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IL158141A0 - Phenyl heterocyclyl ether derivatives as serotonin reuptake inhibitors - Google Patents

Phenyl heterocyclyl ether derivatives as serotonin reuptake inhibitors

Info

Publication number
IL158141A0
IL158141A0 IL15814102A IL15814102A IL158141A0 IL 158141 A0 IL158141 A0 IL 158141A0 IL 15814102 A IL15814102 A IL 15814102A IL 15814102 A IL15814102 A IL 15814102A IL 158141 A0 IL158141 A0 IL 158141A0
Authority
IL
Israel
Prior art keywords
serotonin reuptake
reuptake inhibitors
ether derivatives
phenyl heterocyclyl
phenyl
Prior art date
Application number
IL15814102A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL158141A0 publication Critical patent/IL158141A0/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
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    • A—HUMAN NECESSITIES
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    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL15814102A 2001-04-11 2002-03-27 Phenyl heterocyclyl ether derivatives as serotonin reuptake inhibitors IL158141A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0109103.2A GB0109103D0 (en) 2001-04-11 2001-04-11 Novel compounds
PCT/IB2002/001032 WO2002083643A1 (en) 2001-04-11 2002-03-27 Phenyl heterocyclyl ether derivatives as serotonin re-uptake inhibitors

Publications (1)

Publication Number Publication Date
IL158141A0 true IL158141A0 (en) 2004-03-28

Family

ID=9912700

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15814102A IL158141A0 (en) 2001-04-11 2002-03-27 Phenyl heterocyclyl ether derivatives as serotonin reuptake inhibitors
IL158141A IL158141A (en) 2001-04-11 2003-09-25 Derivatives of the tricyclic phenyl ether as inhibitors of serotonin reuptake

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL158141A IL158141A (en) 2001-04-11 2003-09-25 Derivatives of the tricyclic phenyl ether as inhibitors of serotonin reuptake

Country Status (44)

Country Link
EP (1) EP1377550B9 (uk)
JP (1) JP2005504728A (uk)
KR (1) KR100570376B1 (uk)
CN (1) CN1656072A (uk)
AP (1) AP1543A (uk)
AR (1) AR035818A1 (uk)
AT (1) ATE281435T1 (uk)
AU (1) AU2002244898B2 (uk)
BG (1) BG108204A (uk)
BR (1) BR0208812A (uk)
CA (1) CA2443699A1 (uk)
CZ (1) CZ20032677A3 (uk)
DE (1) DE60201819T2 (uk)
DO (1) DOP2002000371A (uk)
EA (1) EA008936B1 (uk)
EC (1) ECSP034802A (uk)
EE (1) EE200300498A (uk)
ES (1) ES2227448T3 (uk)
GB (1) GB0109103D0 (uk)
GE (1) GEP20053590B (uk)
GT (1) GT200200071A (uk)
HR (1) HRP20030824A2 (uk)
HU (1) HUP0303880A2 (uk)
IL (2) IL158141A0 (uk)
IS (1) IS6960A (uk)
MA (1) MA27010A1 (uk)
MX (1) MXPA03009383A (uk)
MY (1) MY136262A (uk)
NO (1) NO20034525L (uk)
NZ (1) NZ528481A (uk)
OA (1) OA12500A (uk)
PA (1) PA8543701A1 (uk)
PE (1) PE20021003A1 (uk)
PL (1) PL373533A1 (uk)
PT (1) PT1377550E (uk)
RS (1) RS79703A (uk)
SI (1) SI1377550T1 (uk)
SK (1) SK12452003A3 (uk)
SV (1) SV2003000981A (uk)
TN (1) TNSN03090A1 (uk)
UA (1) UA74430C2 (uk)
UY (1) UY27250A1 (uk)
WO (1) WO2002083643A1 (uk)
ZA (1) ZA200307507B (uk)

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EP1372654A4 (en) * 2001-04-06 2007-10-03 Smithkline Beecham Corp QUINOLINE INHIBITORS OF HYAK1 AND HYAK3 KINASES
SI2208727T1 (sl) * 2002-09-19 2012-11-30 Lilly Co Eli Diaril etri kot antagonisti opioidnega receptorja
GB0318706D0 (en) * 2003-08-08 2003-09-10 Pfizer Ltd Selective serotonin reuptake inhibitors in the treatment of disease
WO2006008635A1 (en) * 2004-07-14 2006-01-26 Pfizer Limited Process for the preparation of a 3-phenoxy-pyridine derivative
CA2613235A1 (en) 2005-06-30 2007-01-11 Prosidion Limited Gpcr agonists
CN101484433A (zh) 2006-02-15 2009-07-15 艾博特公司 新的乙酰辅酶a羧化酶(acc)抑制剂及其在糖尿病、肥胖症和代谢综合征中的应用
US7928243B2 (en) * 2006-12-21 2011-04-19 Abbott Laboratories Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
PL2114933T3 (pl) 2007-01-04 2012-02-29 Prosidion Ltd Piperydyny jako agoniści GPCR
DE102008053242A1 (de) 2008-10-25 2010-05-06 Saltigo Gmbh Heteroaryl-Arylether
JP2014001199A (ja) * 2012-01-25 2014-01-09 Ishihara Sangyo Kaisha Ltd 有害生物防除剤
CA2905457A1 (en) 2013-03-13 2014-10-09 Aerial Biopharma, Llc Treatment of cataplexy
EP2974729A1 (en) 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases
EP3669873A1 (en) 2018-12-20 2020-06-24 Abivax Quinoline derivatives for use ine the traeatment of inflammation diseases
CN113543852A (zh) 2019-03-06 2021-10-22 第一三共株式会社 吡咯并吡唑衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA004860B1 (ru) * 1999-02-23 2004-08-26 Пфайзер Продактс Инк. Ингибиторы обратного захвата моноаминов для лечения расстройств цнс
MXPA01011905A (es) * 1999-05-21 2004-03-19 Biovitrum Ab Compuestos novedosos, su uso y preparacion.
IL149105A0 (en) * 1999-10-13 2002-11-10 Pfizer Prodcts Inc Biaryl ether derivatives useful as monoamine reuptake inhibitors

Also Published As

Publication number Publication date
TNSN03090A1 (fr) 2005-12-23
ECSP034802A (es) 2003-12-01
DE60201819T2 (de) 2005-11-03
AR035818A1 (es) 2004-07-14
JP2005504728A (ja) 2005-02-17
ES2227448T3 (es) 2005-04-01
MA27010A1 (fr) 2004-12-20
PA8543701A1 (es) 2004-05-26
GEP20053590B (en) 2005-07-25
EA200300988A1 (ru) 2004-04-29
CN1656072A (zh) 2005-08-17
BG108204A (bg) 2004-12-30
MXPA03009383A (es) 2004-01-29
DE60201819D1 (en) 2004-12-09
BR0208812A (pt) 2004-03-09
ATE281435T1 (de) 2004-11-15
CZ20032677A3 (cs) 2004-06-16
EP1377550B9 (en) 2005-11-23
PE20021003A1 (es) 2002-11-12
EA008936B1 (ru) 2007-10-26
KR20030088133A (ko) 2003-11-17
EP1377550B1 (en) 2004-11-03
SI1377550T1 (en) 2005-02-28
KR100570376B1 (ko) 2006-04-11
WO2002083643A1 (en) 2002-10-24
RS79703A (en) 2006-12-15
NZ528481A (en) 2006-02-24
AP2002002468A0 (en) 2002-06-30
IS6960A (is) 2003-09-18
PL373533A1 (en) 2005-09-05
ZA200307507B (en) 2004-11-19
SK12452003A3 (sk) 2004-08-03
CA2443699A1 (en) 2002-10-24
HRP20030824A2 (en) 2005-08-31
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AU2002244898B2 (en) 2007-05-24
UY27250A1 (es) 2002-12-31
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MY136262A (en) 2008-09-30
OA12500A (en) 2006-05-24
HUP0303880A2 (hu) 2004-04-28
SV2003000981A (es) 2003-07-29
GB0109103D0 (en) 2001-05-30
UA74430C2 (uk) 2005-12-15
NO20034525D0 (no) 2003-10-09
EP1377550A1 (en) 2004-01-07
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EE200300498A (et) 2004-02-16
GT200200071A (es) 2003-01-31
IL158141A (en) 2007-10-31
AP1543A (en) 2006-01-11

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