ZA200802270B - Treatment of neurodegenerative disorders - Google Patents
Treatment of neurodegenerative disordersInfo
- Publication number
- ZA200802270B ZA200802270B ZA200802270A ZA200802270A ZA200802270B ZA 200802270 B ZA200802270 B ZA 200802270B ZA 200802270 A ZA200802270 A ZA 200802270A ZA 200802270 A ZA200802270 A ZA 200802270A ZA 200802270 B ZA200802270 B ZA 200802270B
- Authority
- ZA
- South Africa
- Prior art keywords
- treatment
- neurodegenerative disorders
- neurodegenerative
- disorders
- Prior art date
Links
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05108946 | 2005-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200802270B true ZA200802270B (en) | 2009-02-25 |
Family
ID=37622051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200802270A ZA200802270B (en) | 2005-09-28 | 2008-03-10 | Treatment of neurodegenerative disorders |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20070072795A1 (xx) |
| EP (1) | EP1940447B1 (xx) |
| JP (1) | JP5096345B2 (xx) |
| KR (1) | KR20080038440A (xx) |
| CN (1) | CN101277715B (xx) |
| AR (1) | AR055654A1 (xx) |
| AU (1) | AU2006298826B2 (xx) |
| BR (1) | BRPI0616572A2 (xx) |
| CA (1) | CA2622609A1 (xx) |
| DK (1) | DK1940447T3 (xx) |
| ES (1) | ES2445035T3 (xx) |
| IL (1) | IL189853A (xx) |
| PL (1) | PL1940447T3 (xx) |
| RU (1) | RU2467761C2 (xx) |
| SI (1) | SI1940447T1 (xx) |
| TW (1) | TWI380824B (xx) |
| WO (1) | WO2007039436A1 (xx) |
| ZA (1) | ZA200802270B (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2008002053A1 (es) | 2007-07-17 | 2009-05-22 | Hoffmann La Roche | Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion. |
| AR067536A1 (es) | 2007-07-17 | 2009-10-14 | Hoffmann La Roche | Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea |
| RU2515914C1 (ru) * | 2013-02-12 | 2014-05-20 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика" | Гибридный белок на основе рекомбинантного эритропоэтина человека, обладающий пролонгированным действием (варианты), и способ его получения |
| RU2561050C2 (ru) | 2013-08-28 | 2015-08-20 | Федеральное государственное бюджетное учреждение науки Институт биофизики клетки Российской академии наук (ИБК РАН) | Применение белка yb-1 и его фрагментов для изготовления лекарственных средств при лечении болезни альцгеймера |
| AR113091A1 (es) * | 2018-09-27 | 2020-01-22 | Univ Nacional Del Litoral | Eritropoyetina humana modificada |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US644077A (en) * | 1898-08-01 | 1900-02-27 | Farbenfabriken Of Elberfeld Company | Acetyl salicylic acid. |
| FR2646438B1 (fr) * | 1989-03-20 | 2007-11-02 | Pasteur Institut | Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration |
| US5641670A (en) * | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
| US5968502A (en) * | 1991-11-05 | 1999-10-19 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
| US5672662A (en) * | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| US6703381B1 (en) * | 1998-08-14 | 2004-03-09 | Nobex Corporation | Methods for delivery therapeutic compounds across the blood-brain barrier |
| JP2003520194A (ja) * | 1999-04-13 | 2003-07-02 | ザ ケネス エス．ウォーレン インスティテュート，インコーポレーテッド | 末梢投与したエリスロポエチンによる興奮組織機能のモジュレート |
| US6225895B1 (en) * | 1999-05-26 | 2001-05-01 | Floyd E. Bigelow, Jr. | Towed vehicle monitor system |
| CZ299516B6 (cs) * | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem |
| DE60109625T3 (de) * | 2000-05-15 | 2017-08-03 | F. Hoffmann-La Roche Ag | Flüssige arzneizubereitung enthaltend ein erythropoietin derivat |
| WO2002003848A2 (en) * | 2000-07-10 | 2002-01-17 | Naito Albert T | Method for opening the blood-brain barrier |
| DE10043457A1 (de) * | 2000-09-04 | 2002-03-28 | Hannelore Ehrenreich | Verfahren zur Behandlung von Schizophrenie und verwandten Psychosen sowie Verwendung von Erythropoietin oder Erythropoietinderivaten zur Behandlung von Schizophrenien und verwandten Psychosen |
| DE60144439D1 (de) * | 2000-12-20 | 2011-05-26 | Hoffmann La Roche | Konjugate von erythropoietin (epo) mit polyethylenglykol (peg) |
| US6531121B2 (en) * | 2000-12-29 | 2003-03-11 | The Kenneth S. Warren Institute, Inc. | Protection and enhancement of erythropoietin-responsive cells, tissues and organs |
| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| US7767643B2 (en) * | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| EP1535065A4 (en) * | 2002-06-11 | 2007-07-11 | Burnham Inst | NEUROPROTECTOR SYNERGY OF ERYTHROPOIETIN AND INSULIN-LIKE GROWTH FACTOR |
| KR20060019501A (ko) * | 2002-07-01 | 2006-03-03 | 더 케네쓰 에스. 워렌 인스티튜트 인코포레이티드 | 응답 세포, 조직 및 기관을 보호, 회복 및 향상시키기위한 재조합 조직 보호 사이토카인 및 이를 코딩하는 핵산 |
| US7459436B2 (en) * | 2002-11-22 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| US7718363B2 (en) * | 2003-04-25 | 2010-05-18 | The Kenneth S. Warren Institute, Inc. | Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds |
| EA200501828A1 (ru) * | 2003-05-19 | 2006-08-25 | Дзе Кеннет С. Уоррен Инститьют, Инк. | Тканепротекторные цитокины с увеличенным терапевтическим окном для защиты, восстановления и стимулирования реагирующих клеток, тканей и органов |
| WO2005058347A1 (en) * | 2003-12-19 | 2005-06-30 | F. Hoffmann-La Roche Ag | Use of erythropoietin in the treatment of disturbances of iron distribution in chronic inflammatory intestinal diseases |
| ES2354909T3 (es) * | 2005-09-28 | 2011-03-21 | F. Hoffmann-La Roche Ag | Derivados de indol-3-il-carbonil-azaespiro como antagonistas receptores de la vasopresina. |
-
2005
- 2005-09-28 US US11/237,505 patent/US20070072795A1/en not_active Abandoned
-
2006
- 2006-09-18 AU AU2006298826A patent/AU2006298826B2/en not_active Ceased
- 2006-09-18 CN CN2006800360941A patent/CN101277715B/zh not_active Expired - Fee Related
- 2006-09-18 RU RU2008116309/15A patent/RU2467761C2/ru not_active IP Right Cessation
- 2006-09-18 PL PL06793581T patent/PL1940447T3/pl unknown
- 2006-09-18 JP JP2008532719A patent/JP5096345B2/ja not_active Expired - Fee Related
- 2006-09-18 CA CA002622609A patent/CA2622609A1/en not_active Abandoned
- 2006-09-18 EP EP06793581.7A patent/EP1940447B1/en not_active Not-in-force
- 2006-09-18 KR KR1020087007412A patent/KR20080038440A/ko not_active Ceased
- 2006-09-18 WO PCT/EP2006/066438 patent/WO2007039436A1/en active Application Filing
- 2006-09-18 SI SI200631739T patent/SI1940447T1/sl unknown
- 2006-09-18 ES ES06793581.7T patent/ES2445035T3/es active Active
- 2006-09-18 BR BRPI0616572-9A patent/BRPI0616572A2/pt not_active Application Discontinuation
- 2006-09-18 DK DK06793581.7T patent/DK1940447T3/da active
- 2006-09-25 TW TW095135363A patent/TWI380824B/zh not_active IP Right Cessation
- 2006-09-26 AR ARP060104198A patent/AR055654A1/es not_active Application Discontinuation
-
2008
- 2008-02-28 IL IL189853A patent/IL189853A/en not_active IP Right Cessation
- 2008-03-10 ZA ZA200802270A patent/ZA200802270B/xx unknown
- 2008-09-19 US US12/284,277 patent/US20100267632A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20080038440A (ko) | 2008-05-06 |
| CN101277715A (zh) | 2008-10-01 |
| TW200727911A (en) | 2007-08-01 |
| WO2007039436A1 (en) | 2007-04-12 |
| CN101277715B (zh) | 2013-03-27 |
| US20070072795A1 (en) | 2007-03-29 |
| JP5096345B2 (ja) | 2012-12-12 |
| ES2445035T3 (es) | 2014-02-27 |
| JP2009510008A (ja) | 2009-03-12 |
| RU2467761C2 (ru) | 2012-11-27 |
| DK1940447T3 (da) | 2014-01-20 |
| IL189853A0 (en) | 2008-11-03 |
| CA2622609A1 (en) | 2007-04-12 |
| AU2006298826A1 (en) | 2007-04-12 |
| SI1940447T1 (sl) | 2014-03-31 |
| BRPI0616572A2 (pt) | 2009-11-24 |
| RU2008116309A (ru) | 2009-11-10 |
| TWI380824B (zh) | 2013-01-01 |
| US20100267632A1 (en) | 2010-10-21 |
| IL189853A (en) | 2012-06-28 |
| EP1940447A1 (en) | 2008-07-09 |
| EP1940447B1 (en) | 2013-11-27 |
| PL1940447T3 (pl) | 2014-04-30 |
| AU2006298826B2 (en) | 2010-04-01 |
| AR055654A1 (es) | 2007-08-29 |
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