979-09-07 Application filed by Searle & Co filed Critical Searle & Co

1981-04-29 Publication of ZA794764B publication Critical patent/ZA794764B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA00794764A 1978-09-08 1979-09-07 Alpha-aryl-alpha,alpha bis((disubstituted amino)alkyl)acetamides and related compounds ZA794764B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/940,527 US4217306A (en)	1978-05-01	1978-09-08	α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides

Publications (1)

Publication Number	Publication Date
ZA794764B true ZA794764B (en)	1981-04-29

Family

ID=25474978

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA00794764A ZA794764B (en)	1978-09-08	1979-09-07	Alpha-aryl-alpha,alpha bis((disubstituted amino)alkyl)acetamides and related compounds

Country Status (21)

Country	Link
US (1)	US4217306A (xx)
JP (1)	JPS5592350A (xx)
AT (3)	AT364813B (xx)
AU (1)	AU5068679A (xx)
BE (1)	BE878662A (xx)
CA (1)	CA1136622A (xx)
DE (1)	DE2936287A1 (xx)
DK (1)	DK374879A (xx)
ES (1)	ES483985A1 (xx)
FI (1)	FI792780A (xx)
FR (1)	FR2435462A1 (xx)
GB (1)	GB2030984B (xx)
GR (1)	GR72494B (xx)
IL (1)	IL58200A (xx)
IT (1)	IT1120561B (xx)
NL (1)	NL7906745A (xx)
NO (1)	NO792901L (xx)
NZ (1)	NZ191505A (xx)
PT (1)	PT70151B (xx)
SE (1)	SE7907432L (xx)
ZA (1)	ZA794764B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5097035A (en) *	1984-07-09	1992-03-17	G. D. Searle & Co.	Monobasic disobutamide derivatives
US4639524A (en) *	1984-07-09	1987-01-27	G. D. Searle & Co.	Monobasic disobutamide derivatives
US4791199A (en) *	1985-09-19	1988-12-13	G. D. Searle & Co.	Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones
EP0370712A3 (en) *	1988-11-18	1991-10-02	Ajinomoto Co., Inc.	Ethylamine derivatives and hypotensives containing the same
FR2686339B1 (fr) *	1992-01-22	1994-03-11	Adir Cie	Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5432284A (en) *	1993-09-08	1995-07-11	G. D. Searle & Co.	Process for the preparation of heterocyclic alkylamide derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2884436A (en) *	1954-08-28	1959-04-28	Nl Combinatie Chem Ind	Parasympathicolytically active alpha, alpha-diphenyl-gamma-dialkylaminobutyramide compounds and manufacture thereof
US3022314A (en) *	1955-06-20	1962-02-20	Upjohn Co	Alpha-phenyl-omega-amino-alkanamides
US3022302A (en) *	1956-03-15	1962-02-20	Pharmacia Ab	Manufacture of nu, nu-disubstituted amides of aryl acetic acids
US3078275A (en) *	1956-05-28	1963-02-19	Upjohn Co	N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides
US2894955A (en) *	1956-11-19	1959-07-14	Upjohn Co	Organic compounds
US3225091A (en) *	1962-02-01	1965-12-21	Lilly Co Eli	Anticholinergic substituted butyramides
NL124729C (xx) *	1963-05-14
US4107205A (en) *	1977-03-11	1978-08-15	G. D. Searle & Co.	α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds

1978
- 1978-09-08 US US05/940,527 patent/US4217306A/en not_active Expired - Lifetime
1979
- 1979-09-07 JP JP11508979A patent/JPS5592350A/ja active Pending
- 1979-09-07 IL IL58200A patent/IL58200A/xx unknown
- 1979-09-07 CA CA000335200A patent/CA1136622A/en not_active Expired
- 1979-09-07 DE DE19792936287 patent/DE2936287A1/de not_active Withdrawn
- 1979-09-07 ZA ZA00794764A patent/ZA794764B/xx unknown
- 1979-09-07 BE BE0/197051A patent/BE878662A/fr unknown
- 1979-09-07 FR FR7922468A patent/FR2435462A1/fr active Pending
- 1979-09-07 PT PT70151A patent/PT70151B/pt unknown
- 1979-09-07 AU AU50686/79A patent/AU5068679A/en not_active Abandoned
- 1979-09-07 AT AT0592679A patent/AT364813B/de not_active IP Right Cessation
- 1979-09-07 NZ NZ191505A patent/NZ191505A/xx unknown
- 1979-09-07 GR GR59993A patent/GR72494B/el unknown
- 1979-09-07 IT IT50202/79A patent/IT1120561B/it active
- 1979-09-07 NO NO792901A patent/NO792901L/no unknown
- 1979-09-07 GB GB7931218A patent/GB2030984B/en not_active Expired
- 1979-09-07 SE SE7907432A patent/SE7907432L/xx not_active Application Discontinuation
- 1979-09-07 ES ES483985A patent/ES483985A1/es not_active Expired
- 1979-09-07 DK DK374879A patent/DK374879A/da not_active Application Discontinuation
- 1979-09-07 FI FI792780A patent/FI792780A/fi not_active Application Discontinuation
- 1979-09-10 NL NL7906745A patent/NL7906745A/nl not_active Application Discontinuation
1980
- 1980-12-10 AT AT0600280A patent/AT370088B/de not_active IP Right Cessation
- 1980-12-10 AT AT0600180A patent/AT370087B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE2936287A1 (de)	1980-03-20
DK374879A (da)	1980-03-09
ES483985A1 (es)	1980-04-16
AT370087B (de)	1983-02-25
FI792780A (fi)	1980-03-09
NO792901L (no)	1980-03-11
BE878662A (fr)	1980-03-07
CA1136622A (en)	1982-11-30
FR2435462A1 (fr)	1980-04-04
GB2030984A (en)	1980-04-16
NL7906745A (nl)	1980-03-11
ATA600180A (de)	1982-07-15
AT370088B (de)	1983-02-25
ATA592679A (de)	1981-04-15
PT70151B (pt)	1981-12-11
IT7950202A0 (it)	1979-09-07
IL58200A (en)	1982-12-31
SE7907432L (sv)	1980-03-09
GB2030984B (en)	1983-07-27
AU5068679A (en)	1980-03-27
AT364813B (de)	1981-11-25
JPS5592350A (en)	1980-07-12
IT1120561B (it)	1986-03-26
IL58200A0 (en)	1979-12-30
NZ191505A (en)	1982-03-30
ATA600280A (de)	1982-07-15
US4217306A (en)	1980-08-12
PT70151A (en)	1979-09-01
GR72494B (xx)	1983-11-15

Publication	Publication Date	Title
NZ190589A (en)	1983-04-12	N-(heterocyclicaminocarbonyl)-arylsulphonamides
GB2032015B (en)	1982-10-27	Gaskets
JPS55153779A (en)	1980-11-29	Novel amines
JPS54126175A (en)	1979-10-01	Briefcase
JPS53130617A (en)	1978-11-14	2 ajido 2 deokishigurikoshirunitoreetomataha haraidooyobisonoseizoho 2 amino mataha2 asetoamido gurikoosunoseizoho oyobigurikoshidooyobisonoseizohoho narabinigaigurikoshidoyorinarumenekikyuchakutai
GB2025974B (en)	1982-10-27	N-(diaminophosphinyl) carboxamides
CS44479A2 (en)	1985-06-13	Zpusob vyroby novych n (2 (nebo) pyrrolidinyl ( nebo py rrolidinylmethyl) benzamidu, substituovanych v poloze 2,3,4,5, 6
PH24034A (en)	1990-02-09	Novel 2-pyrrolindone compounds and processes employing same
AU523331B2 (en)	1982-07-22	Bis(polyorganosiloxanyl) amines
JPS5392769A (en)	1978-08-15	Thiazolylcinnamate nitrile process for preparing same and vermicide containing same
JPS5365890A (en)	1978-06-12	Compounds and application thereof
JPS5591875A (en)	1980-07-11	Mosfet
JPS54130540A (en)	1979-10-09	Novel nitrile compound and use for perfume drug
GB2045873B (en)	1983-01-06	Gaskets
ZA794764B (en)	1981-04-29	Alpha-aryl-alpha,alpha bis((disubstituted amino)alkyl)acetamides and related compounds
SG42983G (en)	1985-01-11	2-amino-3-benzoyl phenylacetamides and cyclic homologues
PT67765A (en)	1978-04-01	Process for preparing alpha-aril-alpha,alpha-bis-(omega-(disubstituted amino)alkyl)acetamides and related compounds
JPS54152577A (en)	1979-11-30	Clamp for bracelet
GB2040007B (en)	1983-01-26	Gaskets
CS765780A2 (en)	1985-07-16	Zpusob pripravy 1,2 bis (nikotinamido) propanu
JPS54146898A (en)	1979-11-16	Amide siloxane
ZA791752B (en)	1980-11-26	4-aza-17 beta -substituted-5 alpha -androstan-3-ones useful as 5 alpha -reductase inhibitors
ZA793937B (en)	1980-07-30	Cyclic diamides
JPS52151170A (en)	1977-12-15	Novel hydantoindiacrylate compound and curable composition containing same
GB2036199B (en)	1983-02-16	Gaskets