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UY31714A - Preparación selectiva de pirimidinas sustituidas - Google Patents

Preparación selectiva de pirimidinas sustituidas

Info

Publication number
UY31714A
UY31714A UY0001031714A UY31714A UY31714A UY 31714 A UY31714 A UY 31714A UY 0001031714 A UY0001031714 A UY 0001031714A UY 31714 A UY31714 A UY 31714A UY 31714 A UY31714 A UY 31714A
Authority
UY
Uruguay
Prior art keywords
pyrimidins
substituted
selective preparation
selective
preparation
Prior art date
Application number
UY0001031714A
Other languages
English (en)
Inventor
Duran Adil
Goepper Stefan
Konrad Michael
Halmer Joerg
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of UY31714A publication Critical patent/UY31714A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La presente invención se refiere a un método para hacer intermedios de pirimidina de fórmula (III) en los que X1, X2, R1 y R2 tienen los significados como se definen en este documento.
UY0001031714A 2008-03-20 2009-03-16 Preparación selectiva de pirimidinas sustituidas UY31714A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08153122 2008-03-20

Publications (1)

Publication Number Publication Date
UY31714A true UY31714A (es) 2009-11-10

Family

ID=40933625

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001031714A UY31714A (es) 2008-03-20 2009-03-16 Preparación selectiva de pirimidinas sustituidas

Country Status (9)

Country Link
US (2) US8334383B2 (es)
EP (1) EP2268622A1 (es)
JP (2) JP5330497B2 (es)
AR (1) AR071005A1 (es)
CA (1) CA2718892A1 (es)
PE (1) PE20091676A1 (es)
TW (1) TW200944509A (es)
UY (1) UY31714A (es)
WO (1) WO2009115587A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY31714A (es) * 2008-03-20 2009-11-10 Boehringer Ingelheim Int Preparación selectiva de pirimidinas sustituidas
EP2268621A1 (en) 2008-03-20 2011-01-05 Boehringer Ingelheim International GmbH Regioselective preparation of substituted pyrimidines
WO2011018517A1 (en) * 2009-08-14 2011-02-17 Boehringer Ingelheim International Gmbh Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives
US8933227B2 (en) * 2009-08-14 2015-01-13 Boehringer Ingelheim International Gmbh Selective synthesis of functionalized pyrimidines
JP6391988B2 (ja) * 2014-05-21 2018-09-19 東ソー・ファインケム株式会社 ５−（トリフルオロメチル）ピリミジン誘導体の製造方法及び新規５−（トリフルオロメチル）ピリミジン誘導体
CN108440499A (zh) * 2018-03-22 2018-08-24 盐城师范学院 一种色瑞替尼及其关键中间体的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6262A (ja) 1986-03-05 1987-01-06 Ishihara Sangyo Kaisha Ltd ベンゾイルウレア系化合物の製造方法
WO2005023780A1 (en) * 2003-09-05 2005-03-17 Pfizer Products Inc. Selective synthesis of cf3-substituted pyrimidines
JP2008540391A (ja) * 2005-05-05 2008-11-20 アストラゼネカ アクチボラグ ピラゾリルアミノ置換ピリミジン、および癌の処置におけるそれらの使用
BRPI0620324A2 (pt) * 2005-12-21 2011-11-08 Pfizer Prod Inc derivados de pirimidina, composição farmaceutica e uso dos mesmos
EP2007754A1 (en) * 2006-04-10 2008-12-31 Boehringer Ingelheim International GmbH 2, 4-diaminopyrimidine derivatives and their use for the treatment of cancer
PE20120006A1 (es) * 2006-05-15 2012-02-02 Boehringer Ingelheim Int Compuestos derivados de pirimidina como inhibidores de la quinasa aurora
EP2089384B1 (en) 2006-12-13 2015-08-05 F. Hoffmann-La Roche AG 2-(piperidin-4-yl)-4-phenoxy-or phenylamino-pyrimidine derivatives as non-nucleoside reverse transcriptase inhibitors
DK2146779T3 (en) * 2007-04-18 2016-11-28 Pfizer Prod Inc Sulfonylamid derivatives to treat abnormal cell growth.
UY31714A (es) * 2008-03-20 2009-11-10 Boehringer Ingelheim Int Preparación selectiva de pirimidinas sustituidas
EP2268621A1 (en) * 2008-03-20 2011-01-05 Boehringer Ingelheim International GmbH Regioselective preparation of substituted pyrimidines
WO2011018517A1 (en) 2009-08-14 2011-02-17 Boehringer Ingelheim International Gmbh Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives
US8933227B2 (en) 2009-08-14 2015-01-13 Boehringer Ingelheim International Gmbh Selective synthesis of functionalized pyrimidines

Also Published As

Publication number Publication date
JP2013237687A (ja) 2013-11-28
US20110077403A1 (en) 2011-03-31
JP2011515375A (ja) 2011-05-19
WO2009115587A1 (en) 2009-09-24
US20130079519A1 (en) 2013-03-28
PE20091676A1 (es) 2009-11-12
AR071005A1 (es) 2010-05-19
EP2268622A1 (en) 2011-01-05
US8334383B2 (en) 2012-12-18
CA2718892A1 (en) 2009-09-24
JP5330497B2 (ja) 2013-10-30
TW200944509A (en) 2009-11-01

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20181017