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ZA200607648B - Kinase inhibitors - Google Patents

Kinase inhibitors

Info

Publication number
ZA200607648B
ZA200607648B ZA200607648A ZA200607648A ZA200607648B ZA 200607648 B ZA200607648 B ZA 200607648B ZA 200607648 A ZA200607648 A ZA 200607648A ZA 200607648 A ZA200607648 A ZA 200607648A ZA 200607648 B ZA200607648 B ZA 200607648B
Authority
ZA
South Africa
Prior art keywords
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
ZA200607648A
Other languages
English (en)
Inventor
Rosanne Bonjouklian
Chuan Shih
Prado Miriam Filadelfa Del
Pramila Kotiyan
Sheila Pleite Selgas
Chafiq Hamdouchi Hamdouchi
Dios Alfonso De
Aguado Carlos Jaramillo
Mary Margaret Mader
Concepcion Sanchez-Martinez
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34837430&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200607648(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA200607648B publication Critical patent/ZA200607648B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200607648A 2004-01-30 2006-09-12 Kinase inhibitors ZA200607648B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54083004P 2004-01-30 2004-01-30

Publications (1)

Publication Number Publication Date
ZA200607648B true ZA200607648B (en) 2008-06-25

Family

ID=34837430

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200607648A ZA200607648B (en) 2004-01-30 2006-09-12 Kinase inhibitors

Country Status (25)

Country Link
US (2) US7582652B2 (uk)
EP (1) EP1713805B1 (uk)
CN (1) CN100516064C (uk)
AR (1) AR047466A1 (uk)
AT (1) ATE433449T1 (uk)
AU (1) AU2005210459B2 (uk)
CA (1) CA2559128C (uk)
CY (1) CY1109234T1 (uk)
DE (1) DE602005014848D1 (uk)
DK (1) DK1713805T3 (uk)
DO (1) DOP2005000010A (uk)
ES (1) ES2326819T3 (uk)
IL (1) IL178103A (uk)
MY (1) MY143516A (uk)
NZ (1) NZ549780A (uk)
PE (1) PE20050689A1 (uk)
PL (1) PL1713805T3 (uk)
PT (1) PT1713805E (uk)
RU (1) RU2348635C2 (uk)
SI (1) SI1713805T1 (uk)
SV (1) SV2006002001A (uk)
TW (1) TWI332003B (uk)
UA (1) UA85505C2 (uk)
WO (1) WO2005075478A1 (uk)
ZA (1) ZA200607648B (uk)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI332003B (en) * 2004-01-30 2010-10-21 Lilly Co Eli Kinase inhibitors
US7776869B2 (en) * 2004-10-18 2010-08-17 Amgen Inc. Heteroaryl-substituted alkyne compounds and method of use
EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
AU2011254242B2 (en) * 2010-05-17 2015-10-29 Incozen Therapeutics Pvt. Ltd. Novel 3,5-disubstitued-3H-imidazo[4,5-b]pyridine and 3,5- disubstitued -3H-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of protein kinases
AR083868A1 (es) 2010-12-03 2013-03-27 Lilly Co Eli Compuestos de oxazol[5,4-b]piridin-5-ilo
CA2850559C (en) 2011-11-11 2016-11-29 Eli Lilly And Company Combination therapy for ovarian cancer
JP2015533859A (ja) * 2012-07-23 2015-11-26 アクロン大学 有機修飾モンモリロナイトを含有するポリイソブチレン系ポリウレタン
TWI731317B (zh) 2013-12-10 2021-06-21 美商健臻公司 原肌球蛋白相關之激酶（ｔｒｋ）抑制劑
MY195799A (en) 2014-12-18 2023-02-21 Genzyme Corp Pharmaceutical Formulations of Tropomyosin-Related Kinase (TRK) Inhibitors
MA41179A (fr) 2014-12-19 2017-10-24 Cancer Research Tech Ltd Composés inhibiteurs de parg
SG11201705821XA (en) * 2015-03-02 2017-08-30 Rigel Pharmaceuticals Inc TGF-ß INHIBITORS
MX2020003961A (es) 2017-10-05 2020-09-22 Fulcrum Therapeutics Inc Uso de inhibidores de p38 para reducir la expresion de dux4.
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
US10899869B2 (en) 2019-01-24 2021-01-26 The University Of Akron Glycerol containing polyurethanes and polyurethane nanocomposites
TW202112368A (zh) 2019-06-13 2021-04-01 荷蘭商法西歐知識產權股份有限公司 用於治療有關dux4表現之疾病的抑制劑組合
AU2023239344A1 (en) 2022-03-23 2024-10-10 Ideaya Biosciences, Inc. Piperazine substituted indazole compounds as inhibitors of parg

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9300141A (es) 1992-01-13 1994-07-29 Smithkline Beecham Corp Compuestos de imidazol novedosos, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen.
DE19503806A1 (de) * 1994-02-11 1995-08-17 Bernhardt Apparatebau Gmbh Co Vorrichtung zum Aufblasen eines Behälters oder eines Schwimmkörpers, insbesondere einer Schwimmweste
US6426360B1 (en) 1994-07-28 2002-07-30 G D Searle & Co. 4,5-substituted imidazolyl compounds for the treatment of inflammation
US5620999A (en) 1994-07-28 1997-04-15 Weier; Richard M. Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
US5717100A (en) 1995-10-06 1998-02-10 Merck & Co., Inc. Substituted imidazoles having anti-cancer and cytokine inhibitory activity
EP0956018A4 (en) 1996-08-21 2000-01-12 Smithkline Beecham Corp IMIDAZOLE COMPOUNDS, COMPOSITIONS CONTAINING THEM AND THEIR USE
US6087496A (en) 1998-05-22 2000-07-11 G. D. Searle & Co. Substituted pyrazoles suitable as p38 kinase inhibitors
US6180632B1 (en) 1997-05-28 2001-01-30 Aventis Pharmaceuticals Products Inc. Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
AU8167398A (en) 1997-06-30 1999-01-19 Temple University - Of The Commonwealth System Of Higher Education Method for treating vulvar vestibulitis
AR016294A1 (es) * 1997-07-02 2001-07-04 Smithkline Beecham Corp Compuesto de imidazol sustituido, composicion farmaceutica que la contiene, su uso en la fabricacion de un medicamento y procedimiento para supreparacion
UA62972C2 (en) * 1997-07-03 2004-01-15 Application of imidazopyrimidins and imidazopyridins for the treatment of neural disorders
WO1999032121A1 (en) 1997-12-19 1999-07-01 Smithkline Beecham Corporation Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses
US6207687B1 (en) 1998-07-31 2001-03-27 Merck & Co., Inc. Substituted imidazoles having cytokine inhibitory activity
US6291457B1 (en) 1999-07-01 2001-09-18 Merck & Co., Inc. Compounds having cytokine inhibitory activity
US6608072B1 (en) * 1999-10-27 2003-08-19 Novartis Ag Thiazole compounds and their pharmaceutical use
GB0007405D0 (en) 2000-03-27 2000-05-17 Smithkline Beecham Corp Compounds
MXPA03008144A (es) 2001-03-09 2003-12-12 Pfizer Prod Inc Nuevos compuestos antiinflamatorios de triazolopiridinas.
HUP0303829A3 (en) 2001-04-16 2006-02-28 Tanabe Seiyaku Co Large conductance calcium-acitvated k channel opener compounds, use thereof and pharmaceutical compositions containing them
WO2003062215A1 (en) 2002-01-25 2003-07-31 Kylix Pharmaceuticals B.V. 4(hetero-) aryl substituted (thia-/oxa-/pyra) zoles for inhibition of tie-2
EP1537112B1 (en) 2002-08-06 2006-04-19 Astrazeneca AB Condensed pyridines and pyrimidines with tie2 (tek) activity
TWI332003B (en) * 2004-01-30 2010-10-21 Lilly Co Eli Kinase inhibitors

Also Published As

Publication number Publication date
WO2005075478A1 (en) 2005-08-18
TW200526660A (en) 2005-08-16
RU2348635C2 (ru) 2009-03-10
RU2006138606A (ru) 2008-05-10
SI1713805T1 (sl) 2009-10-31
CY1109234T1 (el) 2014-07-02
AU2005210459B2 (en) 2010-10-21
ES2326819T3 (es) 2009-10-20
PE20050689A1 (es) 2005-09-27
AR047466A1 (es) 2006-01-18
PL1713805T3 (pl) 2009-10-30
DE602005014848D1 (de) 2009-07-23
ATE433449T1 (de) 2009-06-15
HK1100141A1 (en) 2007-09-07
EP1713805B1 (en) 2009-06-10
CA2559128C (en) 2013-04-16
US20090036445A1 (en) 2009-02-05
MY143516A (en) 2011-05-31
IL178103A (en) 2011-04-28
NZ549780A (en) 2010-01-29
US20090318443A1 (en) 2009-12-24
EP1713805A1 (en) 2006-10-25
TWI332003B (en) 2010-10-21
PT1713805E (pt) 2009-08-20
CN100516064C (zh) 2009-07-22
CN1938302A (zh) 2007-03-28
DOP2005000010A (es) 2005-11-15
CA2559128A1 (en) 2005-08-18
SV2006002001A (es) 2006-02-15
DK1713805T3 (da) 2009-08-17
AU2005210459A1 (en) 2005-08-18
US7582652B2 (en) 2009-09-01
UA85505C2 (en) 2009-01-26

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