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UA96766C2 - Гетероциклические соединения, пригодные для лечения болезней, которые имеют отношение к повышенному уровню липидов - Google Patents

Гетероциклические соединения, пригодные для лечения болезней, которые имеют отношение к повышенному уровню липидов

Info

Publication number
UA96766C2
UA96766C2 UAA200900859A UAA200900859A UA96766C2 UA 96766 C2 UA96766 C2 UA 96766C2 UA A200900859 A UAA200900859 A UA A200900859A UA A200900859 A UAA200900859 A UA A200900859A UA 96766 C2 UA96766 C2 UA 96766C2
Authority
UA
Ukraine
Prior art keywords
treatment
heterocyclic compounds
diseases related
compounds suitable
lipid level
Prior art date
Application number
UAA200900859A
Other languages
English (en)
Ukrainian (uk)
Inventor
Нетали Дейлз
Джулия Фонейрив
Цзянмин Фу
Раджендер Камбодж
Вишнумурти Кодумуру
Шифенг Лиу
Наталья Покровская
Вандна Рейна
Шаои Сан
Заигуй Жанг
Original Assignee
Новартис Аг
Ксенон Фармасьютикалз Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39864516&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA96766(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Новартис Аг, Ксенон Фармасьютикалз Инк. filed Critical Новартис Аг
Publication of UA96766C2 publication Critical patent/UA96766C2/ru

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    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • Diabetes (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)

Abstract

В заявке описаны гетероциклические производные, которые модулируют активность стеароил-СоА-десатуразы.В заявке также описаны способы применения таких производных для модулирования активности стеароил-СоА-десатуразы и фармацевтические композиции, которые включают такие производные.
UAA200900859A 2006-08-15 2007-08-13 Гетероциклические соединения, пригодные для лечения болезней, которые имеют отношение к повышенному уровню липидов UA96766C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82245906P 2006-08-15 2006-08-15

Publications (1)

Publication Number Publication Date
UA96766C2 true UA96766C2 (ru) 2011-12-12

Family

ID=39864516

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200900859A UA96766C2 (ru) 2006-08-15 2007-08-13 Гетероциклические соединения, пригодные для лечения болезней, которые имеют отношение к повышенному уровню липидов

Country Status (27)

Country Link
US (2) US8063084B2 (ru)
EP (1) EP2054408B1 (ru)
JP (1) JP4972690B2 (ru)
KR (4) KR20090040385A (ru)
CN (1) CN101535303B (ru)
AR (1) AR062360A1 (ru)
AU (1) AU2007351498B2 (ru)
BR (1) BRPI0716407A2 (ru)
CA (1) CA2660201C (ru)
CL (1) CL2007002348A1 (ru)
CO (1) CO6241156A2 (ru)
CR (1) CR10566A (ru)
ES (1) ES2597453T3 (ru)
GT (1) GT200900027A (ru)
IL (1) IL196562A0 (ru)
MA (1) MA30655B1 (ru)
MX (1) MX2009001634A (ru)
MY (1) MY153263A (ru)
NO (1) NO20091083L (ru)
NZ (2) NZ574222A (ru)
PE (3) PE20081316A1 (ru)
RU (1) RU2009109147A (ru)
TN (1) TN2009000045A1 (ru)
TW (1) TWI404718B (ru)
UA (1) UA96766C2 (ru)
WO (1) WO2008127349A2 (ru)
ZA (1) ZA200900263B (ru)

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US8445505B2 (en) 2008-06-25 2013-05-21 Irm Llc Pyrimidine derivatives as kinase inhibitors
UY31929A (es) 2008-06-25 2010-01-05 Irm Llc Compuestos y composiciones como inhibidores de cinasa
EP2398809B1 (en) 2009-02-17 2015-07-08 Merck Canada Inc. Novel spiro compounds useful as inhibitors of stearoyl-coenzyme a delta-9 desaturase
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US9296719B2 (en) * 2011-07-08 2016-03-29 Indiana University Research And Technology Corporation Compositions and methods for the treatment of norovirus infection
BR112014008590A2 (pt) 2011-10-15 2017-10-24 Genentech Inc métodos de uso de antagonistas de scd1
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