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UY35087A - Derivados de pirrolotriazinona como inhibidores de pi3k - Google Patents

Derivados de pirrolotriazinona como inhibidores de pi3k

Info

Publication number
UY35087A
UY35087A UY0001035087A UY35087A UY35087A UY 35087 A UY35087 A UY 35087A UY 0001035087 A UY0001035087 A UY 0001035087A UY 35087 A UY35087 A UY 35087A UY 35087 A UY35087 A UY 35087A
Authority
UY
Uruguay
Prior art keywords
derivatives
pirrolotriazinona
pi3k inhibitors
formula
inhibitors
Prior art date
Application number
UY0001035087A
Other languages
English (en)
Inventor
Riera Marta Carrascal
Sola Montserrat Erra
Jordi Gracia Ferrer
Original Assignee
Almirall Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Sa filed Critical Almirall Sa
Publication of UY35087A publication Critical patent/UY35087A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Fórmula (I) Se describen nuevos derivados de pirrolotriazinona que tienen la estructura química de fórmula (I); así como un procedimiento para su preparación, composiciones farmacéuticas que los co ntienen y su uso en terapia como inhibidores de F osfoinositido 3-quinasas (PI3Ks).
UY0001035087A 2012-10-16 2013-10-16 Derivados de pirrolotriazinona como inhibidores de pi3k UY35087A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12382398 2012-10-16

Publications (1)

Publication Number Publication Date
UY35087A true UY35087A (es) 2014-05-30

Family

ID=47049113

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001035087A UY35087A (es) 2012-10-16 2013-10-16 Derivados de pirrolotriazinona como inhibidores de pi3k

Country Status (4)

Country Link
AR (1) AR093035A1 (es)
TW (1) TW201422627A (es)
UY (1) UY35087A (es)
WO (1) WO2014060431A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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EP2705029B1 (en) 2011-05-04 2018-10-24 Rhizen Pharmaceuticals S.A. Novel compounds as modulators of protein kinases
JP6291601B2 (ja) 2014-07-04 2018-03-14 ルピン・リミテッド Ｐｉ３ｋ阻害剤としてのキノリジノン誘導体
WO2016054491A1 (en) 2014-10-03 2016-04-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
KR102630013B1 (ko) 2015-08-06 2024-01-25 키메릭스 인크. 항바이러스제로서 유용한 피롤로피리미딘 뉴클레오시드 및 그의 유사체
US10919914B2 (en) 2016-06-08 2021-02-16 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
JP6978507B2 (ja) * 2016-11-18 2021-12-08 システィック・ファイブロシス・ファンデーション Ｃｆｔｒ増強物質としてのピロロピリミジン
US11111264B2 (en) 2017-09-21 2021-09-07 Chimerix, Inc. Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide and uses thereof
CN112645971B (zh) * 2021-01-20 2021-12-24 中国科学院兰州化学物理研究所 一种烷基卤代物直接制备烷基硼酸酯类化合物的方法

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Also Published As

Publication number Publication date
TW201422627A (zh) 2014-06-16
AR093035A1 (es) 2015-05-13
WO2014060431A1 (en) 2014-04-24

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20210617