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WO1990007353A1 - Regulateur programmable du debit d'un tube flexible et methodes - Google Patents

Regulateur programmable du debit d'un tube flexible et methodes Download PDF

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Publication number
WO1990007353A1
WO1990007353A1 PCT/US1989/000010 US8900010W WO9007353A1 WO 1990007353 A1 WO1990007353 A1 WO 1990007353A1 US 8900010 W US8900010 W US 8900010W WO 9007353 A1 WO9007353 A1 WO 9007353A1
Authority
WO
WIPO (PCT)
Prior art keywords
programmable
tube
flexible
contractible
electrical
Prior art date
Application number
PCT/US1989/000010
Other languages
English (en)
Inventor
David Edward Flinchbaugh
Original Assignee
Medical Inventors Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Inventors Corp. filed Critical Medical Inventors Corp.
Priority to PCT/US1989/000010 priority Critical patent/WO1990007353A1/fr
Publication of WO1990007353A1 publication Critical patent/WO1990007353A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16813—Flow controllers by controlling the degree of opening of the flow line

Definitions

  • This invention relates to hospital, clinical or home-care medical instruments. In one of its embodiments, it is a programmable, pressure- transducer-controlled bladder-drainage cycler. In another of its embodiments, it is a programmable, electrochemical-transducer-controlled medication
  • infusion system that can be made to be implantable or operable from outside the body of a patient. More generally, it is a flow regulator for regulating flow of fluid through a flexible tube for a broad range of industrial and consumer applications.
  • the magnetic bladder cycler provided greater accuracy and reliability in filling the needs of an effective bladder cycler in comparison to prior devices. It was not fully programmable, however. Nor did it permit the control of fluid through a medical tube without flow also
  • This invention allows repeated use of the same control mechanism for different patients. Only the medical tubing needs changing to
  • the control unit can have a long use-life at low cost for a medical tube system without contamination. Further, it is programmable for total control to meet the needs of each patient completely.
  • flow control through a tube decreases contamination by avoiding the many crevices for growth of contamination in and around the components of control mechanisms. Highly significant also, the tube can be replaced easily a minimal costs in comparison to difficult and expensive replacement of present programmable medication infusion mechanisms when they have become inoperable or contaminated.
  • this invention does not require changing as often because it avoids contamination for which changing would be required and its components are longer-lasting and more reliable.
  • Medication can be supplied in either a continuous small stream or in doses as required. Requirements for medication can be determined by electrochemical transducers to assure proper dosage and to prevent overdose hazards. Bladders can be cycled completely without hazardous suction.
  • the medical tubing used can be collapsible to avoid contamination.
  • a major feature of this invention is that in all medical uses, its fluid- flow-control mechanism is most nearly like the natural flow control of fluids by muscular contraction and expansion in a living body. Thus, it is more appropriate and compatible for use by the body.
  • the type of programming to which this invention is suited for most purposes is basically analog as contrasted to digital programming. This approximates body functions as well as most requirements of flow regulation. Smallness in size is critical for implantation of medication infusion systems. This invention can be made much smaller than present control systems because it is simpler in construction and there are fewer parts.
  • Numbers 2,602,448 and 2,860,636 which utilized a siphon in combination with a reservoir to provide cyclic draining of the bladder. Pressure release in these is controlled by raising the height of the device on a bedside tree. It is subject to distortion by shifting and turning of the patient and, therefore, very undependable in addition to being restrictive of the patient.
  • a siphon leg is controlled by merely attaching a catheter to a bedside tree at predetermined adjusted height, which varies the pressure at which the bladder will drain and provides a flutter
  • the flexible tube can be a catheter tube for cycling a bladder or an infusion tube for infusing medication into the blood stream or for infusing medication into the digestive tract.
  • the flow through such tubes can 0 be programmable for control by a pressure transducer, by a chemical transducer, by an electrochemical transducer or by a timer. Either can be made to be overriden manually.
  • the inlet tube utilized is a catheter because the source of fluid is the bladder.
  • the inlet tube is a medication tube because the source of fluid is a medication reservoir.
  • the outlet tube is an excretion discharge conveyance when this invention is employed as a bladder cycler.
  • the outlet tube is a medication infusion tube that is attachable selectively to either the blood system or the digestive tract of a patient.
  • the programmable control principles and mechanisms for both applications are substantially the same except that flow regulation is controlled programmably by a pressure transducer for a bladder cycler and by electrochemical transducers for medication infusion. Both are programmable also for timed valved closing, opening and variable flow regulation. Also, both are provided with manual override.
  • the medication infuser can be miniaturized for implantation into the body of the patient. Partly because it is simple and yet basically free from contamination in operation, it can be made smaller and more reliable than other implantable, programmable medication infusion systems.
  • a controllable-step motor preferably a linear motor
  • a linear motor is utilized to actuate a rod against a flexible tube supported by a base member at the opposite side of the tube in order to prevent or to selectively allow flow of fluid through the tube.
  • a pressure sensor at an inlet side of the rod and base member senses radially outward pressure in the tube and actuates a switch to activate the linear motor as programmed.
  • a chemical transducer, an electrical transducer or both can be employed. Fluid flow of medication through infusion tubes to the blood system or to the digestive tract of patients can be programmed as required.
  • the controllable-step motor can also be rotational with gear drive of a rod which functions as a valve to open and close the tube for selective regulation of flow of fluid.
  • gear drive of a rod which functions as a valve to open and close the tube for selective regulation of flow of fluid.
  • the size of the components can be adjusted to the particular needs.
  • Miniaturization of the invention for such applications as implantable, programmable medication infusion systems can be aided by the use of collapsible tubes to decrease the energy required to operate the linear valve and thereby to decrease the size of the unit.
  • Collapsible tubes also decrease contamination by decreasing fluid remaining within the tubes when not otherwise conveying fluid. This further decreases stagnation conditions in the system.
  • FIG 1 is a cutaway side view of a bladder-cycler embodiment of the invention employing a linear motor in direct actuation of a flexible-tube flow regulator .
  • FIG 2 is a top view of the embodiment illustrated in FIG 1.
  • FIG 3 is a top view of a medication-infusion embodiment of the invention utilizing a linear motor similarly to the FIG 1 illustration.
  • FIG 4 is a schematic side view with a rotational electrically-motorized means in conjunction with an inclined plane.
  • FIG 5 is a schematic side view with a linear electrically-motorized means in conjunction with an inclined plane.
  • FIG 6 is a schematic side view with a linear electrically-motorized means to actuate a plier-like lever and fulcrum.
  • FIG 7 is a flow diagram of a bladder-cycler embodiment of the invention.
  • FIG 8 is a flow diagram of a medication-infusion embodiment of the invention.
  • FIG 9 is a circuit diagram of the invention illustrating circuitry for bladder-cycler, medication-infusion and other applications.
  • a contractible member 1 is actuated selectively in the direction of or in the opposite direction from a base member 2 to regulate flow of fluid through a flexible tube 3.
  • Motion for actuation of the contractible member 1 is transferred through motive member 4 from plunger 5 which can be a conductor in a linear motor having electrical coils 6 in a linear electrical step motor 7.
  • the linear step motor can also be a rotational motor, preferably a rotational step motor, that operates gears. Because either a linear motor or a rotational motor with gears can be employed, an electrical motor of either type is referred to alternatively in this description as an electromotive means.
  • Contractible member 1 and base member 2 can be referred to together as a regulator valve which is opened fully or partially by movement of contractible member 1 selectively in a direction away from base member 2. It is closed by movement of contractible member 1 in a direction towards base member 2 to press opposite sides of a flexible tube 3 together with sufficient force to prevent flow of fluid in through the tube 3.
  • Electrical current is provided to the electrical coils 6 by battery 8 which can be chargeable. Electrical current for charging battery 8 is supplied from battery charge box 9 having electrical plug 10. Low voltage current is transmitted through charger wire 11 to converter 12. The converter
  • the battery charge box 9 is employed to isolate high current of an electrical source from low current in association with a patient or other use condition. This prevents electrical hazards in addition to providing efficient charging of a battery.
  • An optional tube cover 13 is swivelable on hinge bolt 14 to prevent the flexible tube 3 from escaping from between the contractible member 1 and the base member 2 under use conditions.
  • a regulator knob 15 is rotatabie in either direction to select the programmable regime.
  • the program selected is for closing of contractible member 1 and opening it in accordance with pressure in flexible tube 3.
  • the amount of pressure required to open the regulator valve by movement of contractible member 1 away from base member 2 and flexible tube 3 is determined by rotation of pressure knob 16 to require a relatively high pressure at the "HIGH” position at 12 O'clock or a relatively low pressure at the "LOW" position at 6 O'clock markings.
  • the knobs are operated by rotating the arrow on each knob to a desired rotational setting.
  • the regulator valve is closed and set on timed opening rather than pressure-sensor opening by turning regulator knob 15 to "TIMED" position at 6 O'clock on the dial.
  • Time interval for opening the regulator valve by moving contractible member 1 away from base member 2 is determined by rotation of timer knob 17 to hours and portions of hours indicated clockwise on a dial around the outside periphery of timer knob 17.
  • the motive member 4 is held mechanically by brake shoe 18 in whatever position it is moved by the plunger 5. Inward travel of the brake shoe 18 for braking effect is caused by biased pressure of brake spring 19 against brake plunger 20. Brake-releasing outward travel of the brake shoe 18 is caused by electrical charging of electrical brake coil 21.
  • the electrically-motorized means to actuate release of brake shoe 18 can be a linear motor in which electrical current is directed to brake coil 21 from electrical current circuited to electrical coils 6. This causes the 1 brake plunger 21 to travel outwardly to release the brake regardless of which direction the valve plunger 5 is caused to travel. Thus, the valve plunger 5 is released to actuate travel of motive member 4 in either direction but held precisely in programmed positions without expenditure of electrical current
  • brake shoes 18 and brake coils 21 there can be a series of brake shoes 18 and brake coils 21 circumferentially around the outside periphery of plunger 5.
  • the brake shoes and the surface of the plunger can be made appropriate is size and physical nature to maximize effectiveness of this braking system.
  • J multiple brake shoes 18 and the surface of motive member 4 can be appropriately toothed or roughed and staggered for the brake shoes 18 to hold the motive member 4 precisely and reliably with only minimal tension and size of brake spring 19.
  • a pressure-sensing member 22 is biased against flexible tube 3 by pressure-transducer resilient member 23.
  • Increase of o pressure in flexible tube 3 actuates the outside periphery of the flexible tube 3 against the sensing member 22 and causes pressure-transducer resilient member 23 to contract and travel in a direction away from the flexible tube.
  • This travel causes electrically-conductive transducer-plunger points 24 to contact matching stationary pressure transducer points 25.
  • This contact can 5 be programmed to signal opening travel of electromotive means 5.
  • audiovisual warning means 26 which is represented by a circular bell in FIG 2. This is designated by the words "AUDIOVISUAL WARNING" in a FIG 7 flow diagram.
  • the audiovisual warning means 26 can be a bell, a bell and light, or any combination of any type of sound-producing and sight-producing means. Either audio or visual warning means can be used separately without the other within the description and intent of this invention. It is foreseeable that the audiovisual means can be hard-wired to an outside transmitter such that a 5 beeper, a phone, a speaker, lights, radio signals and other selections of warning devices would be actuated within the meaning of audiovisual warning as applied in this invention. 5
  • the brake coil 21 can be caused to release brake shoe 18 against brake resilient member 19 at the same time that the electromotive means 5 is caused to open the contractible member 1 and the audiovisual means 6 is actuated.
  • flow of fluid being regulated by this invention originates from a fluid source 27 and travels towards a fluid destination 28.
  • the fluid source 27 is the bladder of a patient and the fluid destination 28 is a. means for disposing of urine from the bladder.
  • the fluid source 27 is a medication reservoir and the fluid destination 28 is the blood stream or digestive tract of a patient. The main difference is in how it is used.
  • the invention is substantially the same for bladder cycling as for inserting medication into the body of a patient. There are differences only in the types of transducers and the programming utilized. For implantation in bodies of patients, however, the invention can be designed and constructed much smaller and large control knobs would be replaced with minute control members.
  • transducer 29 Differences in relation to transducers would include an optional chemical transducer 29 or an optional electrical transducer 30 in place of or in addition to an optional pressure transducer with part numbers 22 through 25.
  • An electrochemical transducer could be employed to combine the function of chemical transducer 29 and electrical transducer 30.
  • chemical and electrical transducers are not included in this invention. There is a wide variety that can be employed. Typically, chemical transducers would be activated by and measure pH ion concentration for acidity or alkalinity. pH is measured in two basic ways: (1) colorimetrically and (2) electrometrically. For on-line controls such as this invention, standard glass electrodes could be employed electrometrically. Electrical transducers could be variations of the standard Wheatstone
  • a tubing flow-control section 31 can be attachable to flexible tubing at either or both the outlet and inlet sides of the contractible member 1 and base member 2. Such a tubing flow-control section 31 can be selectively collapsible and less resistant to movement of the motive member 4. This would decrease power requirements and thus decrease the size and weight of the invention. It would also decrease accumulation of fluid in the control section 31 and thus also decrease conditions susceptible to buildup of contamination.
  • Resiliency of the flexible tube is important for many of the applications of this invention. Resiliency can be a tradeoff design factor with collapsibility for applications in which flow pressure is low enough for collapsibility to deter flow. Thus, flexibility is intended to include sufficient resiliency of tubes through which flow is regulated with this invention.
  • sealable valves 32 for taking out or putting in fluid separately from flow of fluid through the flexible tube 3.
  • these sealable valves 32 could be used to inject medication, a cultured substance or any modification or mix of the fluid at either the input or the outlet side of the valve.
  • the sealable valves also could be used for sampling the fluid flowing through the control section 31.
  • the sealable valves 32 also could be positions at which additional control transducers could be added.
  • the entire flexible tube 3 can be collapsible for some applications. For some applications, the entire length of the tube 3 would be no longer than illustrated relatively for the control section 31. Both for bladder cycling and for medication infusion, collapsible tubing may be preferable for the entire length of tubing employed.
  • this invention When this invention is utilized for industrial or consumer applications not associated with health-care, medical and hospital uses, it can be constructed in sizes to match any size of tubing or pressure conditions. It can range in size for three-foot-diameter flexible tubing flow-control sections 31 down to flow-control sections less than an eighth of an inch in diameter. It is significant also that fluid conveyances leading to and from this invention can be solid plumbing or other tubing and fluid conveyances when the tubing flow-control section 31 is appropriately flexible, resilient or collapsible.
  • FIG 3 an embodiment of this invention employing chemical and electrical transducers is illustrated from the top with chemical transducer knob 33 and electrical transducer knob 34 in place of the pressure knob 16.
  • This form of the invention is primarily for medication infusion.
  • a timer knob 17 and a regulator knob 15 are shown at opposite ends of the invention for continuity and clarity of description.
  • the invention is also shown proportionately smaller for inference of its smaller construction for
  • I Q implantability in the body of patients It could be made smaller yet by placing all four knobs parallel and at right angles to each other.
  • the knobs can be made much smaller and the mechanisms employed could be miniaturized for implantation. Abbreviations rather than words for chemical, electrical, open, close, high and low are used for decreasing size. j Miniaturization could be aided by appropriate collapsibility and yet resilience of tubing, particularly the tubing flow-control section 31 for the reasons described above.
  • the base member 2 in FIG 3 is shown narrower and shorter than in FIG 2 because it does not include the pressure transducer at that position. Also in
  • FIG 3 the chemical transducer 29 and the electrical transducer 30 are shown for ease of illustration at opposite sides of a fluid destination 28.
  • This is a partially schematic representation of separate transistors in relation to minute fluid disposition conditions in the body of a patient.
  • FIGs 4, 5 and 6 Illustrated schematically in FIGs 4, 5 and 6 are alternative components
  • geared rotational motor 35 preferably a reversible step motor, which rotates a shaft 36 to which a gear wheel 37 is attached.
  • the gear wheel 37 can be "worm” geared for actuation of geared motive member 38 linearly to the axis of the shaft 36.
  • Attached to the geared motive member 38 is an inclined cam 39 which actuates dual cam-follower 40 at right angles to the axis of rotational motor 35 and actuates a rotational-motor motive member 41 with rotational-motor contractible member 42 attached.
  • Opposite sides of flexible tube 3 are caused thereby to be pressed together or allowed to open selectively by fluid pressure within the tube and or by resiliency of the tube for achieving regulation of flow through the flexible tube.
  • Features of the invention not illustrated in relation to the schematic representations are assumed to be similar to those described in relation to other illustrations and related descriptions.
  • geared linear motor 44 preferably a step motor, actuates linearly in both directions a linear-motor shaft 45 to which a direct-drive motive member 46 is attached.
  • linear-motor inclined cam 47 On the direct-drive motive member 46 is linear-motor inclined cam 47 which actuates linear-motor dual cam follower 48.
  • linear-motor contractible member 49 Attached to linear-motor dual cam follower 48 is linear-motor contractible member 49 which is actuated in both directions selectively towards and away from linear-motor base member 50 by opposite-directional linear travel of linear-motor shaft 45.
  • levered linear motor 51 is swivelably attached to inside lever arm 52.
  • Levered linear-motor shaft 53 with attachment member 54 is swivelably attached to outside lever arm 55.
  • Lever arms 52 and 55 are swivelably attached to fulcrum 56.
  • Selectively opposite-directional linear travel of levered linear-motor shaft 53 causes levered linear-motor contractible member 57 to travel selectively towards and away from levered linear-motor base member 58.
  • FIG 7 a flow diagram of a bladder-cycler embodiment of this invention is illustrated with the components indicated by words. Fluid flows from a "BLADDER” to a “VALVE” and then to a “DISPOSITION COUPLING.”
  • a pressure transducer or an override are selected for fluid flow to reach a disposition point at the disposition coupling.
  • Programmed pressure operation of the valve is selected by rotating the regulator knob 15 in FIG 2 to "SENSOR.”
  • Programming can be set for a relatively high or low pressure by rotating the "PRESSURE” knob 16 to "HIGH” and “LOW” settings respectively as illustrated further in FIG 2.
  • the "BRAKE" will maintain the valve in a closed position with contractible member 1 pressing the sides of flexible tube 3 against the base member 2 until the designated pressure is reached.
  • the pressure-sensing member 22 is activated as programmed, there will be an audiovisual warning as designed and programmed, the brake shoe 18 will release the motive member 4 and fluid will be allowed to flow through the flexible tube.
  • the proportion of full open condition of the valve will be determined by the relative rotation of regulator knob 15 towards open and shut respectively.
  • the valve will again close and remain in a closed position by action of brake shoe 18 until a programmed higher pressure is reached in the tubing flow-control section 31.
  • Timed opening is programmed by rotating the regulator knob 18 in FIG 2 to "TIMER" at 6 O'clock. Then the time period between openings is selected by rotating the timer knob 17 to the indicated hours and portions of hours clockwise on the timer dial.
  • the valve will open by travel of contractible member 1 away from the base member 2 and the flexible tube 3.
  • the audiovisual warning will be activated and the brake will be released and reset with the valve in open condition.
  • the brake will be released from open condition, the valve will be shut and the brake will be set again to maintain closed condition without expenditure of electrical energy for continued braking action.
  • FIG 8 a flow diagram of the medication-insertion embodiment in FIG 3 is illustrated with components indicated by descriptive words. Fluid flows from a "MEDICATION RESERVOIR” to a “VALVE” and then to an "INSERTION COUPLING.”
  • alternative programs of either a timer, chemical transducer, electrical transducer or manual override are selected for fluid flow to reach a destination at the insertion coupling.
  • the regulator knob 15 is rotated to where the arrow points to "VALVE.”
  • the knobs are marked with "CH” for the chemical knob and "EL” for the electrical knob. Either or both knobs are programmed by first rotation to a position clockwise or counterclockwise from “H” for high. If the knobs are rotated to any position of rotation between “H” and “L” at the half-circle side marked “C” for closed, the valve will remain open until a relatively high or low chemical or electrical condition being programmed for is reached according to the relative rotation of the arrow between "H” and "L.” When the selective condition is reached, the valve will close.
  • Both knobs must be on the "O" or the "C” side of the dial circles if both electrical and chemical transducers are being programmed. Otherwise, one will cancel the other out because there is only one valve for both. This is consonant with programming regimes for medication infusion because generally the valve should stay either open or closed until either or both chemical and electrical conditions occur. Timed opening or closing of the valve is selected the same for the FIG 3 embodiment as for the FIG 2 embodiment.
  • FIG 8 flow diagram indicates "VARIABLE OPEN-SHUT," "AUDIOVISUAL
  • Variable open and shut are selected as described above by rotation of the arrow on each knob to the relative position of chemical and electrical conditions or of open or closed conditions that are programmed with rotation of the knobs.
  • Actuation of the brake and the audiovisual warning can be automatically simultaneous as programmed the same as described above for FIG 2 in relation bladder cycling.
  • Other uses of this invention for industrial and consumer uses can employ similar programming and control parameters, depending on the particular applications.
  • the battery charge-control unit is separate from the battery to prevent potential electrical hazards. Shock-level electrical current is prevented from reaching a patient when a low-voltage batter is being employed as described above. A converted is employed to convert various levels of current to the particular applications for transducer use and for valve-motor operation. This division of current is indicated functionally in the diagram by "POWER TO LOADS.”
  • Transducer switches are indicated by the circled arrows. At the same time .4 current flows to the valve motor, current flows also to the brake and warning devices as outlined in the flow diagrams, FIGs 7 and 8. Electrical power to operate the brake and warning devices can be in line with flow of current to the valve motor. Electrical current to operate transducers which actuate the brake and warning mechanisms can be in line with the current to the pressure transducer.
  • VALVE TIMER Current flows to a "VALVE TIMER,” to "OTHER TRANSDUCERS” and to an “OVERRIDE” in the same manner as to the pressure transducer.
  • Other transducers can be any type or combination of types of transducers for any application of this device.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La régulation de débit pour tubes flexibles est obtenue en comprimant les côtés opposés d'un tube (3) ou d'une section tubulaire afin de fermer ou d'ouvrir sélectivement par ce moyen le tube de manière programmable à l'aide d'éléments motorisés électriquement. Ceci constitue une forme de vanne ne nécessitant pas de passage de liquide à travers un mécanisme fonctionnant par vanne. Une unité à usage médical hospitalier et pour les soins à domicile permettant de recycler la vessie des malades est présentée, possédant un transducteur (22) chargé d'ouvrir et de fermer la vanne selon la pression programmée ou des intervalles de temps. Un système d'infusion médicamenteuse pouvant s'implanter est obtenu en régularisant le débit de liquide provenant d'un réservoir de médicaments (2) vers le sang ou le système digestif des malades (28) à l'aide de transducteurs électrochimiques appropriés et de réservoirs de médicaments et à l'aide de tubes adéquats. Des applications pour l'industrie et la consommation peuvent être obtenues grâce à un dimensionnement et à des modifications de construction appropriés.
PCT/US1989/000010 1989-01-03 1989-01-03 Regulateur programmable du debit d'un tube flexible et methodes WO1990007353A1 (fr)

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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993010834A1 (fr) * 1991-12-06 1993-06-10 Block Medical, Inc. Appareil de commande pour l'administration de doses multiples
US5445613A (en) * 1993-07-16 1995-08-29 Rocky Mountain Research, Inc. Condition detection system and clamp
WO1996034640A1 (fr) * 1995-05-01 1996-11-07 Infusion Technologies Corporation Systeme a soupape et procede de commande d'une pompe a perfusion
WO2003011375A2 (fr) * 2001-07-26 2003-02-13 Niels Rahe-Meyer Procede et dispositifs d'autodosage et de regulation du dosage d'un medicament liquide
WO2003070314A1 (fr) * 2002-02-22 2003-08-28 Gambro Lundia Ab Procede de controle du fonctionnement d'un element d'interruption d'ecoulement et d'un systeme d'arret d'ecoulement, destine a un circuit de fluide extracorporel
GB2389534A (en) * 2002-06-14 2003-12-17 Margaret Pamela Richardson Improvements in and relating to catheter control
WO2003105942A1 (fr) * 2002-06-14 2003-12-24 Margaret Pamela Richardson Ameliorations apportees ou relatives au controle d'un ecoulement de liquide vers un corps humain ou animal ou hors de celui-ci
EP1383570A2 (fr) * 2001-04-02 2004-01-28 The Hook Research Foundation Regulateur d'ecoulement a travers un tube souple programmable et ses procedes d'utilisation
GB2395128A (en) * 2002-11-14 2004-05-19 Europ Technology For Business Catheter control device
CN100361714C (zh) * 2004-09-13 2008-01-16 毛爱民 可精确控制药液流量的输液泵
RU2534632C1 (ru) * 2013-05-31 2014-12-10 Закрытое акционерное общество Научно-производственный комплекс "КБ ВЗЛЕТ" Управляемый клапан для пережима гибкого трубопровода сепаратора компонентов донорской крови или аутогемотрансфузера
EP1750793A4 (fr) * 2004-05-28 2017-11-15 Carefusion Corporation Regulation de l'ecoulement, detection du gaz et extraction du gaz present dans un systeme d'administration de fluide intraveineux.
WO2021216741A1 (fr) * 2020-04-23 2021-10-28 Covidien Lp Cathéter avec soupapes

Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1610622A (en) * 1926-08-11 1926-12-14 Shaweker Max Blood-transfusion means
US3481334A (en) * 1965-10-07 1969-12-02 Mordechai H Diskin Apparatus for urinary bladder irrigation
US4073292A (en) * 1976-10-29 1978-02-14 William Edelman Control apparatus for the automatic treatment of diabetes
US4111198A (en) * 1977-06-02 1978-09-05 Alvin J. Marx Automated intravenous fluid regulating and administering apparatus
US4230102A (en) * 1977-04-25 1980-10-28 Astra-Sjuco Ab Device for the training of a urine bladder
US4253456A (en) * 1977-08-23 1981-03-03 Dr. Eduard Fresenius Chemisch-Pharmazeutisch Industrie Kg, Apparatebau Kg Artificial endocrinal gland
US4355638A (en) * 1978-12-08 1982-10-26 Josef Hirschmann Infusion apparatus
US4504263A (en) * 1982-12-22 1985-03-12 Valleylab, Inc. Flow rate monitor with optical sensing chamber
US4710166A (en) * 1985-11-08 1987-12-01 Quest Medical, Inc. Automated drug additive infusion system
US4714463A (en) * 1984-11-29 1987-12-22 Minnesota Mining And Manufacturing Company Sequence valve for piggyback IV administration with tube reversal prevention
US4718891A (en) * 1984-05-03 1988-01-12 Henry Ford Hospital Automated hemodialysis control based upon patient blood pressure and heart rate
US4725269A (en) * 1983-05-10 1988-02-16 Critikon, Inc. Crimp valve assembly
US4731069A (en) * 1986-05-01 1988-03-15 Beta Phase, Inc. Intravenous tube and controller therefor
US4808161A (en) * 1986-03-04 1989-02-28 Kamen Dean L Pressure-measurement flow control system
US4820265A (en) * 1986-12-16 1989-04-11 Minnesota Mining And Manufacturing Company Tubing set

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1610622A (en) * 1926-08-11 1926-12-14 Shaweker Max Blood-transfusion means
US3481334A (en) * 1965-10-07 1969-12-02 Mordechai H Diskin Apparatus for urinary bladder irrigation
US4073292A (en) * 1976-10-29 1978-02-14 William Edelman Control apparatus for the automatic treatment of diabetes
US4230102A (en) * 1977-04-25 1980-10-28 Astra-Sjuco Ab Device for the training of a urine bladder
US4111198A (en) * 1977-06-02 1978-09-05 Alvin J. Marx Automated intravenous fluid regulating and administering apparatus
US4253456A (en) * 1977-08-23 1981-03-03 Dr. Eduard Fresenius Chemisch-Pharmazeutisch Industrie Kg, Apparatebau Kg Artificial endocrinal gland
US4355638A (en) * 1978-12-08 1982-10-26 Josef Hirschmann Infusion apparatus
US4504263A (en) * 1982-12-22 1985-03-12 Valleylab, Inc. Flow rate monitor with optical sensing chamber
US4725269A (en) * 1983-05-10 1988-02-16 Critikon, Inc. Crimp valve assembly
US4718891A (en) * 1984-05-03 1988-01-12 Henry Ford Hospital Automated hemodialysis control based upon patient blood pressure and heart rate
US4714463A (en) * 1984-11-29 1987-12-22 Minnesota Mining And Manufacturing Company Sequence valve for piggyback IV administration with tube reversal prevention
US4710166A (en) * 1985-11-08 1987-12-01 Quest Medical, Inc. Automated drug additive infusion system
US4808161A (en) * 1986-03-04 1989-02-28 Kamen Dean L Pressure-measurement flow control system
US4731069A (en) * 1986-05-01 1988-03-15 Beta Phase, Inc. Intravenous tube and controller therefor
US4820265A (en) * 1986-12-16 1989-04-11 Minnesota Mining And Manufacturing Company Tubing set

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993010834A1 (fr) * 1991-12-06 1993-06-10 Block Medical, Inc. Appareil de commande pour l'administration de doses multiples
US5445613A (en) * 1993-07-16 1995-08-29 Rocky Mountain Research, Inc. Condition detection system and clamp
WO1996034640A1 (fr) * 1995-05-01 1996-11-07 Infusion Technologies Corporation Systeme a soupape et procede de commande d'une pompe a perfusion
EP1383570A2 (fr) * 2001-04-02 2004-01-28 The Hook Research Foundation Regulateur d'ecoulement a travers un tube souple programmable et ses procedes d'utilisation
EP1383570A4 (fr) * 2001-04-02 2006-12-27 Hook Res Foundation Regulateur d'ecoulement a travers un tube souple programmable et ses procedes d'utilisation
WO2003011375A2 (fr) * 2001-07-26 2003-02-13 Niels Rahe-Meyer Procede et dispositifs d'autodosage et de regulation du dosage d'un medicament liquide
WO2003011375A3 (fr) * 2001-07-26 2003-08-07 Niels Rahe-Meyer Procede et dispositifs d'autodosage et de regulation du dosage d'un medicament liquide
US8052657B2 (en) 2001-07-26 2011-11-08 Niels Rahe-Meyer Method and devices for self-dosing a liquid medicament and for controlling the dosage of the same
WO2003070314A1 (fr) * 2002-02-22 2003-08-28 Gambro Lundia Ab Procede de controle du fonctionnement d'un element d'interruption d'ecoulement et d'un systeme d'arret d'ecoulement, destine a un circuit de fluide extracorporel
US7393337B2 (en) 2002-02-22 2008-07-01 Gambro Lundia Ab Method of monitoring the operationality of a flow cut-off member and flow arresting system, for an extracorporeal fluid circuit
US7935072B2 (en) 2002-02-22 2011-05-03 Gambro Lundia Ab Method of monitoring the operationality of a flow cut-off member and flow arresting system, for an extracorporeal fluid circuit
WO2003105942A1 (fr) * 2002-06-14 2003-12-24 Margaret Pamela Richardson Ameliorations apportees ou relatives au controle d'un ecoulement de liquide vers un corps humain ou animal ou hors de celui-ci
GB2389534A (en) * 2002-06-14 2003-12-17 Margaret Pamela Richardson Improvements in and relating to catheter control
GB2395128A (en) * 2002-11-14 2004-05-19 Europ Technology For Business Catheter control device
GB2395128B (en) * 2002-11-14 2005-11-16 Europ Technology For Business Urinary drainage catheter
EP1750793A4 (fr) * 2004-05-28 2017-11-15 Carefusion Corporation Regulation de l'ecoulement, detection du gaz et extraction du gaz present dans un systeme d'administration de fluide intraveineux.
CN100361714C (zh) * 2004-09-13 2008-01-16 毛爱民 可精确控制药液流量的输液泵
RU2534632C1 (ru) * 2013-05-31 2014-12-10 Закрытое акционерное общество Научно-производственный комплекс "КБ ВЗЛЕТ" Управляемый клапан для пережима гибкого трубопровода сепаратора компонентов донорской крови или аутогемотрансфузера
WO2021216741A1 (fr) * 2020-04-23 2021-10-28 Covidien Lp Cathéter avec soupapes
US12042607B2 (en) 2020-04-23 2024-07-23 Covidien Lp Catheter with valves

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