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WO2013099789A1 - Procédé de stérilisation et dispositif de stérilisation - Google Patents

Procédé de stérilisation et dispositif de stérilisation Download PDF

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Publication number
WO2013099789A1
WO2013099789A1 PCT/JP2012/083210 JP2012083210W WO2013099789A1 WO 2013099789 A1 WO2013099789 A1 WO 2013099789A1 JP 2012083210 W JP2012083210 W JP 2012083210W WO 2013099789 A1 WO2013099789 A1 WO 2013099789A1
Authority
WO
WIPO (PCT)
Prior art keywords
hydrogen peroxide
sterilization
solvent
liquid
sterilizing
Prior art date
Application number
PCT/JP2012/083210
Other languages
English (en)
Japanese (ja)
Inventor
睦 早川
唯子 中村
Original Assignee
大日本印刷株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 大日本印刷株式会社 filed Critical 大日本印刷株式会社
Priority to JP2013551673A priority Critical patent/JP6191462B2/ja
Publication of WO2013099789A1 publication Critical patent/WO2013099789A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/22—Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A61L2/186—Peroxide solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/23—Containers, e.g. vials, bottles, syringes, mail
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
    • B65B55/10—Sterilising wrappers or receptacles prior to, or during, packaging by liquids or gases

Definitions

  • the present invention relates to a hydrogen peroxide sterilizing solution. More specifically, when aseptically filling fruit juice beverages, coffee beverages, other soft drinks, etc. into polyethylene terephthalate bottles (hereinafter referred to as PET bottles) or paper containers, PET bottles, PET bottle preforms, or paper containers
  • PET bottles polyethylene terephthalate bottles
  • the present invention relates to a hydrogen peroxide sterilizing liquid used for sterilizing containers such as, a sterilizing method and a sterilizing apparatus using the same.
  • the invention according to claim 1 uses a hydrogen peroxide sterilizing solution obtained by dissolving hydrogen peroxide in a solvent having a boiling point of less than 100 ° C.
  • a sterilization method including a step of adhering to an object and a step of drying the object to be sterilized with hot air is employed.
  • the solvent may be a mixed solution of water and an alcohol having a boiling point of less than 100 ° C.
  • the alcohol may be ethyl alcohol, and the mixing volume ratio of water and ethyl alcohol may be 1: 199 to 1: 0.5.
  • the boiling point of the solvent for dissolving hydrogen peroxide is less than 100 ° C., that is, the boiling point is lower than that of water, Compared to the solvent, it is easy to vaporize. Therefore, when the hydrogen peroxide sterilization liquid of the present invention is heated and used as a condensation mist, the vaporization of the solvent proceeds at a low temperature and in a short time compared to the conventional hydrogen peroxide sterilization liquid, and the hydrogen peroxide sterilization liquid correspondingly. It is possible to quickly increase the concentration of hydrogen peroxide therein, thereby obtaining a higher sterilization effect and sterilization efficiency than conventional ones. In other words, while setting the hydrogen peroxide concentration in the hydrogen peroxide sterilizing solution to be low, the concentration can be increased during use.
  • the hydrogen peroxide concentration in the hydrogen peroxide sterilizing solution can be designed to be low, and the alcohol as a hydrophobic component is added to the sterilizing agent, so that the hydrogen peroxide is added to the resin. It can also be prevented from adsorbing and penetrating and remaining in a container which is an object of sterilization.
  • the sterilization method and sterilization apparatus of the present invention since it has a step (means) for drying with hot air, the hydrogen peroxide concentration can be quickly increased, and the above-mentioned effects can be exhibited smoothly. can do.
  • the hydrogen peroxide sterilization liquid used in the present embodiment is composed of hydrogen peroxide (A) and a solvent (B) for dissolving the hydrogen peroxide (A), and the solvent (B) is a liquid having a boiling point of less than 100 ° C. It has characteristics. Each will be described below.
  • (A) Hydrogen peroxide As the hydrogen peroxide used in this embodiment, a commercially available aqueous hydrogen peroxide solution having a hydrogen peroxide concentration of 30 to 35% by weight can be usually mentioned. A 3% by weight aqueous hydrogen peroxide solution marketed as oxidol can also be used. There are 30 to 35% by weight aqueous hydrogen peroxide solution for industrial use and food additives, and both can be used in this embodiment, but industrial use is stable to prevent decomposition of hydrogen peroxide. Since an agent or the like is added, an aqueous hydrogen peroxide solution for food additives with few additives is preferable.
  • the solvent used in this embodiment is not particularly limited as long as it has a boiling point of less than 100 ° C. and can dissolve the hydrogen peroxide.
  • a solvent having a boiling point of less than 100 ° C. the solvent can be vaporized more smoothly than a conventional hydrogen peroxide sterilizing solution using water (boiling point is 100 ° C.) as a solvent.
  • the concentration of hydrogen peroxide can be improved over time (the concentration of hydrogen peroxide increases as the solvent is evaporated). As a result, the sterilization effect and sterilization efficiency can be improved.
  • Such a solvent may be a single substance or a mixture.
  • methyl alcohol, ethyl alcohol, isopropyl alcohol, acetone and the like can be suitably used, and among these, ethyl alcohol is particularly preferable. Since ethyl alcohol is recognized as a food additive, it can be used as a sterilization target for food containers, and is easy to obtain and handle and relatively inexpensive.
  • the solvent when the solvent is a mixture, it is preferable to use a mixture of the above methyl alcohol, ethyl alcohol, isopropyl alcohol, acetone and the like and water. It is particularly preferred to use a mixture of alcohol and water.
  • the mixing volume ratio can be appropriately selected in consideration of the boiling point of the whole solvent.
  • the mixing volume ratio is preferably 1: 199 to 1: 0.5. This is because, by various experiments, effective results could be obtained within this range.
  • the hydrogen peroxide sterilization liquid described above is used for sterilization of plastic containers represented by PET bottles, sterilization of preforms before molding PET bottles, and further sterilization of paper containers filled with dairy products, etc. It can be used for sterilization of various containers.
  • the method includes a step of adhering the hydrogen peroxide sterilization liquid to an object to be sterilized, and a step of drying the object to be sterilized with hot air, and sterilizing the hydrogen peroxide sterilization liquid. It can be suitably used in a sterilization apparatus including means for adhering to an object and means for drying the object to be sterilized with hot air.
  • the hydrogen peroxide sterilizing liquid is misted by the mist generator shown in FIG. Uniform adhesion is possible.
  • the mist generator includes a hydrogen peroxide sterilizing liquid supply unit 1 that is a two-fluid spray that supplies hydrogen peroxide sterilizing liquid in a drop form, and the hydrogen peroxide sterilizing liquid supply unit 1. And a vaporizing section 2 for heating and atomizing the spray of the supplied hydrogen peroxide sterilizing liquid to a non-decomposition temperature equal to or higher than its boiling point.
  • the hydrogen peroxide sterilizing liquid supply unit 1 introduces the hydrogen peroxide sterilizing liquid and compressed air from the hydrogen peroxide sterilizing liquid supply path 1a and the compressed air supply path 1b, respectively, and sprays the hydrogen peroxide sterilizing liquid into the vaporizing unit 9. It is supposed to be.
  • the vaporizer 2 is a pipe having a heater 2a sandwiched between inner and outer walls, and heats and vaporizes the spray of the hydrogen peroxide sterilizing solution blown into the pipe.
  • This vaporized mixture is a mixture of hydrogen peroxide gas and solvent gas, and is ejected as condensed mist from the discharge nozzle 2b to the outside of the vaporizing section 2.
  • this mist is introduced into the PET bottle in the process of attaching the hydrogen peroxide sterilizing solution to the object to be sterilized.
  • the step (means) for attaching the hydrogen peroxide sterilizing solution and the drying step (means) are not particularly limited, and conventionally known steps (means) can be used.
  • Example 1 A hydrogen peroxide sterilizing solution of Example 1 was produced with hydrogen peroxide: 27.1% by volume, water: 23.1% by volume, and ethanol: 49.8% by volume.
  • the solvent of this sterilizing solution is a mixture of water and ethanol, and its boiling point is less than 100 ° C.
  • the residual hydrogen peroxide concentration in the bottle was measured by the oxygen electrode method.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

L'invention concerne un procédé de stérilisation utilisant un stérilisateur liquide comprenant du peroxyde d'hydrogène, ledit stérilisateur liquide étant préparé par dissolution de peroxyde d'hydrogène dans un solvant, dans lequel un liquide ayant un point d'ébullition inférieur à 100°C est utilisé comme solvant. Par stérilisation d'un contenant en matière plastique moulé exemplifié par une bouteille de poly(téréphtalate d'éthylène) ou un contenant en papier par fixation d'un brouillard du stérilisateur liquide précité comprenant du peroxyde d'hydrogène sur celui-ci, un effet de stérilisation et un rendement de stérilisation peuvent être accrus et la quantité de stérilisateur restant dans le contenant peut être réduite.
PCT/JP2012/083210 2011-12-27 2012-12-21 Procédé de stérilisation et dispositif de stérilisation WO2013099789A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2013551673A JP6191462B2 (ja) 2011-12-27 2012-12-21 殺菌方法及び殺菌装置

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011-286820 2011-12-27
JP2011286820 2011-12-27

Publications (1)

Publication Number Publication Date
WO2013099789A1 true WO2013099789A1 (fr) 2013-07-04

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PCT/JP2012/083210 WO2013099789A1 (fr) 2011-12-27 2012-12-21 Procédé de stérilisation et dispositif de stérilisation

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JP (1) JP6191462B2 (fr)
WO (1) WO2013099789A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015171812A (ja) * 2014-02-19 2015-10-01 大日本印刷株式会社 ブロー成形機及びその殺菌方法
WO2016143772A1 (fr) * 2015-03-09 2016-09-15 大日本印刷株式会社 Machine de moulage par soufflage et son procédé de stérilisation
JP2016190500A (ja) * 2014-02-19 2016-11-10 大日本印刷株式会社 ブロー成形機及びその殺菌方法
WO2017221991A1 (fr) 2016-06-24 2017-12-28 大日本印刷株式会社 Procédé et dispositif pour stérilisation de préforme
JP2018020529A (ja) * 2016-08-05 2018-02-08 大日本印刷株式会社 プリフォームの殺菌方法及び装置
JP2018134874A (ja) * 2018-04-25 2018-08-30 大日本印刷株式会社 プリフォームの殺菌方法及び装置

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07315345A (ja) * 1994-05-27 1995-12-05 Toppan Printing Co Ltd 飲料用液体容器または飲料用液体充填装置の滅菌方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63110122A (ja) * 1986-10-15 1988-05-14 シ−ケ−デイ株式会社 容器等の滅菌方法
JP4334670B2 (ja) * 1999-05-20 2009-09-30 大日本印刷株式会社 容器の殺菌方法
JP5401828B2 (ja) * 2008-05-20 2014-01-29 大日本印刷株式会社 容器の殺菌方法及び装置
JP5784275B2 (ja) * 2009-02-06 2015-09-24 大日本印刷株式会社 飲料充填方法及び装置

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07315345A (ja) * 1994-05-27 1995-12-05 Toppan Printing Co Ltd 飲料用液体容器または飲料用液体充填装置の滅菌方法

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3109030A4 (fr) * 2014-02-19 2018-02-21 Dai Nippon Printing Co., Ltd. Machine à mouler par soufflage et procédé de stérilisation de celle-ci
CN105829065A (zh) * 2014-02-19 2016-08-03 大日本印刷株式会社 吹塑成型机及其杀菌方法
US10046506B2 (en) 2014-02-19 2018-08-14 Dai Nippon Printing Co., Ltd. Blow molding machine and method for sterilizing the same
JP2016190500A (ja) * 2014-02-19 2016-11-10 大日本印刷株式会社 ブロー成形機及びその殺菌方法
JP2015171812A (ja) * 2014-02-19 2015-10-01 大日本印刷株式会社 ブロー成形機及びその殺菌方法
CN107206663A (zh) * 2015-03-09 2017-09-26 大日本印刷株式会社 吹塑成型机及其杀菌方法
JPWO2016143772A1 (ja) * 2015-03-09 2017-12-28 大日本印刷株式会社 ブロー成形機及びその殺菌方法
WO2016143772A1 (fr) * 2015-03-09 2016-09-15 大日本印刷株式会社 Machine de moulage par soufflage et son procédé de stérilisation
EP3269529A4 (fr) * 2015-03-09 2018-10-03 Dai Nippon Printing Co., Ltd. Machine de moulage par soufflage et son procédé de stérilisation
US10543636B2 (en) 2015-03-09 2020-01-28 Dai Nippon Printing Co., Ltd. Blow-molding machine and method of sterilizing the same
CN107206663B (zh) * 2015-03-09 2020-06-12 大日本印刷株式会社 吹塑成型机及其杀菌方法
US11077602B2 (en) 2015-03-09 2021-08-03 Dai Nippon Printing Co., Ltd. Blow-molding machine and method of sterilizing the same
WO2017221991A1 (fr) 2016-06-24 2017-12-28 大日本印刷株式会社 Procédé et dispositif pour stérilisation de préforme
CN109414869A (zh) * 2016-06-24 2019-03-01 大日本印刷株式会社 预成型坯的杀菌方法及装置
US11110641B2 (en) 2016-06-24 2021-09-07 Dai Nippon Printing Co., Ltd. Method and apparatus for sterilizing preform
JP2018020529A (ja) * 2016-08-05 2018-02-08 大日本印刷株式会社 プリフォームの殺菌方法及び装置
JP2018134874A (ja) * 2018-04-25 2018-08-30 大日本印刷株式会社 プリフォームの殺菌方法及び装置

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JP6191462B2 (ja) 2017-09-06

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