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WO2013104916A3 - Medical devices, coatings and compounds - Google Patents

Medical devices, coatings and compounds Download PDF

Info

Publication number
WO2013104916A3
WO2013104916A3 PCT/GB2013/050052 GB2013050052W WO2013104916A3 WO 2013104916 A3 WO2013104916 A3 WO 2013104916A3 GB 2013050052 W GB2013050052 W GB 2013050052W WO 2013104916 A3 WO2013104916 A3 WO 2013104916A3
Authority
WO
WIPO (PCT)
Prior art keywords
medical devices
compounds
coatings
calixarene
implantable medical
Prior art date
Application number
PCT/GB2013/050052
Other languages
French (fr)
Other versions
WO2013104916A2 (en
Inventor
Iain John BARLOW
Nicholas Hendrik WILLIAMS
Charles James Matthew Stirling
Original Assignee
Camstent Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Camstent Limited filed Critical Camstent Limited
Publication of WO2013104916A2 publication Critical patent/WO2013104916A2/en
Publication of WO2013104916A3 publication Critical patent/WO2013104916A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/14—Post-treatment to improve physical properties
    • A61L17/145—Coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Paints Or Removers (AREA)

Abstract

Implantable medical devices, such as catheters, which comprise a calixarene-derived coating that resists adhesion and/or colonisation of bacteria and/or fungi are described. Also described are calixarene-derived coating materials, intermediates useful in their manufacture, processes for their preparation, and methods for coating of implantable medical devices with the calixarene compounds.
PCT/GB2013/050052 2012-01-11 2013-01-11 Medical devices, coatings and compounds WO2013104916A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1200388.5 2012-01-11
GB1200388.5A GB2498356B (en) 2012-01-11 2012-01-11 Calixarene-derived coatings for implantable medical devices

Publications (2)

Publication Number Publication Date
WO2013104916A2 WO2013104916A2 (en) 2013-07-18
WO2013104916A3 true WO2013104916A3 (en) 2013-10-17

Family

ID=45788744

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2013/050052 WO2013104916A2 (en) 2012-01-11 2013-01-11 Medical devices, coatings and compounds

Country Status (2)

Country Link
GB (1) GB2498356B (en)
WO (1) WO2013104916A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014236587A1 (en) * 2013-03-14 2015-07-16 Teleflex Medical Incorporated Local drug delivery
EP3334706B1 (en) * 2015-08-10 2020-09-30 Ramot at Tel-Aviv University Ltd. Pillararenes and uses thereof
US20220288282A1 (en) * 2021-03-15 2022-09-15 Convatec Limited Intermittent catheters
GB202103549D0 (en) 2021-03-15 2021-04-28 Convatec Ltd Intermittent catheters

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002083176A2 (en) * 2001-04-17 2002-10-24 University Of Sheffield Biomaterials comprising a melanocyte stimulating hormone (msh), and method of forming
GB2448153A (en) * 2007-04-04 2008-10-08 Camstent Ltd Mbe Coated Implantable Medical Devices
US20110130465A1 (en) * 2009-12-01 2011-06-02 Nerites Corporation Coatings for prevention of biofilms

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4445998A (en) 1981-12-02 1984-05-01 Toyo Kohan Co., Ltd. Method for producing a steel lithographic plate
US5053048A (en) 1988-09-22 1991-10-01 Cordis Corporation Thromboresistant coating
DE19533310A1 (en) 1995-07-24 1997-01-30 Iro Ab Thread delivery device
GB2312178A (en) 1996-04-16 1997-10-22 Univ Sheffield New calixarenes and their use in waterproofing
US6602287B1 (en) 1999-12-08 2003-08-05 Advanced Cardiovascular Systems, Inc. Stent with anti-thrombogenic coating
US7276286B2 (en) 2000-07-17 2007-10-02 President & Fellows Of Harvard College Surfaces that resist the adsorption of biological species
US7070798B1 (en) 2002-06-21 2006-07-04 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine
GB2392163A (en) 2002-08-20 2004-02-25 Univ Sheffield Soluble phenol-aldehyde condensate
US6702850B1 (en) 2002-09-30 2004-03-09 Mediplex Corporation Korea Multi-coated drug-eluting stent for antithrombosis and antirestenosis
US20050221072A1 (en) 2003-04-17 2005-10-06 Nanosys, Inc. Medical device applications of nanostructured surfaces
WO2005112570A2 (en) 2004-05-12 2005-12-01 Medtronic Vascular, Inc. Drug-polymer coated stent
CN102355789B (en) 2004-11-05 2014-06-11 陶氏康宁爱尔兰有限公司 A process for plasma treating a surface

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002083176A2 (en) * 2001-04-17 2002-10-24 University Of Sheffield Biomaterials comprising a melanocyte stimulating hormone (msh), and method of forming
GB2448153A (en) * 2007-04-04 2008-10-08 Camstent Ltd Mbe Coated Implantable Medical Devices
US20110130465A1 (en) * 2009-12-01 2011-06-02 Nerites Corporation Coatings for prevention of biofilms

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AGUSTÍ LLEDÓ ET AL: "Deep cavitand receptors with pH-independent water solubility", CHEMICAL COMMUNICATIONS, vol. 46, no. 45, 1 January 2010 (2010-01-01), pages 8630, XP055074252, ISSN: 1359-7345, DOI: 10.1039/c0cc03388j *
GRAZIA M L CONSOLI ET AL: "Multivalent calixarene-based-fucosyl derivative: a newbiofilm inhibitor", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 52, no. 44, 24 August 2011 (2011-08-24), pages 5831 - 5834, XP028301577, ISSN: 0040-4039, [retrieved on 20110831], DOI: 10.1016/J.TETLET.2011.08.142 *
KARIN WÖLLNER ET AL: "Interaction behaviour of a PDMS-calixarene system and polar analytes characterised by microcalorimetry and spectroscopic methods", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, SPRINGER, BERLIN, DE, vol. 389, no. 6, 5 October 2007 (2007-10-05), pages 1879 - 1887, XP019559858, ISSN: 1618-2650, DOI: 10.1007/S00216-007-1600-9 *
SHOICHI SAITO ET AL: "Lower Rim Functionalized Resorcinarenes: Useful Modules for Supramolecular Chemistry", ORGANIC LETTERS, vol. 1, no. 8, 1 October 1999 (1999-10-01), pages 1241 - 1244, XP055074247, ISSN: 1523-7060, DOI: 10.1021/ol9902125 *

Also Published As

Publication number Publication date
GB201200388D0 (en) 2012-02-22
WO2013104916A2 (en) 2013-07-18
GB2498356B (en) 2016-09-07
GB2498356A (en) 2013-07-17

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