WO2007031291A2 - Foodstuff additive - Google Patents

Abstract

The invention relates to a foodstuff additive in particular for diets for a lasting adiposity therapy. The aim of said invention is to deliver a foodstuff additive for a lasting adiposity therapy for facilitating muscle-building and simultaneously fat-burning without excessive body training. For this purpose, the inventive foodstuff additive is based on a balanced aminoacid mixture whose quantitative ratio is nutritionally and physiologically optimal and which is supplemented with mineral salts containing 0.5-0.7g of calcium phosphate, 0.3-0.4 g of magnesium, 0.15-0.25 g of potassium, 0.04-0.06 of kelp which contains 7-8 mg iodine and oligoelements and from 0.15 to 0.25 g of lycopin-containing tomato extract. The totality of said indications is given in relation to 100 g of protein.

Description

 Zusatznahrunαsmittel

The invention relates to a supplementary foodstuff, in particular for use in diets for sustainable obesity therapy.

It is known from sports medicine that the intake of amino acids in combination with a calorie-reducing diet and exercise lead to weight reduction, without the reduction of muscle tissue, if at the same time intensively trained.

Normally, the body responds to dietary deficiencies in energy first by breaking down muscle tissue. Only then will the fat reserves of the body gradually be attacked. Responsible for this is u. a. the negative nitrogen balance. This is different if, at the same time as the diet, a balanced mix of amino acids that is immediately suitable for muscle growth is made available, and at the same time the muscle tissue is promoted through training. In this case, the administration of amino acids for the anabolic muscle tissue. At the same time an intensive fat burning takes place.

However, this desirable effect is significantly reduced if the accompanying training is less intense.

It is therefore an object of the invention to provide a suitable for sustainable obesity therapy, diet accompanying supplementary food, which promotes muscle growth with simultaneous fat burning, without having to rely on excessive exercise. The invention relates to a supplementary food, in particular for use in diets for sustainable obesity therapy, based on a mixture of amino acids, supplemented by

Mineral salts containing 0.5 g to 0.7 g of calcium phosphate, 0.3 g to 0.4 g of magnesium and 0.15 g to 0.25 g of potassium,

0.04 g to 0.06 g KeIp containing 7 mg to 8 mg iodine and trace elements, and

0.15 g to 0.25 g lycopene in the form of tomato extract.

(All weights are based on 100 g of protein).

The mass given in connection with the lycopene refers to the tomato extract in the whole, which contains lycopene. To obtain 1 kg of tomato extract, 20 - 25, preferably about 22 kg tomatoes are needed. The tomato extract is preferably in powder form. 1 kg of tomatoes contains about 20 mg of lycopene, whereas the content of lycopene in mature tomatoes can be significantly higher at 39-56 mg per 1 kg of tomatoes. More lycopene contain canned tomatoes: about 100 mg per 1 kg of tomatoes. The total amount of lycopene is therefore preferably between 0.05 mg and 0.2 mg, in particular 0.066 mg and 0.11 mg.

In principle, it is of course also possible to add lycopene in an appropriate amount, which was obtained from other sources.

It has surprisingly been found that by adding the indicated mineral salts and the substances contained in KeIp (iodine and trace elements) in conjunction with a balanced, nutritionally physiologically optimized amino acid mixture, the metabolism of the body is stimulated extremely intense, which otherwise only by physical Training induced stimulation to build muscle is substituted to a large extent. It comes so even without intensive training to build of muscle tissue and breakdown of adipose tissue. However, the training can not be completely replaced. However, it can be reduced to an appropriate level for the respective patient.

The addition of the antioxidant lycopene limits the oxidative damage caused by the increased metabolism. Lycopene is a radical scavenger that can neutralize radicals in the human body and thus significantly reduce the likelihood of certain cancers, such as prostate and lung cancer. Such free radicals are increasingly produced in a diet. In particular, lycopene is one of the most potent natural quenchers for singlet oxygen that can oxidize amino acids in proteins, nucleic acids and unsaturated fatty acids. Lycopene is a carotenoid found in tomatoes, rose hips, grapefruit, chanterelles and guavas and is rapidly absorbed by the intestine.

The KeIp is derived from brown algae and is rich in calcium, iodine, iron, alkali and minerals. Particularly preferred is the use of Ascophyllum nodosum as brown algae from the Fucales family. Ascophyllum nodosum contains iodine u. a. a larger amount of alginates capable of binding toxic heavy metal ions in the gut and digesting them. The KeIp is preferably used as a fine powder with a grain size of about 250 microns. A typical composition in% of the dry matter is:

In the organism, iodine plays a major role in the production of thyroid hormones. It has been found that the high iodine content in the KeIp helps reduce unwanted fat. The high content of iron, which is indispensable for the oxygenation of the tissue, strengthens the organism.

The additional food according to the invention is also well suited for the correction of malnutrition. Magnesium deficiency can trigger cardiac arrhythmia and convulsions in humans. Especially with low carbohydrate diet and diets and athletes there is an increased risk of magnesium deficiency.

Phosphates are essential for all living things. In particular, phosphate radicals constitute constituents of DNA and RNA molecules. Phosphorus compounds (ATP, ADP, etc.) also play a special role in metabolism. Calcium phosphates are among the main components of the skeletal substances of bones and teeth.

Magnesium and potassium may, for. B. be used in the form of magnesium oxide and potassium bicarbonate.

The amino acid mixture used for the supplementary food according to the invention preferably contains

L-Alanine 8.7 g +/- 10%

L-arginine 8,15 g +/- 10% L-aspartic acid 6 g +/- 10%

L-glutamic acid 11, 1 g +/- 10%

L-Glycine 20.6 g +/- 10%

L-histidine 0.6 g +/- 10%

L-hydroxylysine 1 g +/- 10% L-hydroxyproline 11, 4 g +/- 10% L-isoleucine 1, 6 g +/- 10%

L-leucine 3.3 g +/- 10%

L-lysine 3.9 g +/- 10%

L-methionine 0.6 g +/- 10% L-phenylalanine 2.1 g +/- 10%

L-proline 13.3 g +/- 10%

L-serine 3.1 g +/- 10%

L-threonine 1, 8 g +/- 10%

L-Tyrosine 0,35 g +/- 10% L-VaNn 2,4 g +/- 10%

(All weights based on 100 g of protein).

The amino acids used according to the invention are largely split oligopeptides. Ideally, all amino acids are monomeric. For the purposes of the invention, however, it has been found to be sufficient if the peptide bonds are largely split, d. H. Some amino acids may still be present as short-chain oligopeptides. Under short-chain oligopeptides peptides with max. 20, preferably 10 amino acids, more preferably 5 amino acids understood.

The use of individual amino acids instead of long-chain proteins has the advantage that the body can absorb the amino acids directly without first having to cleave the peptide bonds of the proteins. The absorption rate is thus significantly increased. When using proteins, however, a significant part of the body is not absorbed and ultimately excreted. The administration of monomeric amino acids or very short chain oligopeptides is therefore considerably more efficient. The Weight indication "based on 100 g protein" is to be understood that the total amount of amino acids is to be regarded as protein.

This amino acid mixture is optimized in terms of nutritional physiology insofar as it immediately contains all essential building blocks required for the development of endogenous protein in the right proportions. In addition, arginine and lysine are considered growth hormone stimulants that promote fat mobilization and fat burning. Phenylalanine stimulates the production of the hormone cholecystokinin, which controls hunger and appetite. Another advantage of such an amino acid mixture is that it provides in conjunction with the added mineral salts, the iodine and the trace elements contained in KeIp for a balanced nitrogen balance.

The other amino acids used also exert beneficial effects. Glycine also has an appetizing effect. Leucine stimulates protein synthesis (muscle growth) and keeps blood sugar levels stable. Arginine has been shown to be effective against arteriosclerosis (vascular calcification). Methionine is involved in the production of noradrenaline and camitine, which is responsible for the transport of fatty acids through the mitochondrial membrane, where the oxidative degradation of fatty acids occurs. Proline is u. a. a starting material for polyamines, which are essential for cell growth and cell differentiation and develop anabolic action.

Specific embodiment:

The additional foodstuff consists for example of an amino acid mixture consisting of L-alanine 8.7 g

L-arginine 8.15 g

L-aspartic acid 6 g L-glutamic acid 11.1 g L-Glycine 20.6 g L-histidine 0.6 g

L-hydroxylysine 1 g

L-hydroxyproline 11, 4 g of L-isoleucine 1, 6 g

L-leucine 3.3 g

L-lysine 3.9 g

L-methionine 0.6 g

L-phenylalanine 2.1 g L-proline 13.3 g

L-serine 3.1 g

L-threonine 1, 8 g

L-tyrosine 0.35 g

L-valine 2.4 g Further contains the additional food

Calcium phosphate 0.63 g

Magnesium 0.39 g

Potassium 0.18 g

KeIp 0.05 g of which iodine 7.5 mg + traces of tomato extract containing lycopene 0.18 g.

The dietary supplement is fat free, carbohydrate free, purine free and cholesterol free. It is taken as part of a formula diet as a substitute or as a supplement to meals. The dosage is ever according to body weight of the patient between 40 g per day and 80 g per day. The therapy should be accompanied by qualified dieticians and / or medically.

- Claims -

Claims

claims 1. Additional food, in particular for use in diets for sustainable obesity therapy, based on a mixture of 5 amino acids, supplemented by Mineral salts containing 0.5 g to 0.7 g of calcium phosphate, 0.3 g to 0.4 g of magnesium and 0.15 g to 0.25 g of potassium, 0.04 g to 0.06 g KeIp containing 7 mg to 8 mg iodine and trace elements, and lo - 0.15 g to 0.25 g lycopene-containing tomato extract; all weights based on 100 g of protein. 2. Additional food according to claim 1, characterized in that the amino acids are present as monomers. 3. Additional food according to claim 1 or 2, characterized i5 characterized in that the KeIp is obtained from algae of the genus Ascophyllum nodosum. 4. Additional food according to one of claims 1 to 3, in which the amino acid mixture contains: L-Alanine 8.7 g +/- 10% L-arginine 8.15 g +/- 10% L-aspartic acid 6 g +/- 10% L-glutamic acid 11, 1 g +/- 10% L-Glycine 20.6 g +/- 10% L-histidine 0.6 g +/- 10% L-hydroxylysine 1 g +/- 10% L-hydroxyproline 11, 4 g +/- 10% L-isoleucine 1, 6 g +/- 10% L-leucine 3.3 g +/- 10% L-lysine 3.9 g +/- 10% L-methionine 0.6 g +/- 10% L-phenylalanine 2.1 g +/- 10% L-proline 13.3 g +/- 10% L-serine 3.1 g +/- 10% L-threonine 1, 8 g +/- 10% L-Tyrosine 0.35 g +/- 10% L-valine 2.4 g +/- 10% (All weights based on 100 g of protein). - Summary -