[go: up one dir, main page]

WO2023193445A1 - 一种多联排检测装置的制造方法 - Google Patents

一种多联排检测装置的制造方法 Download PDF

Info

Publication number
WO2023193445A1
WO2023193445A1 PCT/CN2022/132929 CN2022132929W WO2023193445A1 WO 2023193445 A1 WO2023193445 A1 WO 2023193445A1 CN 2022132929 W CN2022132929 W CN 2022132929W WO 2023193445 A1 WO2023193445 A1 WO 2023193445A1
Authority
WO
WIPO (PCT)
Prior art keywords
tape
detection device
completely
bottom cassette
rectangular
Prior art date
Application number
PCT/CN2022/132929
Other languages
English (en)
French (fr)
Inventor
王春明
商涛
崔超
凌云
李天昊
Original Assignee
艾康生物技术(杭州)有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 艾康生物技术(杭州)有限公司 filed Critical 艾康生物技术(杭州)有限公司
Priority to US18/850,061 priority Critical patent/US20250214077A1/en
Priority to EP22871049.7A priority patent/EP4286120A4/en
Publication of WO2023193445A1 publication Critical patent/WO2023193445A1/zh

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/527—Tear-lines for separating a package into individual packages
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E10/00—Energy generation through renewable energy sources
    • Y02E10/50—Photovoltaic [PV] energy

Definitions

  • the present invention relates to a manufacturing method of a detection device, and in particular, to a manufacturing method of a multi-row detection device suitable for adopting a highly automated production process.
  • this type of test kit 1 generally includes an upper cover 2, a bottom plate 3 and a test strip 4.
  • the upper cover 2 and the bottom plate 3 are combined by buckling, welding, glue bonding, etc., and the test
  • the strip 4 is placed on the base plate 3 and between the upper cover 2 and the base plate 3 .
  • the upper cover 2 includes a sampling hole 5 and an observation hole 6 .
  • the liquid sample for detection is applied to the test strip 4 through the sampling hole 5. After the detection is completed, the color change on the test strip 4 is observed through the observation hole 6, and the detection result is determined accordingly.
  • the upper cover 2 and bottom plate 3 of this type of detection kit shown in Figures 1 and 2 are made of thermo-injection molded hard plastic plates, which account for a relatively large cost of the entire detection kit. Both the upper cover and the bottom plate have a certain height and width. After the two are combined, additional aluminum foil bags need to be used for sealing and packaging, making the entire detection kit 1 larger in volume, much larger than the test strip 4, which increases storage costs. And transportation costs also increase the production process, thereby increasing production costs. In addition, plastics take a long time to degrade, and using large amounts of plastics is not in line with the concept of environmental protection. Furthermore, this type of test kit is not suitable for manufacturing with highly automated production processes and equipment, but requires a large number of workers for manual assembly. The assembly process is boring and cumbersome. Long-term operations are prone to fatigue and burnout, and are prone to errors. The product qualification rate is reduced and labor costs are increased.
  • the object of the present invention is to provide a manufacturing method for a multi-row detection device that can easily realize automated production.
  • the manufacturing method has a high degree of automation, requires a small number of workers, has low labor intensity, and produces products that are small in size and have low production costs. , packaging and transportation costs are low, and less plastic materials are used, which is very environmentally friendly.
  • the present invention provides a manufacturing method of a multi-row detection device, which method includes the following steps:
  • the first hob is provided with several linear cutters on its cylindrical outer surface.
  • the linear cutters are connected to the cylindrical outer surface.
  • the axis of the surface is parallel and equidistant from the axis of the cylindrical outer surface, and the plurality of linear cutters are equidistantly arranged on the cylindrical outer surface of the first hob;
  • E. Use a cylindrical second hob to cut the sealing film tape and the bottom cassette tape to form an incompletely disconnected cutting line and a completely disconnected cutting line.
  • the incompletely disconnected cutting line causes the two adjacent detection devices to be in contact with each other.
  • Connection, completely disconnected cutting lines separate two adjacent detection devices. Between each two adjacent completely disconnected cutting lines are the same number of incompletely disconnected cutting lines, forming a multi-row row. detection device.
  • a further improvement of the present invention is that an elastic material is placed in the area between two adjacent linear cutters of the first hob, and the tips of the linear cutters exceed the elastic material by an appropriate distance.
  • a further improvement of the present invention is that the second hob is provided with a plurality of first rectangular cutters and second rectangular cutters at equal intervals on its cylindrical outer surface, and there are an equal number of second rectangular cutters between each two adjacent second hobs.
  • first rectangular cutters the long sides of the first rectangular cutter and the second rectangular cutter are parallel to the axis of the cylindrical outer surface; the first rectangular cutter forms two cutting lines that are not completely disconnected, and the second The rectangular cutter creates one incompletely broken cutting line and one completely broken cutting line.
  • a further improvement of the present invention is that the two long sides of the first rectangular cutter arranged on the cylindrical outer surface of the second hob are zigzag blades, and the zigzag blades form a cutting line that is not completely broken.
  • a further improvement of the present invention is that the zigzag blade provided on the cylindrical outer surface of the second hob can completely cut off the sealing film tape, but does not completely cut off the bottom cassette tape or does not cut the bottom cassette tape.
  • a further improvement of the present invention is that one long side of the second rectangular cutter arranged on the cylindrical outer surface of the second hob is a straight blade, and the other long side is a zigzag blade, and the straight blade forms a completely broken Cutting line, a zigzag blade creates a cutting line that is not completely broken.
  • a further improvement of the present invention is that: the linear blade of the second rectangular cutter completely cuts off both the sealing tape and the bottom cassette tape; the zigzag blade of the second rectangular cutter completely cuts off the sealing tape but does not completely cut off the bottom cassette tape; or Do not cut the bottom cassette.
  • a further improvement of the present invention is that the thickness of the bottom cassette tape is between 0.2 mm and 1.5 mm, and the thickness of the sealing film tape is between 0.02 mm and 0.1 mm.
  • the manufacturing method of the multi-row detection device of the present invention has a high degree of automation, high production efficiency, a small number of workers required, low labor intensity, and the products produced are small in size, so the production, packaging and transportation costs are lower than those of the existing technology. Much. Products manufactured using the invention do not need to use additional aluminum foil bags for sealing packaging, which reduces process steps, saves costs, and reduces product prices. In addition, the products manufactured using the invention are small in size, easy to carry, convenient to operate and low in price.
  • the present invention uses the same zigzag blade in the area where the incompletely broken cutting line is formed to completely cut off the sealing film tape without completely cutting off the bottom cassette tape at the same position and in one cutting step, thus greatly improving the efficiency of cutting. improve production efficiency.
  • Figure 1 is a three-dimensional exploded view of an existing detection kit
  • Figure 2 is a three-dimensional schematic diagram of the combination of Figure 1;
  • Figure 3 is a schematic diagram of step B of the manufacturing method of the multi-row detection device of the present invention.
  • Figure 4 is a partial enlarged schematic view of the portion of the cylindrical first hob shown in Figure 3 within circle A;
  • Figure 5 is a schematic diagram of step D of the manufacturing method of the multi-row detection device of the present invention.
  • Figure 6 is a schematic diagram of step E of the manufacturing method of the multi-row detection device of the present invention.
  • Figure 7 is a partially enlarged schematic diagram of the portion within circle B in Figure 6;
  • Figure 8 is an enlarged top view of the first rectangular cutter on the cylindrical second hob used in Figure 6;
  • Figure 9 is a schematic cross-sectional view along line A-A of Figure 8.
  • Figure 10 is an enlarged top view of the second rectangular cutter on the cylindrical second hob used in Figure 6;
  • Figure 11 is a schematic cross-sectional view along line B-B of Figure 10;
  • Figure 12 is a top view of a multi-row detection device produced using the manufacturing method of the present invention (the dotted line indicates the blocked part);
  • Figure 13 is a schematic cross-sectional view along line C-C of Figure 12;
  • Figure 14 is a partially enlarged schematic diagram of the portion within circle C in Figure 13;
  • FIG. 15 is a top view of a single detection device torn off from the multi-row detection device of FIG. 12 .
  • Figure 16 is a schematic diagram of multiple multi-row detection devices produced by the manufacturing method of the present invention arranged side by side.
  • FIG. 17 is a partially enlarged schematic diagram of the portion within circle D in FIG. 16 .
  • Figure 18 is a plan view of the first rectangular cutter and the second rectangular cutter on the second hob after being expanded.
  • Figure 19 is an enlarged view of the portion within circle "E" in Figure 18.
  • Fig. 20 is a modified example of Fig. 19.
  • the manufacturing method of a multi-row detection device of the present invention includes the following steps: A. Provide a bottom cassette 603, a test strip 604 and a sealing film tape 608. The thickness of the bottom cassette 603 is Greater than the thickness of the sealing tape 608; B. As shown in Figure 3, a cylindrical first hob 605 is used to cooperate with a cylindrical pad wheel 605' to cut the test strip 604 into several test strips 606 arranged side by side. , wherein the first hob 605 is provided with a plurality of linear blades 607 with a sheet-like structure on its cylindrical outer surface. The blades of the linear blades 607 are parallel to the axis of the cylindrical outer surface and the distance between them and the axis of the cylindrical outer surface.
  • place the cut test strip 606 on the bottom cassette 603 in sequence for example, using a mechanical arm to grab or a negative pressure suction cup to absorb The film on the upper surface of the test strip, manual placement of the test strip, etc., make the two adjacent test strips 606 equally spaced from each other by a preset distance and adhere to the preset position on the bottom cassette; D.
  • the open cutting line 613 and the incompletely disconnected cutting line 612 connect two adjacent detection devices 614.
  • the completely disconnected cutting line 613 separates the two adjacent detection devices 614, and each two adjacent ones are completely disconnected. Between the cutting lines 613 are the same number of cutting lines 612 that are not completely disconnected, thereby forming a multi-row detection device 501 (as shown in Figures 12, 13, 16 and 17).
  • the second hob 611 is provided with several rectangular cutters at equal intervals on its cylindrical outer surface.
  • These rectangular cutters include a first rectangular cutter 615 and a second rectangular cutter 615', and each An equal number of first rectangular cutters 615 are arranged between two adjacent second rectangular cutters 615'.
  • the long sides of the first rectangular cutter 615 and the second rectangular cutter 615' are both parallel to the axis of the cylindrical outer surface and the distance from the edge of the long side to the axis of the cylindrical outer surface is equal.
  • a completely disconnected cutting line 613 is formed by the second rectangular cutter 615', and the multiple detection devices 614 between the two completely disconnected cutting lines 613 form a multi-row detection device 501.
  • the first rectangular cutter 615 forms a cutting line 612 that is not completely broken, so that the individual detection devices 614 in the multi-row detection device 501 are easily separated.
  • N first rectangular cutters 615 between two adjacent second rectangular cutters 615' a multi-row detection device 501 with N+1 single detection devices 614 is formed.
  • there are four first rectangular cutters 615 between two adjacent second rectangular cutters 615' and the finally formed multi-row detection device has five single detection devices.
  • FIG. 16 between every two adjacent completely disconnected cutting lines 613 (represented by solid lines in FIG. 16 ) are four incompletely disconnected cutting lines 612 (represented by dotted lines in FIG. 16 ). express).
  • Figure 18 is a plan view of the first rectangular cutter and the second rectangular cutter on the second hob after unfolding, showing the arrangement of the first rectangular cutter and the second rectangular cutter.
  • two adjacent rectangular cutters may share a long side 617 or 617' (as shown in Figure 19).
  • two adjacent rectangular cutters are completely independent and do not share one long side, but each has two long sides. side 617 or 617', and leave an appropriate gap between the two adjacent long sides (as shown in Figure 20).
  • An elastic material 618 is placed in the area between two adjacent linear blades 607 of the first hob 605 .
  • the tips of the linear blades 607 extend beyond the elastic material 618 by an appropriate distance. This appropriate distance is less than the thickness of the test strip 606, ensuring that the test strip compresses into the elastic material when cut.
  • the elastic material 618 is preferably rubber, foam, high-density sponge, silicone, latex, etc.
  • the advantage of placing the elastic material 618 in the area between two adjacent linear blades 607 is: when the linear blade 607 is cutting the test strip 604, the elastic material 618 is compressed by the cut test strip 606, so the cut is deeper; After the blade 607 leaves the cut test strip 606, the elastic material 618 returns to its original position and pushes the test strip 606 out. This solves the problem of the test strip 606 being stuck between two adjacent straight blades 607 and making it difficult to come out easily. question.
  • the two long sides 616 of the first rectangular cutter 615 disposed on the cylindrical outer surface of the second hob 611 are zigzag blades 617, which are not completely broken.
  • the cutting line 612 (as shown in Figure 7), that is, the cutting line 612 that is not completely disconnected includes the following two technical solutions: a. Completely cutting off the sealing film tape 608 and partially cutting the bottom cassette tape 603 (easy to separate a single Separation of the detection device); b. Completely cut off the sealing film tape 608 and the bottom cassette 603 is not cut (used to only separate the sealing film tape of a single detection device for detection).
  • the teeth 619 of the zigzag blade 617 penetrate the sealing film tape 608 and the bottom tape 603 in the area between two adjacent adhesive tapes 610, thereby disconnecting the two adjacent adhesive tapes 610 in this area.
  • This has the advantage of reducing the resistance to tearing the cutting line 612 that is not completely broken.
  • the zigzag blade 617 only completely cuts off the sealing tapes at the two adhesive tapes 610 through the blade at the bottom of the recess 620 to form a completely disconnected cut 508 (as shown in Figure 14) without cutting the bottom tape, or completely cutting off the sealing tape.
  • the film tape is then further cut off part of the bottom cassette located below the sealing film tape (including continuous or spaced cutting of part of the depth of the upper part of the bottom cassette but not penetrating to the bottom surface of the bottom cassette, forming an incompletely broken cassette as shown in Figure 7 Cutting line 612, and spaced cutting of the bottom cassette and the cutting part penetrates to the bottom surface of the bottom cassette 603, forming spaced cutting lines 507) as shown in Figure 14, forming an incompletely disconnected connection between two adjacent detection devices 614
  • the line 612 is cut, thereby forming a multi-row detection device 501 composed of several detection devices 614 .
  • a second hob as shown in Figure 20 is selected.
  • the zigzag blade 617 provided on the cylindrical outer surface of the second hob 611 completely cuts the sealing tape 608, forming a complete break on the sealing tape 608.
  • the incision 508 is made so that a gap visible to the naked eye or detectable by an instrument is formed between the cut sealing tapes (this gap is conducive to checking whether the sealing tape has been completely cut off with the naked eye or using an instrument, which helps to improve the quality of the product) rate), but the bottom cassette 603 is not completely cut off (as shown in Figure 14). That is, the bottom cassette 603 is cut at intervals, through-cuts 507 are formed in the cut areas of the bottom cassette, and connecting portions are formed in uncut areas of the bottom cassette. Furthermore, as shown in FIG.
  • the tooth portion 619 of the zigzag blade 617 provided on the cylindrical outer surface of the second hob 611 forms a through-cut 625 on the bottom cassette 603 that penetrates the bottom cassette 603 , and its recessed portion 620 Then, the bottom cassette 603 is not cut, and a connecting portion 626 spaced apart from the through-cut 625 is formed.
  • One long side of the second rectangular cutter 615' disposed on the cylindrical outer surface of the second hob 611 is a zigzag blade 617, and the other long side is a straight blade 617.
  • the zigzag blade 617 is as mentioned above, the straight blade 617' completely cuts off both the sealing tape 608 and the bottom cassette tape 603, forming a completely disconnected cutting line 613 (as shown in Figure 17 shown), that is, the side of the multi-row detection device 501, so that the multi-row detection device 501 is separated from the bottom cassette 603, becoming a product produced by using the manufacturing method of the present invention.
  • FIGs 12 and 13 show a multi-row detection device 501 produced using the manufacturing method of the present invention.
  • the multi-row detection device 501 includes ten detection devices 614 arranged side by side, with two adjacent detection devices 614 connected by non-completely disconnected cutting lines 612 .
  • Each detection device 614 is formed with an annular track-shaped adhesive strip 610 .
  • Figure 14 shows the structure of two adjacent detection devices 614 at the connection point.
  • Figure 15 shows the structure of a single detection device 614 torn from the multi-row detection device 501, where the dotted lines represent the blocked parts.
  • Figure 16 shows the planar arrangement when a multi-row detection device includes five single detection devices, especially the planar arrangement of the incompletely disconnected cutting lines 612 and the completely disconnected cutting lines 613, that is, in the phase There are four incompletely broken cutting lines 612 (shown by dotted lines in the figure) between two adjacent completely disconnected cutting lines 613 (shown by solid lines in the figure).
  • the bottom cassette 603 is preferably made of moisture-proof and oxidation-proof PE or PP material, and its thickness is preferably between 0.2 mm and 1.5 mm.
  • the sealing tape 608 is preferably made of moisture-proof and oxidation-proof PE, PP or PET material, and its thickness is preferably between 0.02 mm and 0.1 mm. Since the thickness of the bottom cassette 603 is much greater than the thickness of the sealing tape 608, the bottom cassette 603 has moderate rigidity and high strength, while the sealing tape 608 is softer and has better resistance to stretching and tearing. cracking performance, both of which are suitable for using the manufacturing method of the present invention to produce low-priced products on automated equipment.
  • FIG. 12 and FIG. 13 show that a multi-row detection device 501 includes ten detection devices 614 arranged side by side, the number of ten is variable and can also be two, five, twenty, etc. as any suitable number.
  • the number that is, the number of detection devices 614 included in the multi-row detection device produced using the manufacturing method of the present invention can be set according to actual needs.
  • the present invention uses the same zigzag blade in the area where the incompletely broken cutting line is formed to completely cut off the sealing film tape 608 without completely cutting off the bottom cassette tape 603 at the same position and in one cutting step. Greatly improve production efficiency.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Clinical Laboratory Science (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Composite Materials (AREA)
  • Plasma & Fusion (AREA)
  • Packages (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Containers And Plastic Fillers For Packaging (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)

Abstract

一种多联排检测装置的制造方法，将测试条（606）密封在封膜带（606）和底卡带（608）之间的密闭空腔（609）内，形成若干个并排排列并且两两连接的检测装置，相邻的两个检测装置由未完全断开的切割线（612）连接，该未完全断开的切割线（612）易于撕开。该结构采用包含有锯齿形刀片（617）的矩形切刀（615）切割封装，从而获得体积小，用料少的多联排检测装置，其易于实现自动化生产，减少了工人数量，降低了劳动强度，同时大大降低了生产、包装和运输成本，从而使产品的价格低廉。

Description

一种多联排检测装置的制造方法 技术领域
本发明涉及一种检测装置的制造方法，尤其是涉及一种适合采用自动化程度高的生产工艺的多联排检测装置的制造方法。
背景技术
利用尿液、血液或人体其他组织液等体液对疾病或其他生理指标进行检测的一次性检测试剂盒已在全世界普遍使用，其应用场所可以是在由专业人员操作的实验室，或在家中、学校、商场、道路卡口、海关等由非专业人员的自行操作。如图1和图2所示，此类检测试剂盒1一般包括上盖2、底板3和测试条4，其中上盖2与底板3以卡扣、焊接、胶水粘接等方式相结合，测试条4被安置在底板3上并且位于上盖2与底板3之间。上盖2包括加样孔5和观测孔6。用于检测的液体样本经由加样孔5施加到测试条4上，检测结束后，经由观测孔6观察测试条4上的颜色变化，据此来判定检测结果。
图1和图2所示的这类检测试剂盒的上盖2和底板3采用的是热注塑成型的硬质塑料板材，在整个检测试剂盒中占较大成本。上盖和底板均有一定的高度和宽度，两者结合后还需要用额外的铝箔袋进行密封包装，使得整个检测试剂盒1的体积较大，远远大于测试条4的体积，增加了仓储和运输成本，也增加了生产工艺流程，从而增加了生产成本。此外，塑料的降解时间长，大量使用塑料不符合环保理念。再者，这类检测试剂盒不适合采用自动化程度较高的生产工艺和设备制造，而需要大量的工人进行手工组装，组装过程枯燥、繁锁，长时间作业容易产生疲劳和倦怠，容易出错，降低了产品的合格率，并且增加了劳动力成本。
由于一次性使用的检测试剂盒已被广泛使用，为降低使用者的购买成本，需要尽量降低产品的价格并且提高使用的便捷性，从而提高消费者的使用意愿。特别是在流行病蔓延的情况下，如何快速推广这类检测试剂盒，让更多的人买得起并愿意使用这类快速检测试剂盒产品，是目前需要解决的问题。
本发明的目的是提供一种容易实现自动化生产的多联排检测装置的制造方法，该 制造方法自动化程度高，所需要的工人数量少，劳动强度低，并且生产的产品体积小巧，生产成本低，包装和运输成本低，并且使用的塑料材料少，非常的环保。
发明内容
为了解决上述技术问题，本发明提供了一种多联排检测装置的制造方法，该方法包括如下步骤：
A、提供底卡带、测试条带和封膜带，其中底卡带的厚度大于封膜带的厚度；
B、采用圆柱形的第一滚刀将测试条带切割成若干个并排排列的测试条，其中该第一滚刀在其圆柱形外表面设置若干把直线切刀，直线切刀与圆柱形外表面的轴线平行并且与圆柱形外表面的轴线之间的距离相等，该若干把直线切刀等间距地排列在第一滚刀的圆柱形外表面上；
C、依次将切割后的测试条放置到底卡带上，使测试条粘附在底卡带上预先设置的位置上；
D、将封膜带传输到底卡带的上方，采用热封工艺通过加热和挤压将封膜带粘接到底卡带上，并且将所述若干个测试条分别封装在封膜带和底卡带之间对应的密闭空腔内，在测试条的周围形成闭合的粘接带；
E、采用圆柱形的第二滚刀切割封膜带和底卡带，形成未完全断开的切割线和完全断开的切割线，未完全断开的切割线使相邻的两个检测装置相连接，完全断开的切割线使相邻的两个检测装置相分离，每相邻两根完全断开的切割线之间为相同数量的若干根未完全断开的切割线从而形成多联排检测装置。
本发明的进一步改进在于：在第一滚刀之相邻两把直线切刀之间区域放置有弹性材料，直线切刀的刀尖超出弹性材料适当距离。
本发明的进一步改进在于：第二滚刀在其圆柱形外表面等间距地设置若干把第一矩形切刀和第二矩形切刀，每相邻两个第二矩形切刀之间有数量相等的若干个第一矩形切刀；第一矩形切刀和第二矩形切刀的长边与圆柱形外表面的轴线平行；第一矩形切刀形成两根未完全断开的切割线，第二矩形切刀形成一根未完全断开的切割线和一根完全断开的切割线。
本发明的进一步改进在于：设置在第二滚刀之圆柱形外表面上的第一矩形切刀的两个长边为锯齿形刀片，该锯齿形刀片形成未完全断开的切割线。
本发明的进一步改进在于：设置在第二滚刀之圆柱形外表面上的锯齿形刀片将封膜带完全切断，但不将底卡带完全切断或者不切割底卡带。
本发明的进一步改进在于：设置在第二滚刀之圆柱形外表面上的第二矩形切刀的一个长边为直线刀片，另一个长边为锯齿形刀片，该直线刀片形成完全断开的切割线，锯齿形刀片形成未完全断开的切割线。
本发明的进一步改进在于：第二矩形切刀的直线刀片将封膜带和底卡带均完全切断，第二矩形切刀的锯齿形刀片将封膜带完全切断，但不将底卡带完全切断或者不切割底卡带。
本发明的进一步改进在于：底卡带的厚度介于0.2毫米至1.5毫米之间，封膜带的厚度介于0.02毫米至0.1毫米之间。
有益效果
由于本发明采用的塑料材料少，因而非常环保。本发明多联排检测装置的制造方法自动化程度高，生产效率高，所需的工人数量少，劳动强度低，并且生产的产品体积小巧，因此生产、包装和运输成本均比现有技术要低的多。运用本发明制造的产品无需额外再用铝箔袋做密封包装，减少了工艺步骤，节约了成本，降低了产品的价格。此外，运用本发明制造的产品体积小巧，携带方便，操作便捷，价格低廉。
此外，本发明在将封膜带完全切断的技术方案中，当撕开相邻的两个检测装置时，由于相邻的两个封膜带是完全断开的，因此撕扯力不能被传递到相邻检测装置的封膜带上，从而不会使相邻检测装置的封膜带与底卡带分离，因而不会影响到相邻检测装置的封装。
进一步的，本发明在形成未完全断开的切割线的区域利用同一把锯齿形的刀片在同一位置和一个切割步骤中既将封膜带完全切断，又不将底卡带完全切断，因而大大提高了生产效率。
附图说明
图1是现有的检测试剂盒的立体分解图；
图2是图1组合后的立体示意图；
图3是本发明多联排检测装置的制造方法之步骤B的示意图；
图4是图3所示的圆柱形第一滚刀在圆圈A内部分的局部放大示意图；
图5是本发明多联排检测装置的制造方法之步骤D的示意图；
图6是本发明多联排检测装置的制造方法之步骤E的示意图；
图7是图6之圆圈B内部分的局部放大示意图；
图8是图6所用的圆柱形第二滚刀上的第一矩形切刀的放大俯视示意图；
图9是图8沿A-A线的剖视示意图；
图10是图6所用的圆柱形第二滚刀上的第二矩形切刀的放大俯视示意图；
图11是图10沿B-B线的剖视示意图；
图12是运用本发明之制造方法生产的多联排检测装置的俯视图(虚线表示被遮挡的部分)；
图13是图12沿C-C线的剖视示意图；
图14是图13之圆圈C内部分的局部放大示意图；
图15是从图12之多联排检测装置上撕下来的单个检测装置的俯视图。
图16是采用本发明之制造方法生产的多个多联排检测装置并列排列的示意图。
图17是图16之圆圈D内部分的局部放大示意图。
图18是第二滚刀上的第一矩形切刀和第二矩形切刀平面展开后的视图。
图19是图18中圆圈“E”内部分的放大视图。
图20是图19的变更实施例。
具体实施方式
下面通过实施例，并结合附图，对本发明的技术方案作进一步具体的说明。
请参阅图3-图17所示，本发明一种多联排检测装置的制造方法，包括如下步骤：A、提供底卡带603、测试条带604和封膜带608，其中底卡带603的厚度大于封膜带608的厚度；B、如图3所示，采用圆柱形的第一滚刀605与圆柱形的垫轮605’配合，将测试条带604切割成若干个并排排列的测试条606，其中该第一滚刀605在其圆柱形外表面设置若干把片状结构的直线刀片607，直线刀片607的刀刃与圆柱形外表面的轴线平行并且与圆柱形外表面的轴线之间的距离相等，该若干把直线刀片607等间距地排列在第一滚刀605的圆柱形外表面上，使相邻两个直线刀片607的刀刃之间的距离相等，即使图4中的d1＝d2(箭头“D”表示测试条带604的传输方向，全文同)；C、如图5所示，依次将切割后的测试条606放置到底卡带603上，例如采取机械臂抓取、负压吸盘吸附测试条上表面的薄膜、人工放置测试条等方式，使相邻两个测试条606彼此等间距地间隔预先设置的距离并且粘附在底卡带上预先设置的位置；D、如图5所示，将封膜带608传输到放置有测试条606的底卡带603的上方，采用热封工艺通过热封模具621的加热和挤压(如图5箭头所示上、下运动)将封膜带608粘接到底卡带603上，并且将所述若干个测试条606分别封装在封膜带608和底卡带603之间对应的密闭空腔609内，在测试条的周围形成闭合的粘接带610；E、如图6和图7所示，采用圆柱形的第二滚刀611在粘接带610处同时切割封膜带608和底卡带603，形成未完全断开的切割线612和完全断开的切割线613，未完全断开的切割线612连接相邻的两个检测装置614，完全断开的切割线613使相邻的两个检测装置614分离，每相邻两根完全断开的切割线613之间为相同数量的若干根未完全断开的切割线612，从而形成多联排检测装置501(如图12、图13、图16和图17所示)。
如图6所示，该第二滚刀611在其圆柱形外表面等间距地设置若干把矩形切刀，这些矩形切刀包括第一矩形切刀615和第二矩形切刀615’，并且每相邻两个第二矩形切刀615’之间设置相同数量的若干个第一矩形切刀615。第一矩形切刀615和第二矩形切刀615’的长边均与圆柱形外表面的轴线平行并且长边的刀刃到圆柱形外表面轴线的距离相等。通过第二矩形切刀615’形成完全断开的切割线613，两个完全断开的切割线613之间的多个检测装置614形成多联排检测装置501。通过第一矩形切刀615形成未完全断开的切割线612，使多联排检测装置501中的单个检测装置614之间易于分离。在相邻的两个第二矩形切刀615’之间具有N个第一矩形切刀615，则形成 一个具有N+1个单个检测装置614的多联排检测装置501。比如图6中，在相邻两个第二矩形切刀615’之间有四个第一矩形切刀615，最后形成的多联排检测装置具有五个单个检测装置。与之对应，如图16所示，每相邻两个完全断开的切割线613(图16中的实线表示)之间为四根未完全断开的切割线612(图16中的虚线表示)。
图18是第二滚刀上的第一矩形切刀和第二矩形切刀平面展开后的视图，显示了第一矩形切刀和第二矩形切刀的排列方式。在一个实施例中，相邻的两个矩形切刀(包括第一矩形切刀615和第二矩形切刀615’)之间可以共用一个长边617或者617’(如图19所示)。在另一个实施例中，相邻的两个矩形切刀(包括第一矩形切刀615和第二矩形切刀615’)之间完全独立，不共用一个长边，而是各自具有二个长边617或者617’，并且相邻的两个长边之间留和适当的间隙(如图20所示)。
请参阅图4所示，在第一滚刀605之相邻两把直线刀片607之间区域放置有弹性材料618，直线刀片607的刀尖超出弹性材料618适当距离。该适当距离小于测试条606的厚度，保证测试条在被切割时压缩到弹性材料。该弹性材料618优选橡胶、泡沫、高密度海绵、硅胶、乳胶等。在相邻两把直线刀片607之间区域放置弹性材料618的优点是:当直线刀片607在切割测试条带604时，弹性材料618被切割后的测试条606压缩，因此切口更深；而当直线刀片607离开被切割后的测试条606后，弹性材料618回复原位从而将测试条606顶出来，解决了测试条606被卡在相邻两个直线刀片607之间，不容易脱离出来的技术问题。
请参阅图8和图9所示，设置在第二滚刀611之圆柱形外表面上的第一矩形切刀615的两长边616为锯齿形刀片617，该锯齿形刀片形成未完全断开的切割线612(如图7所示)，也即该未完全断开的切割线612包括下列两种技术方案：a、将封膜带608完全切断和将底卡带603部分切割(易于将单个检测装置分离)；b、将封膜带608完全切断和底卡带603未被切割(用于仅分离单个检测装置的封膜带进行检测)。锯齿形刀片617的齿部619穿透相邻两个粘接带610之间区域的封膜带608和底卡带603，从而断开相邻两个粘接带610在该区域之间的连接。其优点是减小了撕裂未完全断开的切割线612的阻力。锯齿形刀片617通过凹部620底部的刀刃仅将两个粘接带610处的封膜带完全切断形成完全断开的切口508(如图14所示)而不切割底卡带，或者在完全切断封膜带以后进一步切除位于该封膜带下面的部分底卡带(包括连续或者间 隔切割底卡带的上部分的部分深度但不贯穿至底卡带的底面，形成如图7所示的未完全断开的切割线612，和间隔切割底卡带并且使切割部分贯穿至底卡带603的底面，形成如图14所示的间隔切割线507)，形成将相邻两个检测装置614连接的未完全断开的切割线612，从而形成由若干个检测装置614组成的多联排检测装置501。优选地，选用如图20所示的第二滚刀，设置在第二滚刀611之圆柱形外表面上的锯齿形刀片617将封膜带608完全切断，在封膜带608上形成完全断开的切口508，使被切断的封膜带之间形成肉眼可见或者可被仪器检测到的间隙(该间隙有利于肉眼或者用仪器检查封膜带是否被完全切断，有助于提高产品的合格率)，但不将底卡带603完全切断(如图14所示)。即，间隔地切割底卡带603，在底卡带上切割到的区域形成贯穿切口507，在底卡带上未被切割到的区域形成连接部。进一步说，如图17所示，设置在第二滚刀611之圆柱形外表面上的锯齿形刀片617的齿部619在底卡带603上形成贯穿底卡带603的贯穿切口625，而其凹部620则不切割底卡带603，形成与贯穿切口625间隔设置的连接部626。
请参阅图10和图11所示，设置在第二滚刀611之圆柱形外表面上的第二矩形切刀615’的一个长边为锯齿形刀片617，而另一个长边为直线刀片617’(即其刀刃为没有锯齿的直线)，锯齿形刀片617如前所述，直线刀片617’将封膜带608和底卡带603均完全切断，形成完全断开的切割线613(如图17所示)，即多联排检测装置501的边，从而使多联排检测装置501与底卡带603分离，成为运用本发明的制造方法所生产的产品。
图12和图13所示即为运用本发明之制造方法生产的多联排检测装置501。该多联排检测装置501包括十个并排排列、相邻两个由非完全断开的切割线612连接的检测装置614。每一个检测装置614形成有环形跑道形状的粘接带610。图14显示了相邻两个检测装置614在连接处的结构。
图15显示了从多联排检测装置501上撕下来的单个检测装置614的结构，其中虚线表示被遮挡的部分。
图16显示了一个多联排检测装置包括五个单个检测装置时的平面排列方式，尤其显示了未完全断开的切割线612与完全断开的切割线613的平面排列方式，即，在相邻的两个完全断开的切割线613(图中实线所示)之间具有四个未完全断开的切割线 612(图中虚线所示)。
底卡带603优选采用防潮和防氧化的PE或者PP材料，其厚度优选介于0.2毫米至1.5毫米之间。封膜带608优选采用防潮和防氧化的PE或者PP或者PET材料，其厚度优选厚度介于0.02毫米至0.1毫米之间。由于底卡带603的厚度远远大于封膜带608的厚度，因此，底卡带603具有适度的刚性和较高的强度，而封膜带608则较柔软，具有较好的抗拉伸和抗撕裂性能，两者均适合于运用本发明的制造方法在自动化设备上生产出价格低廉的产品。
虽然图12和图13显示了一个多联排检测装置501包括了十个并排排列的检测装置614，但是数量十个是可变的，也可以是二个、五个、二十个等任何合适的数量，即运用本发明之制造方法生产的多联排检测装置可以根据实际需要设定其所包括的检测装置614的个数。
本发明在将封膜带完全切断的技术方案中，当撕开相邻的两个检测装置614时，由于相邻的两个封膜带608是完全断开的，因此撕扯力不能被传递到相邻检测装置的封膜带608上，从而不会使相邻检测装置的封膜带608与底卡带603分离，因而不会影响到相邻检测装置614的封装。
进一步的，本发明在形成未完全断开的切割线的区域利用同一把锯齿形的刀片在同一位置和一个切割步骤中既将封膜带608完全切断，又不将底卡带603完全切断，因而大大提高了生产效率。
以上的描述仅为本发明的具体实施方式，并非因此限制本发明所要求保护的范围。凡是利用本发明说明书及附图内容所作的等效结构或等效流程变换，或直接或间接运用在其它相关的技术领域，均应当包括在本发明的保护范围内。

Claims (9)

  1. 一种多联排检测装置的制造方法，其特征在于包括如下步骤：
    A、提供底卡带、测试条带和封膜带，其中底卡带的厚度大于封膜带的厚度；
    B、采用圆柱形的第一滚刀将测试条带切割成若干个并排排列的测试条，其中该第一滚刀在其圆柱形外表面设置若干把直线切刀，直线切刀与圆柱形外表面的轴线平行并且与圆柱形外表面的轴线之间的距离相等，该若干把直线切刀等间距地排列在第一滚刀的圆柱形外表面上；
    C、依次将切割后的测试条放置到底卡带上，使测试条粘附在底卡带上预先设置的位置上；
    D、将封膜带传输到底卡带的上方，采用热封工艺通过加热和挤压将封膜带粘接到底卡带上，并且将所述若干个测试条分别封装在封膜带和底卡带之间对应的密闭空腔内，在测试条的周围形成闭合的粘接带；
    E、采用圆柱形的第二滚刀切割封膜带和底卡带，形成未完全断开的切割线和完全断开的切割线，未完全断开的切割线使相邻的两个检测装置相连接，完全断开的切割线使相邻的两个检测装置相分离，每相邻两根完全断开的切割线之间为相同数量的若干根未完全断开的切割线从而形成多联排检测装置。
  2. 如权利要求1所述的多联排检测装置的制造方法，其特征在于：在第一滚刀之相邻两把直线切刀之间区域放置有弹性材料，直线切刀的刀尖超出弹性材料适当距离。
  3. 如权利要求1所述的多联排检测装置的制造方法，其特征在于：第二滚刀在其圆柱形外表面等间距地设置若干把第一矩形切刀和第二矩形切刀，每相邻两个第二矩形切刀之间有数量相等的若干个第一矩形切刀；第一矩形切刀和第二矩形切刀的长边与圆柱形外表面的轴线平行；第一矩形切刀形成两根未完全断开的切割线，第二矩形切刀形成一根未完全断开的切割线和一根完全断开的切割线。
  4. 如权利要求3所述的多联排检测装置的制造方法，其特征在于：设置在第二滚刀之圆柱形外表面上的第一矩形切刀的两个长边为锯齿形刀片，该锯齿形刀片形成未完全断开的切割线。
  5. 如权利要求4所述的多联排检测装置的制造方法，其特征在于：设置在第二滚 刀之圆柱形外表面上的锯齿形刀片将封膜带完全切断，但不将底卡带完全切断或者不切割底卡带。
  6. 如权利要求3所述的多联排检测装置的制造方法，其特征在于：设置在第二滚刀之圆柱形外表面上的第二矩形切刀的一个长边为直线刀片，另一个长边为锯齿形刀片，该直线刀片形成完全断开的切割线，锯齿形刀片形成未完全断开的切割线。
  7. 如权利要求6所述的多联排检测装置的制造方法，其特征在于：第二矩形切刀的直线刀片将封膜带和底卡带均完全切断，第二矩形切刀的锯齿形刀片将封膜带完全切断，但不将底卡带完全切断或者不切割底卡带。
  8. 如权利要求1所述的多联排检测装置的制造方法，其特征在于：底卡带的厚度介于0.2毫米至1.5毫米之间，封膜带的厚度介于0.02毫米至0.1毫米之间。
  9. 如权利要求7所述的多联排检测装置的制造方法，其特征在于：底卡带的厚度介于0.2毫米至1.5毫米之间，封膜带的厚度介于0.02毫米至0.1毫米之间。
PCT/CN2022/132929 2022-04-08 2022-11-18 一种多联排检测装置的制造方法 WO2023193445A1 (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US18/850,061 US20250214077A1 (en) 2022-04-08 2022-11-18 Manufacturing method of multi-lined detection device
EP22871049.7A EP4286120A4 (en) 2022-04-08 2022-11-18 METHOD OF MANUFACTURING MULTI-ROW DETECTION DEVICE

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN202210370196.8 2022-04-08
CN202210370196 2022-04-08
CN202210442651.0A CN114536470B (zh) 2022-04-08 2022-04-26 一种多联排检测装置的制造方法
CN202210442651.0 2022-04-26

Publications (1)

Publication Number Publication Date
WO2023193445A1 true WO2023193445A1 (zh) 2023-10-12

Family

ID=81667155

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/CN2022/132929 WO2023193445A1 (zh) 2022-04-08 2022-11-18 一种多联排检测装置的制造方法
PCT/CN2022/132931 WO2023193446A1 (zh) 2022-04-08 2022-11-18 一种多联排检测装置

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/CN2022/132931 WO2023193446A1 (zh) 2022-04-08 2022-11-18 一种多联排检测装置

Country Status (5)

Country Link
US (1) US20250214077A1 (zh)
EP (2) EP4279414B1 (zh)
CN (5) CN218099199U (zh)
ES (1) ES3022259T3 (zh)
WO (2) WO2023193445A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN218099199U (zh) * 2022-04-08 2022-12-20 艾康生物技术(杭州)有限公司 一种检测装置

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2329621Y (zh) * 1998-06-29 1999-07-21 姚崇德 试纸密封包装片
JP2008239194A (ja) * 2007-03-27 2008-10-09 Dainippon Printing Co Ltd 密封袋の製造方法及び装置
CN103057765A (zh) * 2013-01-25 2013-04-24 宁夏松久自动化设备有限公司 包装膜切膜装置
CN204789585U (zh) * 2015-07-23 2015-11-18 深圳市检验检疫科学研究院 用于检测牛原乳的免疫层析试纸
US20180209971A1 (en) * 2015-07-28 2018-07-26 ApolloDX, LLC Test strip for diagnostic testing
CN112027193A (zh) * 2020-09-21 2020-12-04 苏州怡拓生物传感技术有限公司 一种多联排试条自动装袋生产设备
CN213081605U (zh) * 2020-09-21 2021-04-30 苏州怡拓生物传感技术有限公司 一种试条滚切分料机构
CN114536470A (zh) * 2022-04-08 2022-05-27 艾康生物技术(杭州)有限公司 一种多联排检测装置的制造方法

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2700556A (en) * 1951-08-17 1955-01-25 Ibm Continuous form with separable portions
JP3020311B2 (ja) * 1991-07-03 2000-03-15 広栄化学工業株式会社 発熱体製造用切断装置
DE4439224A1 (de) * 1994-11-03 1996-05-09 Bosch Gmbh Robert Vorrichtung zum Bearbeiten eines Näpfe aufweisenden Folienstranges
JPH10152167A (ja) * 1996-11-19 1998-06-09 Dainippon Printing Co Ltd 包装体
US5794774A (en) * 1997-05-12 1998-08-18 Porcelli; V. Lorenzo Disposable oral hygiene applicator
DE29717187U1 (de) * 1997-09-25 1999-01-28 THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte, 82229 Seefeld Wiederverschließbare Verpackung
US6033627A (en) * 1997-11-17 2000-03-07 Smithkline Diagnostics, Inc. Bevel closure assay device housing
WO2000034145A1 (de) * 1998-12-09 2000-06-15 Lts Lohmann Therapie-Systeme Ag Verpackung für flächenförmige gebilde/produkte
CN2366849Y (zh) * 1999-04-22 2000-03-01 罗福海 体外诊断检测卡
JP2004114582A (ja) * 2002-09-27 2004-04-15 Mitsubishi Plastics Ind Ltd 熱成形用ポリエステルシート及び包装体
CA2421989A1 (en) * 2003-03-13 2004-09-13 Henrikus Vink Cigarette package
NL1023550C2 (nl) * 2003-05-27 2004-11-30 Beek Bv A A Ter Verpakking voor baksels en gebruik daarvan.
EP1639352B8 (en) * 2003-06-20 2018-07-11 Roche Diabetes Care GmbH Method and reagent for producing narrow, homogenous reagent strips
DE102004047445B4 (de) * 2004-09-30 2007-05-31 Lts Lohmann Therapie-Systeme Ag Nichtwiederverschließbare Verpackung für gesundheitsgefährdende Erzeugnisse, Verwendung der Verpackung, sowie Verfahren zu deren Herstellung
FR2876986B1 (fr) * 2004-10-25 2006-12-29 Cryolog Sa Sa Procede pour conditionner de maniere hermetique et a haute cadence, un gel actif riche en eau et/ou contenant des micro-organismes
JP2006182364A (ja) * 2004-12-27 2006-07-13 Aji Nihon Kk 包装体連結帯加工具、包装体連結帯加工装置、包装体製造システム及び包装体製造方法
GB0502252D0 (en) * 2005-02-03 2005-03-09 Meridica Ltd Container for medical products and method of sealing thereof
DE102005033875A1 (de) * 2005-07-20 2007-02-01 Mapa Gmbh Gummi- Und Plastikwerke Verpackung für Kondome
DE102005035705A1 (de) * 2005-07-27 2007-02-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Arzneimittelblister
JP2007178376A (ja) * 2005-12-28 2007-07-12 Sysmex Corp 試験片収容体、その製造方法
EP1967465A1 (en) * 2007-03-05 2008-09-10 Mars Incorporated Packaged products and array or bandoleer of packaged products
CN201058704Y (zh) * 2007-07-25 2008-05-14 修正药业集团股份有限公司 一种药品铝塑包装板
CN201076603Y (zh) * 2007-09-28 2008-06-25 宁波立华制药有限公司 一种药品包装板
US20100051455A1 (en) * 2008-08-26 2010-03-04 Roche Diagnostics Operations, Inc. Biosensor test strip cards
ES2546503T3 (es) * 2008-09-08 2015-09-24 Lts Lohmann Therapie-Systeme Ag Envase de dosis individual seguro para niños para sistemas terapéuticos transdérmicos o formas de administración en forma de lámina
DE102009025471A1 (de) * 2009-06-12 2010-12-16 Varta Microbattery Gmbh Verkaufs- und Vorratspackung für Zink/Luft-Knopfzellen
CN202594092U (zh) * 2012-03-08 2012-12-12 宁波日鼎电子科技有限公司 一种连接器包装结构
JP5997924B2 (ja) * 2012-04-18 2016-09-28 富士製薬工業株式会社 易開封ブリスター包装体
JP2014118193A (ja) * 2012-12-18 2014-06-30 Sekisui Giken:Kk 容器連接体
JP2014176597A (ja) * 2013-07-04 2014-09-25 Kanae Co Ltd ラベル
CN203688538U (zh) * 2014-01-16 2014-07-02 北京亦庄国际诊断试剂技术有限公司 一种封装试纸条及试纸条长带
KR20160072721A (ko) * 2014-12-15 2016-06-23 (주)크레템 약제포장장치
CN205854944U (zh) * 2016-07-04 2017-01-04 万华普曼生物工程有限公司 一种检测试纸类泡罩式包装结构
CN207060848U (zh) * 2017-03-01 2018-03-02 秦皇岛博硕光电设备股份有限公司 固体药剂内包装容器用的密封板
CN108051596A (zh) * 2018-01-18 2018-05-18 凌中鑫 一种无创血糖测试试纸及其制备方法
CN208516076U (zh) * 2018-05-17 2019-02-19 澳诺（中国）制药有限公司 一种口服液塑料包装瓶
CN108688854A (zh) * 2018-05-23 2018-10-23 东莞理工学院 一种用于刀片的双面封膜包装机
CN209192696U (zh) * 2018-10-24 2019-08-02 福建凯龙医疗卫生材料有限公司 易揭吸湿包装袋
CN211732447U (zh) * 2020-03-18 2020-10-23 郑州韩都药业集团有限公司 一种新型胶囊药铝塑包装板
CN211845668U (zh) * 2020-03-30 2020-11-03 南京信息工程大学 一种酱料盒
CN212474409U (zh) * 2020-05-08 2021-02-05 湖南可孚医疗设备有限公司 试纸储存筒

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2329621Y (zh) * 1998-06-29 1999-07-21 姚崇德 试纸密封包装片
JP2008239194A (ja) * 2007-03-27 2008-10-09 Dainippon Printing Co Ltd 密封袋の製造方法及び装置
CN103057765A (zh) * 2013-01-25 2013-04-24 宁夏松久自动化设备有限公司 包装膜切膜装置
CN204789585U (zh) * 2015-07-23 2015-11-18 深圳市检验检疫科学研究院 用于检测牛原乳的免疫层析试纸
US20180209971A1 (en) * 2015-07-28 2018-07-26 ApolloDX, LLC Test strip for diagnostic testing
CN112027193A (zh) * 2020-09-21 2020-12-04 苏州怡拓生物传感技术有限公司 一种多联排试条自动装袋生产设备
CN213081605U (zh) * 2020-09-21 2021-04-30 苏州怡拓生物传感技术有限公司 一种试条滚切分料机构
CN114536470A (zh) * 2022-04-08 2022-05-27 艾康生物技术(杭州)有限公司 一种多联排检测装置的制造方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP4286120A4 *

Also Published As

Publication number Publication date
WO2023193446A1 (zh) 2023-10-12
CN114563557B (zh) 2022-09-13
CN217688977U (zh) 2022-10-28
EP4279414B1 (en) 2025-01-22
CN114536470A (zh) 2022-05-27
EP4286120A4 (en) 2024-08-28
EP4279414A1 (en) 2023-11-22
US20250214077A1 (en) 2025-07-03
ES3022259T3 (en) 2025-05-28
CN218099199U (zh) 2022-12-20
CN114536470B (zh) 2022-08-12
CN218766938U (zh) 2023-03-28
EP4286120A1 (en) 2023-12-06
CN114563557A (zh) 2022-05-31

Similar Documents

Publication Publication Date Title
JP6970232B2 (ja) 多層フィルム及び再封可能なフィルムパッケージ
WO2023193445A1 (zh) 一种多联排检测装置的制造方法
US4136776A (en) Disposable thermometer sheath package
CN106590455A (zh) 绝缘Mylar的制备工艺
JP2018149036A (ja) 医療用容器
EA034295B1 (ru) Блистерная полоска
CN204287185U (zh) 一种检测试剂盒
JP5720432B2 (ja) 被検体分析用チップおよびその製造方法
CN109398915B (zh) 用于洁净环境降低微粒的灭菌袋及其制备工艺
CN101721217A (zh) 采血器具
CN212610407U (zh) 一种便于撕下隔离纸的胶带
CN219050149U (zh) 一种放射治疗模拟定位专用铅丝胶带
CN216629197U (zh) 三伏贴
CN219375218U (zh) 急救包的十二个格内袋
CN203502247U (zh) 医用灭菌纸塑包装袋封口测试纸
CN209847580U (zh) 设置剥离口的创口贴
TWM582026U (zh) Easy stamping film structure of beverage container
JP2005162303A (ja) 包装材およびその製造方法
CN209751061U (zh) 一种血站护理用一次性采血护理包
CN218989164U (zh) 一种防离型膜开胶的撕拉结构
CN215049844U (zh) 一种药用ptp铝箔
CN210338925U (zh) 一种塑料薄膜
CN214410521U (zh) 一种不干胶标签
CN210204939U (zh) 一种皮肤点刺定位板
JP2019182460A (ja) 易開封性包装袋

Legal Events

Date Code Title Description
ENP Entry into the national phase

Ref document number: 2022871049

Country of ref document: EP

Effective date: 20230328

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 22871049

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 18850061

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

WWP Wipo information: published in national office

Ref document number: 18850061

Country of ref document: US