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AR069681A1 - Moleculas de union al receptor ox40 humano - Google Patents

Moleculas de union al receptor ox40 humano

Info

Publication number
AR069681A1
AR069681A1 ARP080105418A ARP080105418A AR069681A1 AR 069681 A1 AR069681 A1 AR 069681A1 AR P080105418 A ARP080105418 A AR P080105418A AR P080105418 A ARP080105418 A AR P080105418A AR 069681 A1 AR069681 A1 AR 069681A1
Authority
AR
Argentina
Prior art keywords
molecules
binding molecules
methods
human receiver
nucleic acid
Prior art date
Application number
ARP080105418A
Other languages
English (en)
Original Assignee
Medarex Inc
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40552119&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR069681(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medarex Inc, Pfizer filed Critical Medarex Inc
Publication of AR069681A1 publication Critical patent/AR069681A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Anticuerpos aislados que se unen al OX40R humano, las moléculas de ácido nucleico que codifican la secuencia de aminoácidos de las moléculas de union, los vectores que comprenden las moléculas de ácido nucleicos, las células huésped que contienen los vectores, los métodos de obtencion de las moléculas de union, las composiciones farmacéuticas que contienen las moléculas de union, y los métodos de uso de las moléculas de union o composiciones para inhibir el crecimiento de células tumorales.
ARP080105418A 2007-12-14 2008-12-12 Moleculas de union al receptor ox40 humano AR069681A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1394707P 2007-12-14 2007-12-14

Publications (1)

Publication Number Publication Date
AR069681A1 true AR069681A1 (es) 2010-02-10

Family

ID=40552119

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP080105418A AR069681A1 (es) 2007-12-14 2008-12-12 Moleculas de union al receptor ox40 humano
ARP170102289A AR109355A2 (es) 2007-12-14 2017-08-16 Moléculas de unión al receptor ox40 humano

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP170102289A AR109355A2 (es) 2007-12-14 2017-08-16 Moléculas de unión al receptor ox40 humano

Country Status (29)

Country Link
US (7) US7960515B2 (es)
EP (4) EP3239178A1 (es)
JP (4) JP5761997B2 (es)
KR (2) KR20150061041A (es)
CN (1) CN101918447B (es)
AR (2) AR069681A1 (es)
AU (1) AU2008338591B8 (es)
BR (1) BRPI0820875B1 (es)
CA (2) CA2949772A1 (es)
CL (1) CL2008003706A1 (es)
CO (1) CO6280541A2 (es)
DK (3) DK2594590T3 (es)
ES (3) ES2425269T3 (es)
HR (1) HRP20141188T8 (es)
HU (1) HUE032735T2 (es)
IL (3) IL206297A (es)
MX (1) MX2010006466A (es)
PA (1) PA8807601A1 (es)
PE (1) PE20091269A1 (es)
PH (1) PH12015500806A1 (es)
PL (2) PL2594590T3 (es)
PT (3) PT2851374T (es)
RU (1) RU2010129045A (es)
SG (2) SG186656A1 (es)
SI (3) SI2851374T1 (es)
TW (1) TW200932268A (es)
UY (1) UY31533A1 (es)
WO (1) WO2009079335A1 (es)
ZA (1) ZA201003579B (es)

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