ZA200400313B - Use of BIBN4096 in combination with other antimigraine drugs for the treatment of migraine. - Google Patents

Use of BIBN4096 in combination with other antimigraine drugs for the treatment of migraine.

Info

Publication number: ZA200400313B
Authority: ZA; South Africa
Prior art keywords: bibn4096; migraine; treatment; combination; antimigraine drugs
Prior art date: 2001-08-17

Application number

ZA200400313A

Other languages

English (en)

Inventor

Henri Doods

Klaus Rudolf

Wolfgang Eberlein

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-17

Filing date

2004-01-15

Publication date

2004-11-01

2004-01-15 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2004-11-01 Publication of ZA200400313B publication Critical patent/ZA200400313B/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Obesity (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Nutrition Science (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

ZA200400313A 2001-08-17 2004-01-15 Use of BIBN4096 in combination with other antimigraine drugs for the treatment of migraine. ZA200400313B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10139410A DE10139410A1 (de)	2001-08-17	2001-08-17	Verwendung von BIBN4096 in Kombination mit anderen Arzneistoffen gegen Migräne für die Behandlung von Migräne

Publications (1)

Publication Number	Publication Date
ZA200400313B true ZA200400313B (en)	2004-11-01

Family

ID=7695082

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200400313A ZA200400313B (en)	2001-08-17	2004-01-15	Use of BIBN4096 in combination with other antimigraine drugs for the treatment of migraine.

Country Status (22)

Country	Link
EP (1)	EP1420790B1 (ja)
JP (1)	JP2005503382A (ja)
KR (1)	KR20040027892A (ja)
CN (1)	CN1543347A (ja)
AR (1)	AR036265A1 (ja)
AT (1)	ATE304854T1 (ja)
BR (1)	BR0211970A (ja)
CA (1)	CA2454083A1 (ja)
CO (1)	CO5560577A2 (ja)
DE (2)	DE10139410A1 (ja)
EA (1)	EA200400253A1 (ja)
EC (1)	ECSP044979A (ja)
ES (1)	ES2250733T3 (ja)
HR (1)	HRP20040150A2 (ja)
HU (1)	HUP0401484A3 (ja)
IL (1)	IL159879A0 (ja)
MX (1)	MXPA04001364A (ja)
NO (1)	NO20041024D0 (ja)
PL (1)	PL365482A1 (ja)
UY (1)	UY27416A1 (ja)
WO (1)	WO2003015787A1 (ja)
ZA (1)	ZA200400313B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8465468B1 (en)	2000-06-29	2013-06-18	Becton, Dickinson And Company	Intradermal delivery of substances
DE10207026A1 (de) *	2002-02-20	2003-08-28	Boehringer Ingelheim Kg	Pulverinhalativum, enthaltend den CGRP-Antagonisten BIBN4096 und Verfahren zu dessen Herstellung
EP1374870A1 (en) *	2002-06-24	2004-01-02	Rita Dobmeyer	Medication for the treatment or prevention of migraine
DE10314617A1 (de) *	2003-04-01	2004-10-14	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung des Hydrochlorids der Wirkstoffbase 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl)-1-piperidinyl]-carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazin in Kombination mit Sumatriptan zur Behandlung von Migräne
DE10338399A1 (de) *	2003-08-18	2005-03-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Mikropartikel, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-Iysyl]-4-(4-pyridinyl)-piperazin, Verfahren zu deren Herstellung sowie deren Verwendung als Inhalaltionspulver
DE10338407A1 (de) *	2003-08-18	2005-03-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Inhalationspulver enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazin
DE10338402A1 (de) *	2003-08-18	2005-03-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Sprühgetrocknetes, amorphes BIBN 4096, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum
DE10338403A1 (de) *	2003-08-18	2005-03-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pulverformulierung, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl]-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyrindinyl)-piperazin, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum
US20050065094A1 (en)	2003-09-05	2005-03-24	Boehringer Ingelheim International Gmbh	Use of telmisartan for the prevention and treatment of vascular headache
JP2007533685A (ja) *	2004-04-20	2007-11-22	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	偏頭痛を治療するためのセロトニン再吸収阻害剤と組合わせたｃｇｒｐアンタゴニストの使用
EP1744784A2 (en) *	2004-05-11	2007-01-24	Becton, Dickinson and Company	Formulations of anti-pain agents and methods of using the same
DE102004063753A1 (de) *	2004-12-29	2006-07-13	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung ausgewählter CGRP-Antagonisten in Kombination mit anderen Arzneistoffen gegen Migräne für die Behandlung von Migräne
CN102526031A (zh) *	2010-12-27	2012-07-04	湖南九典制药有限公司	一种鼻腔内使用的舒马普坦药物组合物及其制备方法
CN103385876B (zh) *	2012-05-08	2016-01-13	四川滇虹医药开发有限公司	一种夫罗曲坦的药物组合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EA004037B1 (ru) *	1996-09-10	2003-12-25	Др. Карл Томэ ГмбХ	Модифицированные аминокислоты и лекарственное средство на их основе
DE19937304C2 (de) *	1999-08-10	2003-08-21	Boehringer Ingelheim Pharma	Verwendung von CGRP-Antagonisten zur Bekämpfung menopausaler Hitzewallungen

2001
- 2001-08-17 DE DE10139410A patent/DE10139410A1/de not_active Withdrawn
2002
- 2002-08-10 ES ES02794772T patent/ES2250733T3/es not_active Expired - Lifetime
- 2002-08-10 HU HU0401484A patent/HUP0401484A3/hu unknown
- 2002-08-10 WO PCT/EP2002/008993 patent/WO2003015787A1/en active IP Right Grant
- 2002-08-10 DE DE60206289T patent/DE60206289T2/de not_active Expired - Fee Related
- 2002-08-10 JP JP2003520746A patent/JP2005503382A/ja active Pending
- 2002-08-10 PL PL02365482A patent/PL365482A1/xx not_active Application Discontinuation
- 2002-08-10 MX MXPA04001364A patent/MXPA04001364A/es unknown
- 2002-08-10 EA EA200400253A patent/EA200400253A1/ru unknown
- 2002-08-10 CN CNA028161327A patent/CN1543347A/zh active Pending
- 2002-08-10 KR KR10-2004-7002356A patent/KR20040027892A/ko not_active Application Discontinuation
- 2002-08-10 AT AT02794772T patent/ATE304854T1/de not_active IP Right Cessation
- 2002-08-10 BR BR0211970-6A patent/BR0211970A/pt active Pending
- 2002-08-10 IL IL15987902A patent/IL159879A0/xx unknown
- 2002-08-10 CA CA002454083A patent/CA2454083A1/en not_active Abandoned
- 2002-08-10 EP EP02794772A patent/EP1420790B1/en not_active Expired - Lifetime
- 2002-08-14 UY UY27416A patent/UY27416A1/es not_active Application Discontinuation
- 2002-08-16 AR ARP020103101A patent/AR036265A1/es not_active Suspension/Interruption
2004
- 2004-01-15 ZA ZA200400313A patent/ZA200400313B/xx unknown
- 2004-02-12 CO CO04012009A patent/CO5560577A2/es not_active Application Discontinuation
- 2004-02-16 NO NO20041024A patent/NO20041024D0/no not_active Application Discontinuation
- 2004-02-16 HR HR20040150A patent/HRP20040150A2/hr not_active Application Discontinuation
- 2004-02-16 EC EC2004004979A patent/ECSP044979A/es unknown

Also Published As

Publication number	Publication date
BR0211970A (pt)	2004-09-21
HRP20040150A2 (en)	2004-06-30
HUP0401484A2 (hu)	2004-12-28
DE60206289D1 (de)	2006-02-02
UY27416A1 (es)	2003-03-31
CO5560577A2 (es)	2005-09-30
AR036265A1 (es)	2004-08-25
MXPA04001364A (es)	2004-05-27
EP1420790A1 (en)	2004-05-26
IL159879A0 (en)	2004-06-20
PL365482A1 (en)	2005-01-10
ECSP044979A (es)	2004-04-28
ES2250733T3 (es)	2006-04-16
WO2003015787A1 (en)	2003-02-27
HUP0401484A3 (en)	2007-03-28
EA200400253A1 (ru)	2004-08-26
DE10139410A1 (de)	2003-02-27
ATE304854T1 (de)	2005-10-15
CA2454083A1 (en)	2003-02-27
CN1543347A (zh)	2004-11-03
DE60206289T2 (de)	2006-06-08
JP2005503382A (ja)	2005-02-03
KR20040027892A (ko)	2004-04-01
NO20041024D0 (no)	2004-02-16
EP1420790B1 (en)	2005-09-21

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