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YU48665B - Postupak za proizvodnju stabilnih tableta i granulata, koji kao aktivnu materiju sadrže natrijum-2-merkaptoetansulfonat (mesna) - Google Patents

Postupak za proizvodnju stabilnih tableta i granulata, koji kao aktivnu materiju sadrže natrijum-2-merkaptoetansulfonat (mesna)

Info

Publication number
YU48665B
YU48665B YU122691A YU122691A YU48665B YU 48665 B YU48665 B YU 48665B YU 122691 A YU122691 A YU 122691A YU 122691 A YU122691 A YU 122691A YU 48665 B YU48665 B YU 48665B
Authority
YU
Yugoslavia
Prior art keywords
weight
parts
effervescent
tablets
binder
Prior art date
Application number
YU122691A
Other languages
English (en)
Other versions
YU122691A (sh
Inventor
Dieter Sauerbier
Jurgen Engel
Eckhard Milsmann
Original Assignee
Baxter Healthcare S.A.
Baxter International Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare S.A., Baxter International Inc. filed Critical Baxter Healthcare S.A.
Priority to SI9111226A priority Critical patent/SI9111226A/sl
Priority to HRP-1226/91A priority patent/HRP920889B1/xx
Publication of YU122691A publication Critical patent/YU122691A/sh
Publication of YU48665B publication Critical patent/YU48665B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Seasonings (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

Postupak za proizvodnju stabilnih tableta, koje kao aktivnu materiju sadrže Mesnu, natrijum-2-merkaptoetansulfonat i eventualno uobičajene materije za ukus, slatkoću i aromu kao i 0,01 - 1 masenih delova vezivnog sredstva 0,03 - 0,4 masenih delova sredstva za razlaganje 0,01 - 0,2 masenih delova sredstva za klizanje 0,1 - 1 masenih delova punioca u odnosu na 1 maseni deo Mesne, a u slučaju šumeće tablete još dodatno sadrže 0,05 - 30 masenih delova neke uobičajene fiziološki neškodljive šumeće mešavine, naznačen time, što se Mesna najpre sa jednim C1-C4-alkoholom ili acetonom ili mešavinom navedenih organskih materija sa vodom i jednim puniocem kao i vezivnim sredstvom, a eventualno takođe i sa jednim sredstvom za razlaganje, a u slučaju šumeće tablete i sa jednom šumećom tabletom koja otpušta CO2 granulira, pri čemu se navedene pomoćne materije upotrebljavaju u količinama, koje se odnose na jedan maseni deo Mesne ili se pak dodaje samo jedan deo ukupne količine ovih materija, a ostatak se dodaje nakon granuliranja, što se zatim tako dobijeni granulat suši, a zatim se dodaje sredstvo za klizanje odnosno u slučaju šumeće tablete organska kiselina šumeće mešavine ili celokupna šumeća mešavina, a po potrebi i ostatak vezivnog sredstva, punioca i sredstva za razlaganje i uobičajene materije za ukus, slatkoću i aromu, posle čega se sve ovo homogenizuje i najzad presuje u tablete, a eventualno se tako dobijene tablete presvlače glazurom. - Prijava sadrži još 1 zavisni zahtev.
YU122691A 1990-07-16 1991-07-12 Postupak za proizvodnju stabilnih tableta i granulata, koji kao aktivnu materiju sadrže natrijum-2-merkaptoetansulfonat (mesna) YU48665B (sh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI9111226A SI9111226A (en) 1990-07-16 1991-07-12 Tabletes and granulate containing Mesna as an active agent
HRP-1226/91A HRP920889B1 (en) 1990-07-16 1992-10-02 Tablet and granulate containing mesna as active agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4022525 1990-07-16

Publications (2)

Publication Number Publication Date
YU122691A YU122691A (sh) 1994-01-20
YU48665B true YU48665B (sh) 1999-06-15

Family

ID=25895028

Family Applications (1)

Application Number Title Priority Date Filing Date
YU122691A YU48665B (sh) 1990-07-16 1991-07-12 Postupak za proizvodnju stabilnih tableta i granulata, koji kao aktivnu materiju sadrže natrijum-2-merkaptoetansulfonat (mesna)

Country Status (3)

Country Link
US (1) US5358718A (sh)
UA (1) UA26305A (sh)
YU (1) YU48665B (sh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
DE19826517B4 (de) * 1998-06-15 2006-03-23 Baxter Healthcare S.A. Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette
CA2936748C (en) 2014-10-31 2017-08-08 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
GB2595203A (en) 2020-03-03 2021-11-24 Alkaloid Ad Skopje Formulation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1185551B (it) * 1985-04-15 1987-11-12 Schering Spa Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione

Also Published As

Publication number Publication date
YU122691A (sh) 1994-01-20
UA26305A (uk) 1999-08-30
US5358718A (en) 1994-10-25

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