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DOP2005000010A - Inhibidores de quinasa - Google Patents

Inhibidores de quinasa

Info

Publication number
DOP2005000010A
DOP2005000010A DO2005000010A DO2005000010A DOP2005000010A DO P2005000010 A DOP2005000010 A DO P2005000010A DO 2005000010 A DO2005000010 A DO 2005000010A DO 2005000010 A DO2005000010 A DO 2005000010A DO P2005000010 A DOP2005000010 A DO P2005000010A
Authority
DO
Dominican Republic
Prior art keywords
inhibitors
quinase
quinase inhibitors
formula
present
Prior art date
Application number
DO2005000010A
Other languages
English (en)
Inventor
Rosanne Bonjouklian
Chafiq Hamdouchi Hamdouchi
Chuan Shih
Dios Alfonso De
Prado Miriam Filadelfa Del
Carlos Jaramillo Aguado
Pramila Kotiyan
Mary Margaret Mader
Selgas Sheila Pleite
Martinez Concepcion Sanchez
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34837430&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2005000010(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DOP2005000010A publication Critical patent/DOP2005000010A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona inhibidores de quinasa de fórmula I:
DO2005000010A 2004-01-30 2005-01-27 Inhibidores de quinasa DOP2005000010A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54083004P 2004-01-30 2004-01-30

Publications (1)

Publication Number Publication Date
DOP2005000010A true DOP2005000010A (es) 2005-11-15

Family

ID=34837430

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2005000010A DOP2005000010A (es) 2004-01-30 2005-01-27 Inhibidores de quinasa

Country Status (25)

Country Link
US (2) US7582652B2 (es)
EP (1) EP1713805B1 (es)
CN (1) CN100516064C (es)
AR (1) AR047466A1 (es)
AT (1) ATE433449T1 (es)
AU (1) AU2005210459B2 (es)
CA (1) CA2559128C (es)
CY (1) CY1109234T1 (es)
DE (1) DE602005014848D1 (es)
DK (1) DK1713805T3 (es)
DO (1) DOP2005000010A (es)
ES (1) ES2326819T3 (es)
IL (1) IL178103A (es)
MY (1) MY143516A (es)
NZ (1) NZ549780A (es)
PE (1) PE20050689A1 (es)
PL (1) PL1713805T3 (es)
PT (1) PT1713805E (es)
RU (1) RU2348635C2 (es)
SI (1) SI1713805T1 (es)
SV (1) SV2006002001A (es)
TW (1) TWI332003B (es)
UA (1) UA85505C2 (es)
WO (1) WO2005075478A1 (es)
ZA (1) ZA200607648B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI332003B (en) * 2004-01-30 2010-10-21 Lilly Co Eli Kinase inhibitors
US7776869B2 (en) * 2004-10-18 2010-08-17 Amgen Inc. Heteroaryl-substituted alkyne compounds and method of use
EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
EA025281B9 (ru) * 2010-05-17 2017-08-31 Инкозен Терапьютикс Пвт. Лтд. СОЕДИНЕНИЯ 3,5-ДИЗАМЕЩЕННОГО-3H-ИМИДАЗО[4,5-b]ПИРИДИНА И 3,5-ДИЗАМЕЩЕННОГО-3H-[1,2,3]ТРИАЗОЛО[4,5-b]ПИРИДИНА КАК МОДУЛЯТОРЫ ПРОТЕИНКИНАЗ
TWI410425B (zh) * 2010-12-03 2013-10-01 Lilly Co Eli 唑并［５，４－ｂ］吡啶－５－基化合物
EA026297B1 (ru) * 2011-11-11 2017-03-31 Эли Лилли Энд Компани Комбинированная терапия рака яичников
EP2875071A4 (en) * 2012-07-23 2015-12-23 Univ Akron POLYURETHANE ON POLYISOBUTYLENE BASE WITH ORGANICALLY MODIFIED MONTMORILLONITE
US9067914B1 (en) 2013-12-10 2015-06-30 Genzyme Corporation Tropomyosin-related kinase (TRK) inhibitors
CN110950862B (zh) 2014-12-18 2024-01-05 建新公司 原肌球蛋白相关激酶(trk)抑制剂的药物制剂
MA41179A (fr) 2014-12-19 2017-10-24 Cancer Research Tech Ltd Composés inhibiteurs de parg
ES2789331T3 (es) 2015-03-02 2020-10-26 Rigel Pharmaceuticals Inc Inhibidores de TGF-beta
JP7012152B2 (ja) 2017-10-05 2022-02-10 フルクラム セラピューティクス，インコーポレイテッド Ｆｓｈｄの治療のためにｄｕｘ４および下流遺伝子発現を低減するｐ３８キナーゼ阻害剤
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
US10899869B2 (en) 2019-01-24 2021-01-26 The University Of Akron Glycerol containing polyurethanes and polyurethane nanocomposites
TW202112368A (zh) 2019-06-13 2021-04-01 荷蘭商法西歐知識產權股份有限公司 用於治療有關dux4表現之疾病的抑制劑組合
CR20240391A (es) 2022-03-23 2024-11-05 Ideaya Biosciences Inc Compuestos de indazol sustituidos con piperazina como inhibidores de parg

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9300141A (es) 1992-01-13 1994-07-29 Smithkline Beecham Corp Compuestos de imidazol novedosos, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen.
DE19503806A1 (de) * 1994-02-11 1995-08-17 Bernhardt Apparatebau Gmbh Co Vorrichtung zum Aufblasen eines Behälters oder eines Schwimmkörpers, insbesondere einer Schwimmweste
US5620999A (en) 1994-07-28 1997-04-15 Weier; Richard M. Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
US6426360B1 (en) 1994-07-28 2002-07-30 G D Searle & Co. 4,5-substituted imidazolyl compounds for the treatment of inflammation
US5717100A (en) 1995-10-06 1998-02-10 Merck & Co., Inc. Substituted imidazoles having anti-cancer and cytokine inhibitory activity
WO1998007425A1 (en) 1996-08-21 1998-02-26 Smithkline Beecham Corporation Imidazole compounds, compositions and use
US6087496A (en) 1998-05-22 2000-07-11 G. D. Searle & Co. Substituted pyrazoles suitable as p38 kinase inhibitors
US6180632B1 (en) 1997-05-28 2001-01-30 Aventis Pharmaceuticals Products Inc. Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
WO1999000130A1 (en) 1997-06-30 1999-01-07 Temple University - Of The Commonwealth System Of Higher Education Method for treating vulvar vestibulitis
AR016294A1 (es) * 1997-07-02 2001-07-04 Smithkline Beecham Corp Compuesto de imidazol sustituido, composicion farmaceutica que la contiene, su uso en la fabricacion de un medicamento y procedimiento para supreparacion
UA62972C2 (en) * 1997-07-03 2004-01-15 Application of imidazopyrimidins and imidazopyridins for the treatment of neural disorders
EP1037639A4 (en) 1997-12-19 2002-04-17 Smithkline Beecham Corp HETEROARYL-SUBSTITUTED IMIDAZOLE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS AND USES
US6207687B1 (en) 1998-07-31 2001-03-27 Merck & Co., Inc. Substituted imidazoles having cytokine inhibitory activity
US6291457B1 (en) 1999-07-01 2001-09-18 Merck & Co., Inc. Compounds having cytokine inhibitory activity
AU7922900A (en) * 1999-10-27 2001-05-08 Novartis Ag Thiazole and imidazo (4,5-b) pyridine compounds and their pharmaceutical use
GB0007405D0 (en) * 2000-03-27 2000-05-17 Smithkline Beecham Corp Compounds
HRP20030719A2 (en) 2001-03-09 2005-04-30 Pfizer Products Inc. Triazolopyridines as anri-inflammatory agents
IL158168A0 (en) 2001-04-16 2004-03-28 Tanabe Seiyaku Co 5-membered, nitrogen-containing heterocyclic compounds and pharmaceutical compositions containing the same
EP1467981A1 (en) 2002-01-25 2004-10-20 Kylix Pharmaceuticals B.V. 4(hetero-) aryl substituted (thia-/oxa-/pyra) zoles for inhibition of tie-2
KR20050067383A (ko) 2002-08-06 2005-07-01 아스트라제네카 아베 Ｔｉｅ2(ｔｅｋ) 활성을 갖는 축합 피리딘 및 피리미딘
TWI332003B (en) * 2004-01-30 2010-10-21 Lilly Co Eli Kinase inhibitors

Also Published As

Publication number Publication date
DK1713805T3 (da) 2009-08-17
CN100516064C (zh) 2009-07-22
AU2005210459A1 (en) 2005-08-18
WO2005075478A1 (en) 2005-08-18
AR047466A1 (es) 2006-01-18
ATE433449T1 (de) 2009-06-15
ZA200607648B (en) 2008-06-25
RU2348635C2 (ru) 2009-03-10
RU2006138606A (ru) 2008-05-10
PE20050689A1 (es) 2005-09-27
US7582652B2 (en) 2009-09-01
SV2006002001A (es) 2006-02-15
SI1713805T1 (sl) 2009-10-31
UA85505C2 (en) 2009-01-26
TW200526660A (en) 2005-08-16
CA2559128A1 (en) 2005-08-18
US20090036445A1 (en) 2009-02-05
IL178103A (en) 2011-04-28
US20090318443A1 (en) 2009-12-24
HK1100141A1 (en) 2007-09-07
PT1713805E (pt) 2009-08-20
MY143516A (en) 2011-05-31
NZ549780A (en) 2010-01-29
PL1713805T3 (pl) 2009-10-30
CY1109234T1 (el) 2014-07-02
EP1713805B1 (en) 2009-06-10
AU2005210459B2 (en) 2010-10-21
CN1938302A (zh) 2007-03-28
ES2326819T3 (es) 2009-10-20
TWI332003B (en) 2010-10-21
EP1713805A1 (en) 2006-10-25
CA2559128C (en) 2013-04-16
DE602005014848D1 (de) 2009-07-23

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