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ZA200307507B - Phenyl heterocyclyl ether derivatives as serotonin re-uptake inhibitors. - Google Patents

Phenyl heterocyclyl ether derivatives as serotonin re-uptake inhibitors. Download PDF

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Publication number
ZA200307507B
ZA200307507B ZA200307507A ZA200307507A ZA200307507B ZA 200307507 B ZA200307507 B ZA 200307507B ZA 200307507 A ZA200307507 A ZA 200307507A ZA 200307507 A ZA200307507 A ZA 200307507A ZA 200307507 B ZA200307507 B ZA 200307507B
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ZA
South Africa
Prior art keywords
methyl
hydrogen
disorder
phenoxy
compounds
Prior art date
Application number
ZA200307507A
Other languages
English (en)
Inventor
Adam Mavis Diane
Andrews Mark David
Gymer Geoffrey Edward
David Hepworth
Howard Harry Ralph Jr
Middleton Donald Stuart
Alan Stobie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA200307507B publication Critical patent/ZA200307507B/en

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200307507A 2001-04-11 2003-09-26 Phenyl heterocyclyl ether derivatives as serotonin re-uptake inhibitors. ZA200307507B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0109103.2A GB0109103D0 (en) 2001-04-11 2001-04-11 Novel compounds

Publications (1)

Publication Number Publication Date
ZA200307507B true ZA200307507B (en) 2004-11-19

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ID=9912700

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200307507A ZA200307507B (en) 2001-04-11 2003-09-26 Phenyl heterocyclyl ether derivatives as serotonin re-uptake inhibitors.

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EP (1) EP1377550B9 (uk)
JP (1) JP2005504728A (uk)
KR (1) KR100570376B1 (uk)
CN (1) CN1656072A (uk)
AP (1) AP1543A (uk)
AR (1) AR035818A1 (uk)
AT (1) ATE281435T1 (uk)
AU (1) AU2002244898B2 (uk)
BG (1) BG108204A (uk)
BR (1) BR0208812A (uk)
CA (1) CA2443699A1 (uk)
CZ (1) CZ20032677A3 (uk)
DE (1) DE60201819T2 (uk)
DO (1) DOP2002000371A (uk)
EA (1) EA008936B1 (uk)
EC (1) ECSP034802A (uk)
EE (1) EE200300498A (uk)
ES (1) ES2227448T3 (uk)
GB (1) GB0109103D0 (uk)
GE (1) GEP20053590B (uk)
GT (1) GT200200071A (uk)
HR (1) HRP20030824A2 (uk)
HU (1) HUP0303880A2 (uk)
IL (2) IL158141A0 (uk)
IS (1) IS6960A (uk)
MA (1) MA27010A1 (uk)
MX (1) MXPA03009383A (uk)
MY (1) MY136262A (uk)
NO (1) NO20034525L (uk)
NZ (1) NZ528481A (uk)
OA (1) OA12500A (uk)
PA (1) PA8543701A1 (uk)
PE (1) PE20021003A1 (uk)
PL (1) PL373533A1 (uk)
PT (1) PT1377550E (uk)
RS (1) RS79703A (uk)
SI (1) SI1377550T1 (uk)
SK (1) SK12452003A3 (uk)
SV (1) SV2003000981A (uk)
TN (1) TNSN03090A1 (uk)
UA (1) UA74430C2 (uk)
UY (1) UY27250A1 (uk)
WO (1) WO2002083643A1 (uk)
ZA (1) ZA200307507B (uk)

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AU2002256085A1 (en) * 2001-04-06 2002-10-21 Smithkline Beecham Corporation Quinoline inhibitors of hyak1 and hyak3 kinases
MXPA05003093A (es) * 2002-09-19 2005-07-13 Lilly Co Eli Diaril eteres como antagonistas de receptor opiode.
GB0318706D0 (en) * 2003-08-08 2003-09-10 Pfizer Ltd Selective serotonin reuptake inhibitors in the treatment of disease
WO2006008635A1 (en) * 2004-07-14 2006-01-26 Pfizer Limited Process for the preparation of a 3-phenoxy-pyridine derivative
NZ564759A (en) 2005-06-30 2011-08-26 Prosidion Ltd GPCR agonists
WO2007095602A2 (en) 2006-02-15 2007-08-23 Abbott Laboratories Novel acetyl-coa carboxylase (acc) inhibitors and their use in diabetes, obesity and metabolic syndrome
WO2008079610A2 (en) * 2006-12-21 2008-07-03 Abbott Laboratories Novel acetyl-coa carboxylase (acc) inhibitors and their use in diabetes, obesity and metabolic syndrome
PL2114933T3 (pl) 2007-01-04 2012-02-29 Prosidion Ltd Piperydyny jako agoniści GPCR
DE102008053242A1 (de) 2008-10-25 2010-05-06 Saltigo Gmbh Heteroaryl-Arylether
JP2014001199A (ja) * 2012-01-25 2014-01-09 Ishihara Sangyo Kaisha Ltd 有害生物防除剤
ES2927675T3 (es) 2013-03-13 2022-11-10 Jazz Pharmaceuticals Ireland Ltd Tratamiento de la cataplexia
EP2974729A1 (en) * 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases
EP3669873A1 (en) 2018-12-20 2020-06-24 Abivax Quinoline derivatives for use ine the traeatment of inflammation diseases
EP3936192B1 (en) 2019-03-06 2025-04-09 Daiichi Sankyo Company, Limited Pyrrolopyrazole derivative

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AU763884B2 (en) * 1999-02-23 2003-07-31 Pfizer Products Inc. Monoamine reuptake inhibitors for treatment of CNS disorders
BR0010783A (pt) * 1999-05-21 2002-04-09 Biovitrum Ab Novos compostos, seu uso e preparação
HUP0203448A3 (en) * 1999-10-13 2005-07-28 Pfizer Prod Inc Biaryl ether derivatives useful as monoamine reuptake inhibitors and pharmaceutical compositions containing them

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EP1377550B9 (en) 2005-11-23
EA200300988A1 (ru) 2004-04-29
GEP20053590B (en) 2005-07-25
NZ528481A (en) 2006-02-24
AP1543A (en) 2006-01-11
AP2002002468A0 (en) 2002-06-30
PE20021003A1 (es) 2002-11-12
PT1377550E (pt) 2005-01-31
GT200200071A (es) 2003-01-31
IS6960A (is) 2003-09-18
EE200300498A (et) 2004-02-16
DE60201819D1 (en) 2004-12-09
CN1656072A (zh) 2005-08-17
EP1377550A1 (en) 2004-01-07
NO20034525L (no) 2003-12-08
KR20030088133A (ko) 2003-11-17
DE60201819T2 (de) 2005-11-03
IL158141A0 (en) 2004-03-28
KR100570376B1 (ko) 2006-04-11
OA12500A (en) 2006-05-24
RS79703A (en) 2006-12-15
WO2002083643A1 (en) 2002-10-24
EP1377550B1 (en) 2004-11-03
IL158141A (en) 2007-10-31
CZ20032677A3 (cs) 2004-06-16
PA8543701A1 (es) 2004-05-26
BR0208812A (pt) 2004-03-09
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