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WO2007113440A1 - Novel surfactant concentrate derived from alkyl polyglycosides and use thereof for preparing, without heating, cosmetic and/or pharmaceutical formulations - Google Patents

Novel surfactant concentrate derived from alkyl polyglycosides and use thereof for preparing, without heating, cosmetic and/or pharmaceutical formulations Download PDF

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Publication number
WO2007113440A1
WO2007113440A1 PCT/FR2007/051038 FR2007051038W WO2007113440A1 WO 2007113440 A1 WO2007113440 A1 WO 2007113440A1 FR 2007051038 W FR2007051038 W FR 2007051038W WO 2007113440 A1 WO2007113440 A1 WO 2007113440A1
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Prior art keywords
weight
mass
mixture
formula
composition
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PCT/FR2007/051038
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French (fr)
Inventor
Chantal Amalric
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Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic
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Publication of WO2007113440A1 publication Critical patent/WO2007113440A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/604—Alkylpolyglycosides; Derivatives thereof, e.g. esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair

Definitions

  • New tcnsioactive concentrate derived from alkyl polyglycosides and its use for preparing without heating, cosmetic and / or pharmaceutical formulations
  • the invention relates to the provision of new emulsifying concentrates that can be used in the preparation of cosmetic and / or pharmaceutical formulations, in particular for topical use.
  • Emulsifiers derived from sugar have been developed for more than twenty years and their commercial success is well established. These commercial compositions consisting of a mixture of alkyl polyglycosides and fatty alcohols, are on the market in solid form, whether flakes, powder or pearls. They must therefore be melted before being incorporated into the final formulation, which in some cases constitutes a brake on their commercial expansion. Such emulsifiers are described in international applications published under the numbers WO 92/06778, WO 95/13863 or WO 96/37285.
  • the international application WO 92/06778 also discloses, by way of example 1, a cream containing 25% of a mixture comprising 87.2% of cetylstearyl alcohol (C 16 -C 18 ), 12.2% of cetearyl glucosides and 0.6 % glucose and 75% water, having a viscosity of about 25,000 mPa.s at 20 ° C and a milk containing 5% of a mixture comprising 87.2% cetyl stearyl alcohol (C16- C18), 12.2% of cetearyl glucosides and 0.6% of glucose and 95% of water, having a viscosity of about 3200 mPa.s at 20 ° C, said cream and said milk having been prepared for verify the self-emulsifiable nature of the mixture of fatty alcohol and alkyl polysaccharide used.
  • the international application WO 95/13863 discloses by its example 7 a mixture consisting of 70% water and 30% of a mixture (M 1 ) consisting of 0.1% by weight. weight of decanol, 0.1% by weight of dodecanol, 1.4% by weight of tetradecanol, 8.9% by weight of hexadecanol, 19.9% by weight of octadecanol, 8.2% by weight of % by weight of decyl polyglucoside, 6.8% by weight of dodecyl polyglucoside, 14.9% by weight of tetradecyl polyglucoside, 21.6% by weight of hexadecyl polyglucoside and 18.1% by weight of octadecyl polyglucoside. Said mixture is prepared and immediately used to prepare a liquid soap.
  • This same patent application discloses by its example 4 discloses three aqueous dispersions containing 85% water and:
  • composition (C) comprising for 100% of its mass:
  • RA-OH in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms or a mixture of compounds of formulas (IA)
  • composition (C) is not a composition (C 0 ) containing for 100% of its mass, 95% by weight of water and 5% by weight of a mixture (M 0 ) comprising for 100% of its mass, 87.2% by weight of cetylstearyl alcohol, 12.2% by weight of cetearyl glucoside and 0.6% of glucose.
  • topically acceptable aqueous solvent denotes in the definition of the composition (C), the solvents conventionally used in cosmetics and / or pharmaceuticals, whether it be, for example, aqueous solutions of ethanol or isopropanol, aqueous solutions of polyols such as, for example, water-glycol, water-glycerol, water-diglycerol, water-sorbitol, water-xylitol, water-erythritol, water-AQUAXYL TM (mixture of xylitylglucoside, anhydroxylitol and xylitol), water-propylene glycol, water-butylene glycol, pentylene glycol water, water-hexylene glycol.
  • polyols such as, for example, water-glycol, water-glycerol, water-diglycerol, water-sorbitol, water-xylitol, water-erythritol, water-AQUAXYL TM (
  • R A in the formulas (I A ) and (H A ) is especially an alkyl radical. comprising from 16 to 24 carbon atoms, and more particularly a radical chosen from hexadecyl, octadecyl, eicosyl or docosyl radicals;
  • linear saturated hydrocarbon radical containing from 8 to 14 carbon atoms is meant in particular for R B in the formulas (I B) and (It), an alkyl radical containing from 8 to 14 carbon atoms, more particularly a radical selected from radicals, octyl decyl, dodecyl or tetradecyl.
  • residue of a reducing sugar is meant in particular in the definition of compounds of formulas (H A ) and (II), as defined above, the remains of glucose, sucrose, fructose, idose, galactose , maltose, maltotriose, lactose, cellobiose, mannose, xylose, Farabinose, ribose, dextran or tallose.
  • x is a decimal number which represents the average degree of polymerization of the residue G.
  • (G) x is the polymeric residue of rank x of the remainder G.
  • x is between 1.05 and 5, and more particularly between 1.05 and 2.
  • topically acceptable preserving agents in the composition (C) as defined above, is meant agents usually used in topical cosmetic and / or pharmaceutical formulations, for example benzoic acid, its salts and its esters, propionic acid and its derivatives. salts, salicylic acid and its salts, sorbic acid and its salts, formaldehyde, inorganic sulphites and bisulfites, chlorobutanol, parahydroxybenzoic acids, their salts and esters, undecylenic acid and its salts, bromo 2 nitro2 propane diol 1-3, diazolidinyl urea, SEPICIDE TM CI (Imidazolidinyl urea), SEPICIDE TM LD (Phenoxyethanol), SEPICIDE TM HB (Phenoxyethanol blend of methylparaben, propylparaben and butylparaben ethylparaben), KATHON TM CG (mixture of methylchloroisothiazolinone
  • composition (C) as defined above characterized in that when said mixture (M) comprises a non-zero proportion of compound of formula (I B ), the mass ratio: Compounds of formula (I A ) / Compounds of formula (I B ), is greater than 1 and more particularly greater than or equal to 5.
  • a composition (C) as defined above characterized in that when said mixture (M) comprises a non-zero proportion of compound of formula (II), the ratio Mass: Compounds of formula (HA) / Compounds of formula (II), is greater than or equal to 0.75.
  • composition (C) characterized in that it comprises for 100% of its mass:
  • RA-OH (IA) in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms or a mixture of compounds of formulas
  • topically acceptable preservative up to 3% by weight of a topically acceptable preservative or a mixture of topically acceptable preservatives.
  • composition (C) as defined above comprises for 100% of its mass:
  • the subject of the invention is a cosmetic and / or pharmaceutical formulation for topical use, characterized in that it comprises, as emulsifier, from 2% to 30% by weight of a composition (C) as defined previously.
  • a composition C
  • examples of such a formulation are, for example, emulsions intended to be impregnated on wipes, hygiene products such as bubble baths or "oil-in-water” emulsions.
  • wet emulsions are very fluid emulsions for impregnating paper / textile media.
  • the wipes manufacturing process is carried out in specific industrial units which are often far removed from the traditional units for preparing cosmetic emulsions and have on site only tanks of mixtures equipped with simple mixers and without the possibility of heating.
  • the use of the composition (C) as defined above, makes it possible to prepare in these simple and unheated tanks emulsions by simple mixing with water and the other additives of the emulsion such as the fatty phase, the perfume, the conservative or assets.
  • the composition (C) as defined above is implemented in the absence of heating which simplifies the process and increases the productivity compared to the process according to the state of the art.
  • cream-gels As oil-in-water emulsions, there are the formulas called cream-gels. These formulas consist of a liquid fatty phase and an aqueous phase stabilized by the presence of a polymer and are therefore generally free of waxes. Production processes are carried out without heating, which shortens manufacturing times and increases productivity. Moreover, such processes are very interesting for formulating heat-sensitive active agents such as dihydroxyacetone, magnesium ascorbyl phosphate, tocopherols and their derivatives, hydrogen peroxide, essential oils, more generally all the oxidizable molecules used as active in cosmetics or pharmacy for topical use.
  • the composition (C) as defined above is introduced easily into the cream-gels to provide the recognized contribution of alkyl polyglucosides, namely a better feel, without losing the advantages of the cream gel process which is a method without heating.
  • the subject of the invention is a process for the preparation of a cosmetic and / or pharmaceutical formulation for topical use, characterized in that from 2% to 30% by weight of a composition (C) is incorporated therein. ) as defined above.
  • the preparation of the formulation is carried out by simple mixing at room temperature, all of its constituents.
  • the subject of the invention is the use of a composition (C) as defined previously as an emulsifying agent in a cosmetic and / or pharmaceutical formulation for topical use.
  • topical use as used in the definitions of the formulation, process and use as defined above, means that said formulation is implemented by application to the skin, scalp, hair or the mucous membranes, whether it is a direct application in the case of a cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical composition or an indirect application for example in the case of a personal care product in the form of a textile or paper towel or sanitary products intended to be in contact with the skin or the mucous membranes.
  • composition (C 1 ) is prepared comprising for 100% of its mass: 1% by mass of SEPICIDE TM HB, 94% by weight of water and 5% of a mixture M 1 comprising for 100% of its mass : from 30% by weight to 40% by weight of eicosanol, from 30% by weight to 40% by weight of docosanol, from 7% by weight to 8% by weight of tetradecanol; 5.5% by mass to 7.5% by weight of compound of formula (II A) wherein R A represents an eicosyl group, G represents a glucose residue and x is between 1.05 and 2, 5.5 mass% to 7.5% by weight of compound of formula (H A ) in which R A represents a docosyl radical, G represents a glucose residue and x is between 1.05 and 2; from 2 wt% to 4 wt% of the compound of formula (H A ) in which R A represents a tetradecyl radical, G represents a glucose residue and x is between 1.05
  • composition (C 1 ) is stable for 1 year at room temperature and does not sediment after centrifugation for 30 minutes at 3000 rpm (Sigma TM centrifuge type 4- 15).
  • SIMULGEL TM NS is a self reversing inverse latex of sodium acryloyldimethyl taurate and hydroyxyethylacrylate in squalane and comprising polysorbate 60, sold by the company SEPPIC.
  • composition (C 2 ) is prepared comprising, for 100% of its mass: 0.08% by weight of KATHON TM CG, 89.9% by weight of water and 10% of an M 2 mixture comprising 100% by weight. % of its mass, 40% by mass to 45% by mass of eicosanol, 40% by mass to 45% by mass of docosanol, 5% by mass to 10% by weight of compound of formula (II a) wherein R a is eicosyl radical, G represents a glucose residue and x is between 1.05 and 2, from 5% by mass to 10% by weight of compound of formula (H A ) in which R A represents a docosyl radical, G represents a residue of glucose and x is between 1.05 and 2, simply by hot mixing the mixture M 2 , the preservative and water.
  • a shower gel is prepared from a composition (C 2 ):
  • LYTRON TM 631 a mixture containing a copolymer of sodium acrylate and styrene, sodium lauryl sulfate and trideceth-7.
  • KATHON TM CG mixture of methylchloroisothiazolinone and methylisothiazolinone sold by the company Rohm & Haas.
  • composition (C 3 ) is prepared comprising for 100% of its mass: 1% by weight of EUXYL TM PE9010, 91% by weight of water and 8% of a M 3 mixture comprising for 100% of its mass: from 30% by weight to 35% by weight of hexadecanol, from 30% by weight to 35% by weight of octadecanol; from 5 wt.% to 10 wt.% of compound of formula (H A ) wherein R A is hexadecyl, G is glucose and x is from 1.05 to 2, 5 wt.% to 10 wt.% (instead of 5% by mass to 10% by weight) of compound of formula (H A ) in which R A represents an octadecyl radical, G represents a glucose residue and x is between 1.05 and 2; from 10 wt% to 15 wt% of the compound of formula (II) wherein R A represents a dodecyl radical, G represents a
  • a body milk is prepared from a composition (C 3 )
  • SEPIPLUS TM 400 is a self-invertible inverse latex of polyacrylates in polyisobutene and comprising polysorbate 20, sold by the company SEPPIC.
  • EUXYL TM PE 9010 is a preservative containing phenoxyethanol and ethylhexylglycerin.
  • This table shows that it is possible to prepare cold formulations with the composition C 3 having a homogeneous character of the same order as those prepared hot with the mixture (M 3 ), but with a preparation time that is twice as short . It may also be noted that the formulation 7 has the characteristics of a better feel and finesse than an identical formulation without C 3 .
  • composition (C 4 ) is prepared comprising for 100% of its mass: 75% by weight of a mixture of water: butylene glycol 50:50 and 25% of a mixture M 4 comprising for 100% of its mass from 35 wt.% to 40 wt.% hexadecanol, from 35 wt.% to 40 wt.% octadecanol, from 10 wt.% to 14 wt.% of the compound of formula (H A ) wherein R A is hexadecyl, G represents a residue of xylose and x is between 1.05 and 2, from 10% by mass to 14% by weight of compound of formula (H A ) in which R A represents an octadecyl radical, G represents a residue of xylose and x is between 1.05 and 2, simply by hot mixing the mixture M 4 and water mixture: butylene glycol.
  • a self-tanning sprayable lotion formula (C 4 ) is prepared from a composition (C 4 )
  • SIMULGEL TM FL is a self-invertible inverse latex of sodium acryloyldimethyl taurate and of hydroyxyethylacrylate in isohexadecane and comprising polysorbate 60, sold by the company SEPPIC.
  • composition C 4 having a homogeneous character of the same order as those prepared hot with the mixture (M 4 ), but with a preparation time twice as much. short. It may also be noted that the formulation has the characteristic of being perfectly compatible with DHA.
  • Example 5 Preparation of a composition (CO intended for face-frothing gels (a) -
  • a composition (C 5 ) is prepared comprising for 100% of its mass: 1.0% by weight of MONTALINE TM C40, 79.0% by weight of water and 20% of a mixture (M 5 ) comprising for 100% of its mass, from 35% by weight to 40% by weight of octadecanol, from 35% by weight to 40% by mass of hexadecanol, from 15% by mass to 20% by weight of compound of formula (II) in which R B represents a dodecyl radical, G represents a glucose residue and x is between 1.05 and 2, from 5% by mass to 10% by weight of compound of formula (II) in which R B represents a tetradecyl radical, G represents a residue; of glucose and x is between 1.05 and 2 by simple hot mixing of the mixture M 5 , the pseudo-preservative and water.
  • a foaming face gel is prepared from a composition (C 5 ):
  • PROTEOL TM APL is a surfactant derived from amino acids
  • This table shows that it is possible to prepare cold formulations with the composition C 5 having a homogeneous character of the same order as those prepared hot with the mixture (M 5 ), but with a shorter preparation time of A quarter. It may further be noted that the formulation 13 has, as features, a better feel of foam and better tolerance than an identical formulation without C 5 .
  • composition (C 6 ) comprising 100% of its mass is prepared: 1% by weight of phenoxyethanol, 84% by weight of a mixture of water - AQUAXYL TM (70 - 30) and 15% of a mixture M 6 comprising, per 100% of its mass, 5% by mass to 10% by mass of docosanol, 5% by mass to 10% by mass of eicosanol, 75% by mass to 80% by weight of compound of formula (II A) wherein R A represents a docosyl radical, G represents a glucose residue and x is between 1.05 and 2, from 5 wt% to 10 wt% of compound of formula (H A ) in which R A represents an eicosyl radical, G represents a glucose residue and x is between 1.05 and 2 by simple hot mixing of the M 6 mixture, the preservative and water.
  • SEPESfO V TM EMT10 is a powder polymer based on acryloyldimethyl taurate, sold by the company SEPPIC.
  • This table shows that it is possible to prepare cold formulations with the composition C 6 having a homogeneous character of the same order as those prepared for warm with the mixture (M 6 ), but with a preparation time twice as short. It may be noted that such a process is particularly advantageous in the presence of easily oxidizable and heat-alterable active agents such as magnesium ascorbyl phosphate.

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Abstract

Composition (C) comprising: from 70% to 98% by mass of water or of an aqueous solvent, from 2% to 30% by mass of a mixture (M) comprising: from 5% to 95% by mass of an alcohol of formula (IA): RA-OH in which the RA radical is a saturated linear hydrocarbon-based radical containing from 16 to 24 carbon atoms; optionally, up to 47.5% by mass of an alcohol of formula (IB), RB-OHin which the RB radical is a saturated linear hydrocarbon-based radical containing from 8 to 14 carbon atoms; from 5% to 95% by mass of a compound of formula (IIA): RA-O-(G)XH in which the RA radical is a saturated linear hydrocarbon-based radical containing from 16 to 24 carbon atoms, G is the residue of a reducing sugar and x is a decimal number greater than or equal to 1 and less than or equal to 10; optionally, up to 47.5% by mass of a compound of formula (IIB), RB-O-(G)XH in which the RB radical is a saturated linear hydrocarbon-based radical containing from 8 to 14 carbon atoms, G is the residue of a reducing sugar and x is a decimal number greater than or equal to 1 and less than or equal to 10; and in which the ratio by mass: compounds of formula (IA)/compounds of formula (IIA), is greater than or equal to 2.5; and, optionally, up to 3% by mass of a preserving agent; formulation for topical use containing same, and use of the composition (C) as emulsifier.

Description

Nouveau concentré tcnsioactif issu d'alkyl polyglycosides, et son utilisation pour préparer sans chauffage, des formulations cosmétiques et/ou pharmaceutiques New tcnsioactive concentrate derived from alkyl polyglycosides, and its use for preparing without heating, cosmetic and / or pharmaceutical formulations
L'invention concerne la fourniture de nouveaux concentrés émulsionnants utilisables dans la préparation de formulations cosmétiques et/ou pharmaceutiques notamment à usage topique.The invention relates to the provision of new emulsifying concentrates that can be used in the preparation of cosmetic and / or pharmaceutical formulations, in particular for topical use.
Les agents émulsionnants dérivés de sucre ont été développés depuis plus d'une vingtaine d'année et leur succès commercial n'est plus à démontrer. Ces compositions commerciales constituées d'un mélange d'alkyl polyglycosides et d'alcools gras, se présentent sur le marché sous forme solide, qu'il s'agisse d'écaillés, de poudre ou de perles. Ils doivent donc préalablement être fondus, avant d'être incorporés dans la formulation finale, ce qui dans certains cas constitue un frein à leur expansion commerciale. De tels agents émulsionnants sont décrits dans les demandes internationales publiées sous les numéros WO 92/06778, WO 95/13863 ou WO 96/37285.Emulsifiers derived from sugar have been developed for more than twenty years and their commercial success is well established. These commercial compositions consisting of a mixture of alkyl polyglycosides and fatty alcohols, are on the market in solid form, whether flakes, powder or pearls. They must therefore be melted before being incorporated into the final formulation, which in some cases constitutes a brake on their commercial expansion. Such emulsifiers are described in international applications published under the numbers WO 92/06778, WO 95/13863 or WO 96/37285.
On a donc naturellement cherché à développer des mélanges d'alkyl polyglycosides et d'alcools gras qui soient liquides à température ordinaire, pour éviter cette opération de fusion lors de la préparation de la formulation finale. Pour cela, on a utilisé des alcools gras ramifiés ou insaturés pour conduire à de tels mélanges. De tels agents émulsionnants liquides sont décrits dans la demande internationale publiée sous le numéro WO 00/56438 ou encore dans la demande de brevet français publiée sous le numéro FR 2 830 464. De telles compositions liquides, à cause de leur caractère très lipophile, ne permettent pas la préparation d'émulsions huile - dans - eau suffisamment stables et/ou présentant un toucher suffisamment satisfaisant pour le client final.It has therefore naturally sought to develop mixtures of alkyl polyglycosides and fatty alcohols which are liquid at ordinary temperature, to avoid this melting operation during the preparation of the final formulation. For this, branched or unsaturated fatty alcohols were used to lead to such mixtures. Such liquid emulsifiers are described in the international application published under the number WO 00/56438 or in the French patent application published under the number FR 2 830 464. Such liquid compositions, because of their very lipophilic character, do not do not allow the preparation of oil - in - water emulsions which are sufficiently stable and / or have a sufficiently satisfactory feel for the final customer.
La demande internationale WO 92/06778 divulgue aussi par son exemple 1 une crème contenant 25% d'un mélange comprenant 87,2% d'alcool cétylstéarylique (C16- C18), 12,2% de cétéaryl glucosides et 0,6% de glucose et 75% d'eau, présentant une viscosité d'environ 25 000 mPa.s à 20°C ainsi qu'un lait contenant 5% d'un mélange comprenant 87,2% d'alcool cétyl stéarylique (C16-C18), 12,2% de cétéaryl glucosides et 0,6% de glucose et 95% d'eau, présentant une viscosité d'environ 3 200 mPa.s à 20°C, ladite crème et le dit lait ayant été préparé pour vérifier le caractère auto-émulsionnable du mélange alcool gras, alkyl polyoside mis en œuvre.The international application WO 92/06778 also discloses, by way of example 1, a cream containing 25% of a mixture comprising 87.2% of cetylstearyl alcohol (C 16 -C 18 ), 12.2% of cetearyl glucosides and 0.6 % glucose and 75% water, having a viscosity of about 25,000 mPa.s at 20 ° C and a milk containing 5% of a mixture comprising 87.2% cetyl stearyl alcohol (C16- C18), 12.2% of cetearyl glucosides and 0.6% of glucose and 95% of water, having a viscosity of about 3200 mPa.s at 20 ° C, said cream and said milk having been prepared for verify the self-emulsifiable nature of the mixture of fatty alcohol and alkyl polysaccharide used.
La demande internationale WO 95/13863 divulgue par son exemple 7 un mélange constitué de 70% d'eau et de 30% d'un mélange (M1) constitué de 0,1% en poids de décanol, de 0,1% en poids de dodécanol, de 1,4% en poids de tétradécanol, de 8,9% en poids d'hexadécanol, de 19,9% en poids d'octadécanol, de 8,2% en poids de décyl polyglucoside, de 6,8 % en poids de dodécyl polyglucoside, de 14,9% en poids de tétradécyl polyglucoside, de 21,6% en poids d'hexadécyl polyglucoside et de 18,1% en poids d'octadécyl polyglucoside. Ledit mélange est préparé et immédiatement utilisé pour préparer un savon liquide. Cette même demande de brevet divulgue par son exemple 4 divulgue trois dispersions aqueuses contenant 85% d'eau et :The international application WO 95/13863 discloses by its example 7 a mixture consisting of 70% water and 30% of a mixture (M 1 ) consisting of 0.1% by weight. weight of decanol, 0.1% by weight of dodecanol, 1.4% by weight of tetradecanol, 8.9% by weight of hexadecanol, 19.9% by weight of octadecanol, 8.2% by weight of % by weight of decyl polyglucoside, 6.8% by weight of dodecyl polyglucoside, 14.9% by weight of tetradecyl polyglucoside, 21.6% by weight of hexadecyl polyglucoside and 18.1% by weight of octadecyl polyglucoside. Said mixture is prepared and immediately used to prepare a liquid soap. This same patent application discloses by its example 4 discloses three aqueous dispersions containing 85% water and:
15% dudit mélange M1 (dispersion 1),15% of said mixture M 1 (dispersion 1),
15% d'un mélange M2 constitué de 33,5% d'alcool cétylique, de 33,5% d'alcool stéarylique, de 28,2% de décyl polyglucoside, de 2,4% de dodécyl polyglucoside, de 2,4% de tétradécyl polyglucoside (dispersion (2), et15% of a mixture M 2 consisting of 33.5% of cetyl alcohol, 33.5% of stearyl alcohol, 28.2% of decyl polyglucoside, 2.4% of dodecyl polyglucoside, 2, 4% tetradecyl polyglucoside (dispersion (2), and
15% d'un mélange M3 constitué de 25% d'hexadécanol, de 25% en poids d'octadécanol, de 25% de d'hexadécyl polyglucoside, et de 25% en poids d'octadécyl polyglucoside (dispersion 3).15% of a mixture M 3 consisting of 25% hexadecanol, 25% by weight octadecanol, 25% hexadecyl polyglucoside, and 25% by weight octadecyl polyglucoside (dispersion 3).
Ce même exemple 4 divulgue que la dispersion 1 est stable 1 mois, alors que la dispersion 2 n'est stable que 1 jour et que la dispersion 3 n'est stable que pendant 7 jours.This same example 4 discloses that the dispersion 1 is stable for 1 month, whereas the dispersion 2 is stable for only 1 day and that the dispersion 3 is stable only for 7 days.
Dans le cadre de leur recherches sur l'amélioration constante des agents émulsionnants pour préparer des émulsions "huile dans eau" qui soient dépourvus des inconvénients cités plus haut, les inventeurs ont mis au point un nouveau concentré émulsionnant.As part of their research on the constant improvement of the emulsifiers to prepare "oil-in-water" emulsions which have none of the disadvantages mentioned above, the inventors have developed a new emulsifying concentrate.
Selon un premier aspect, l'invention a pour objet une composition (C) comprenant pour 100% de sa masse :According to a first aspect, the subject of the invention is a composition (C) comprising for 100% of its mass:
- de 70% massique à 98% massique et plus particulièrement, de 80% massique à 98% massique d'eau ou d'un solvant aqueux topiquement acceptable,from 70 wt% to 98 wt% and more particularly from 80 wt% to 98 wt% water or a topically acceptable aqueous solvent,
- de 2% massique à 30% massique et plus particulièrement de 2% massique à 20% massique d'un mélange (M) comprenant pour 100% de sa masse :from 2% by weight to 30% by weight and more particularly from 2% by weight to 20% by weight of a mixture (M) comprising for 100% of its mass:
- de 5% massique à 95% massique d'un alcool de formule (IA) :from 5% by mass to 95% by weight of an alcohol of formula (I A ):
RA-OH (IA) dans laquelle le radical RA représente un radical hydrocarboné linéaire saturé comportant de 16 à 24 atomes de carbone ou d'un mélange de composés de formules (IA)RA-OH (IA) in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms or a mixture of compounds of formulas (IA)
- éventuellement jusqu'à 47,5% massique d'un alcool de formule (IB),optionally up to 47.5% by weight of an alcohol of formula (I B ),
RB-OH (IB) dans laquelle le radical RB représente un radical hydrocarboné linéaire saturé comportant de 8 à 14 atomes de carbone, ou d'un mélange de composés de formules (IB) ;R B -OH (I B ) in which the radical R B represents a saturated linear hydrocarbon radical containing from 8 to 14 carbon atoms, or a mixture of compounds of formulas (IB);
- de 5% massique à 95% massique d'un composés de formule (HA) :- from 5% by mass to 95% by mass of a compound of formula (II A):
RA-O-(G)XH (HA) dans laquelle le radical RA représente un radical hydrocarboné linéaire saturé comportant de 16 à 24 atomes de carbone, G représente le reste d'un sucre réducteur et x représente un nombre décimal supérieur ou égal à 1 et inférieur ou égal à 10, ou d'un mélange de composés de formules (HA),R A -O- (G) X H (H A ) in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms, G represents the remainder of a reducing sugar and x represents a decimal number greater than or equal to 1 and less than or equal to 10, or a mixture of compounds of formulas (H A ),
- éventuellement jusqu'à 47,5% massique d'un composé de formule (HB),optionally up to 47.5% by weight of a compound of formula (II B ),
RB-O-(G)XH (HB) dans laquelle le radical RB représente un radical hydrocarboné linéaire saturé comportant de 8 à 14 atomes de carbone, G représente le reste d'un sucre réducteur et x représente un nombre décimal supérieur ou égal à 1 et inférieur ou égal à 10, ou d'un mélange de composés de formules (IB) ; et dans lequel le rapport massique : Composés de formule (IA) / Composés de formule (HA) est supérieur ou égal à 2,5 et plus particulièrement supérieur ou égal à 3 ; et si désiré ou si nécessaire :R B -O- (G) X H (H B ) in which the radical R B represents a saturated linear hydrocarbon radical containing from 8 to 14 carbon atoms, G represents the remainder of a reducing sugar and x represents a decimal number greater than or equal to 1 and less than or equal to 10, or a mixture of compounds of formulas (I B ); and wherein the weight ratio: Compounds of formula (I A ) / Compounds of formula (H A ) is greater than or equal to 2.5 and more particularly greater than or equal to 3; and if desired or necessary:
- jusqu'à 3% massique d'un agent conservateur topiquement acceptable ou d'un mélange d'agents conservateurs topiquement acceptables ; étant entendu que la composition (C) n'est pas une composition (C0) contenant pour 100% de sa masse, 95% massique d'eau et 5% massique d'un mélange (M0) comprenant pour 100% de sa masse, 87,2% massique d'alcool cétylstéarylique, 12,2% massique de cétéaryl glucoside et 0,6% de glucose.up to 3% by weight of a topically acceptable preservative or a mixture of topically acceptable preservatives; it being understood that the composition (C) is not a composition (C 0 ) containing for 100% of its mass, 95% by weight of water and 5% by weight of a mixture (M 0 ) comprising for 100% of its mass, 87.2% by weight of cetylstearyl alcohol, 12.2% by weight of cetearyl glucoside and 0.6% of glucose.
Par solvant aqueux topiquement acceptable, on désigne dans la définition de la composition (C), les solvants classiquement utilisés en cosmétique et /ou en pharmacie, qu'il s'agisse par exemple de solutions aqueuses d'éthanol ou d'isopropanol, de solutions aqueuses de polyols comme par exemple les mélanges eau-glycol, eau-glycérol, eau- diglycérol, eau-sorbitol, eau-xylitol, eau-érythritol, eau-AQUAXYL™ (mélange de xylitylglucoside, d'anhydroxylitol et de xylitol), eau-propylèneglycol, eau- butylèneglycol, eau pentylèneglycol, eau-hexylèneglycol.The term "topically acceptable aqueous solvent" denotes in the definition of the composition (C), the solvents conventionally used in cosmetics and / or pharmaceuticals, whether it be, for example, aqueous solutions of ethanol or isopropanol, aqueous solutions of polyols such as, for example, water-glycol, water-glycerol, water-diglycerol, water-sorbitol, water-xylitol, water-erythritol, water-AQUAXYL ™ (mixture of xylitylglucoside, anhydroxylitol and xylitol), water-propylene glycol, water-butylene glycol, pentylene glycol water, water-hexylene glycol.
Par radical hydrocarboné linéaire saturé comportant de 16 à 24 atomes de carbone, on désigne notamment pour RA dans les formules (IA) et (HA), un radical alkyle comportant de 16 à 24 atomes de carbone, et plus particulièrement un radical choisi parmi les radicaux hexadécyle, octadécyle, eicosyle ou docosyleBy saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms, R A in the formulas (I A ) and (H A ) is especially an alkyl radical. comprising from 16 to 24 carbon atoms, and more particularly a radical chosen from hexadecyl, octadecyl, eicosyl or docosyl radicals;
Par radical hydrocarboné linéaire saturé comportant de 8 à 14 atomes, on désigne notamment pour RB dans les formules (IB) et (Ils), un radical alkyle comportant de 8 à 14 atomes de carbone, et plus particulièrement un radical choisi parmi les radicaux, octyle décyle, dodécyle ou tétradécyle.By linear saturated hydrocarbon radical containing from 8 to 14 carbon atoms, is meant in particular for R B in the formulas (I B) and (It), an alkyl radical containing from 8 to 14 carbon atoms, more particularly a radical selected from radicals, octyl decyl, dodecyl or tetradecyl.
Par reste d'un sucre réducteur, on désigne notamment dans la définition des composés de formules (HA) et (Ils), telle que définie précédemment, les restes du glucose, du saccharose, du fructose, de l'idose, du galactose, du maltose, du maltotriose, du lactose, du cellobiose, du mannose, du xylose, de Farabinose, du ribose, du dextrane ou du tallose.By residue of a reducing sugar, is meant in particular in the definition of compounds of formulas (H A ) and (II), as defined above, the remains of glucose, sucrose, fructose, idose, galactose , maltose, maltotriose, lactose, cellobiose, mannose, xylose, Farabinose, ribose, dextran or tallose.
Selon un autre aspect particulier de la présente invention, par reste d'un sucre, on désigne dans la définition des composés de formules (HA) et (Ils), telle que définie précédemment, définie précédemment les restes du glucose, du xylose ou de l'arabinose.According to another particular aspect of the present invention, by the remainder of a sugar, in the definition of the compounds of formulas (H A ) and (II), as defined above, defined previously the residues of glucose, xylose or arabinose.
Dans la définition des formules (HA) et (Ils) telle que définie précédemment, x est un nombre décimal qui représente le degré moyen de polymérisation du reste G. Lorsque x est un nombre entier, (G)x est le reste polymérique de rang x du reste G. Lorsque x est un nombre décimal, les formules (HA) et (Ils) représentent respectivement un mélange de composés : ai RA-O-G-H + a2 RA-O-(G)2-H + a3 RA-O-(G)3-H + ... + a, RA-O-(G)q-H avec q représentant un nombre entier compris entre 1 et 10 et dans les proportions molaires ai, a2, a3,... aq telles que : q=lIn the definition of the formulas (H A ) and (II) as defined above, x is a decimal number which represents the average degree of polymerization of the residue G. When x is an integer, (G) x is the polymeric residue of rank x of the remainder G. When x is a decimal number, the formulas (H A ) and (They) respectively represent a mixture of compounds: ai R A -OGH + a 2 R A -O- (G) 2 -H + a 3 R A -O- (G) 3 -H + ... + a, R A -O- (G) q -H with q representing an integer between 1 and 10 and in the molar proportions ai, a 2 , a 3 , ... aq such that: q = l
∑ aq= 1 ; ai > O q=10 et un mélange de composés : bi RBO-G-H + b2 RBO-(G)2-H + b3 RBO-(G)3-H + ... + bq RBO-(G)q-H avec q représentant un nombre entier compris entre 1 et 10 et dans les proportions molaires bi, b2, b3,... bq telles que : q=l
Figure imgf000007_0001
q=10Σ aq = 1; ai> O q = 10 and a mixture of compounds: bi R B OGH + b 2 R B O- (G) 2 -H + b 3 R B O- (G) 3 -H + ... + b q R B O- (G) q -H with q representing an integer between 1 and 10 and in the molar proportions bi, b 2 , b 3 , ... b q such that: q = l
Figure imgf000007_0001
q = 10
Selon un autre aspect particulier de la présente invention, dans la définition des composés de formules (HA) et (Ils), x est compris entre 1,05 et 5, et plus particulièrement entre 1,05 et 2.According to another particular aspect of the present invention, in the definition of the compounds of formulas (HA) and (II), x is between 1.05 and 5, and more particularly between 1.05 and 2.
Par agents conservateurs topiquement acceptables, on désigne dans la composition (C) telle que définie précédemment des agents habituellement utilisés dans les formulations cosmétiques et/ou pharmaceutiques topiques, par exemple l'acide benzoïque ses sels et ses esters, l'acide propionique et ses sels, l'acide salicylique et ses sels, l'acide sorbique et ses sels, le formaldehyde, les sulfites et bisulfites inorganiques, le chlorobutanol, les acides parahydroxybenzoïques leurs sels et esters, l'acide undecylénique et ses sels, le bromo 2 nitro2 propane diol 1-3, le diazolidinyl urée, le SEPICIDE™ CI (Imidazolidinyl urée), le SEPICIDE™ LD (Phenoxyethanol), le SEPICIDE™ HB (mélange de Phenoxyethanol de Méthylparaben, d'éthylparaben de propylparaben et de butylparaben), le KATHON™ CG (mélange de méthylchloroisothiazolinone et de méthylisothiazolinone), L'EUXYL™ PE9010 (mélange de phenoxyethanol et d'éthylhexylglycérine), le SEPICIDE™ LD (Phenoxyethanol), le SEPICIDE™ HB (mélange de Phenoxyethanol de Méthylparaben, d'éthylparaben de propylparaben et de butylparaben), le KATHON™ CG (mélange de méthylchloroisothiazolinone et de méthylisothiazolinone), L'EUXYL™ PE 9010 (mélange de phenoxyethanol et d'éthylhexylglycérine), le SENSIVA™ SC 50 (éthyl hexyl glycérine), le MONTALINE™ C40 (cocamidopropyl betainamide mea chloride), Le PROTEOL™ APL (tensioactif dérivé d'acides aminés) le Quaternium 15, l'alcool benzylique, le methyl dibromoglutaronitrile, le digluconate de chlorhexidine, le glutaraldehyde, la chlorphenesine, le sodium hydroxyméthyl glycinate, le chlorure de benzthonium ou le iodopropynyl butyl carbamate.By topically acceptable preserving agents, in the composition (C) as defined above, is meant agents usually used in topical cosmetic and / or pharmaceutical formulations, for example benzoic acid, its salts and its esters, propionic acid and its derivatives. salts, salicylic acid and its salts, sorbic acid and its salts, formaldehyde, inorganic sulphites and bisulfites, chlorobutanol, parahydroxybenzoic acids, their salts and esters, undecylenic acid and its salts, bromo 2 nitro2 propane diol 1-3, diazolidinyl urea, SEPICIDE ™ CI (Imidazolidinyl urea), SEPICIDE ™ LD (Phenoxyethanol), SEPICIDE ™ HB (Phenoxyethanol blend of methylparaben, propylparaben and butylparaben ethylparaben), KATHON ™ CG (mixture of methylchloroisothiazolinone and methylisothiazolinone), EUXYL ™ PE9010 (mixture of phenoxyethanol and ethylhexylglycerine), SEPICIDE ™ LD (Phenoxyethanol), SEPICIDE ™ HB (Phenoxyethanol blend of methylparaben, propylparaben ethylparaben and butylparaben), KATHON ™ CG (mixture of methylchloroisothiazolinone and methylisothiazolinone), EUXYL ™ PE 9010 (mixture of phenoxyethanol and ethylhexylglycerine), SENSIVA ™ SC 50 (ethyl hexyl glycerine), MONTALINE ™ C40 (cocamidopropyl betainamide mea chloride), PROTEOL ™ APL (amino acid derived surfactant) Quaternium 15, benzyl alcohol, methyl dibromoglutaronitrile, chlorhexidine digluconate glutaraldehyde, chlorphenesine, sodium hydroxymethyl glycinate, benzthonium chloride or iodopropynyl butyl carbamate.
Selon un autre aspect particulier de la présente invention, celle-ci a pour objet une composition (C) telle que définie précédemment caractérisée en ce que lorsque ledit mélange (M) comprend une proportion non nulle de composé de formule (IB), le rapport massique : Composés de formule (IA) / Composés de formule (IB), est supérieur à 1 et plus particulièrement, supérieur ou égal à 5. Selon un autre aspect particulier de la présente invention, celle-ci a pour objet une composition (C) telle que définie précédemment caractérisée en ce que lorsque ledit mélange (M) comprend une proportion non nulle de composé de formule (Ils), le rapport massique : Composés de formule (HA) / Composés de formule (Ils), est supérieur ou égal à 0,75.According to another particular aspect of the present invention, it relates to a composition (C) as defined above characterized in that when said mixture (M) comprises a non-zero proportion of compound of formula (I B ), the mass ratio: Compounds of formula (I A ) / Compounds of formula (I B ), is greater than 1 and more particularly greater than or equal to 5. According to another particular aspect of the present invention, it relates to a composition (C) as defined above characterized in that when said mixture (M) comprises a non-zero proportion of compound of formula (II), the ratio Mass: Compounds of formula (HA) / Compounds of formula (II), is greater than or equal to 0.75.
Selon un autre aspect particulier de la présente invention, celle-ci a pour objet une composition (C) caractérisée en ce qu'elle comprend pour 100% de sa masse :According to another particular aspect of the present invention, it relates to a composition (C) characterized in that it comprises for 100% of its mass:
- de 80% massique à 98% massique d'eau,from 80% by weight to 98% by weight of water,
- de 2% massique à 20% massique d'un mélange (M) comprenant pour 100% de sa masse :from 2% by weight to 20% by weight of a mixture (M) comprising for 100% of its mass:
- de 5% massique à 95% massique d'un alcool de formule (IA) :from 5% by mass to 95% by weight of an alcohol of formula (I A ):
RA-OH (IA) dans laquelle le radical RA représente un radical hydrocarboné linéaire saturé comportant de 16 à 24 atomes de carbone ou d'un mélange de composés de formulesRA-OH (IA) in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms or a mixture of compounds of formulas
(IA) ;(IA);
- de 5% massique à 95% massique d'un composé de formule (HA) :from 5% by mass to 95% by weight of a compound of formula (H A ):
RA-O-(G)XH (HA) dans laquelle le radical RA représente un radical hydrocarboné linéaire saturé comportant de 16 à 24 atomes de carbone, G représente le reste d'un sucre réducteur et x représente un nombre décimal supérieur ou égal à 1 et inférieur ou égal à 10, ou d'un mélange de composés de formules (HA) ; et si désiré ou si nécessaire :R A -O- (G) X H (H A ) in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms, G represents the remainder of a reducing sugar and x represents a decimal number greater than or equal to 1 and less than or equal to 10, or a mixture of compounds of formulas (HA); and if desired or necessary:
- jusqu'à 3% massique d'un agent conservateur topiquement acceptable ou d'un mélange d'agents conservateurs topiquement acceptables.up to 3% by weight of a topically acceptable preservative or a mixture of topically acceptable preservatives.
Selon un autre aspect particulier, la composition (C) telle que définie précédemment, comprend pour 100% de sa masse :According to another particular aspect, the composition (C) as defined above, comprises for 100% of its mass:
- de 85% massique à 95% massique d'eau, et de 5% massique à 15% massique dudit mélange (M) et tout particulièrement :from 85% by mass to 95% by weight of water, and from 5% by mass to 15% by weight of said mixture (M) and very particularly:
- de 87,5% massique à 92,5% massique d'eau, et de 7,5% massique à 12,5% massique dudit mélange (M).from 87.5% by weight to 92.5% by weight of water, and from 7.5% by weight to 12.5% by weight of said mixture (M).
Selon un autre aspect, l'invention a pour objet une formulation cosmétique et/ ou pharmaceutique à usage topique, caractérisée en ce qu'elle comprend comme agent émulsionnant, de 2% à 30% massique d'une composition (C) telle que définie précédemment. Comme exemples d'une telle formulation, il y a par exemple les émulsions destinées à être imprégnées sur des lingettes, les produits d'hygiène tels que les bains-moussants ou les émulsions "huile dans eau".According to another aspect, the subject of the invention is a cosmetic and / or pharmaceutical formulation for topical use, characterized in that it comprises, as emulsifier, from 2% to 30% by weight of a composition (C) as defined previously. Examples of such a formulation are, for example, emulsions intended to be impregnated on wipes, hygiene products such as bubble baths or "oil-in-water" emulsions.
Les émulsions lingettes sont des émulsions très fluides destinées à imprégner des supports papier/textile. Le procédé de fabrication des lingettes est réalisé dans des unités industrielles spécifiques qui souvent sont éloignées des unités traditionnelles de préparation d'émulsions cosmétiques et ne comportent sur place que des cuves de mélanges équipées de mélangeurs simples et sans possibilité de chauffage. L'utilisation de la composition (C) telle que définie précédemment, permet de préparer dans ces cuves simples et non chauffées des émulsions par simple mélange avec l'eau et les autres additifs de l'émulsion comme la phase grasse, le parfum, le conservateur ou les actifs.Wet emulsions are very fluid emulsions for impregnating paper / textile media. The wipes manufacturing process is carried out in specific industrial units which are often far removed from the traditional units for preparing cosmetic emulsions and have on site only tanks of mixtures equipped with simple mixers and without the possibility of heating. The use of the composition (C) as defined above, makes it possible to prepare in these simple and unheated tanks emulsions by simple mixing with water and the other additives of the emulsion such as the fatty phase, the perfume, the conservative or assets.
Dans la fabrication de formulations moussantes (bains moussants, shampoings, gels-douche), la composition (C) telle que définie précédemment, est mise en œuvre en l'absence de chauffage ce qui simplifie le procédé et augmente la productivité par rapport au procédé selon l'état de la technique.In the manufacture of foaming formulations (foaming baths, shampoos, shower gels), the composition (C) as defined above, is implemented in the absence of heating which simplifies the process and increases the productivity compared to the process according to the state of the art.
Comme émulsions huile dans eau, il y a les formules appelées gels-crème. Ces formules constituées par une phase grasse liquide et une phase aqueuse stabilisée grâce à la présence d'un polymère et sont donc en général dépourvues de cires. Les procédés de production sont réalisés sans chauffage, ce qui raccourcit les temps de fabrication et augmente la productivité. Par ailleurs, de tels procédés sont très intéressants pour formuler des actifs sensibles à la chaleur tels que la dihydroxyacétone, le magnésium ascorbyl phosphate, les tocophérols et leurs dérivés, l'eau oxygénée, les huiles essentielles, plus généralement toutes les molécules oxydables utilisées comme actif en cosmétique ou pharmacie à usage topique. La composition (C) telle que définie précédemment est introduite facilement dans les gels-crème pour apporter la contribution reconnue des alkyl polyglucosides, à savoir un meilleur toucher, sans néanmoins perdre les avantages du procédé des gels crèmes qui est un procédé sans chauffage.As oil-in-water emulsions, there are the formulas called cream-gels. These formulas consist of a liquid fatty phase and an aqueous phase stabilized by the presence of a polymer and are therefore generally free of waxes. Production processes are carried out without heating, which shortens manufacturing times and increases productivity. Moreover, such processes are very interesting for formulating heat-sensitive active agents such as dihydroxyacetone, magnesium ascorbyl phosphate, tocopherols and their derivatives, hydrogen peroxide, essential oils, more generally all the oxidizable molecules used as active in cosmetics or pharmacy for topical use. The composition (C) as defined above is introduced easily into the cream-gels to provide the recognized contribution of alkyl polyglucosides, namely a better feel, without losing the advantages of the cream gel process which is a method without heating.
Selon un autre aspect, l'invention a pour objet un procédé de préparation d'une formulation cosmétique et / ou pharmaceutique à usage topique, caractérisé en ce que l'on y incorpore de 2% à 30% massique d'une composition (C) telle que définie précédemment. Dans le procédé tel que défini précédemment, la préparation de la formulation est réalisée par simple mélange à température ambiante, de l'ensemble de ses constituants.According to another aspect, the subject of the invention is a process for the preparation of a cosmetic and / or pharmaceutical formulation for topical use, characterized in that from 2% to 30% by weight of a composition (C) is incorporated therein. ) as defined above. In the process as defined above, the preparation of the formulation is carried out by simple mixing at room temperature, all of its constituents.
Selon un dernier aspect, l'invention a pour objet l'utilisation d'une composition (C) telle que définie précédemment comme agent émulsionnant dans une formulation cosmétique et / ou pharmaceutique à usage topique.According to a last aspect, the subject of the invention is the use of a composition (C) as defined previously as an emulsifying agent in a cosmetic and / or pharmaceutical formulation for topical use.
L'expression "à usage topique" utilisée dans les définitions de la formulation, du procédé et de l'utilisation tels que définis ci-dessus, signifie que ladite formulation est mise en œuvre par application sur la peau, le cuir chevelu, les cheveux ou les muqueuses, qu'il s'agisse d'une application directe dans le cas d'une composition cosmétique, dermocosmétique, dermo-pharmaceutique ou pharmaceutique ou d'une application indirecte par exemple dans le cas d'un produit d'hygiène corporelle sous forme de lingette en textile ou en papier ou de produits sanitaires destinés à être en contact avec la peau ou les muqueuses.The term "topical use" as used in the definitions of the formulation, process and use as defined above, means that said formulation is implemented by application to the skin, scalp, hair or the mucous membranes, whether it is a direct application in the case of a cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical composition or an indirect application for example in the case of a personal care product in the form of a textile or paper towel or sanitary products intended to be in contact with the skin or the mucous membranes.
Les exemples suivants illustrent l'invention sans toutefois la limiter. Exemple 1 : Préparation d'une composition (Ci) destinée à des formules d'imprégnation lingettesThe following examples illustrate the invention without limiting it. Example 1 Preparation of a Composition (Ci) for Wet Impregnation Formulas
(a) - On prépare une composition (C1) comprenant pour 100% de sa masse : 1% massique de SEPICIDE™ HB, 94% massique d'eau et 5% d'un mélange M1 comprenant pour 100% de sa masse : de 30% massique à 40% massique d'eicosanol, de 30% massique à 40% massique de docosanol, de 7% massique à 8% massique de tétradécanol ; de 5,5% massique à 7,5% massique de composé de formule (HA) dans laquelle RA représente un radical eicosyle, G représente un reste de glucose et x est compris entre 1,05 et 2, de 5,5% massique à 7,5% massique de composé de formule (HA) dans laquelle RA représente un radical docosyle, G représente un reste de glucose et x est compris entre 1,05 et 2 ; de 2% massique à 4% massique de composé de formule (HA) dans laquelle RA représente un radical tétradécyle, G représente un reste de glucose et x est compris entre 1,05 et 2, et de 2% massique à 4% massique de composé de formule (HA) dans laquelle RA représente un radical dodécyle, G représente un reste de glucose et x est compris entre 1,05 et 2, par simple mélange à chaud du mélange M1, de l'agent conservateur et de l'eau. Sa viscosité finale est de 15 000 mPas : Brookfield LV (Mobile : 4 ; V : 6 tours / minute). La composition (C1) est stable pendant 1 an à température ambiante et ne se sédimente pas après centrifugation pendant 30 minutes à 3000 tours minute (centrifugeuse Sigma™ type 4- 15).(a) - A composition (C 1 ) is prepared comprising for 100% of its mass: 1% by mass of SEPICIDE ™ HB, 94% by weight of water and 5% of a mixture M 1 comprising for 100% of its mass : from 30% by weight to 40% by weight of eicosanol, from 30% by weight to 40% by weight of docosanol, from 7% by weight to 8% by weight of tetradecanol; 5.5% by mass to 7.5% by weight of compound of formula (II A) wherein R A represents an eicosyl group, G represents a glucose residue and x is between 1.05 and 2, 5.5 mass% to 7.5% by weight of compound of formula (H A ) in which R A represents a docosyl radical, G represents a glucose residue and x is between 1.05 and 2; from 2 wt% to 4 wt% of the compound of formula (H A ) in which R A represents a tetradecyl radical, G represents a glucose residue and x is between 1.05 and 2, and from 2% by weight to 4% mass of compound of formula (H A ) in which R A represents a dodecyl radical, G represents a glucose residue and x is between 1.05 and 2, by simple hot mixing of the M 1 mixture, of the preserving agent. and water. Its final viscosity is 15,000 mPas: Brookfield LV (Mobile: 4, V: 6 rpm). The composition (C 1 ) is stable for 1 year at room temperature and does not sediment after centrifugation for 30 minutes at 3000 rpm (Sigma ™ centrifuge type 4- 15).
(b) - On prépare une formule d'imprégnation lingettes à partir d'une composition (Ci)(b) - A wipe impregnation formula is prepared from a composition (Ci)
Figure imgf000011_0001
Figure imgf000011_0001
SIMULGEL™ NS est un latex inverse auto - inversible d'acryloyldiméthyl taurate de sodium et d'hydroyxyéthylacrylate dans le squalane et comportant du polysorbate 60, commercialisé par la société SEPPIC.SIMULGEL ™ NS is a self reversing inverse latex of sodium acryloyldimethyl taurate and hydroyxyethylacrylate in squalane and comprising polysorbate 60, sold by the company SEPPIC.
Ce tableau met en évidence que l'on peut préparer des formulations à froid avec la composition C1 ayant un caractère homogène du même ordre que celles préparés à chaud avec le mélange (M1), mais avec un temps de préparation deux fois plus court. On peut aussi noter que la formulation 1 présente comme caractéristiques, un meilleur toucher, une plus grande finesse, un meilleur effet démaquillant qu'une formulation identique sans C1. Exemple 2 : Préparation d'une composition (Ci) destinée à des gels-douchesThis table shows that it is possible to prepare cold formulations with the composition C 1 having a homogeneous character of the same order as those prepared in warm with the mixture (M 1 ), but with a preparation time twice as short. It may also be noted that formulation 1 has characteristics, a better feel, a greater fineness, a better cleansing effect than an identical formulation without C 1 . Example 2 Preparation of a Composition (Ci) for Shower Gels
(a) - On prépare une composition (C2) comprenant pour 100% de sa masse : 0,08% massique de KATHON™ CG, 89,9% massique d'eau et 10% d'un mélange M2 comprenant pour 100% de sa masse, de 40% massique à 45% massique d'eicosanol, de 40% massique à 45% massique de docosanol, de 5% massique à 10% massique de composé de formule (HA) dans laquelle RA représente un radical eicosyle, G représente un reste de glucose et x est compris entre 1,05 et 2, de 5% massique à 10% massique de composé de formule (HA) dans laquelle RA représente un radical docosyle, G représente un reste de glucose et x est compris entre 1,05 et 2, par simple mélange à chaud du mélange M2, de l'agent conservateur et de l'eau. Sa viscosité finale est de 20 000 mPa s : Brookfield LV (Mobile : 4 ; Vitesse : 6 tours / minute). La composition (C2) est stable pendant 1 an à température ambiante et ne se sédimente pas après centrifugation pendant 30 minutes à 3000 tours minute (centrifugeuse Sigma™ type 4- 15).(a) - A composition (C 2 ) is prepared comprising, for 100% of its mass: 0.08% by weight of KATHON ™ CG, 89.9% by weight of water and 10% of an M 2 mixture comprising 100% by weight. % of its mass, 40% by mass to 45% by mass of eicosanol, 40% by mass to 45% by mass of docosanol, 5% by mass to 10% by weight of compound of formula (II a) wherein R a is eicosyl radical, G represents a glucose residue and x is between 1.05 and 2, from 5% by mass to 10% by weight of compound of formula (H A ) in which R A represents a docosyl radical, G represents a residue of glucose and x is between 1.05 and 2, simply by hot mixing the mixture M 2 , the preservative and water. Its final viscosity is 20,000 mPa s: Brookfield LV (Mobile: 4, Speed: 6 rpm). The composition (C 2 ) is stable for 1 year at room temperature and does not sediment after centrifugation for 30 minutes at 3000 rpm (Sigma ™ centrifuge type 4- 15).
(b) - On prépare un gel-douche à partir d'une composition (C2) : (b) - A shower gel is prepared from a composition (C 2 ):
Figure imgf000013_0001
Figure imgf000013_0001
LYTRON™ 631 : mélange contenant un copolymère d'acrylate de sodium et de styrène, du lauryl sulfate de sodium et du trideceth-7. KATHON™CG : mélange de méthylchloroisothiazolinone et de méthylisothiazolinone commercialisé par la société ROHM & HAAS.LYTRON ™ 631: a mixture containing a copolymer of sodium acrylate and styrene, sodium lauryl sulfate and trideceth-7. KATHON ™ CG: mixture of methylchloroisothiazolinone and methylisothiazolinone sold by the company Rohm & Haas.
Ce tableau met en évidence que l'on peut préparer des formulations à froid avec la composition C2 ayant un caractère homogène du même ordre que celles préparées à chaud avec le mélange (M2), mais avec un temps de préparation deux fois plus court. On peut noter par ailleurs que la formulation 4 présente comme caractéristiques un meilleur toucher de mousse et une meilleure tolérance qu'une formulation identique sans C2 Exemple 3 : Préparation d'une composition (CV) destinée à des soins corporelsThis table shows that it is possible to prepare cold formulations with the composition C 2 having a homogeneous character of the same order as those prepared hot with the mixture (M 2 ), but with a preparation time that is twice as short . It may further be noted that the formulation 4 has as characteristics a better feel of foam and a better tolerance than an identical formulation without C 2. Example 3: Preparation of a composition (CV) intended for body care
(a) - On prépare une composition (C3) comprenant pour 100% de sa masse : 1% massique d'EUXYL™ PE9010, 91% massique d'eau et 8% d'un mélange M3 comprenant pour 100% de sa masse : de 30% massique à 35% massique d'hexadécanol, de 30% massique à 35% massique d'octadécanol ; de 5% massique à 10% massique de composé de formule (HA) dans laquelle RA représente un radical hexadécyle, G représente un reste de glucose et x est compris entre 1,05 et 2, de 5% massique à 10% massique (plutôt de 5% massique à 10% massique) de composé de formule (HA) dans laquelle RA représente un radical octadécyle, G représente un reste de glucose et x est compris entre 1,05 et 2 ; de 10% massique à 15% massique de composé de formule (Ils) dans laquelle RA représente un radical dodécyle, G représente un reste de glucose et x est compris entre 1,05 et 2, et de 3% massique à 5% massique de composé de formule (Ils) dans laquelle RA représente un radical tétradécyle, G représente un reste de glucose et x est compris entre 1,05 et 2, par simple mélange à chaud du mélange M3, de l'agent conservateur et de l'eau.(a) - A composition (C 3 ) is prepared comprising for 100% of its mass: 1% by weight of EUXYL ™ PE9010, 91% by weight of water and 8% of a M 3 mixture comprising for 100% of its mass: from 30% by weight to 35% by weight of hexadecanol, from 30% by weight to 35% by weight of octadecanol; from 5 wt.% to 10 wt.% of compound of formula (H A ) wherein R A is hexadecyl, G is glucose and x is from 1.05 to 2, 5 wt.% to 10 wt.% (instead of 5% by mass to 10% by weight) of compound of formula (H A ) in which R A represents an octadecyl radical, G represents a glucose residue and x is between 1.05 and 2; from 10 wt% to 15 wt% of the compound of formula (II) wherein R A represents a dodecyl radical, G represents a glucose residue and x is from 1.05 to 2, and from 3 wt% to 5 wt% of compound of formula (II) in which R A represents a tetradecyl radical, G represents a glucose residue and x is between 1.05 and 2, by simple hot mixing of the M 3 mixture, of the preserving agent and of the water.
Sa viscosité finale est de 15 000 mPa s (Brookfield LV Mobile : 4 ; Volume : 6 tours / minute). La composition (C3) est stable pendant 1 an à température ambiante et ne se sédimente pas après centrifugation pendant 30 minutes à 3000 tours minute (centrifugeuse Sigma™ type 4- 15).Its final viscosity is 15,000 mPa s (Brookfield LV Mobile: 4, Volume: 6 rpm). The composition (C 3 ) is stable for 1 year at room temperature and does not sediment after centrifugation for 30 minutes at 3000 rpm (Sigma ™ centrifuge type 4- 15).
(b) - On prépare un lait corporel à partir d'une composition (C3) (b) - A body milk is prepared from a composition (C 3 )
Figure imgf000015_0001
Figure imgf000015_0001
Le SEPIPLUS™ 400 est un latex inverse auto - inversible de polyacrylates dans le polyisobutene et comportant du polysorbate 20, commercialisé par la société SEPPIC. L'EUXYL™ PE 9010 est un agent conservateur contenant du phenoxyéthanol et de 1 ' éthy lhexy lgly cérine .SEPIPLUS ™ 400 is a self-invertible inverse latex of polyacrylates in polyisobutene and comprising polysorbate 20, sold by the company SEPPIC. EUXYL ™ PE 9010 is a preservative containing phenoxyethanol and ethylhexylglycerin.
Ce tableau met en évidence que l'on peut préparer des formulations à froid avec la composition C3 ayant un caractère homogène du même ordre que celles préparées à chaud avec le mélange (M3), mais avec un temps de préparation deux fois plus court. On peut aussi noter que la formulation 7 présente comme caractéristiques un meilleur toucher et une plus grande finesse qu'une formulation identique sans C3.This table shows that it is possible to prepare cold formulations with the composition C 3 having a homogeneous character of the same order as those prepared hot with the mixture (M 3 ), but with a preparation time that is twice as short . It may also be noted that the formulation 7 has the characteristics of a better feel and finesse than an identical formulation without C 3 .
Exemple 4 : Préparation d'une composition (C.) destinée à une lotion sprayablc autobronzanteEXAMPLE 4 Preparation of a composition (C) intended for a self-tanning sprayablc lotion
(a) - On prépare une composition (C4) comprenant pour 100% de sa masse : 75% massique d'un mélange eau : butylène glycol 50 :50 et 25% d'un mélange M4 comprenant pour 100% de sa masse, de 35% massique à 40% massique d'hexadécanol, de 35% massique à 40% massique d'octadécanol, de 10% massique à 14% massique de composé de formule (HA) dans laquelle RA représente un radical hexadécyle, G représente un reste de xylose et x est compris entre 1,05 et 2, de 10% massique à 14% massique de composé de formule (HA) dans laquelle RA représente un radical octadécyle, G représente un reste de xylose et x est compris entre 1,05 et 2, par simple mélange à chaud du mélange M4 et de mélange eau :butylène glycol.(a) - A composition (C 4 ) is prepared comprising for 100% of its mass: 75% by weight of a mixture of water: butylene glycol 50:50 and 25% of a mixture M 4 comprising for 100% of its mass from 35 wt.% to 40 wt.% hexadecanol, from 35 wt.% to 40 wt.% octadecanol, from 10 wt.% to 14 wt.% of the compound of formula (H A ) wherein R A is hexadecyl, G represents a residue of xylose and x is between 1.05 and 2, from 10% by mass to 14% by weight of compound of formula (H A ) in which R A represents an octadecyl radical, G represents a residue of xylose and x is between 1.05 and 2, simply by hot mixing the mixture M 4 and water mixture: butylene glycol.
Sa viscosité finale est d'environ 11 000 mPas : Brookfield LV (Mobile 3; Vitesse : 6 tours / minute). La composition (C4) est stable pendant 1 an à température ambiante et ne se sédimente pas après centrifugation pendant 30 minutes à 3000 tours minute (centrifugeuse Sigma™ type 4- 15).Its final viscosity is about 11,000 mPas: Brookfield LV (Mobile 3, Speed: 6 rpm). The composition (C 4 ) is stable for 1 year at room temperature and does not sediment after centrifugation for 30 minutes at 3000 rpm (Sigma ™ centrifuge type 4- 15).
(b) - On prépare une formule de lotion vaporisable ("sprayable" en langue anglaise) auto-bronzante à partir d'une composition (C4) (b) - A self-tanning sprayable lotion formula (C 4 ) is prepared from a composition (C 4 )
Figure imgf000017_0001
Figure imgf000017_0001
Le SIMULGEL™ FL est un latex inverse auto - inversible d'acryloyldiméthyl taurate de sodium et d'hydroyxyéthylacrylate dans Fisohexadecane et comportant du polysorbate 60, commercialisé par la société SEPPIC.SIMULGEL ™ FL is a self-invertible inverse latex of sodium acryloyldimethyl taurate and of hydroyxyethylacrylate in isohexadecane and comprising polysorbate 60, sold by the company SEPPIC.
Ce tableau met en évidence que l'on peut préparer des formulations à froid avec la composition C4 ayant un caractère homogène du même ordre que celles préparées à chaud avec le mélange (M4), mais avec un de temps de préparation deux fois plus court. On peut aussi noter que la formulation 10 présente comme caractéristique une parfaite compatibilité avec la DHA.This table shows that it is possible to prepare cold formulations with the composition C 4 having a homogeneous character of the same order as those prepared hot with the mixture (M 4 ), but with a preparation time twice as much. short. It may also be noted that the formulation has the characteristic of being perfectly compatible with DHA.
Exemple 5 : Préparation d'une composition (C-O destinée à des gels-moussants visage (a) - On prépare une composition (C5) comprenant pour 100% de sa masse : 1,0% massique de MONTALINE™ C40, 79,0% massique d'eau et 20% d'un mélange (M5) comprenant pour 100% de sa masse, de 35% massique à 40% massique d'octadécanol, de 35% massique à 40% massique d'hexadécanol, de 15% massique à 20% massique de composé de formule (Ils) dans laquelle RB représente un radical dodécyle, G représente un reste de glucose et x est compris entre 1,05 et 2, de 5% massique à 10% massique de composé de formule (Ils) dans laquelle RB représente un radical tetradécyle, G représente un reste de glucose et x est compris entre 1,05 et 2, par simple mélange à chaud du mélange M5, de l'agent pseudo-conservateur et de l'eau.Example 5 Preparation of a composition (CO intended for face-frothing gels (a) - A composition (C 5 ) is prepared comprising for 100% of its mass: 1.0% by weight of MONTALINE ™ C40, 79.0% by weight of water and 20% of a mixture (M 5 ) comprising for 100% of its mass, from 35% by weight to 40% by weight of octadecanol, from 35% by weight to 40% by mass of hexadecanol, from 15% by mass to 20% by weight of compound of formula (II) in which R B represents a dodecyl radical, G represents a glucose residue and x is between 1.05 and 2, from 5% by mass to 10% by weight of compound of formula (II) in which R B represents a tetradecyl radical, G represents a residue; of glucose and x is between 1.05 and 2 by simple hot mixing of the mixture M 5 , the pseudo-preservative and water.
Sa viscosité finale est d'environ 9 000 mPa s : Brookfield LV (Mobile : 4; V : 6 tours / minute). La composition (C5) est stable pendant 1 an à température ambiante et ne se sédimente pas après centrifugation pendant 30 minutes à 3000 tours minute (centrifugeuse Sigma™ type 4- 15).Its final viscosity is about 9,000 mPa s: Brookfield LV (Mobile: 4, V: 6 rpm). The composition (C 5 ) is stable for 1 year at room temperature and does not sediment after centrifugation for 30 minutes at 3000 rpm (Sigma ™ centrifuge type 4- 15).
(b) - On prépare un gel moussant visage à partir d'une composition (C5) : (b) - A foaming face gel is prepared from a composition (C 5 ):
Figure imgf000019_0001
Figure imgf000019_0001
Le PROTEOL™ APL est un tensioactif dérivé d'acides aminés,PROTEOL ™ APL is a surfactant derived from amino acids,
Ce tableau met en évidence que l'on peut préparer des formulations à froid avec la composition C5 ayant un caractère homogène du même ordre que celles préparées à chaud avec le mélange (M5), mais avec un temps de préparation plus court d'un quart. On peut noter par ailleurs que la formulation 13 présente comme caractéristiques, un meilleur toucher de mousse et une meilleure tolérance qu'une formulation identique sans C5.This table shows that it is possible to prepare cold formulations with the composition C 5 having a homogeneous character of the same order as those prepared hot with the mixture (M 5 ), but with a shorter preparation time of A quarter. It may further be noted that the formulation 13 has, as features, a better feel of foam and better tolerance than an identical formulation without C 5 .
Exemple 6 : Préparation d'une composition (Cf.) destinée à des crèmes de soinExample 6 Preparation of a Composition (Cf.) for Creams of Care
(a) - On prépare une composition (C6) comprenant pour 100% de sa masse : 1% massique de phenoxyethanol, 84% massique d'un mélange eau - AQUAXYL™ (70 - 30) et 15% d'un mélange M6 comprenant pour 100% de sa masse, de 5% massique à 10% massique de docosanol, de 5% massique à 10% massique d'eicosanol, de 75% massique à 80% massique de composé de formule (HA) dans laquelle RA représente un radical docosyle, G représente un reste de glucose et x est compris entre 1 ,05 et 2, de 5% massique à 10% massique de composé de formule (HA) dans laquelle RA représente un radical eïcosyle, G représente un reste de glucose et x est compris entre 1,05 et 2, par simple mélange à chaud du mélange M6, de l'agent conservateur et de l'eau.(a) - A composition (C 6 ) comprising 100% of its mass is prepared: 1% by weight of phenoxyethanol, 84% by weight of a mixture of water - AQUAXYL ™ (70 - 30) and 15% of a mixture M 6 comprising, per 100% of its mass, 5% by mass to 10% by mass of docosanol, 5% by mass to 10% by mass of eicosanol, 75% by mass to 80% by weight of compound of formula (II A) wherein R A represents a docosyl radical, G represents a glucose residue and x is between 1.05 and 2, from 5 wt% to 10 wt% of compound of formula (H A ) in which R A represents an eicosyl radical, G represents a glucose residue and x is between 1.05 and 2 by simple hot mixing of the M 6 mixture, the preservative and water.
Sa viscosité finale est d'environ 10 000 mPa s : Brookfield LV (Mobile 4 : ; V : 6 tours / minute). La composition (C6) est stable pendant 1 an à température ambiante et ne se sédimente pas après centrifugation pendant 30 minutes à 3000 tours minute (centrifugeuse Sigma™ type 4- 15).Its final viscosity is about 10,000 mPa s: Brookfield LV (Mobile 4: V: 6 rpm). The composition (C 6 ) is stable for 1 year at room temperature and does not sediment after centrifugation for 30 minutes at 3000 rpm (Sigma ™ centrifuge type 4- 15).
(b) - On prépare une crème hydratante anti-âge à partir d'une composition (C6) (b) - An anti-aging moisturizing cream is prepared from a composition (C 6 )
Figure imgf000021_0001
Figure imgf000021_0001
Le SEPESfO V™ EMT10 est un polymère poudre à base d'acryloyldimethyl taurate, commercialisé par la société SEPPIC.SEPESfO V ™ EMT10 is a powder polymer based on acryloyldimethyl taurate, sold by the company SEPPIC.
Ce tableau met en évidence que l'on peut préparer des formulations à froid avec la composition C6 ayant un caractère homogène du même ordre que celles préparées à chaud avec le mélange (M6), mais avec un temps de préparation deux fois plus court. On peut noter qu'un tel procédé est particulièrement intéressant en présence d'actif facilement oxydable et altérable à la chaleur comme le magnésium ascorbyl phosphate. This table shows that it is possible to prepare cold formulations with the composition C 6 having a homogeneous character of the same order as those prepared for warm with the mixture (M 6 ), but with a preparation time twice as short. It may be noted that such a process is particularly advantageous in the presence of easily oxidizable and heat-alterable active agents such as magnesium ascorbyl phosphate.

Claims

REVENDICATIONS
1. Composition (C) comprenant pour 100% de sa masse :1. Composition (C) comprising for 100% of its mass:
- de 70% massique à 98% massique d'eau ou d'un solvant aqueux topiquement acceptable,from 70% by weight to 98% by weight of water or of a topically acceptable aqueous solvent,
- de 2% massique à 30% massique d'un mélange (M) comprenant pour 100% de sa masse :from 2% by mass to 30% by weight of a mixture (M) comprising for 100% of its mass:
- de 5% massique à 95% massique d'un alcool de formule (IA) :from 5% by mass to 95% by weight of an alcohol of formula (I A ):
RA-OH (IA) dans laquelle le radical RA représente un radical hydrocarboné linéaire saturé comportant de 16 à 24 atomes de carbone ou d'un mélange de composés de formules (IA)RA-OH (IA) in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms or a mixture of compounds of formulas (IA)
- éventuellement jusqu'à 47,5% massique d'un alcool de formule (IB),optionally up to 47.5% by weight of an alcohol of formula (I B ),
RB-OH (IB) dans laquelle le radical RB représente un radical hydrocarboné linéaire saturé comportant de 8 à 14 atomes de carbone, ou d'un mélange de composés de formules (IB) ;R B -OH (I B ) in which the radical R B represents a saturated linear hydrocarbon radical containing from 8 to 14 carbon atoms, or a mixture of compounds of formulas (IB);
- de 5% massique à 95% massique d'un composé de formule (HA) :from 5% by mass to 95% by weight of a compound of formula (H A ):
RA-O-(G)XH (HA) dans laquelle le radical RA représente un radical hydrocarboné linéaire saturé comportant de 16 à 24 atomes de carbone, G représente le reste d'un sucre réducteur et x représente un nombre décimal supérieur ou égal à 1 et inférieur ou égal à 10, ou d'un mélange de composés de formules (HA),R A -O- (G) X H (H A ) in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms, G represents the remainder of a reducing sugar and x represents a decimal number greater than or equal to 1 and less than or equal to 10, or a mixture of compounds of formulas (H A ),
- éventuellement jusqu'à 47,5% massique d'un composé de formule (HB),optionally up to 47.5% by weight of a compound of formula (II B ),
RB-O-(G)XH (HB) dans laquelle le radical RB représente un radical hydrocarboné linéaire saturé comportant de 8 à 14 atomes de carbone, G représente le reste d'un sucre réducteur et x représente un nombre décimal supérieur ou égal à 1 et inférieur ou égal à 10, ou d'un mélange de composés de formules (IB) ; et dans lequel le rapport massique : Composés de formule (IA) / Composés de formuleR B -O- (G) X H (H B ) in which the radical R B represents a saturated linear hydrocarbon radical containing from 8 to 14 carbon atoms, G represents the remainder of a reducing sugar and x represents a decimal number greater than or equal to 1 and less than or equal to 10, or a mixture of compounds of formulas (I B ); and wherein the weight ratio: Compounds of formula (I A ) / Compounds of formula
(HA), est supérieur ou égal à 2,5 ; et si désiré ou si nécessaire :(H A ), is greater than or equal to 2.5; and if desired or necessary:
- jusqu'à 3% massique d'un agent conservateur topiquement acceptable ou d'un mélange d'agents conservateurs topiquement acceptables ; étant entendu que la composition (C) n'est pas une composition (C0) contenant pour 100% de sa masse, 95% massique d'eau et 5% massique d'un mélange (M0) comprenant pour 100% de sa masse, 87,2% massique d'alcool cétylstéarylique, 12,2% massique de cétéaryl glucoside et 0,6% de glucose.up to 3% by weight of a topically acceptable preservative or a mixture of topically acceptable preservatives; it being understood that the composition (C) is not a composition (C 0 ) containing for 100% of its mass, 95% by weight of water and 5% by weight of a mixture (M 0 ) comprising for 100% of its mass, 87.2% by weight of cetylstearyl alcohol, 12.2% by weight of cetearyl glucoside and 0.6% of glucose.
2. Composition (C) telle que définie à la revendication 1, comprenant pour 100% de sa masse :2. Composition (C) as defined in claim 1, comprising for 100% of its mass:
- de 80% massique à 98% massique d'eau, etfrom 80% by weight to 98% by weight of water, and
- de 2% massique à 20% massique dudit mélange (M)from 2% by weight to 20% by weight of said mixture (M)
3. Composition (C) telle que définie à l'une des revendications 1 ou 2, pour laquelle dans le mélange (M), le rapport massique : Composés de formule (IA) / Composés de formule (HA), est supérieur ou égal à 3.3. Composition (C) as defined in one of claims 1 or 2, wherein in the mixture (M), the mass ratio: Compounds of formula (I A ) / Compounds of formula (H A ), is greater or equal to 3.
4. Composition (C) telle que définie à l'une des revendications 1 à 3, pour laquelle, dans la définition des composés de formules (HA) et (Ils), (G) représente le reste du glucose, du xylose ou de l'arabinose.4. Composition (C) as defined in one of claims 1 to 3, for which, in the definition of compounds of formulas (H A ) and (They), (G) represents the rest of glucose, xylose or arabinose.
5. Composition (C) telle que définie à l'une des revendications 1 à 4, pour laquelle, dans la définition des composés de formules (HA) et (Ils), x est compris entre 1,05 et 5 et plus particulièrement entre 1,05 et 2.5. Composition (C) as defined in one of claims 1 to 4, for which, in the definition of compounds of formulas (H A ) and (II), x is between 1.05 and 5 and more particularly between 1.05 and 2.
6. Composition (C) telle que définie à l'une des revendications 1 à 5, caractérisée ne ce que lorsque ledit mélange (M) comprend une proportion non nulle de composé de formule (IB), le rapport massique : Composés de formule (IA) / Composés de formule (IB), est supérieur à 1 et plus particulièrement, supérieur ou égal à 5.6. Composition (C) as defined in one of claims 1 to 5, characterized only when said mixture (M) comprises a non-zero proportion of compound of formula (IB), the mass ratio: Compounds of formula ( IA) / Compounds of formula (I B ), is greater than 1 and more particularly greater than or equal to 5.
7. Composition (C) telle que définie à l'une des revendications 1 à 6, pour laquelle lorsque ledit mélange (M) comprend une proportion non nulle de composé de formule (HB), le rapport massique composé de formule (HA) / composé de formule (HB) est supérieur ou égal à 0,75.7. Composition (C) as defined in one of claims 1 to 6, wherein when said mixture (M) comprises a non-zero proportion of compound of formula (HB), the compound mass ratio of formula (HA) / compound of formula (HB) is greater than or equal to 0.75.
8. Composition (C) telle que définie à l'une des revendications 1 à 7, caractérisée en ce qu'elle comprend pour 100% de sa masse : - de 80% massique à 98% massique d'eau,8. Composition (C) as defined in one of claims 1 to 7, characterized in that it comprises for 100% of its mass: from 80% by weight to 98% by weight of water,
- de 2% massique à 20% massique d'un mélange (M) comprenant pour 100% de sa masse :from 2% by weight to 20% by weight of a mixture (M) comprising for 100% of its mass:
- de 5% massique à 95% massique d'un alcool de formule (IA) :from 5% by mass to 95% by weight of an alcohol of formula (I A ):
RA-OH (IA) dans laquelle le radical RA représente un radical hydrocarboné linéaire saturé comportant de 16 à 24 atomes de carbone ou d'un mélange de composés de formules (IA) ;RA-OH (IA) in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms or a mixture of compounds of formulas (IA);
- de 5% massique à 95% massique d'un composé de formule (HA) :from 5% by mass to 95% by weight of a compound of formula (H A ):
RA-O-(G)XH (HA) dans laquelle le radical RA représente un radical hydrocarboné linéaire saturé comportant de 16 à 24 atomes de carbone, G représente le reste d'un sucre réducteur et x représente un nombre décimal supérieur ou égal à 1 et inférieur ou égal à 10, ou d'un mélange de composés de formules (HA) ; et si désiré ou si nécessaire :R A -O- (G) X H (H A ) in which the radical R A represents a saturated linear hydrocarbon radical containing from 16 to 24 carbon atoms, G represents the remainder of a reducing sugar and x represents a decimal number greater than or equal to 1 and less than or equal to 10, or a mixture of compounds of formulas (H A ); and if desired or necessary:
- jusqu'à 3% massique d'un agent conservateur topiquement acceptable ou d'un mélange d'agents conservateurs topiquement acceptables.up to 3% by weight of a topically acceptable preservative or a mixture of topically acceptable preservatives.
9. Composition (C) telle que définie à l'une des revendications 1 à 8, comprenant pour 100% de sa masse :9. Composition (C) as defined in one of claims 1 to 8, comprising for 100% of its mass:
- de 85% massique à 95% massique d'eau, etfrom 85% to 95% by weight of water, and
- de 5% massique à 15% massique dudit mélange (M).from 5% by mass to 15% by weight of said mixture (M).
10. Composition (C) telle que définie à la revendication 9, comprenant pour 100% de sa masse :10. Composition (C) as defined in claim 9, comprising for 100% of its mass:
- de 87,5% massique à 92,5% massique d'eau, et- from 87.5% by mass to 92.5% by mass of water, and
- de 7,5% massique à 12,5% massique dudit mélange (M).from 7.5% by weight to 12.5% by weight of said mixture (M).
11. Formulation cosmétique et/ ou pharmaceutique à usage topique, caractérisée en ce qu'elle comprend comme agent émulsionnant, de 2% à 30% massique d'une composition (C) telle que définie à l'une des revendications 1 à 10. Cosmetic and / or pharmaceutical formulation for topical use, characterized in that it comprises, as emulsifier, from 2% to 30% by weight of a composition (C) as defined in one of Claims 1 to 10.
12. Préparation d'une formulation cosmétique et/ ou pharmaceutique à usage topique, caractérisé en ce que l'on y incorpore de 2% à 30% massique d'une composition (C) telle que définie à l'une des revendications 1 à 10.12. Preparation of a cosmetic and / or pharmaceutical formulation for topical use, characterized in that there is incorporated therein from 2% to 30% by weight of a composition (C) as defined in one of claims 1 to 10.
13. Utilisation d'une composition (C) telle que définie à l'une des revendications 1 à 10, comme agent émulsionnant dans une formulation cosmétique et/ ou pharmaceutique à usage topique. 13. Use of a composition (C) as defined in one of claims 1 to 10, as an emulsifying agent in a cosmetic and / or pharmaceutical topical formulation.
PCT/FR2007/051038 2006-03-31 2007-03-29 Novel surfactant concentrate derived from alkyl polyglycosides and use thereof for preparing, without heating, cosmetic and/or pharmaceutical formulations WO2007113440A1 (en)

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FR0651140A FR2899099A1 (en) 2006-03-31 2006-03-31 Composition, useful as emulsifying agent to prepare cosmetic and/or pharmaceutical formulation, comprises water, mixtures comprising e.g. alcohol compound and hydrocarbon compound and optionally a preservative

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017191394A1 (en) * 2016-05-04 2017-11-09 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Process for short-term improvement of the moisturization state of human skin epidermis; novel moisturizing compositions
WO2019025715A1 (en) 2017-08-02 2019-02-07 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Novel surfactant composition, production method thereof, and use of same as an emulsifier for the production of topical oil-in-water emulsions
CN111587105A (en) * 2017-12-12 2020-08-25 化工产品开发公司Seppic Novel alkyl polyrhamnossides, process for preparing same and cosmetic and/or pharmaceutical compositions containing same
JP2021505635A (en) * 2017-12-12 2021-02-18 ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピックＳｏｃｉｅｔｅ Ｄ’Ｅｘｐｌｏｉｔａｔｉｏｎ Ｄｅ Ｐｒｏｄｕｉｔｓ Ｐｏｕｒ Ｌｅｓ Ｉｎｄｕｓｔｒｉｅｓ Ｃｈｉｍｉｑｕｅｓ Ｓｅｐｐｉｃ Novel glyceryl polyramnosides, processes for preparing them, and cosmetic and / or pharmaceutical compositions containing them.
FR3137564A1 (en) 2022-07-06 2024-01-12 Thepenier Pharma & Cosmetics Aqueous cosmetic composition with fatty alcohol, saccharide ether, vegetable wax, non-silicone oil, amylose and/or amylopectin or starch.

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Publication number Priority date Publication date Assignee Title
FR3074685B1 (en) * 2017-12-12 2019-11-22 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic NOVEL POLYRHAMNOSID POLYOLS, PROCESS FOR THEIR PREPARATION AND COSMETIC AND / OR PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992006778A1 (en) * 1990-10-17 1992-04-30 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Use of fatty alcohol based compositions for preparing emulsions, method of preparing emulsions and emulsions so obtained
WO1996037285A1 (en) * 1995-05-24 1996-11-28 Societe D'exploitation De Produits Pour Les Industries Chimiques - Seppic Alkylpolyglycoside-based emulsifying composition and uses thereof
US5795978A (en) * 1995-11-15 1998-08-18 Henkel Kommanditgesellschaft Auf Aktien Emulsifiers
WO2000056438A1 (en) * 1999-03-19 2000-09-28 Societe D'exploitation De Produits Pour Les Industries Chimiques - S.E.P.P.I.C. Novel stable water-in-oil emulsions containing an emulsifier based on oleyl- and/or isostearyl-glycoside
FR2830464A1 (en) * 2001-10-05 2003-04-11 Seppic Sa Anhydrous oily liquid composition, useful in cosmetic, sanitary, agrochemical, pharmaceutical or veterinary applications, comprises a branched-chain alkyl polyxyloside and an oil phase
WO2003030838A1 (en) * 2001-10-11 2003-04-17 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Emulsifying compositions based on fatty alcohol and alkylpolyglycosides

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992006778A1 (en) * 1990-10-17 1992-04-30 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Use of fatty alcohol based compositions for preparing emulsions, method of preparing emulsions and emulsions so obtained
WO1996037285A1 (en) * 1995-05-24 1996-11-28 Societe D'exploitation De Produits Pour Les Industries Chimiques - Seppic Alkylpolyglycoside-based emulsifying composition and uses thereof
US5795978A (en) * 1995-11-15 1998-08-18 Henkel Kommanditgesellschaft Auf Aktien Emulsifiers
WO2000056438A1 (en) * 1999-03-19 2000-09-28 Societe D'exploitation De Produits Pour Les Industries Chimiques - S.E.P.P.I.C. Novel stable water-in-oil emulsions containing an emulsifier based on oleyl- and/or isostearyl-glycoside
FR2830464A1 (en) * 2001-10-05 2003-04-11 Seppic Sa Anhydrous oily liquid composition, useful in cosmetic, sanitary, agrochemical, pharmaceutical or veterinary applications, comprises a branched-chain alkyl polyxyloside and an oil phase
WO2003030838A1 (en) * 2001-10-11 2003-04-17 Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) Emulsifying compositions based on fatty alcohol and alkylpolyglycosides

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017191394A1 (en) * 2016-05-04 2017-11-09 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Process for short-term improvement of the moisturization state of human skin epidermis; novel moisturizing compositions
FR3050935A1 (en) * 2016-05-04 2017-11-10 Soc D'exploitation De Produits Pour Les Ind Chimiques Seppic METHOD FOR IMPROVING SHORT-TERM CONDITION OF HYDRATION OF HUMAN SKIN EPIDERM; NEW MOISTURIZING COMPOSITIONS
US10821060B2 (en) 2016-05-04 2020-11-03 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Process for short-term improvement of the moisturization state of human skin epidermis; novel moisturizing compositions
WO2019025715A1 (en) 2017-08-02 2019-02-07 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Novel surfactant composition, production method thereof, and use of same as an emulsifier for the production of topical oil-in-water emulsions
FR3069774A1 (en) * 2017-08-02 2019-02-08 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic NOVEL SURFACTANT COMPOSITION, PROCESS FOR PREPARING THE SAME, AND USE AS EMULSIFIER FOR PREPARING TOPICAL OIL-IN-WATER EMULSIONS
CN111065369A (en) * 2017-08-02 2020-04-24 化工产品开发公司Seppic Novel surfactant compositions, method for the production thereof and use thereof as emulsifiers for the production of topical oil-in-water emulsions
CN111587105A (en) * 2017-12-12 2020-08-25 化工产品开发公司Seppic Novel alkyl polyrhamnossides, process for preparing same and cosmetic and/or pharmaceutical compositions containing same
JP2021505635A (en) * 2017-12-12 2021-02-18 ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピックＳｏｃｉｅｔｅ Ｄ’Ｅｘｐｌｏｉｔａｔｉｏｎ Ｄｅ Ｐｒｏｄｕｉｔｓ Ｐｏｕｒ Ｌｅｓ Ｉｎｄｕｓｔｒｉｅｓ Ｃｈｉｍｉｑｕｅｓ Ｓｅｐｐｉｃ Novel glyceryl polyramnosides, processes for preparing them, and cosmetic and / or pharmaceutical compositions containing them.
JP7165733B2 (en) 2017-12-12 2022-11-04 ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピック Novel glyceryl polyrhamnosides, processes for their preparation and cosmetic and/or pharmaceutical compositions containing them
CN111587105B (en) * 2017-12-12 2023-07-21 化工产品开发公司Seppic New alkyl polyrhamnosides, process for their preparation and cosmetic and/or pharmaceutical compositions comprising them
FR3137564A1 (en) 2022-07-06 2024-01-12 Thepenier Pharma & Cosmetics Aqueous cosmetic composition with fatty alcohol, saccharide ether, vegetable wax, non-silicone oil, amylose and/or amylopectin or starch.

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