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YU14493A - Sulfonamidokarboksiamidi - Google Patents

Sulfonamidokarboksiamidi

Info

Publication number
YU14493A
YU14493A YU14493A YU14493A YU14493A YU 14493 A YU14493 A YU 14493A YU 14493 A YU14493 A YU 14493A YU 14493 A YU14493 A YU 14493A YU 14493 A YU14493 A YU 14493A
Authority
YU
Yugoslavia
Prior art keywords
group
denotes
formula
alkyl
ch2ch
Prior art date
Application number
YU14493A
Other languages
English (en)
Inventor
J. Ackermann
D. Banner
K. Gubernator
K. Hillpert
G. Schmid
Original Assignee
F. Hoffmann - La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann - La Roche Ag. filed Critical F. Hoffmann - La Roche Ag.
Publication of YU14493A publication Critical patent/YU14493A/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SULFONAMIDOKARBOKSIAMIDI, novi sulfonamidokarboksamidi formule u kojoj označavaju A aril, heteroaril, heterociklil, alkil ili cikloalkil, M grupu formule M1, ili, ako X oznaCava grupu X2, ili X oznaCava grupu X1 najmanje jedan od simbola R1, R2 i Q a Q je različit od H, i/ili ako A označava alkil ili cikloalkil, onda M takođe može da označava grupu jedne od formula M2 do M8, CH2CH(NH(CO)i.2R7)- (M3) -CH2CH(NHC(0)0-benzil)r (M4) =CH(CH2)i-2R7 (M3) =CHCH2C(0)R8 (M6) =CHCH2NH(CO)i.2R7 (M7) =CHĆH2NHC(0)0-benzU (M8) Q H, niži alldl ili niži alkU (OH, COOH ili COO-niži alkil), X grupu formule X1 ili X2. Y H ili, ako X označava grupu X2 ili ako X označava X1, u kojoj je najmanje jedan od simbola R1 i R2 različit od H, onda Y takođe može da označava CH2COOH ili SO2-A', kao i njihovi hidrati ili solvati sprečavaju agregaciju krvnih pločica koja je indukovana trombinom i zgrušavanje fibrinogena u krvnoj plazmi. Oni se dobivaju amidiniranjem ciklične amino grupe koja stoji na mestu grupe X ili stvaranjem amida C(0)N(Q).
YU14493A 1992-03-06 1993-03-03 Sulfonamidokarboksiamidi YU14493A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH72892 1992-03-06

Publications (1)

Publication Number Publication Date
YU14493A true YU14493A (sh) 1997-01-08

Family

ID=4193803

Family Applications (1)

Application Number Title Priority Date Filing Date
YU14493A YU14493A (sh) 1992-03-06 1993-03-03 Sulfonamidokarboksiamidi

Country Status (10)

Country Link
KR (1) KR100274422B1 (sh)
BR (1) BR9300753A (sh)
HR (1) HRP930266A2 (sh)
MX (1) MX9301155A (sh)
PL (1) PL173030B1 (sh)
SG (1) SG48063A1 (sh)
SI (1) SI9300104A (sh)
SK (1) SK14893A3 (sh)
YU (1) YU14493A (sh)
ZA (1) ZA931403B (sh)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201303B (sh) * 1990-07-05 1993-03-01 Hoffmann La Roche

Also Published As

Publication number Publication date
KR100274422B1 (ko) 2000-12-15
ZA931403B (en) 1993-09-06
PL297960A1 (en) 1993-09-20
BR9300753A (pt) 1993-09-08
SI9300104A (en) 1993-09-30
MX9301155A (es) 1993-09-01
KR930019627A (ko) 1993-10-18
SG48063A1 (en) 1998-04-17
SK14893A3 (en) 1993-11-10
HRP930266A2 (en) 1996-04-30
PL173030B1 (pl) 1998-01-30

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