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US3720760A - Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples - Google Patents

Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples Download PDF

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Publication number
US3720760A
US3720760A US00758131A US75813168A US3720760A US 3720760 A US3720760 A US 3720760A US 00758131 A US00758131 A US 00758131A US 75813168 A US75813168 A US 75813168A US 3720760 A US3720760 A US 3720760A
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US
United States
Prior art keywords
reagin
immunoglobulins
determining
directed against
against certain
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Expired - Lifetime
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US00758131A
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Leif E Wide
Hans H Bennich
Stig G O Johansson
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Pfizer Health AB
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Pharmacia AB
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Priority to US00758131A priority Critical patent/US3720760A/en
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Assigned to PHARMACIA, INC., A CORP. OF N.J. reassignment PHARMACIA, INC., A CORP. OF N.J. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: PHARMACIA AB, A CORP. OF SWEDEN
Assigned to PHARMACIA AB. reassignment PHARMACIA AB. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: PHARMACIA, INC.
Publication of US3720760B1 publication Critical patent/US3720760B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

AN IN VITRO METHOD FOR ANALYZING A BODY FLUID FOR REAGIN-IMMUNOGLOBULINS THEREIN THAT ARE REACTIVE WITH ALLERGENS WHICH COMPRISES CONTACTING A SAMPLE OF BODY FLUID WITH A WATER-INSOLUBLE POLYMER TO WHICH IS ATTACHED AT LEAST ONE TEST ALLERGEN FOR A LONG ENOUGH TIME TO ALLOW REACTION THEREBETWEEN AND THEN CONTACTING WITH EITHER LABELLED ANTIBODIES THAT ARE REACTIVE WITH THE REAGIN IMMUNOGLOBULINS OR WITH ANTIBODIES AGAINST REAGIN-IG AND REAGIN-IG LABELLED WITH A RADIATION EMITTING ATOM OR GROUP, SEPARATING INTO A LIQUID PHASE AND A SOLID PHASE, AND MEASURING THE RADIATION EMITTED FROM AT LEAST ONE OF THE TWO SEPARATED PHASES.
US00758131A 1968-09-06 1968-09-06 Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples Expired - Lifetime US3720760A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US00758131A US3720760A (en) 1968-09-06 1968-09-06 Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00758131A US3720760A (en) 1968-09-06 1968-09-06 Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples

Publications (2)

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US3720760A true US3720760A (en) 1973-03-13
US3720760B1 US3720760B1 (en) 1984-02-07

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