WO2008105175A1 - 酵母の製造方法,酵母,及び乳酸の製造方法 - Google Patents
酵母の製造方法,酵母,及び乳酸の製造方法 Download PDFInfo
- Publication number
- WO2008105175A1 WO2008105175A1 PCT/JP2008/000353 JP2008000353W WO2008105175A1 WO 2008105175 A1 WO2008105175 A1 WO 2008105175A1 JP 2008000353 W JP2008000353 W JP 2008000353W WO 2008105175 A1 WO2008105175 A1 WO 2008105175A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- yeast
- lactic acid
- producing lactic
- ability
- synthesize
- Prior art date
Links
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 title abstract 22
- 235000014655 lactic acid Nutrition 0.000 title abstract 11
- 239000004310 lactic acid Substances 0.000 title abstract 11
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 10
- 238000000034 method Methods 0.000 title abstract 5
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/56—Lactic acid
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
【課題】乳酸合成能を有する酵母,及び酵母を用いた乳酸の製造方法を提供する。本発明は,乳酸耐性や乳酸合成能に優れた酵母を提供することを目的とする。本発明は,酵母を用いた効果的な乳酸の製造方法を提供することを目的とする。【解決手段】上記の課題は,DNAポリメラーゼの校正機能を抑制した酵母の変異株を,少なくとも1%(v/v)以上の乳酸濃度下で培養した後,生存細胞を単離する工程を含む方法により乳酸耐性を有する酵母を得て,その酵母に,乳酸合成酵素遺伝子を導入することにより乳酸合成能も有する酵母を得て,乳酸を製造することにより解決される。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007050851A JP2010115112A (ja) | 2007-02-28 | 2007-02-28 | 酵母の製造方法,酵母,及び乳酸の製造方法 |
JP2007-050851 | 2007-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008105175A1 true WO2008105175A1 (ja) | 2008-09-04 |
Family
ID=39721017
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/000353 WO2008105175A1 (ja) | 2007-02-28 | 2008-02-26 | 酵母の製造方法,酵母,及び乳酸の製造方法 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JP2010115112A (ja) |
WO (1) | WO2008105175A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010068734A (ja) * | 2008-09-17 | 2010-04-02 | Toyota Central R&D Labs Inc | 乳酸の製造方法及び乳酸発酵用添加剤 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9217165B2 (en) | 2011-04-28 | 2015-12-22 | Toray Industries, Inc. | Mutant strain of lactic acid producing yeast and process for producing lactic acid |
DK3133164T3 (da) | 2014-04-14 | 2019-05-27 | Toray Industries | Fremgangsmåde til fremstilling af et kemisk stof ved kontinuerlig fermentering |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001204468A (ja) * | 2000-01-27 | 2001-07-31 | Toyota Motor Corp | 耐酸性乳酸生成微生物 |
JP2001516584A (ja) * | 1997-09-12 | 2001-10-02 | エイ・イー・スタリー・マニユフアクチヤリング・カンパニー | 乳酸生産のための酵母菌株 |
JP2003259878A (ja) * | 2002-03-11 | 2003-09-16 | Toyota Central Res & Dev Lab Inc | 乳酸脱水素酵素をコードするdnaおよびその利用 |
JP2007061024A (ja) * | 2005-08-31 | 2007-03-15 | Neo-Morgan Laboratory Inc | 乳酸耐性に優れた生物および乳酸耐性に優れた生物の作製方法 |
-
2007
- 2007-02-28 JP JP2007050851A patent/JP2010115112A/ja active Pending
-
2008
- 2008-02-26 WO PCT/JP2008/000353 patent/WO2008105175A1/ja active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001516584A (ja) * | 1997-09-12 | 2001-10-02 | エイ・イー・スタリー・マニユフアクチヤリング・カンパニー | 乳酸生産のための酵母菌株 |
JP2001204468A (ja) * | 2000-01-27 | 2001-07-31 | Toyota Motor Corp | 耐酸性乳酸生成微生物 |
JP2003259878A (ja) * | 2002-03-11 | 2003-09-16 | Toyota Central Res & Dev Lab Inc | 乳酸脱水素酵素をコードするdnaおよびその利用 |
JP2007061024A (ja) * | 2005-08-31 | 2007-03-15 | Neo-Morgan Laboratory Inc | 乳酸耐性に優れた生物および乳酸耐性に優れた生物の作製方法 |
Non-Patent Citations (1)
Title |
---|
TABATA K. ET AL.: "DNA Polymerase no Kosei Kino o Yokusei shita Shutsuga Kobo ni yoru Alkali Oyobi Nyusan Taisei no Kakutoku", JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY 2006 NENDO TAIKAI KOEN YOSHISHU, 5 March 2006 (2006-03-05), pages 310 + ABSTR. NO. 3C34P06 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010068734A (ja) * | 2008-09-17 | 2010-04-02 | Toyota Central R&D Labs Inc | 乳酸の製造方法及び乳酸発酵用添加剤 |
Also Published As
Publication number | Publication date |
---|---|
JP2010115112A (ja) | 2010-05-27 |
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