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ZA200302771B - Process for preparing distamycin derivatives. - Google Patents

Process for preparing distamycin derivatives. Download PDF

Info

Publication number
ZA200302771B
ZA200302771B ZA200302771A ZA200302771A ZA200302771B ZA 200302771 B ZA200302771 B ZA 200302771B ZA 200302771 A ZA200302771 A ZA 200302771A ZA 200302771 A ZA200302771 A ZA 200302771A ZA 200302771 B ZA200302771 B ZA 200302771B
Authority
ZA
South Africa
Prior art keywords
formula
compound
process according
derivative
amino
Prior art date
Application number
ZA200302771A
Other languages
English (en)
Inventor
Francesco Caldarelli
Lucio Ceriani
Ilaria Candiani
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Publication of ZA200302771B publication Critical patent/ZA200302771B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/42—Nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
ZA200302771A 2000-11-28 2001-11-07 Process for preparing distamycin derivatives. ZA200302771B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0029004.9A GB0029004D0 (en) 2000-11-28 2000-11-28 Process for preparing distamycin derivatives

Publications (1)

Publication Number Publication Date
ZA200302771B true ZA200302771B (en) 2004-04-13

Family

ID=9904031

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200302771A ZA200302771B (en) 2000-11-28 2001-11-07 Process for preparing distamycin derivatives.

Country Status (30)

Country Link
US (1) US6906199B2 (ru)
EP (1) EP1347958B1 (ru)
JP (1) JP4574944B2 (ru)
KR (1) KR100847234B1 (ru)
CN (1) CN1190418C (ru)
AR (1) AR035073A1 (ru)
AT (1) ATE287395T1 (ru)
AU (2) AU2069602A (ru)
BR (1) BR0115351A (ru)
CA (1) CA2427177C (ru)
CZ (1) CZ303461B6 (ru)
DE (1) DE60108528T2 (ru)
EA (1) EA005399B1 (ru)
EE (1) EE05218B1 (ru)
ES (1) ES2236365T3 (ru)
GB (1) GB0029004D0 (ru)
HU (1) HU229670B1 (ru)
IL (2) IL155385A0 (ru)
MX (1) MXPA03004679A (ru)
MY (1) MY134563A (ru)
NO (1) NO324601B1 (ru)
NZ (1) NZ525230A (ru)
PE (1) PE20020551A1 (ru)
PL (1) PL205821B1 (ru)
PT (1) PT1347958E (ru)
SI (1) SI1347958T1 (ru)
SK (1) SK286610B6 (ru)
TW (1) TWI287002B (ru)
WO (1) WO2002044147A1 (ru)
ZA (1) ZA200302771B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100842363B1 (ko) * 2007-04-05 2008-07-02 김춘동 튜브 짜개
KR102233537B1 (ko) * 2013-03-15 2021-03-29 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 항균성 폴리아미드 조성물 및 유방염 치료
JP2015080906A (ja) * 2013-10-23 2015-04-27 セイコーエプソン株式会社 液体収容容器、液体噴射装置
JPWO2023149487A1 (ru) * 2022-02-02 2023-08-10

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8612218D0 (en) 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents
AU605512B2 (en) 1986-10-07 1991-01-17 Boehringer Mannheim Italia S.P.A. Pharmaceutical compositions having antineoplastic activity
GB8906709D0 (en) 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
JP2919867B2 (ja) 1989-09-27 1999-07-19 千寿製薬株式会社 抗腫瘍剤
IT1272234B (it) 1994-05-02 1997-06-16 Consiglio Nazionale Ricerche Derivati glutationici delle antracicline e procedimento per ottenerli.
GB9416005D0 (en) 1994-08-08 1994-09-28 Erba Carlo Spa Peptidic compounds analogous to distamycin a and process for their preparation
US5880097A (en) 1996-01-04 1999-03-09 Terrapin Techologies, Inc. Tethered prodrugs
GB9610079D0 (en) 1996-05-14 1996-07-17 Pharmacia Spa Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents
KR100469778B1 (ko) * 1996-05-14 2005-05-16 파머시아 앤 업잔 에스.피.에이. 디스타마이신유도체,이의제조방법,및항종양성및항바이러스성제제로서의이들의용도
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9623522D0 (en) 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9727524D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Synergistic antitumor composition containing a biologically active ureido compound
GB9806689D0 (en) 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents
GB9806692D0 (en) 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents
GB9816653D0 (en) 1998-07-30 1998-09-30 Pharmacia & Upjohn Spa Oxidised sulfurated distamycin derivatives process for preparing them and their use as antitumor agents
GB9816652D0 (en) 1998-07-30 1998-09-30 Pharmacia & Upjohn Spa Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents

Also Published As

Publication number Publication date
MXPA03004679A (es) 2003-09-05
AU2069602A (en) 2002-06-11
NO20032297L (no) 2003-05-21
PL205821B1 (pl) 2010-05-31
SK286610B6 (sk) 2009-02-05
NZ525230A (en) 2004-06-25
PE20020551A1 (es) 2002-06-12
EP1347958A1 (en) 2003-10-01
AU2002220696B2 (en) 2006-11-30
DE60108528T2 (de) 2006-03-23
PL362179A1 (en) 2004-10-18
EE200300204A (et) 2003-08-15
GB0029004D0 (en) 2001-01-10
NO20032297D0 (no) 2003-05-21
DE60108528D1 (de) 2005-02-24
CN1190418C (zh) 2005-02-23
US6906199B2 (en) 2005-06-14
JP2004517830A (ja) 2004-06-17
BR0115351A (pt) 2003-08-26
EE05218B1 (et) 2009-10-15
WO2002044147A1 (en) 2002-06-06
JP4574944B2 (ja) 2010-11-04
AR035073A1 (es) 2004-04-14
HUP0302158A2 (hu) 2003-09-29
HK1060732A1 (en) 2004-08-20
NO324601B1 (no) 2007-11-26
ES2236365T3 (es) 2005-07-16
SK8322003A3 (en) 2003-10-07
HU229670B1 (en) 2014-04-28
KR20030066681A (ko) 2003-08-09
IL155385A (en) 2009-02-11
SI1347958T1 (ru) 2005-08-31
CA2427177A1 (en) 2002-06-06
CA2427177C (en) 2010-01-19
CZ303461B6 (cs) 2012-09-26
US20040077550A1 (en) 2004-04-22
IL155385A0 (en) 2003-11-23
CZ20031132A3 (cs) 2003-08-13
KR100847234B1 (ko) 2008-07-18
TWI287002B (en) 2007-09-21
PT1347958E (pt) 2005-05-31
EP1347958B1 (en) 2005-01-19
ATE287395T1 (de) 2005-02-15
EA005399B1 (ru) 2005-02-24
CN1476431A (zh) 2004-02-18
EA200300617A1 (ru) 2003-10-30
MY134563A (en) 2007-12-31

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