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UY32315A - Compuestos de piperidina y usos de los mismo-596 - Google Patents

Compuestos de piperidina y usos de los mismo-596

Info

Publication number
UY32315A
UY32315A UY0001032315A UY32315A UY32315A UY 32315 A UY32315 A UY 32315A UY 0001032315 A UY0001032315 A UY 0001032315A UY 32315 A UY32315 A UY 32315A UY 32315 A UY32315 A UY 32315A
Authority
UY
Uruguay
Prior art keywords
same
piperidine compounds
compounds
medicines
processes
Prior art date
Application number
UY0001032315A
Other languages
English (en)
Inventor
Gregory Steven Basarab
Zhou Fei
Hill Pamela
Sherer Brian
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY32315A publication Critical patent/UY32315A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Se describen los compuestos de fórmula (I) y sus sales farmacéuticamente aceptables. También se describen procesos para su preparación, composiciones farmacéuticas que los contienen, su uso como medicamentos y su uso en el tratamiento de infecciones bacterianas.
UY0001032315A 2008-12-12 2009-12-11 Compuestos de piperidina y usos de los mismo-596 UY32315A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12195308P 2008-12-12 2008-12-12

Publications (1)

Publication Number Publication Date
UY32315A true UY32315A (es) 2010-07-30

Family

ID=41818426

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032315A UY32315A (es) 2008-12-12 2009-12-11 Compuestos de piperidina y usos de los mismo-596

Country Status (13)

Country Link
US (2) US8071605B2 (es)
EP (1) EP2376488A1 (es)
JP (1) JP2012511561A (es)
KR (1) KR20110097825A (es)
CN (1) CN102317286A (es)
AR (1) AR074608A1 (es)
AU (1) AU2009326141A1 (es)
BR (1) BRPI0923326A2 (es)
CA (1) CA2745063A1 (es)
MX (1) MX2011005909A (es)
TW (1) TW201026695A (es)
UY (1) UY32315A (es)
WO (1) WO2010067123A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070113233A (ko) * 2005-02-18 2007-11-28 아스트라제네카 아베 항균성 피페리딘 유도체
TW201026694A (en) * 2008-12-12 2010-07-16 Astrazeneca Ab Compound 468
EP2528911B1 (en) 2010-01-28 2017-10-25 President and Fellows of Harvard College Compositions and methods for enhancing proteasome activity
PT2707101T (pt) 2011-05-12 2019-05-30 Proteostasis Therapeutics Inc Reguladores da proteostase
US9849135B2 (en) 2013-01-25 2017-12-26 President And Fellows Of Harvard College USP14 inhibitors for treating or preventing viral infections
WO2015073528A1 (en) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds
WO2015108861A1 (en) 2014-01-14 2015-07-23 Millennium Pharmaceuticals, Inc. Heteroaryls and uses thereof
WO2015108881A1 (en) 2014-01-14 2015-07-23 Millennium Pharmaceuticals, Inc. Heteroaryls and uses thereof
ES2820923T3 (es) * 2015-05-13 2021-04-22 Alivecor Inc Monitorización de discordancias
CN105067814A (zh) * 2015-07-24 2015-11-18 中国科学院成都生物研究所 解旋酶水解atp活性测定方法
US10399968B2 (en) 2015-09-30 2019-09-03 Daiichi Sankyo Company, Limited Hydroxyalkyl thiadiazole derivatives
US11857352B2 (en) 2016-09-06 2024-01-02 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
JP2020511457A (ja) 2017-03-14 2020-04-16 第一三共株式会社 ヒドロキシアルキルチアジアゾール誘導体のｎ−ホスホノキシメチルプロドラッグ
EP3604281A4 (en) 2017-03-24 2020-08-19 Taisho Pharmaceutical Co., Ltd. 2(1h)-quinolinone derivative
WO2020048949A1 (en) 2018-09-03 2020-03-12 Univerza V Ljubljani New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria
WO2022129327A1 (en) 2020-12-17 2022-06-23 Univerza V Ljubljani New n-phenylpyrrolamide inhibitors of dna gyrase and topoisomerase iv with antibacterial activity
CN115466246B (zh) * 2021-06-11 2024-02-06 中国医学科学院药物研究所 吡咯酰哌啶胺类化合物及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2735475B1 (fr) 1995-06-13 1997-07-11 Synthelabo Derives de n-((1,4-diazabicyclo(2.2.2)oct-2-yl)methyl) benzamide, leur preparation et leur application en therapeutique
TW538046B (en) 1998-01-08 2003-06-21 Hoechst Marion Roussel Inc Aromatic amides having antiobiotic activities and the preparation processes, intermediates and pharmaceutical composition thereof
DK1251848T3 (da) 2000-01-18 2004-10-18 Vertex Pharma Gyraseinhibitorer og anvendelse deraf
EP1341769B1 (en) 2000-12-15 2007-10-17 Vertex Pharmaceuticals Incorporated Bacterial gyrase inhibitors and uses thereof
PL369856A1 (en) 2001-12-21 2005-05-02 Anormed Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
TW200526626A (en) 2003-09-13 2005-08-16 Astrazeneca Ab Chemical compounds
KR20070113233A (ko) 2005-02-18 2007-11-28 아스트라제네카 아베 항균성 피페리딘 유도체
JP2008530192A (ja) 2005-02-18 2008-08-07 アストラゼネカ アクチボラグ Ｄｎａジャイレース及びトポイソメラーゼの阻害剤としてのピロール誘導体
US20080161306A1 (en) 2005-02-18 2008-07-03 Brian Sherer Pyrrole Derivatives as Dna Gyrase and Topoisomerase Inhibitors
JP2008531673A (ja) 2005-03-04 2008-08-14 アストラゼネカ アクチボラグ 抗菌活性をもつアゼチジン及びピロールの三環式誘導体
WO2006092599A2 (en) 2005-03-04 2006-09-08 Astrazeneca Ab Pyrrole derivatives as dna gyrase and topoisomerase inhibitors
TW200819437A (en) 2006-08-17 2008-05-01 Astrazeneca Ab Chemical compounds
TW200906412A (en) 2007-06-12 2009-02-16 Astrazeneca Ab Piperidine compounds and uses thereof

Also Published As

Publication number Publication date
AR074608A1 (es) 2011-01-26
MX2011005909A (es) 2011-06-20
US20120028979A1 (en) 2012-02-02
US20100173909A1 (en) 2010-07-08
EP2376488A1 (en) 2011-10-19
WO2010067123A1 (en) 2010-06-17
US8071605B2 (en) 2011-12-06
AU2009326141A1 (en) 2011-06-30
CN102317286A (zh) 2012-01-11
KR20110097825A (ko) 2011-08-31
CA2745063A1 (en) 2010-06-17
BRPI0923326A2 (pt) 2017-07-11
TW201026695A (en) 2010-07-16
JP2012511561A (ja) 2012-05-24

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20181219