UY29128A1 - Proteinas derivadas de inmunoglobulina específica de il-23p40, composiciones, epitopes, métodos y usos - Google Patents
Proteinas derivadas de inmunoglobulina específica de il-23p40, composiciones, epitopes, métodos y usosInfo
- Publication number
- UY29128A1 UY29128A1 UY29128A UY29128A UY29128A1 UY 29128 A1 UY29128 A1 UY 29128A1 UY 29128 A UY29128 A UY 29128A UY 29128 A UY29128 A UY 29128A UY 29128 A1 UY29128 A1 UY 29128A1
- Authority
- UY
- Uruguay
- Prior art keywords
- methods
- compositions
- derived
- epithopes
- proteins derived
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Una proteína derivada de Ig humana, específica de anti-IL-23, ácidos nucleicos aislados, que codifican por lo menos una proteina derivada de Ig anti-IL-23, vectores, células huésped, plantas o animales transgénicos, y los métodos para preparar y usar los mismos, que son útiles como composiciones, métodos y dispositivos terapéuticos y de diagnóstico. La proteína derivada de Ig anti-IL-23 se une preferiblemente a uno o más de los epitopes Seg1, Seg2, y Seg3 de la subunidad p40 de IL-23.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61286604P | 2004-09-24 | 2004-09-24 | |
US61683204P | 2004-10-07 | 2004-10-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY29128A1 true UY29128A1 (es) | 2005-11-30 |
Family
ID=36119430
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY29128A UY29128A1 (es) | 2004-09-24 | 2005-09-23 | Proteinas derivadas de inmunoglobulina específica de il-23p40, composiciones, epitopes, métodos y usos |
Country Status (7)
Country | Link |
---|---|
US (2) | US7252971B2 (es) |
AR (1) | AR051444A1 (es) |
MY (1) | MY141215A (es) |
PE (1) | PE20060694A1 (es) |
TW (1) | TWI370136B (es) |
UY (1) | UY29128A1 (es) |
WO (1) | WO2006036745A2 (es) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6706264B1 (en) | 1994-03-14 | 2004-03-16 | Genetics Institute, Llc | Use of IL-12 antagonists in the treatment of conditions promoted by an increase in levels of IFN-y |
DK1576011T3 (da) | 2002-10-30 | 2009-11-30 | Genentech Inc | Inhibering af IL-17 produktion |
WO2008109782A2 (en) * | 2007-03-06 | 2008-09-12 | Cedars-Sinai Medical Center | Diagnosis of inflammatory bowel disease in children |
CA3204588A1 (en) * | 2004-12-08 | 2006-06-15 | Cedars-Sinai Medical Center | Methods for diagnosis and treatment of crohn's disease |
SI2452694T1 (sl) | 2005-06-30 | 2019-05-31 | Janssen Biotech, Inc. | Protitelesa proti-IL-23, sestavki in postopki uporabe |
EP2354160A1 (en) | 2005-08-31 | 2011-08-10 | Schering Corporation | Engineered anti-IL-23-antibodies |
PL1933869T3 (pl) | 2005-09-01 | 2010-06-30 | Merck Sharp & Dohme | Zastosowanie antagonistów IL-23 i IL-17 do leczenia autoimmunologicznej zapalnej choroby oczu |
US10716749B2 (en) * | 2005-11-03 | 2020-07-21 | Palo Alto Investors | Methods and compositions for treating a renal disease condition in a subject |
MX2008008621A (es) | 2005-12-29 | 2008-11-27 | Centocor Inc | Anticuerpos anti-il-23 humanos, composiciones, metodos y usos. |
JP2009540018A (ja) * | 2006-06-13 | 2009-11-19 | ザイモジェネティクス, インコーポレイテッド | Il−17およびil−23アンタゴニストならびにその使用方法 |
TWI426918B (zh) * | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
US20100021917A1 (en) * | 2007-02-14 | 2010-01-28 | Cedars-Sinai Medical Center | Methods of using genes and genetic variants to predict or diagnose inflammatory bowel disease |
US20100190162A1 (en) * | 2007-02-26 | 2010-07-29 | Cedars-Sinai Medical Center | Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease |
WO2008106131A2 (en) | 2007-02-28 | 2008-09-04 | Schering Corporation | Combination therapy for treatment of immune disorders |
WO2010039931A2 (en) * | 2008-10-01 | 2010-04-08 | Cedars-Sinai Medical Center | Methods of using il17rd and il23-il17 pathway genes to diagnose crohn's disease |
WO2008137762A2 (en) * | 2007-05-04 | 2008-11-13 | Cedars-Sinai Medical Center | Methods of diagnosis and treatment of crohn's disease |
US20100055700A1 (en) * | 2007-02-28 | 2010-03-04 | Cedars-Sinai Medical Center | Role of il-12, il-23 and il-17 receptors in inflammatory bowel disease |
US8486640B2 (en) | 2007-03-21 | 2013-07-16 | Cedars-Sinai Medical Center | Ileal pouch-anal anastomosis (IPAA) factors in the treatment of inflammatory bowel disease |
US20100184050A1 (en) * | 2007-04-26 | 2010-07-22 | Cedars-Sinai Medical Center | Diagnosis and treatment of inflammatory bowel disease in the puerto rican population |
US9305137B1 (en) | 2007-05-18 | 2016-04-05 | Cedars-Sinai Medical Center | Methods of identifying the genetic basis of a disease by a combinatorial genomics approach, biological pathway approach, and sequential approach |
WO2008143892A1 (en) * | 2007-05-18 | 2008-11-27 | New York University | Method of treating tuberculosis with interferons |
US9421356B2 (en) * | 2007-08-28 | 2016-08-23 | Teikoku Pharma Usa, Inc. | Transdermal methods and systems for the delivery of corticosteroid compounds |
WO2009059277A1 (en) * | 2007-11-02 | 2009-05-07 | University Of South Florida | Synergistic modulation of microglial activation by nicotine and thc |
SG190626A1 (en) | 2008-05-05 | 2013-06-28 | Novimmune Sa | Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof |
MX2010012442A (es) * | 2008-05-13 | 2011-10-11 | Astrazeneca Ab | Sal de fumarato de 4-(3-cloro-2-fluoroanilino)-7-metoxi-6-{[1-(n-m etilcarbamoilmetil) piperidin-4-il]oxi}quinazolina. |
US20110130457A1 (en) * | 2008-08-06 | 2011-06-02 | University Of Louisville Research Foundation, Inc. | Wax-Based Emulsion for the Treatment of Dry Eye Conditions |
WO2010017598A1 (en) * | 2008-08-14 | 2010-02-18 | Arana Therapeutics Limited | Anti-il-12/il-23 antibodies |
US20110189685A1 (en) * | 2008-10-22 | 2011-08-04 | Cedars-Sinai Medical Center | Methods of using jak3 genetic variants to diagnose and predict crohn's disease |
US7635707B1 (en) | 2008-11-10 | 2009-12-22 | Intermune, Inc. | Pirfenidone treatment for patients with atypical liver function |
US20110229471A1 (en) * | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
CN102256943A (zh) * | 2008-12-18 | 2011-11-23 | 诺瓦提斯公司 | 1-(4-{1-[(e)-4-环己基-3-三氟甲基-苄氧基亚氨基]-乙基}-2-乙基-苄基)-氮杂环丁烷-3-甲酸的半富马酸盐 |
US9580752B2 (en) | 2008-12-24 | 2017-02-28 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy |
CN102458437B (zh) | 2009-05-05 | 2015-06-10 | 诺维莫尼公司 | 抗il-17f抗体及其使用方法 |
CN102421420A (zh) * | 2009-05-13 | 2012-04-18 | 蛋白传输解决方案有限责任公司 | 用于跨膜递送的药物系统 |
US20110086806A1 (en) * | 2009-10-09 | 2011-04-14 | Anaphore, Inc. | Polypeptides that Bind IL-23R |
JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
GB201013975D0 (en) | 2010-08-20 | 2010-10-06 | Imp Innovations Ltd | Method of treating desease |
EP2542982A4 (en) * | 2010-03-05 | 2016-10-26 | Infrared5 Inc | SYSTEM AND METHOD FOR TWO-WAY COMMUNICATION AND FOR CONTROLLING CONTENTS IN A WEB BROWSER |
US20110311527A1 (en) | 2010-06-16 | 2011-12-22 | Allergan, Inc. | IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS |
JP5972871B2 (ja) * | 2010-07-20 | 2016-08-17 | テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド | 抗il−23ヘテロ二量体特異的抗体 |
CN103649336A (zh) | 2011-05-10 | 2014-03-19 | 雀巢产品技术援助有限公司 | 用于个体化治疗管理的疾病活动性表征方法 |
WO2014113068A1 (en) * | 2013-01-18 | 2014-07-24 | Loma Linda University | Compositions and methods for diagnosing and treating sepsis |
JP6671276B2 (ja) | 2013-03-27 | 2020-03-25 | セダーズ−シナイ メディカル センター | Tl1a機能および関連するシグナル経路の抑制による線維症および炎症の緩和および回復 |
EP4105236A1 (en) | 2013-07-19 | 2022-12-21 | Cedars-Sinai Medical Center | Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease |
KR20240095481A (ko) | 2016-03-17 | 2024-06-25 | 세다르스-신나이 메디칼 센터 | Rnaset2를 통한 염증성 장 질환의 진단 방법 |
US20180164221A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
WO2018112232A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device |
KR20200009095A (ko) | 2017-05-31 | 2020-01-29 | 프로메테우스 바이오사이언시즈, 인크. | 크론병 환자에서 점막 치유를 평가하는 방법 |
KR20200129125A (ko) | 2018-03-05 | 2020-11-17 | 얀센 바이오테크 인코포레이티드 | 항-il23 특이적 항체로 크론병을 치료하는 방법 |
US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
WO2019246271A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor |
EP3883635A1 (en) | 2018-11-19 | 2021-09-29 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
MA55149A (fr) | 2018-11-20 | 2021-09-29 | Janssen Biotech Inc | Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique anti-il-23 |
CA3138241A1 (en) | 2019-05-23 | 2020-11-26 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
WO2021119482A1 (en) | 2019-12-13 | 2021-06-17 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
US6060284A (en) * | 1997-07-25 | 2000-05-09 | Schering Corporation | DNA encoding interleukin-B30 |
PE20000183A1 (es) | 1997-07-25 | 2000-03-11 | Schering Corp | Citoquinas de mamiferos y reactivos relacionados |
WO1999040195A1 (en) | 1998-02-06 | 1999-08-12 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
AU3170199A (en) * | 1998-04-14 | 1999-11-08 | Chugai Research Institute For Molecular Medicine, Inc. | Novel cytokine-like protein |
EP1112286A1 (en) | 1998-08-14 | 2001-07-04 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
DE60041393D1 (de) | 1999-03-11 | 2009-03-05 | Schering Corp | Cytokine aus säugetieren, verwandte reagenzien und verfahren |
US6800460B1 (en) * | 1999-03-11 | 2004-10-05 | Schering Corporation | Mammalian cytokine complexes |
WO2000070049A2 (en) | 1999-05-19 | 2000-11-23 | Incyte Genomics, Inc. | Extracellular signaling molecules |
JP4505166B2 (ja) | 1999-09-09 | 2010-07-21 | シェーリング コーポレイション | 哺乳動物インターロイキン−12p40およびインターロイキンb30、その組成物、抗体、薬学的組成物における使用 |
US7090847B1 (en) * | 1999-09-09 | 2006-08-15 | Schering Corporation | Mammalian cytokines; related reagents and methods |
US7422743B2 (en) * | 2000-05-10 | 2008-09-09 | Schering Corporation | Mammalian receptor protein DCRS5;methods of treatment |
MXPA02011081A (es) * | 2000-05-10 | 2003-03-10 | Schering Corp | Proteinas de subunidad de receptor de citocina de mamifero, reactivos y metodos relacionados. |
CA2489722A1 (en) * | 2002-07-17 | 2004-01-22 | William Howard Roark | Combination of an allosteric alkyne inhibitor of matrix metalloproteinase-13 with celecoxib or valdecoxib |
DK1576011T3 (da) | 2002-10-30 | 2009-11-30 | Genentech Inc | Inhibering af IL-17 produktion |
CA2506672C (en) | 2002-12-23 | 2012-04-17 | Schering Corporation | Il-23 for treating cutaneous wounds |
WO2004071517A2 (en) | 2003-02-06 | 2004-08-26 | Schering Corporation | Uses of il-23 related reagents |
BRPI0408247A (pt) | 2003-03-10 | 2006-03-01 | Schering Corp | usos de antagonistas e agonistas de il-23 e reagentes relacionados |
JP2007535930A (ja) * | 2004-05-03 | 2007-12-13 | シェーリング コーポレイション | 皮膚の炎症を予測するためのil−17発現の使用;処置方法 |
-
2005
- 2005-09-20 AR ARP050103931A patent/AR051444A1/es unknown
- 2005-09-22 PE PE2005001099A patent/PE20060694A1/es not_active Application Discontinuation
- 2005-09-22 MY MYPI20054459A patent/MY141215A/en unknown
- 2005-09-23 US US11/234,011 patent/US7252971B2/en active Active
- 2005-09-23 UY UY29128A patent/UY29128A1/es unknown
- 2005-09-23 TW TW094132925A patent/TWI370136B/zh not_active IP Right Cessation
- 2005-09-23 WO PCT/US2005/034000 patent/WO2006036745A2/en active Application Filing
-
2007
- 2007-06-26 US US11/768,582 patent/US7807471B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20060067936A1 (en) | 2006-03-30 |
US7807471B2 (en) | 2010-10-05 |
WO2006036745A3 (en) | 2006-12-28 |
PE20060694A1 (es) | 2006-09-01 |
US20080038831A1 (en) | 2008-02-14 |
MY141215A (en) | 2010-03-31 |
AR051444A1 (es) | 2007-01-17 |
TWI370136B (en) | 2012-08-11 |
WO2006036745A2 (en) | 2006-04-06 |
TW200626173A (en) | 2006-08-01 |
US7252971B2 (en) | 2007-08-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UY29128A1 (es) | Proteinas derivadas de inmunoglobulina específica de il-23p40, composiciones, epitopes, métodos y usos | |
CR9265A (es) | Anticuerpos anti-il-12, y epitopes, composiciones, metodos de obtencion y usos de los mismos | |
EA200601603A1 (ru) | Миметические антитела glp-1 человека, композиции, способы и применения | |
EA201070479A1 (ru) | Человеческие антиамилоидные антитела, композиции, способы и их применение | |
HN2006016512A (es) | Anticuerpos anti-il-6, composiciones, metodos y usos | |
EA200501524A1 (ru) | Антитела против амилоида, композиции, способы и применения | |
BRPI0921665A2 (pt) | humanizado anti-il-6 anticorpos | |
EA200702532A1 (ru) | Антитела против мср-1, композиции, способы и применения | |
CY1121252T1 (el) | Anti-il-23 αντισωματα, συνθεσεις, μεθοδοι και χρησεις | |
EA202091710A1 (ru) | Антитела против cd73 и способы их применения | |
EA200970131A1 (ru) | Миметические антитела для glp-1 человека, композиции, способы и применения | |
AR073088A1 (es) | Anticuerpos anti-il-13 obtenidos mediante ingenieria composiciones metodos y usos | |
AR069681A1 (es) | Moleculas de union al receptor ox40 humano | |
AR079114A1 (es) | Proteinas de enlace de antigenos anti-orai1 y usos de las mismas | |
ECSP088591A (es) | Anticuerpos anti-il-23 humanos, composiciones, metodos y usos | |
WO2006085961A3 (en) | Anti-mcp-1 antibodies, compositions, methods and uses | |
WO2006124451A3 (en) | Anti-il-13 antibodies, compositions, methods and uses | |
AR042968A1 (es) | Anticuerpos de virus anti-dengue composiciones metodos y usos | |
UY29509A1 (es) | Anticuerpos anti-il-6, composiciones, métodos y usos | |
UY29552A1 (es) | Anticuerpos anti-mcp-1, composiciones, métodos y usos | |
UY33043A (es) | Proteinas de enlace de antigenos anti-orai 1 y usos de las mismas |