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UY38221A - Inhibidores de proteínas ras con g12c mutantes - Google Patents

Inhibidores de proteínas ras con g12c mutantes

Info

Publication number
UY38221A
UY38221A UY38221A UY38221A UY38221A UY 38221 A UY38221 A UY 38221A UY 38221 A UY38221 A UY 38221A UY 38221 A UY38221 A UY 38221A UY 38221 A UY38221 A UY 38221A
Authority
UY
Uruguay
Prior art keywords
mutants
ras protein
protein inhibitors
refers
compounds
Prior art date
Application number
UY38221A
Other languages
English (en)
Inventor
Grant Kettle Jason
Kaur Bagal Sharanjeet
Richard Robb Graeme
John Eatherton Andrew
Michael Fillery Shaun
Gibson Lamont Scott
David Kemmitt Paul
Woolf Goldberg Frederick
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY38221A publication Critical patent/UY38221A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La memoria descriptiva se refiere a compuestos de Fórmula (I) y sales farmacéuticamente aceptables de estos. La memoria descriptiva también se refiere a procesos e intermedios utilizados para su preparación, a composiciones farmacéuticas que los contienen y a su uso en el tratamiento de trastornos proliferativos celulares.
UY38221A 2018-05-08 2019-05-08 Inhibidores de proteínas ras con g12c mutantes UY38221A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862668321P 2018-05-08 2018-05-08
US201862754814P 2018-11-02 2018-11-02

Publications (1)

Publication Number Publication Date
UY38221A true UY38221A (es) 2019-10-31

Family

ID=66484036

Family Applications (1)

Application Number Title Priority Date Filing Date
UY38221A UY38221A (es) 2018-05-08 2019-05-08 Inhibidores de proteínas ras con g12c mutantes

Country Status (23)

Country Link
US (1) US11407765B2 (es)
EP (1) EP3790884A1 (es)
JP (1) JP7138724B2 (es)
KR (1) KR20210006948A (es)
CN (1) CN112074520A (es)
AU (1) AU2019267008B2 (es)
BR (1) BR112020021467A2 (es)
CA (1) CA3098261A1 (es)
CL (1) CL2020002866A1 (es)
CO (1) CO2020013564A2 (es)
CR (1) CR20200532A (es)
DO (1) DOP2020000201A (es)
EC (1) ECSP20070854A (es)
JO (1) JOP20200281A1 (es)
MA (1) MA52560A (es)
MX (1) MX2020011910A (es)
NI (1) NI202000078A (es)
PE (1) PE20211795A1 (es)
PH (1) PH12020551870A1 (es)
SG (1) SG11202010953QA (es)
TW (1) TW202012415A (es)
UY (1) UY38221A (es)
WO (1) WO2019215203A1 (es)

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