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UY38435A - Nuevas urea 6,7-dihidro-4h-pirazol[1,5-a] pirazinas activas contra el virus de la hepatitis b (vhb) - Google Patents

Nuevas urea 6,7-dihidro-4h-pirazol[1,5-a] pirazinas activas contra el virus de la hepatitis b (vhb)

Info

Publication number
UY38435A
UY38435A UY0001038435A UY38435A UY38435A UY 38435 A UY38435 A UY 38435A UY 0001038435 A UY0001038435 A UY 0001038435A UY 38435 A UY38435 A UY 38435A UY 38435 A UY38435 A UY 38435A
Authority
UY
Uruguay
Prior art keywords
hbv
virus
hepatitis
pirazinas
dihidro
Prior art date
Application number
UY0001038435A
Other languages
English (en)
Inventor
Susanne Bonsmann
Alastair Donald
Andreas Urban
Original Assignee
Aicuris Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aicuris Gmbh & Co Kg filed Critical Aicuris Gmbh & Co Kg
Publication of UY38435A publication Critical patent/UY38435A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere, en general, a nuevos agentes antivíricos. Específicamente, la presente invención se refiere a compuestos que pueden inhibir la proteína o proteínas codificada(s) por el virus de la hepatitis B (VHB) o interferir con la función del ciclo de replicación del VHB, a composiciones que comprenden dichos compuestos, a métodos para inhibir la replicación del virus VHB, a métodos para tratar o prevenir la infección por VHB y a procesos e intermedios para la fabricación de los compuestos.
UY0001038435A 2018-11-02 2019-10-31 Nuevas urea 6,7-dihidro-4h-pirazol[1,5-a] pirazinas activas contra el virus de la hepatitis b (vhb) UY38435A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP18000879 2018-11-02

Publications (1)

Publication Number Publication Date
UY38435A true UY38435A (es) 2020-05-29

Family

ID=64362288

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001038435A UY38435A (es) 2018-11-02 2019-10-31 Nuevas urea 6,7-dihidro-4h-pirazol[1,5-a] pirazinas activas contra el virus de la hepatitis b (vhb)

Country Status (15)

Country Link
US (1) US20220009931A1 (es)
EP (1) EP3873907A1 (es)
JP (1) JP2022508042A (es)
KR (1) KR20210098983A (es)
CN (1) CN112969704A (es)
AR (1) AR116948A1 (es)
AU (1) AU2019373678A1 (es)
CA (1) CA3118382A1 (es)
EA (1) EA202191218A1 (es)
IL (1) IL282648A (es)
PH (1) PH12021550976A1 (es)
SG (1) SG11202104114TA (es)
TW (1) TW202031660A (es)
UY (1) UY38435A (es)
WO (1) WO2020089456A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY38434A (es) * 2018-11-02 2020-05-29 Aicuris Gmbh & Co Kg Nuevas 6,7-dihidro-4h-pirazolo[1,5-a]pirazin indol-2-carboxamidas activas contra el virus de la hepatitis b (hbv)
UY38437A (es) * 2018-11-02 2020-05-29 Aicuris Gmbh & Co Kg Nuevas urea 6,7-dihidro-4h-pirazolo[1,5-a]pirazinas activas contra el virus de la hepatitis b (hbv)

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Also Published As

Publication number Publication date
KR20210098983A (ko) 2021-08-11
CN112969704A (zh) 2021-06-15
AR116948A1 (es) 2021-06-30
EA202191218A1 (ru) 2021-07-29
IL282648A (en) 2021-06-30
EP3873907A1 (en) 2021-09-08
WO2020089456A1 (en) 2020-05-07
CA3118382A1 (en) 2020-05-07
TW202031660A (zh) 2020-09-01
PH12021550976A1 (en) 2022-05-02
AU2019373678A1 (en) 2021-05-27
JP2022508042A (ja) 2022-01-19
US20220009931A1 (en) 2022-01-13
SG11202104114TA (en) 2021-05-28

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Legal Events

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Effective date: 20240610