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ZA200807507B - Antiviral drugs for treatment of arenavirus infection - Google Patents

Antiviral drugs for treatment of arenavirus infection

Info

Publication number
ZA200807507B
ZA200807507B ZA200807507A ZA200807507A ZA200807507B ZA 200807507 B ZA200807507 B ZA 200807507B ZA 200807507 A ZA200807507 A ZA 200807507A ZA 200807507 A ZA200807507 A ZA 200807507A ZA 200807507 B ZA200807507 B ZA 200807507B
Authority
ZA
South Africa
Prior art keywords
treatment
antiviral drugs
arenavirus infection
arenavirus
infection
Prior art date
Application number
ZA200807507A
Other languages
English (en)
Inventor
Dennis E Hruby
Bolken Tove
Amberg Sean
Dai Dongcheng
Original Assignee
Siga Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siga Technologies Inc filed Critical Siga Technologies Inc
Publication of ZA200807507B publication Critical patent/ZA200807507B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200807507A 2006-03-02 2008-09-01 Antiviral drugs for treatment of arenavirus infection ZA200807507B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77810706P 2006-03-02 2006-03-02

Publications (1)

Publication Number Publication Date
ZA200807507B true ZA200807507B (en) 2009-08-26

Family

ID=38475385

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200807507A ZA200807507B (en) 2006-03-02 2008-09-01 Antiviral drugs for treatment of arenavirus infection

Country Status (8)

Country Link
US (2) US7872037B2 (ja)
EP (1) EP1988776B1 (ja)
JP (1) JP5380078B2 (ja)
AP (1) AP2267A (ja)
CA (1) CA2651943C (ja)
ES (1) ES2395101T3 (ja)
WO (1) WO2007103111A2 (ja)
ZA (1) ZA200807507B (ja)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7687641B2 (en) * 2003-06-20 2010-03-30 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US8530509B2 (en) 2003-06-20 2013-09-10 Siga Technologies, Inc. Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US8410149B2 (en) 2004-12-06 2013-04-02 Siga Technologies Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US8642596B2 (en) * 2004-12-06 2014-02-04 Siga Technologies, Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arena viruses
JP2009525338A (ja) 2006-02-01 2009-07-09 サイガ・テクノロジーズ・インコーポレーテッド 抗アレナウイルス化合物
US8791110B2 (en) 2006-02-01 2014-07-29 Siga Technologies, Inc. Anti-arenaviral compounds
US7977365B2 (en) * 2006-03-02 2011-07-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
CA2651943C (en) 2006-03-02 2015-06-30 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
US8871746B2 (en) 2006-03-02 2014-10-28 Kineta Four, LLC Antiviral drugs for treatment of arenavirus infection
WO2007100888A2 (en) 2006-03-02 2007-09-07 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
US20080033755A1 (en) * 2006-06-07 2008-02-07 Krusz John C Medical treatment modality for headache, pain, and other medical disorders
CN101034257B (zh) * 2007-04-06 2010-09-08 上海复旦天臣新技术有限公司 用于全息记录的感光薄膜及其制备方法
CA2866037C (en) * 2007-04-23 2017-05-16 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
BRPI0810928A2 (pt) 2007-05-23 2019-09-24 Siga Tech Inc "composição farmacêutica"
WO2009025743A2 (en) * 2007-08-17 2009-02-26 University Of Massachusetts Medical School Use of trail compositions as antiviral agents
CA2698075C (en) 2007-08-27 2016-04-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
US8940730B2 (en) 2007-09-18 2015-01-27 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions of treating a Flaviviridae family viral infection
US9149463B2 (en) 2007-09-18 2015-10-06 The Board Of Trustees Of The Leland Standford Junior University Methods and compositions of treating a Flaviviridae family viral infection
US9101628B2 (en) 2007-09-18 2015-08-11 The Board Of Trustees Of The Leland Stanford Junior University Methods and composition of treating a flaviviridae family viral infection
EP2203168B1 (en) * 2007-09-18 2014-07-16 Stanford University Compositions for treating a flaviviridae family viral infection
BRPI0905388A2 (pt) * 2008-01-15 2015-10-13 Siga Technologies Inc "composição farmacêutica; compostos e métodos de tratamento de infecção por arenavirus"
WO2010107739A2 (en) 2009-03-18 2010-09-23 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions of treating a flaviviridae family viral infection
WO2011062955A2 (en) * 2009-11-18 2011-05-26 University Of Massachusetts Compounds for modulating tlr2
RU2578606C2 (ru) 2010-03-23 2016-03-27 Сига Текнолоджиз, Инк Полиморфные формы соединения st-246 и способы получения
JP6200903B2 (ja) * 2012-02-17 2017-09-20 キネタ フォー エルエルシー アレナウイルス感染症の治療のための抗ウイルス薬
WO2018013430A2 (en) 2016-07-12 2018-01-18 Arisan Therapeutics Inc. Heterocyclic compounds for the treatment of arenavirus infection
CN108272838A (zh) * 2018-03-23 2018-07-13 三峡大学 小花清风藤提取物及其提取方法和应用
EP3980015A4 (en) * 2019-06-06 2024-02-21 University of Maryland, Baltimore Broad spectrum antiviral compounds targeting the ski complex

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4492708A (en) * 1982-09-27 1985-01-08 Eli Lilly And Company Antiviral benzimidazoles
DE60006541D1 (de) * 1999-06-30 2003-12-18 Merck & Co Inc Src-kinase hemmende verbindungen
AU2002337765A1 (en) * 2001-09-26 2003-04-07 Bristol-Myers Squibb Company Compounds useful for treating hepatitus c virus
ATE457025T1 (de) 2002-05-23 2010-02-15 Cytopia Res Pty Ltd Kinaseinhibitoren
US7687641B2 (en) * 2003-06-20 2010-03-30 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7737168B2 (en) 2003-06-20 2010-06-15 Siga Technologies, Inc. Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
RU2355687C2 (ru) * 2003-08-01 2009-05-20 Дженелэбс Текнолоджиз, Инк Бициклические производные имидазола в качестве средства против вирусов семейства flaviviridae
DE10348023A1 (de) 2003-10-15 2005-05-19 Imtm Gmbh Neue Alanyl-Aminopeptidasen-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen
AU2005216710A1 (en) * 2004-01-30 2005-09-09 Pfizer Inc. Therapeutic combinations
US8642596B2 (en) 2004-12-06 2014-02-04 Siga Technologies, Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arena viruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
JP2009514878A (ja) 2005-11-03 2009-04-09 レッドポイント バイオ コーポレイション ヒドラジン誘導体およびその使用
JP2009525338A (ja) * 2006-02-01 2009-07-09 サイガ・テクノロジーズ・インコーポレーテッド 抗アレナウイルス化合物
WO2007100888A2 (en) 2006-03-02 2007-09-07 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
CA2651943C (en) 2006-03-02 2015-06-30 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
US7977365B2 (en) * 2006-03-02 2011-07-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
CA2866037C (en) 2007-04-23 2017-05-16 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
BRPI0810928A2 (pt) 2007-05-23 2019-09-24 Siga Tech Inc "composição farmacêutica"
CA2698075C (en) 2007-08-27 2016-04-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
BRPI0905388A2 (pt) 2008-01-15 2015-10-13 Siga Technologies Inc "composição farmacêutica; compostos e métodos de tratamento de infecção por arenavirus"
US9029376B2 (en) 2008-06-03 2015-05-12 Siga Technologies, Inc. Small molecule inhibitors for the treatment or prevention of dengue virus infection

Also Published As

Publication number Publication date
ES2395101T3 (es) 2013-02-08
WO2007103111A8 (en) 2012-04-12
WO2007103111A3 (en) 2007-12-21
AP2267A (en) 2011-08-02
US20110172281A1 (en) 2011-07-14
EP1988776B1 (en) 2012-08-08
US7872037B2 (en) 2011-01-18
CA2651943C (en) 2015-06-30
EP1988776A2 (en) 2008-11-12
WO2007103111A2 (en) 2007-09-13
AP2008004594A0 (en) 2008-08-31
EP1988776A4 (en) 2010-09-01
JP5380078B2 (ja) 2014-01-08
US8629170B2 (en) 2014-01-14
US20070254934A1 (en) 2007-11-01
CA2651943A1 (en) 2007-09-13
JP2009528368A (ja) 2009-08-06

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